Technology Insight: PET and PET/CT in head and neck tumor staging and radiation therapy planning View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-10

AUTHORS

Steven J Frank, KS Clifford Chao, David L Schwartz, Randal S Weber, Smith Apisarnthanarax, Homer A Macapinlac

ABSTRACT

The evolving utilization of functional imaging, mainly 2-[18F]fluoro-2-deoxyglucose (18FDG) imaging, with positron emission tomography (PET) and PET/CT, is profoundly altering head and neck tumor staging approaches, radiation treatment planning, and follow-up management. Tumor-node-metastasis staging with PET/CT has improved the characterization of patient disease versus CT, MRI, or PET alone, thereby affecting patient disease management. Therefore, the utilization of PET/CT is appropriate for head and neck cancer staging in the initial presentation and in the recurrent setting. In the setting of radiation therapy treatment planning, PET-directed tumor volume contouring is not ready for clinical practice without further technological improvements in imaging specificity/sensitivity and resolution. Patient or organ motion might interfere with the accuracy of anatomical co-alignment, and variability in defining the threshold of imaging signals on PET images can affect the contour of the biological tumor volume. The use of PET/CT for staging and detecting both primary and recurrent head and neck cancer is valuable; however, its application in radiation treatment planning should be viewed as investigational. More... »

PAGES

526

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncponc0322

DOI

http://dx.doi.org/10.1038/ncponc0322

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018386097

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16205772


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