Individual diet has sex-dependent effects on vertebrate gut microbiota View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-07-29

AUTHORS

Daniel I. Bolnick, Lisa K. Snowberg, Philipp E. Hirsch, Christian L. Lauber, Elin Org, Brian Parks, Aldons J. Lusis, Rob Knight, J. Gregory Caporaso, Richard Svanbäck

ABSTRACT

Vertebrates harbour diverse communities of symbiotic gut microbes. Host diet is known to alter microbiota composition, implying that dietary treatments might alleviate diseases arising from altered microbial composition ('dysbiosis'). However, it remains unclear whether diet effects are general or depend on host genotype. Here we show that gut microbiota composition depends on interactions between host diet and sex within populations of wild and laboratory fish, laboratory mice and humans. Within each of two natural fish populations (threespine stickleback and Eurasian perch), among-individual diet variation is correlated with individual differences in gut microbiota. However, these diet-microbiota associations are sex dependent. We document similar sex-specific diet-microbiota correlations in humans. Experimental diet manipulations in laboratory stickleback and mice confirmed that diet affects microbiota differently in males versus females. The prevalence of such genotype by environment (sex by diet) interactions implies that therapies to treat dysbiosis might have sex-specific effects. More... »

PAGES

4500

References to SciGraph publications

  • 2013-10-17. Fish gut microbiota analysis differentiates physiology and behavior of invasive Asian carp and indigenous American fish in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2013-08-25. Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences in NATURE BIOTECHNOLOGY
  • 2010-12-17. Diet, gut microbiota and immune responses in NATURE IMMUNOLOGY
  • 2012-03-08. Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2011-03-16. Unravelling the effects of the environment and host genotype on the gut microbiome in NATURE REVIEWS MICROBIOLOGY
  • 2010-04-11. QIIME allows analysis of high-throughput community sequencing data in NATURE METHODS
  • 2007-03-14. Using δ13C stable isotopes to quantify individual-level diet variation in OECOLOGIA
  • 2011-12-16. Experimental and analytical tools for studying the human microbiome in NATURE REVIEWS GENETICS
  • 2013-07-10. Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota in NATURE
  • 2010-07-08. Toward defining the autoimmune microbiome for type 1 diabetes in THE ISME JOURNAL: MULTIDISCIPLINARY JOURNAL OF MICROBIAL ECOLOGY
  • 2008-10. Worlds within worlds: evolution of the vertebrate gut microbiota in NATURE REVIEWS MICROBIOLOGY
  • 2013-04-07. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis in NATURE MEDICINE
  • 2006. Stable Isotope Ecology in NONE
  • 2010-12-23. Genotype Is a Stronger Determinant than Sex of the Mouse Gut Microbiota in MICROBIAL ECOLOGY
  • 2013-12-11. Diet rapidly and reproducibly alters the human gut microbiome in NATURE
  • 2008-12-05. Change of Intestinal Microbiota with Elemental Diet and Its Impact on Therapeutic Effects in a Murine Model of Chronic Colitis in DIGESTIVE DISEASES AND SCIENCES
  • 2011-09-21. Peripheral education of the immune system by colonic commensal microbiota in NATURE
  • Journal

