The X-ray crystal structure of the euryarchaeal RNA polymerase in an open-clamp configuration View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Sung-Hoon Jun, Akira Hirata, Tamotsu Kanai, Thomas J. Santangelo, Tadayuki Imanaka, Katsuhiko S. Murakami

ABSTRACT

The archaeal transcription apparatus is closely related to the eukaryotic RNA polymerase II (Pol II) system. Archaeal RNA polymerase (RNAP) and Pol II evolved from a common ancestral structure and the euryarchaeal RNAP is the simplest member of the extant archaeal-eukaryotic RNAP family. Here we report the first crystal structure of euryarchaeal RNAP from Thermococcus kodakarensis (Tko). This structure reveals that the clamp domain is able to swing away from the main body of RNAP in the presence of the Rpo4/Rpo7 stalk by coordinated movements of these domains. More detailed structure-function analysis of yeast Pol II and Tko RNAP identifies structural additions to Pol II that correspond to the binding sites of Pol II-specific general transcription factors including TFIIF, TFIIH and Mediator. Such comparisons provide a framework for dissecting interactions between RNAP and these factors during formation of the pre-initiation complex. More... »

PAGES

5132

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncomms6132

DOI

http://dx.doi.org/10.1038/ncomms6132

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053418817

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25311937


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Archaeal Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Binding Sites", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Crystallography, X-Ray", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA-Directed RNA Polymerases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phylogeny", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomyces cerevisiae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomyces cerevisiae Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Alignment", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thermococcus", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Pennsylvania State University", 
          "id": "https://www.grid.ac/institutes/grid.29857.31", 
          "name": [
            "Department of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jun", 
        "givenName": "Sung-Hoon", 
        "id": "sg:person.01346122705.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346122705.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ehime University", 
          "id": "https://www.grid.ac/institutes/grid.255464.4", 
          "name": [
            "Department of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA", 
            "Department of Materials Science and Biotechnology, Graduate School of Science and Engineering, Ehime University, Matsuyama, Ehime 790-8577, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hirata", 
        "givenName": "Akira", 
        "id": "sg:person.0734102130.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734102130.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510 Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kanai", 
        "givenName": "Tamotsu", 
        "id": "sg:person.0721605175.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721605175.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Colorado State University", 
          "id": "https://www.grid.ac/institutes/grid.47894.36", 
          "name": [
            "Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Santangelo", 
        "givenName": "Thomas J.", 
        "id": "sg:person.0626602033.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626602033.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ritsumeikan University", 
          "id": "https://www.grid.ac/institutes/grid.262576.2", 
          "name": [
            "Department of Biotechnology, Ritsumeikan University, Noji-Higashi, Kusatsu 525-8577, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imanaka", 
        "givenName": "Tadayuki", 
        "id": "sg:person.0700462536.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700462536.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pennsylvania State University", 
          "id": "https://www.grid.ac/institutes/grid.29857.31", 
          "name": [
            "Department of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Murakami", 
        "givenName": "Katsuhiko S.", 
        "id": "sg:person.01023761331.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023761331.66"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1126/science.1200188", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001958304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb1026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002590162", 
          "https://doi.org/10.1038/nsmb1026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb1026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002590162", 
          "https://doi.org/10.1038/nsmb1026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/emboj.2011.64", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003524648"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/molbev/mst012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003639932"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb.2334", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003871257", 
          "https://doi.org/10.1038/nsmb.2334"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0076-6879(97)76066-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004907170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2958.2008.06430.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004951830"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature12636", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007770397", 
          "https://doi.org/10.1038/nature12636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444903009922", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010165186"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2012.12.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011138874"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1097-2765(02)00598-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011749780"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0801980105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012996738"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0108767390010224", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014210169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.str.2006.09.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014749799"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gks692", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014847392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1059493", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015760622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/emboj.2009.386", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015831494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/emboj.2009.386", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015831494"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06530", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016216700", 
          "https://doi.org/10.1038/nature06530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1215241109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017073577"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1238724", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017230122"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1030608100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019574256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature12779", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020124788", 
          "https://doi.org/10.1038/nature12779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444904019158", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020281098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m413038200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020609552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jmb.2007.08.066", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022859540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m611674200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024013779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molcel.2011.05.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025827087"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pbio.1000102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026091323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444997018805", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026895546"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkp928", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027436503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature12712", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030884628", 
          "https://doi.org/10.1038/nature12712"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb763", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032525772", 
          "https://doi.org/10.1038/nsmb763"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb763", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032525772", 
          "https://doi.org/10.1038/nsmb763"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444900014736", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033401324"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m508253200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034353051"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb.1757", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034423139", 
          "https://doi.org/10.1038/nsmb.1757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb.1757", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034423139", 
          "https://doi.org/10.1038/nsmb.1757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2007.406", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035232696", 
          "https://doi.org/10.1038/nprot.2007.406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1220225110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036613318"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0810647105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036700091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1218716", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038538272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444900005072", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038886912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature11991", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038891424", 
          "https://doi.org/10.1038/nature11991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molcel.2006.05.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040235367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molcel.2012.01.023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043171000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/10409238.2010.538662", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045249418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08892", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045292267", 
          "https://doi.org/10.1038/nature08892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08892", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045292267", 
          "https://doi.org/10.1038/nature08892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.sbi.2009.10.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047619065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0076-6879(97)76075-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048618669"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb1272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048916764", 
          "https://doi.org/10.1038/nsmb1272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444902016657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051282549"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cbpa.2011.07.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051886623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrmicro2507", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053742539", 
          "https://doi.org/10.1038/nrmicro2507"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077975958", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083052719", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-12", 
    "datePublishedReg": "2014-12-01", 
    "description": "The archaeal transcription apparatus is closely related to the eukaryotic RNA polymerase II (Pol II) system. Archaeal RNA polymerase (RNAP) and Pol II evolved from a common ancestral structure and the euryarchaeal RNAP is the simplest member of the extant archaeal-eukaryotic RNAP family. Here we report the first crystal structure of euryarchaeal RNAP from Thermococcus kodakarensis (Tko). This structure reveals that the clamp domain is able to swing away from the main body of RNAP in the presence of the Rpo4/Rpo7 stalk by coordinated movements of these domains. More detailed structure-function analysis of yeast Pol II and Tko RNAP identifies structural additions to Pol II that correspond to the binding sites of Pol II-specific general transcription factors including TFIIF, TFIIH and Mediator. Such comparisons provide a framework for dissecting interactions between RNAP and these factors during formation of the pre-initiation complex. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ncomms6132", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2520394", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3802721", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6108154", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2521566", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6142590", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1043282", 
        "issn": [
          "2041-1723"
        ], 
        "name": "Nature Communications", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "5"
      }
    ], 
    "name": "The X-ray crystal structure of the euryarchaeal RNA polymerase in an open-clamp configuration", 
    "pagination": "5132", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "fe70b948f65ba58eab0fc26720b3fa73616995239cf10ea8af2dbf96d39f18fc"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25311937"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101528555"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ncomms6132"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1053418817"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ncomms6132", 
      "https://app.dimensions.ai/details/publication/pub.1053418817"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:20", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000436.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/ncomms6132"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ncomms6132'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ncomms6132'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ncomms6132'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ncomms6132'


 

This table displays all metadata directly associated to this object as RDF triples.