    TITLE

    Nature Communications

    ISSUE

    1

    VOLUME

    5

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ncomms5500

    DOI

    http://dx.doi.org/10.1038/ncomms5500

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1026457988

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25072318


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0602", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Ecology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0605", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Microbiology", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Analysis of Variance", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Base Sequence", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "DNA Primers", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Diet", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Dysbiosis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gastrointestinal Tract", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Microbiota", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Molecular Sequence Data", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Perches", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Phenotype", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "RNA, Ribosomal, 16S", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sequence Analysis, DNA", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sex Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Smegmamorpha", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Species Specificity", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Howard Hughes Medical Institute and Department of Integrative Biology, University of Texas at Austin, One University Station C0990, Austin, Texas 78712, USA", 
              "id": "http://www.grid.ac/institutes/grid.89336.37", 
              "name": [
                "Howard Hughes Medical Institute and Department of Integrative Biology, University of Texas at Austin, One University Station C0990, Austin, Texas 78712, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bolnick", 
            "givenName": "Daniel I.", 
            "id": "sg:person.01101767202.20", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101767202.20"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Integrative Biology, University of Texas at Austin, One University Station C0990, Austin, Texas 78712, USA", 
              "id": "http://www.grid.ac/institutes/grid.89336.37", 
              "name": [
                "Department of Integrative Biology, University of Texas at Austin, One University Station C0990, Austin, Texas 78712, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Snowberg", 
            "givenName": "Lisa K.", 
            "id": "sg:person.01060173057.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060173057.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Program Man-Society-Environment, University of Basel, Vesalgasse 1, CH-4051 Basel, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.6612.3", 
              "name": [
                "Department of Ecology and Genetics, Uppsala University, Norbyv\u00e4gen 18D, SE-752 36 Uppsala, Sweden", 
                "Program Man-Society-Environment, University of Basel, Vesalgasse 1, CH-4051 Basel, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hirsch", 
            "givenName": "Philipp E.", 
            "id": "sg:person.01147024573.69", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01147024573.69"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado 80309-0216, USA", 
              "id": "http://www.grid.ac/institutes/grid.464551.7", 
              "name": [
                "Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado 80309-0216, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lauber", 
            "givenName": "Christian L.", 
            "id": "sg:person.01172202331.77", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172202331.77"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Medicine/Division of Cardiology, University of California, Los Angeles, California 90095-1675, USA", 
              "id": "http://www.grid.ac/institutes/grid.19006.3e", 
              "name": [
                "Department of Medicine/Division of Cardiology, University of California, Los Angeles, California 90095-1675, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Org", 
            "givenName": "Elin", 
            "id": "sg:person.01362743133.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362743133.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Medicine/Division of Cardiology, University of California, Los Angeles, California 90095-1675, USA", 
              "id": "http://www.grid.ac/institutes/grid.19006.3e", 
              "name": [
                "Department of Medicine/Division of Cardiology, University of California, Los Angeles, California 90095-1675, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Parks", 
            "givenName": "Brian", 
            "id": "sg:person.01030545676.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030545676.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Medicine/Division of Cardiology, University of California, Los Angeles, California 90095-1675, USA", 
              "id": "http://www.grid.ac/institutes/grid.19006.3e", 
              "name": [
                "Department of Medicine/Division of Cardiology, University of California, Los Angeles, California 90095-1675, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lusis", 
            "givenName": "Aldons J.", 
            "id": "sg:person.07605467557.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07605467557.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Howard Hughes Medical Institute and Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, Colorado 80309-0215, USA", 
              "id": "http://www.grid.ac/institutes/grid.266190.a", 
              "name": [
                "Howard Hughes Medical Institute and Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, Colorado 80309-0215, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Knight", 
            "givenName": "Rob", 
            "id": "sg:person.016311745377.96", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016311745377.96"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute for Genomics and Systems Biology, Argonne National Laboratory, Argonne, Illinois 60439, USA", 
              "id": "http://www.grid.ac/institutes/grid.187073.a", 
              "name": [
                "Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona 86011, USA", 
                "Institute for Genomics and Systems Biology, Argonne National Laboratory, Argonne, Illinois 60439, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Caporaso", 
            "givenName": "J. Gregory", 
            "id": "sg:person.0624224157.70", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624224157.70"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Ecology and Genetics, Uppsala University, Norbyv\u00e4gen 18D, SE-752 36 Uppsala, Sweden", 
              "id": "http://www.grid.ac/institutes/grid.8993.b", 
              "name": [
                "Department of Ecology and Genetics, Uppsala University, Norbyv\u00e4gen 18D, SE-752 36 Uppsala, Sweden"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Svanb\u00e4ck", 
            "givenName": "Richard", 