340 TRIPLES      21 PREDICATES      93 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ncomms6132 schema:about N0ecee48785d2486f825745ca89b39dc6
2 N1d57de36e0184391b2e16a15b94f56b8
3 N49d47c02b36f49b19253b87e5212ed2a
4 N8bcf2dbf0910423baa067713677b1ce5
5 N978d2ecf04a44ec98be5f4d911054965
6 Nb0d329a7bcda4da7b32ba38dee19aeb3
7 Nbaf25b7cbd414c0c800386939f5402be
8 Nc635e5207ba04cdd8ebb4e61b3bd482f
9 Ncdd56053a6d747a284ae297fc609c697
10 Nebbe5399e0f446c7bdb967758b9bfbc1
11 Nffba97bc9658420c8ae796238dc5958a
12 anzsrc-for:06
13 anzsrc-for:0601
14 schema:author Nab472985c43647fb8cc5d7dec634678f
15 schema:citation sg:pub.10.1038/nature06530
16 sg:pub.10.1038/nature08892
17 sg:pub.10.1038/nature11991
18 sg:pub.10.1038/nature12636
19 sg:pub.10.1038/nature12712
20 sg:pub.10.1038/nature12779
21 sg:pub.10.1038/nprot.2007.406
22 sg:pub.10.1038/nrmicro2507
23 sg:pub.10.1038/nsmb.1757
24 sg:pub.10.1038/nsmb.2334
25 sg:pub.10.1038/nsmb1026
26 sg:pub.10.1038/nsmb1272
27 sg:pub.10.1038/nsmb763
28 https://app.dimensions.ai/details/publication/pub.1077975958
29 https://app.dimensions.ai/details/publication/pub.1083052719
30 https://doi.org/10.1016/j.cbpa.2011.07.017
31 https://doi.org/10.1016/j.cell.2012.12.020
32 https://doi.org/10.1016/j.jmb.2007.08.066
33 https://doi.org/10.1016/j.molcel.2006.05.013
34 https://doi.org/10.1016/j.molcel.2011.05.030
35 https://doi.org/10.1016/j.molcel.2012.01.023
36 https://doi.org/10.1016/j.sbi.2009.10.006
37 https://doi.org/10.1016/j.str.2006.09.011
38 https://doi.org/10.1016/s0076-6879(97)76066-x
39 https://doi.org/10.1016/s0076-6879(97)76075-0
40 https://doi.org/10.1016/s1097-2765(02)00598-1
41 https://doi.org/10.1038/emboj.2009.386
42 https://doi.org/10.1038/emboj.2011.64
43 https://doi.org/10.1073/pnas.0801980105
44 https://doi.org/10.1073/pnas.0810647105
45 https://doi.org/10.1073/pnas.1030608100
46 https://doi.org/10.1073/pnas.1215241109
47 https://doi.org/10.1073/pnas.1220225110
48 https://doi.org/10.1074/jbc.m413038200
49 https://doi.org/10.1074/jbc.m508253200
50 https://doi.org/10.1074/jbc.m611674200
51 https://doi.org/10.1093/molbev/mst012
52 https://doi.org/10.1093/nar/gkp928
53 https://doi.org/10.1093/nar/gks692
54 https://doi.org/10.1107/s0108767390010224
55 https://doi.org/10.1107/s0907444900005072
56 https://doi.org/10.1107/s0907444900014736
57 https://doi.org/10.1107/s0907444902016657
58 https://doi.org/10.1107/s0907444903009922
59 https://doi.org/10.1107/s0907444904019158
60 https://doi.org/10.1107/s0907444997018805
61 https://doi.org/10.1111/j.1365-2958.2008.06430.x
62 https://doi.org/10.1126/science.1059493
63 https://doi.org/10.1126/science.1200188
64 https://doi.org/10.1126/science.1218716
65 https://doi.org/10.1126/science.1238724
66 https://doi.org/10.1371/journal.pbio.1000102
67 https://doi.org/10.3109/10409238.2010.538662
68 schema:datePublished 2014-12
69 schema:datePublishedReg 2014-12-01
70 schema:description The archaeal transcription apparatus is closely related to the eukaryotic RNA polymerase II (Pol II) system. Archaeal RNA polymerase (RNAP) and Pol II evolved from a common ancestral structure and the euryarchaeal RNAP is the simplest member of the extant archaeal-eukaryotic RNAP family. Here we report the first crystal structure of euryarchaeal RNAP from Thermococcus kodakarensis (Tko). This structure reveals that the clamp domain is able to swing away from the main body of RNAP in the presence of the Rpo4/Rpo7 stalk by coordinated movements of these domains. More detailed structure-function analysis of yeast Pol II and Tko RNAP identifies structural additions to Pol II that correspond to the binding sites of Pol II-specific general transcription factors including TFIIF, TFIIH and Mediator. Such comparisons provide a framework for dissecting interactions between RNAP and these factors during formation of the pre-initiation complex.
71 schema:genre research_article
72 schema:inLanguage en
73 schema:isAccessibleForFree true
74 schema:isPartOf N6716812ba1854c63a5c8533c568c5cba
75 Nd0a781dd935547d6ba35e5e17594994c
76 sg:journal.1043282
77 schema:name The X-ray crystal structure of the euryarchaeal RNA polymerase in an open-clamp configuration
78 schema:pagination 5132
79 schema:productId N157f4d6b96984c8f84fafc9a3b9676d2
80 N2ce6f81659884b5e84ff4c548acc50dd
81 N656941fcaf3c493eb4caf5cfd50e973f
82 Na092d0e6d7b74200b44855217f9870bd
83 Nd7b580c513f64ba3beae1f283f4da1e8
84 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053418817
85 https://doi.org/10.1038/ncomms6132
86 schema:sdDatePublished 2019-04-10T17:20
87 schema:sdLicense https://scigraph.springernature.com/explorer/license/
88 schema:sdPublisher N2bf45065e20e43fc914ef7b53ab77747
89 schema:url https://www.nature.com/articles/ncomms6132
90 sgo:license sg:explorer/license/
91 sgo:sdDataset articles
92 rdf:type schema:ScholarlyArticle
93 N0ecee48785d2486f825745ca89b39dc6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Saccharomyces cerevisiae
95 rdf:type schema:DefinedTerm
96 N157f4d6b96984c8f84fafc9a3b9676d2 schema:name dimensions_id
97 schema:value pub.1053418817
98 rdf:type schema:PropertyValue
99 N1b196a7beeb749d9b19bdd1692549f67 rdf:first sg:person.01023761331.66
100 rdf:rest rdf:nil
101 N1d57de36e0184391b2e16a15b94f56b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Thermococcus
103 rdf:type schema:DefinedTerm
104 N2bf45065e20e43fc914ef7b53ab77747 schema:name Springer Nature - SN SciGraph project
105 rdf:type schema:Organization
106 N2ce6f81659884b5e84ff4c548acc50dd schema:name readcube_id
107 schema:value fe70b948f65ba58eab0fc26720b3fa73616995239cf10ea8af2dbf96d39f18fc
108 rdf:type schema:PropertyValue
109 N49d47c02b36f49b19253b87e5212ed2a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Archaeal Proteins
111 rdf:type schema:DefinedTerm
112 N656941fcaf3c493eb4caf5cfd50e973f schema:name doi
113 schema:value 10.1038/ncomms6132
114 rdf:type schema:PropertyValue
115 N6716812ba1854c63a5c8533c568c5cba schema:issueNumber 1
116 rdf:type schema:PublicationIssue
117 N684da8e51a784cc2801f3be3007330f5 rdf:first sg:person.0626602033.07
118 rdf:rest N6d962c69eeba4a318ebf783bcac4a931
119 N6d962c69eeba4a318ebf783bcac4a931 rdf:first sg:person.0700462536.36
120 rdf:rest N1b196a7beeb749d9b19bdd1692549f67
121 N8bcf2dbf0910423baa067713677b1ce5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Amino Acid Sequence
123 rdf:type schema:DefinedTerm
124 N8d4bb6fd673d45488a5c037d5caedcb6 rdf:first sg:person.0721605175.45
125 rdf:rest N684da8e51a784cc2801f3be3007330f5
126 N978d2ecf04a44ec98be5f4d911054965 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Phylogeny
128 rdf:type schema:DefinedTerm
129 Na092d0e6d7b74200b44855217f9870bd schema:name pubmed_id
130 schema:value 25311937
131 rdf:type schema:PropertyValue
132 Nab472985c43647fb8cc5d7dec634678f rdf:first sg:person.01346122705.31
133 rdf:rest Nf6d414e8fb9445e29d9da3d466266a8e
134 Nb0d329a7bcda4da7b32ba38dee19aeb3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Binding Sites
136 rdf:type schema:DefinedTerm
137 Nbaf25b7cbd414c0c800386939f5402be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Models, Molecular
139 rdf:type schema:DefinedTerm
140 Nc635e5207ba04cdd8ebb4e61b3bd482f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Saccharomyces cerevisiae Proteins
142 rdf:type schema:DefinedTerm
143 Ncdd56053a6d747a284ae297fc609c697 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name DNA-Directed RNA Polymerases
145 rdf:type schema:DefinedTerm
146 Nd0a781dd935547d6ba35e5e17594994c schema:volumeNumber 5
147 rdf:type schema:PublicationVolume
148 Nd7b580c513f64ba3beae1f283f4da1e8 schema:name nlm_unique_id
149 schema:value 101528555
150 rdf:type schema:PropertyValue
151 Nebbe5399e0f446c7bdb967758b9bfbc1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Crystallography, X-Ray
153 rdf:type schema:DefinedTerm
154 Nf6d414e8fb9445e29d9da3d466266a8e rdf:first sg:person.0734102130.75
155 rdf:rest N8d4bb6fd673d45488a5c037d5caedcb6
156 Nffba97bc9658420c8ae796238dc5958a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Sequence Alignment
158 rdf:type schema:DefinedTerm
159 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
160 schema:name Biological Sciences
161 rdf:type schema:DefinedTerm
162 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
163 schema:name Biochemistry and Cell Biology
164 rdf:type schema:DefinedTerm
165 sg:grant.2520394 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms6132
166 rdf:type schema:MonetaryGrant
167 sg:grant.2521566 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms6132
168 rdf:type schema:MonetaryGrant
169 sg:grant.3802721 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms6132
170 rdf:type schema:MonetaryGrant
171 sg:grant.6108154 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms6132
172 rdf:type schema:MonetaryGrant
173 sg:grant.6142590 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms6132
174 rdf:type schema:MonetaryGrant
175 sg:journal.1043282 schema:issn 2041-1723
176 schema:name Nature Communications
177 rdf:type schema:Periodical
178 sg:person.01023761331.66 schema:affiliation https://www.grid.ac/institutes/grid.29857.31
179 schema:familyName Murakami
180 schema:givenName Katsuhiko S.
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023761331.66
182 rdf:type schema:Person
183 sg:person.01346122705.31 schema:affiliation https://www.grid.ac/institutes/grid.29857.31
184 schema:familyName Jun
185 schema:givenName Sung-Hoon
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346122705.31
187 rdf:type schema:Person
188 sg:person.0626602033.07 schema:affiliation https://www.grid.ac/institutes/grid.47894.36