            "id": "sg:person.0771525726.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771525726.55"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/ismej.2013.181", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051878043", 
              "https://doi.org/10.1038/ismej.2013.181"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ismej.2012.8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038992953", 
              "https://doi.org/10.1038/ismej.2012.8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg3129", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019355616", 
              "https://doi.org/10.1038/nrg3129"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2676", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034019934", 
              "https://doi.org/10.1038/nbt.2676"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro1978", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015675255", 
              "https://doi.org/10.1038/nrmicro1978"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00248-010-9787-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010168710", 
              "https://doi.org/10.1007/s00248-010-9787-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni0111-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052201548", 
              "https://doi.org/10.1038/ni0111-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ismej.2010.92", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039284129", 
              "https://doi.org/10.1038/ismej.2010.92"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.f.303", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009032055", 
              "https://doi.org/10.1038/nmeth.f.303"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/0-387-33745-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019368444", 
              "https://doi.org/10.1007/0-387-33745-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature10434", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010327965", 
              "https://doi.org/10.1038/nature10434"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00442-007-0687-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006806343", 
              "https://doi.org/10.1007/s00442-007-0687-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12820", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013830289", 
              "https://doi.org/10.1038/nature12820"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm.3145", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004485531", 
              "https://doi.org/10.1038/nm.3145"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10620-008-0574-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044460150", 
              "https://doi.org/10.1007/s10620-008-0574-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro2540", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045931365", 
              "https://doi.org/10.1038/nrmicro2540"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12331", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021980193", 
              "https://doi.org/10.1038/nature12331"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2014-07-29", 
        "datePublishedReg": "2014-07-29", 
        "description": "Vertebrates harbour diverse communities of symbiotic gut microbes. Host diet is known to alter microbiota composition, implying that dietary treatments might alleviate diseases arising from altered microbial composition ('dysbiosis'). However, it remains unclear whether diet effects are general or depend on host genotype. Here we show that gut microbiota composition depends on interactions between host diet and sex within populations of wild and laboratory fish, laboratory mice and humans. Within each of two natural fish populations (threespine stickleback and Eurasian perch), among-individual diet variation is correlated with individual differences in gut microbiota. However, these diet-microbiota associations are sex dependent. We document similar sex-specific diet-microbiota correlations in humans. Experimental diet manipulations in laboratory stickleback and mice confirmed that diet affects microbiota differently in males versus females. The prevalence of such genotype by environment (sex by diet) interactions implies that therapies to treat dysbiosis might have sex-specific effects. ", 
        "genre": "article", 
        "id": "sg:pub.10.1038/ncomms5500", 
        "inLanguage": "en", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2684252", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2436755", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2436772", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1043282", 
            "issn": [
              "2041-1723"
            ], 
            "name": "Nature Communications", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "5"
          }
        ], 
        "keywords": [
          "host diet", 
          "symbiotic gut microbes", 
          "individual diet variation", 
          "vertebrate gut microbiota", 
          "natural fish populations", 
          "altered microbial composition", 
          "diet variation", 
          "fish populations", 
          "host genotype", 
          "gut microbiota", 
          "laboratory fish", 
          "microbial composition", 
          "gut microbes", 
          "microbiota composition", 
          "environment interaction", 
          "diverse communities", 
          "such genotypes", 
          "sex-specific effects", 
          "diet manipulation", 
          "microbiota", 
          "laboratory mice", 
          "gut microbiota composition", 
          "genotypes", 
          "vertebrates", 
          "individual diets", 
          "stickleback", 
          "sex-dependent effects", 
          "microbes", 
          "diet effects", 
          "fish", 
          "humans", 
          "population", 
          "mice", 
          "interaction", 
          "composition", 
          "diet", 
          "community", 
          "females", 
          "manipulation", 
          "dysbiosis", 
          "variation", 
          "males", 
          "effect", 
          "sex", 
          "association", 
          "disease", 
          "differences", 
          "dietary treatments", 
          "treatment", 
          "correlation", 
          "individual differences", 
          "therapy", 
          "prevalence", 
          "diet-microbiota associations", 
          "similar sex-specific diet-microbiota correlations", 
          "sex-specific diet-microbiota correlations", 
          "diet-microbiota correlations", 
          "Experimental diet manipulations", 
          "laboratory stickleback"
        ], 
        "name": "Individual diet has sex-dependent effects on vertebrate gut microbiota", 
        "pagination": "4500", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1026457988"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/ncomms5500"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "25072318"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/ncomms5500", 
          "https://app.dimensions.ai/details/publication/pub.1026457988"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2021-12-01T19:31", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_633.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/ncomms5500"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ncomms5500'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ncomms5500'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ncomms5500'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ncomms5500'


     

    This table displays all metadata directly associated to this object as RDF triples.

    363 TRIPLES      22 PREDICATES      123 URIs      97 LITERALS      27 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/ncomms5500 schema:about N0f9b0fc868b74d1db6e3bdf9d8726d46
    2 N201f5338c5c1442fb95f665b34247272
    3 N2c0585809d5c4cf0b433d6acd96b6937
    4 N2e05b9f1e3ed4933bc4d2905928ef99c
    5 N5084de4732fd4473acf3cc7a441a2591
    6 N62349857ca4c47c8af92ef506d962d64
    7 N6ad7f34384e842d68ac4b4d97e5cb4f7
    8 N740e685325aa45419e77d3503fb71efa
    9 N7efc2878ed874ce68a79244e7eb21b5b
    10 N8150c23b17c9437cab6c4c9797732fcd
    11 N850fbcd87573426b969c685c12856f66
    12 N8dcaf8c695414a4fb37b9ef5188780eb
    13 Na8ed209864ca4e90897fe710e7992114
    14 Nab37c6dddcec41b1a7240a85f07a7209
    15 Nb4a2966a6bbd44e6bafc2469dbabdfa4
    16 Nb82d1ae7980e4da3b12238c46d44cb36
    17 Nc52ab15eea2b4034895f3efa13a8385e
    18 Nd801837067014257b6cb7ca039ec5e58
    19 Nf16c4851a780406c9704604789aa58ee
    20 Nfd91e001e5a64bdba5b846c119d1591e
    21 anzsrc-for:06
    22 anzsrc-for:0602
    23 anzsrc-for:0605
    24 schema:author N1238f2f5ea2e43b8b080f0cf466d545b
    25 schema:citation sg:pub.10.1007/0-387-33745-8
    26 sg:pub.10.1007/s00248-010-9787-2
    27 sg:pub.10.1007/s00442-007-0687-1
    28 sg:pub.10.1007/s10620-008-0574-6
    29 sg:pub.10.1038/ismej.2010.92
    30 sg:pub.10.1038/ismej.2012.8
    31 sg:pub.10.1038/ismej.2013.181
    32 sg:pub.10.1038/nature10434
    33 sg:pub.10.1038/nature12331
    34 sg:pub.10.1038/nature12820
    35 sg:pub.10.1038/nbt.2676
    36 sg:pub.10.1038/ni0111-5
    37 sg:pub.10.1038/nm.3145
    38 sg:pub.10.1038/nmeth.f.303
    39 sg:pub.10.1038/nrg3129
    40 sg:pub.10.1038/nrmicro1978
    41 sg:pub.10.1038/nrmicro2540
    42 schema:datePublished 2014-07-29
    43 schema:datePublishedReg 2014-07-29
    44 schema:description Vertebrates harbour diverse communities of symbiotic gut microbes. Host diet is known to alter microbiota composition, implying that dietary treatments might alleviate diseases arising from altered microbial composition ('dysbiosis'). However, it remains unclear whether diet effects are general or depend on host genotype. Here we show that gut microbiota composition depends on interactions between host diet and sex within populations of wild and laboratory fish, laboratory mice and humans. Within each of two natural fish populations (threespine stickleback and Eurasian perch), among-individual diet variation is correlated with individual differences in gut microbiota. However, these diet-microbiota associations are sex dependent. We document similar sex-specific diet-microbiota correlations in humans. Experimental diet manipulations in laboratory stickleback and mice confirmed that diet affects microbiota differently in males versus females. The prevalence of such genotype by environment (sex by diet) interactions implies that therapies to treat dysbiosis might have sex-specific effects.
    45 schema:genre article
    46 schema:inLanguage en
    47 schema:isAccessibleForFree true
    48 schema:isPartOf N7ffdd5fa12d945f5a50c38b324136c29
    49 Ne8818c5f95254a039f950910bccf111b
    50 sg:journal.1043282
    51 schema:keywords Experimental diet manipulations
    52 altered microbial composition
    53 association
    54 community
    55 composition
    56 correlation
    57 diet
    58 diet effects
    59 diet manipulation
    60 diet variation
    61 diet-microbiota associations
    62 diet-microbiota correlations
    63 dietary treatments
    64 differences
    65 disease
    66 diverse communities
    67 dysbiosis
    68 effect
    69 environment interaction
    70 females
    71 fish
    72 fish populations
    73 genotypes
    74 gut microbes
    75 gut microbiota
    76 gut microbiota composition
    77 host diet
    78 host genotype
    79 humans
    80 individual diet variation
    81 individual diets
    82 individual differences
    83 interaction