189 schema:familyName Santangelo
190 schema:givenName Thomas J.
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626602033.07
192 rdf:type schema:Person
193 sg:person.0700462536.36 schema:affiliation https://www.grid.ac/institutes/grid.262576.2
194 schema:familyName Imanaka
195 schema:givenName Tadayuki
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700462536.36
197 rdf:type schema:Person
198 sg:person.0721605175.45 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
199 schema:familyName Kanai
200 schema:givenName Tamotsu
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721605175.45
202 rdf:type schema:Person
203 sg:person.0734102130.75 schema:affiliation https://www.grid.ac/institutes/grid.255464.4
204 schema:familyName Hirata
205 schema:givenName Akira
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734102130.75
207 rdf:type schema:Person
208 sg:pub.10.1038/nature06530 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016216700
209 https://doi.org/10.1038/nature06530
210 rdf:type schema:CreativeWork
211 sg:pub.10.1038/nature08892 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045292267
212 https://doi.org/10.1038/nature08892
213 rdf:type schema:CreativeWork
214 sg:pub.10.1038/nature11991 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038891424
215 https://doi.org/10.1038/nature11991
216 rdf:type schema:CreativeWork
217 sg:pub.10.1038/nature12636 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007770397
218 https://doi.org/10.1038/nature12636
219 rdf:type schema:CreativeWork
220 sg:pub.10.1038/nature12712 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030884628
221 https://doi.org/10.1038/nature12712
222 rdf:type schema:CreativeWork
223 sg:pub.10.1038/nature12779 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020124788
224 https://doi.org/10.1038/nature12779
225 rdf:type schema:CreativeWork
226 sg:pub.10.1038/nprot.2007.406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035232696
227 https://doi.org/10.1038/nprot.2007.406
228 rdf:type schema:CreativeWork
229 sg:pub.10.1038/nrmicro2507 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053742539
230 https://doi.org/10.1038/nrmicro2507
231 rdf:type schema:CreativeWork
232 sg:pub.10.1038/nsmb.1757 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034423139
233 https://doi.org/10.1038/nsmb.1757
234 rdf:type schema:CreativeWork
235 sg:pub.10.1038/nsmb.2334 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003871257
236 https://doi.org/10.1038/nsmb.2334
237 rdf:type schema:CreativeWork
238 sg:pub.10.1038/nsmb1026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002590162
239 https://doi.org/10.1038/nsmb1026
240 rdf:type schema:CreativeWork
241 sg:pub.10.1038/nsmb1272 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048916764
242 https://doi.org/10.1038/nsmb1272
243 rdf:type schema:CreativeWork
244 sg:pub.10.1038/nsmb763 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032525772
245 https://doi.org/10.1038/nsmb763
246 rdf:type schema:CreativeWork
247 https://app.dimensions.ai/details/publication/pub.1077975958 schema:CreativeWork
248 https://app.dimensions.ai/details/publication/pub.1083052719 schema:CreativeWork
249 https://doi.org/10.1016/j.cbpa.2011.07.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051886623
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/j.cell.2012.12.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011138874
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/j.jmb.2007.08.066 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022859540
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/j.molcel.2006.05.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040235367
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/j.molcel.2011.05.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025827087
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/j.molcel.2012.01.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043171000
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/j.sbi.2009.10.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047619065
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/j.str.2006.09.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014749799
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1016/s0076-6879(97)76066-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004907170
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1016/s0076-6879(97)76075-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048618669
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/s1097-2765(02)00598-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011749780
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1038/emboj.2009.386 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015831494