    84 laboratory fish
    85 laboratory mice
    86 laboratory stickleback
    87 males
    88 manipulation
    89 mice
    90 microbes
    91 microbial composition
    92 microbiota
    93 microbiota composition
    94 natural fish populations
    95 population
    96 prevalence
    97 sex
    98 sex-dependent effects
    99 sex-specific diet-microbiota correlations
    100 sex-specific effects
    101 similar sex-specific diet-microbiota correlations
    102 stickleback
    103 such genotypes
    104 symbiotic gut microbes
    105 therapy
    106 treatment
    107 variation
    108 vertebrate gut microbiota
    109 vertebrates
    110 schema:name Individual diet has sex-dependent effects on vertebrate gut microbiota
    111 schema:pagination 4500
    112 schema:productId N11c3213ff9d84a0489209b832e24cbba
    113 N70d4faa9c8d242c7a7bbe4cad2e95200
    114 N7c5d41c570f54d609587aa5a4243a92e
    115 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026457988
    116 https://doi.org/10.1038/ncomms5500
    117 schema:sdDatePublished 2021-12-01T19:31
    118 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    119 schema:sdPublisher N8ec9b181b57a4e2e97ee17720208ce62
    120 schema:url https://doi.org/10.1038/ncomms5500
    121 sgo:license sg:explorer/license/
    122 sgo:sdDataset articles
    123 rdf:type schema:ScholarlyArticle
    124 N0f9b0fc868b74d1db6e3bdf9d8726d46 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    125 schema:name Analysis of Variance
    126 rdf:type schema:DefinedTerm
    127 N11c3213ff9d84a0489209b832e24cbba schema:name pubmed_id
    128 schema:value 25072318
    129 rdf:type schema:PropertyValue
    130 N1238f2f5ea2e43b8b080f0cf466d545b rdf:first sg:person.01101767202.20
    131 rdf:rest N8b6036776e7942b5a3208c00a273e70b
    132 N1f02650f94d1430284ba15e75fd43bca rdf:first sg:person.01172202331.77
    133 rdf:rest N28c0c05ff3d248d59be4db6f8ed55bc2
    134 N201f5338c5c1442fb95f665b34247272 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    135 schema:name Sequence Analysis, DNA
    136 rdf:type schema:DefinedTerm
    137 N28c0c05ff3d248d59be4db6f8ed55bc2 rdf:first sg:person.01362743133.05
    138 rdf:rest N6a60f588f3974dc6bfb7e212c9301cff
    139 N2c0585809d5c4cf0b433d6acd96b6937 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    140 schema:name Base Sequence
    141 rdf:type schema:DefinedTerm
    142 N2e05b9f1e3ed4933bc4d2905928ef99c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    143 schema:name Humans
    144 rdf:type schema:DefinedTerm
    145 N404679880fe244c7b375c2e7e6e8428d rdf:first sg:person.016311745377.96
    146 rdf:rest Nd66fb77581f94673a69ca3e6f8f832aa
    147 N5084de4732fd4473acf3cc7a441a2591 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    148 schema:name Animals
    149 rdf:type schema:DefinedTerm
    150 N62349857ca4c47c8af92ef506d962d64 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    151 schema:name Male
    152 rdf:type schema:DefinedTerm
    153 N6a60f588f3974dc6bfb7e212c9301cff rdf:first sg:person.01030545676.10
    154 rdf:rest Neee47a54169c4cebbff4f89fe3dc9528
    155 N6ad7f34384e842d68ac4b4d97e5cb4f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    156 schema:name Diet
    157 rdf:type schema:DefinedTerm
    158 N70d4faa9c8d242c7a7bbe4cad2e95200 schema:name doi
    159 schema:value 10.1038/ncomms5500
    160 rdf:type schema:PropertyValue
    161 N740e685325aa45419e77d3503fb71efa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    162 schema:name Molecular Sequence Data
    163 rdf:type schema:DefinedTerm
    164 N7c5d41c570f54d609587aa5a4243a92e schema:name dimensions_id
    165 schema:value pub.1026457988
    166 rdf:type schema:PropertyValue
    167 N7efc2878ed874ce68a79244e7eb21b5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    168 schema:name Perches
    169 rdf:type schema:DefinedTerm
    170 N7ffdd5fa12d945f5a50c38b324136c29 schema:volumeNumber 5
    171 rdf:type schema:PublicationVolume
    172 N8150c23b17c9437cab6c4c9797732fcd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    173 schema:name Sex Factors
    174 rdf:type schema:DefinedTerm
    175 N850fbcd87573426b969c685c12856f66 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    176 schema:name RNA, Ribosomal, 16S
    177 rdf:type schema:DefinedTerm
    178 N8b6036776e7942b5a3208c00a273e70b rdf:first sg:person.01060173057.32
    179 rdf:rest Nc70651ef404b4ef6ae9ff198cab559a6
    180 N8dcaf8c695414a4fb37b9ef5188780eb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    181 schema:name Species Specificity
    182 rdf:type schema:DefinedTerm
    183 N8ec9b181b57a4e2e97ee17720208ce62 schema:name Springer Nature - SN SciGraph project
    184 rdf:type schema:Organization
    185 N97f601a75dbf42029773ce5ec4aee966 rdf:first sg:person.0771525726.55
    186 rdf:rest rdf:nil
    187 Na8ed209864ca4e90897fe710e7992114 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    188 schema:name Dysbiosis
    189 rdf:type schema:DefinedTerm
    190 Nab37c6dddcec41b1a7240a85f07a7209 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    191 schema:name DNA Primers
    192 rdf:type schema:DefinedTerm
    193 Nb4a2966a6bbd44e6bafc2469dbabdfa4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    194 schema:name Microbiota
    195 rdf:type schema:DefinedTerm
    196 Nb82d1ae7980e4da3b12238c46d44cb36 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    197 schema:name Female
    198 rdf:type schema:DefinedTerm
    199 Nc52ab15eea2b4034895f3efa13a8385e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    200 schema:name Phenotype
    201 rdf:type schema:DefinedTerm
    202 Nc70651ef404b4ef6ae9ff198cab559a6 rdf:first sg:person.01147024573.69
    203 rdf:rest N1f02650f94d1430284ba15e75fd43bca
    204 Nd66fb77581f94673a69ca3e6f8f832aa rdf:first sg:person.0624224157.70
    205 rdf:rest N97f601a75dbf42029773ce5ec4aee966
    206 Nd801837067014257b6cb7ca039ec5e58 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    207 schema:name Mice
    208 rdf:type schema:DefinedTerm
    209 Ne8818c5f95254a039f950910bccf111b schema:issueNumber 1
    210 rdf:type schema:PublicationIssue
    211 Neee47a54169c4cebbff4f89fe3dc9528 rdf:first sg:person.07605467557.07
    212 rdf:rest N404679880fe244c7b375c2e7e6e8428d
    213 Nf16c4851a780406c9704604789aa58ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    214 schema:name Smegmamorpha
    215 rdf:type schema:DefinedTerm
    216 Nfd91e001e5a64bdba5b846c119d1591e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    217 schema:name Gastrointestinal Tract
    218 rdf:type schema:DefinedTerm
    219 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    220 schema:name Biological Sciences
    221 rdf:type schema:DefinedTerm
    222 anzsrc-for:0602 schema:inDefinedTermSet anzsrc-for:
    223 schema:name Ecology
    224 rdf:type schema:DefinedTerm
    225 anzsrc-for:0605 schema:inDefinedTermSet anzsrc-for:
    226 schema:name Microbiology
    227 rdf:type schema:DefinedTerm
    228 sg:grant.2436755 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms5500
    229 rdf:type schema:MonetaryGrant
    230 sg:grant.2436772 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms5500
    231 rdf:type schema:MonetaryGrant
    232 sg:grant.2684252 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms5500
    233 rdf:type schema:MonetaryGrant
    234 sg:journal.1043282 schema:issn 2041-1723
    235 schema:name Nature Communications
    236 schema:publisher Springer Nature
    237 rdf:type schema:Periodical
    238 sg:person.01030545676.10 schema:affiliation grid-institutes:grid.19006.3e
    239 schema:familyName Parks
    240 schema:givenName Brian
    241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030545676.10
    242 rdf:type schema:Person
    243 sg:person.01060173057.32 schema:affiliation grid-institutes:grid.89336.37
    244 schema:familyName Snowberg
    245 schema:givenName Lisa K.
    246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060173057.32