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1038/emboj.2011.64 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003524648
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1073/pnas.0801980105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012996738
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1073/pnas.0810647105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036700091
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1073/pnas.1030608100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019574256
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1073/pnas.1215241109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017073577
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1073/pnas.1220225110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036613318
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1074/jbc.m413038200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020609552
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1074/jbc.m508253200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034353051
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1074/jbc.m611674200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024013779
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1093/molbev/mst012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003639932
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1093/nar/gkp928 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027436503
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1093/nar/gks692 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014847392
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1107/s0108767390010224 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014210169
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1107/s0907444900005072 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038886912
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1107/s0907444900014736 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033401324
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1107/s0907444902016657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051282549
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1107/s0907444903009922 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010165186
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1107/s0907444904019158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020281098
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1107/s0907444997018805 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026895546
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1111/j.1365-2958.2008.06430.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004951830
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1126/science.1059493 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015760622
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1126/science.1200188 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001958304
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1126/science.1218716 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038538272
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1126/science.1238724 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017230122
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1371/journal.pbio.1000102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026091323
322 rdf:type schema:CreativeWork
323 https://doi.org/10.3109/10409238.2010.538662 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045249418
324 rdf:type schema:CreativeWork
325 https://www.grid.ac/institutes/grid.255464.4 schema:alternateName Ehime University
326 schema:name Department of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
327 Department of Materials Science and Biotechnology, Graduate School of Science and Engineering, Ehime University, Matsuyama, Ehime 790-8577, Japan
328 rdf:type schema:Organization
329 https://www.grid.ac/institutes/grid.258799.8 schema:alternateName Kyoto University
330 schema:name Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510 Japan
331 rdf:type schema:Organization
332 https://www.grid.ac/institutes/grid.262576.2 schema:alternateName Ritsumeikan University
333 schema:name Department of Biotechnology, Ritsumeikan University, Noji-Higashi, Kusatsu 525-8577, Japan
334 rdf:type schema:Organization
335 https://www.grid.ac/institutes/grid.29857.31 schema:alternateName Pennsylvania State University
336 schema:name Department of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
337 rdf:type schema:Organization
338 https://www.grid.ac/institutes/grid.47894.36 schema:alternateName Colorado State University
339 schema:name Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
340 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...