    247 rdf:type schema:Person
    248 sg:person.01101767202.20 schema:affiliation grid-institutes:grid.89336.37
    249 schema:familyName Bolnick
    250 schema:givenName Daniel I.
    251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101767202.20
    252 rdf:type schema:Person
    253 sg:person.01147024573.69 schema:affiliation grid-institutes:grid.6612.3
    254 schema:familyName Hirsch
    255 schema:givenName Philipp E.
    256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01147024573.69
    257 rdf:type schema:Person
    258 sg:person.01172202331.77 schema:affiliation grid-institutes:grid.464551.7
    259 schema:familyName Lauber
    260 schema:givenName Christian L.
    261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172202331.77
    262 rdf:type schema:Person
    263 sg:person.01362743133.05 schema:affiliation grid-institutes:grid.19006.3e
    264 schema:familyName Org
    265 schema:givenName Elin
    266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362743133.05
    267 rdf:type schema:Person
    268 sg:person.016311745377.96 schema:affiliation grid-institutes:grid.266190.a
    269 schema:familyName Knight
    270 schema:givenName Rob
    271 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016311745377.96
    272 rdf:type schema:Person
    273 sg:person.0624224157.70 schema:affiliation grid-institutes:grid.187073.a
    274 schema:familyName Caporaso
    275 schema:givenName J. Gregory
    276 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624224157.70
    277 rdf:type schema:Person
    278 sg:person.07605467557.07 schema:affiliation grid-institutes:grid.19006.3e
    279 schema:familyName Lusis
    280 schema:givenName Aldons J.
    281 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07605467557.07
    282 rdf:type schema:Person
    283 sg:person.0771525726.55 schema:affiliation grid-institutes:grid.8993.b
    284 schema:familyName Svanbäck
    285 schema:givenName Richard
    286 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771525726.55
    287 rdf:type schema:Person
    288 sg:pub.10.1007/0-387-33745-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019368444
    289 https://doi.org/10.1007/0-387-33745-8
    290 rdf:type schema:CreativeWork
    291 sg:pub.10.1007/s00248-010-9787-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010168710
    292 https://doi.org/10.1007/s00248-010-9787-2
    293 rdf:type schema:CreativeWork
    294 sg:pub.10.1007/s00442-007-0687-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006806343
    295 https://doi.org/10.1007/s00442-007-0687-1
    296 rdf:type schema:CreativeWork
    297 sg:pub.10.1007/s10620-008-0574-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044460150
    298 https://doi.org/10.1007/s10620-008-0574-6
    299 rdf:type schema:CreativeWork
    300 sg:pub.10.1038/ismej.2010.92 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039284129
    301 https://doi.org/10.1038/ismej.2010.92
    302 rdf:type schema:CreativeWork
    303 sg:pub.10.1038/ismej.2012.8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038992953
    304 https://doi.org/10.1038/ismej.2012.8
    305 rdf:type schema:CreativeWork
    306 sg:pub.10.1038/ismej.2013.181 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051878043
    307 https://doi.org/10.1038/ismej.2013.181
    308 rdf:type schema:CreativeWork
    309 sg:pub.10.1038/nature10434 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010327965
    310 https://doi.org/10.1038/nature10434
    311 rdf:type schema:CreativeWork
    312 sg:pub.10.1038/nature12331 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021980193
    313 https://doi.org/10.1038/nature12331
    314 rdf:type schema:CreativeWork
    315 sg:pub.10.1038/nature12820 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013830289
    316 https://doi.org/10.1038/nature12820
    317 rdf:type schema:CreativeWork
    318 sg:pub.10.1038/nbt.2676 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034019934
    319 https://doi.org/10.1038/nbt.2676
    320 rdf:type schema:CreativeWork
    321 sg:pub.10.1038/ni0111-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052201548
    322 https://doi.org/10.1038/ni0111-5
    323 rdf:type schema:CreativeWork
    324 sg:pub.10.1038/nm.3145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004485531
    325 https://doi.org/10.1038/nm.3145
    326 rdf:type schema:CreativeWork
    327 sg:pub.10.1038/nmeth.f.303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009032055
    328 https://doi.org/10.1038/nmeth.f.303
    329 rdf:type schema:CreativeWork
    330 sg:pub.10.1038/nrg3129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019355616
    331 https://doi.org/10.1038/nrg3129
    332 rdf:type schema:CreativeWork
    333 sg:pub.10.1038/nrmicro1978 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015675255
    334 https://doi.org/10.1038/nrmicro1978
    335 rdf:type schema:CreativeWork
    336 sg:pub.10.1038/nrmicro2540 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045931365
    337 https://doi.org/10.1038/nrmicro2540
    338 rdf:type schema:CreativeWork
    339 grid-institutes:grid.187073.a schema:alternateName Institute for Genomics and Systems Biology, Argonne National Laboratory, Argonne, Illinois 60439, USA
    340 schema:name Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona 86011, USA
    341 Institute for Genomics and Systems Biology, Argonne National Laboratory, Argonne, Illinois 60439, USA
    342 rdf:type schema:Organization
    343 grid-institutes:grid.19006.3e schema:alternateName Department of Medicine/Division of Cardiology, University of California, Los Angeles, California 90095-1675, USA
    344 schema:name Department of Medicine/Division of Cardiology, University of California, Los Angeles, California 90095-1675, USA
    345 rdf:type schema:Organization
    346 grid-institutes:grid.266190.a schema:alternateName Howard Hughes Medical Institute and Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, Colorado 80309-0215, USA
    347 schema:name Howard Hughes Medical Institute and Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado, Boulder, Colorado 80309-0215, USA
    348 rdf:type schema:Organization
    349 grid-institutes:grid.464551.7 schema:alternateName Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado 80309-0216, USA
    350 schema:name Cooperative Institute for Research in Environmental Sciences, University of Colorado, Boulder, Colorado 80309-0216, USA
    351 rdf:type schema:Organization
    352 grid-institutes:grid.6612.3 schema:alternateName Program Man-Society-Environment, University of Basel, Vesalgasse 1, CH-4051 Basel, Switzerland
    353 schema:name Department of Ecology and Genetics, Uppsala University, Norbyvägen 18D, SE-752 36 Uppsala, Sweden
    354 Program Man-Society-Environment, University of Basel, Vesalgasse 1, CH-4051 Basel, Switzerland
    355 rdf:type schema:Organization
    356 grid-institutes:grid.89336.37 schema:alternateName Department of Integrative Biology, University of Texas at Austin, One University Station C0990, Austin, Texas 78712, USA
    357 Howard Hughes Medical Institute and Department of Integrative Biology, University of Texas at Austin, One University Station C0990, Austin, Texas 78712, USA
    358 schema:name Department of Integrative Biology, University of Texas at Austin, One University Station C0990, Austin, Texas 78712, USA
    359 Howard Hughes Medical Institute and Department of Integrative Biology, University of Texas at Austin, One University Station C0990, Austin, Texas 78712, USA
    360 rdf:type schema:Organization
    361 grid-institutes:grid.8993.b schema:alternateName Department of Ecology and Genetics, Uppsala University, Norbyvägen 18D, SE-752 36 Uppsala, Sweden
    362 schema:name Department of Ecology and Genetics, Uppsala University, Norbyvägen 18D, SE-752 36 Uppsala, Sweden
    363 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...