Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-03-08

AUTHORS

Stefanie Heilmann-Heimbach, Christine Herold, Lara M. Hochfeld, Axel M. Hillmer, Dale R. Nyholt, Julian Hecker, Asif Javed, Elaine G. Y. Chew, Sonali Pechlivanis, Dmitriy Drichel, Xiu Ting Heng, Ricardo C. -H. del Rosario, Heide L. Fier, Ralf Paus, Rico Rueedi, Tessel E. Galesloot, Susanne Moebus, Thomas Anhalt, Shyam Prabhakar, Rui Li, Stavroula Kanoni, George Papanikolaou, Zoltán Kutalik, Panos Deloukas, Michael P. Philpott, Gérard Waeber, Tim D. Spector, Peter Vollenweider, Lambertus A. L. M. Kiemeney, George Dedoussis, J. Brent Richards, Michael Nothnagel, Nicholas G. Martin, Tim Becker, David A. Hinds, Markus M. Nöthen

ABSTRACT

Male-pattern baldness (MPB) is a common and highly heritable trait characterized by androgen-dependent, progressive hair loss from the scalp. Here, we carry out the largest GWAS meta-analysis of MPB to date, comprising 10,846 early-onset cases and 11,672 controls from eight independent cohorts. We identify 63 MPB-associated loci (P<5 × 10-8, METAL) of which 23 have not been reported previously. The 63 loci explain ∼39% of the phenotypic variance in MPB and highlight several plausible candidate genes (FGF5, IRF4, DKK2) and pathways (melatonin signalling, adipogenesis) that are likely to be implicated in the key-pathophysiological features of MPB and may represent promising targets for the development of novel therapeutic options. The data provide molecular evidence that rather than being an isolated trait, MPB shares a substantial biological basis with numerous other human phenotypes and may deserve evaluation as an early prognostic marker, for example, for prostate cancer, sudden cardiac arrest and neurodegenerative disorders. More... »

PAGES

14694

References to SciGraph publications

  • 2012-06. Dickkopf 1 Promotes Regression of Hair Follicles in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2016-07. Detection and interpretation of shared genetic influences on 42 human traits in NATURE GENETICS
  • 2016-10. Erratum: Detection and interpretation of shared genetic influences on 42 human traits in NATURE GENETICS
  • 2003-12. Genetic Basis of Male Pattern Baldness in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2010-12. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies in NATURE GENETICS
  • 2008-11. Male-pattern baldness susceptibility locus at 20p11 in NATURE GENETICS
  • 2008-11. Susceptibility variants for male-pattern baldness on chromosome 20p11 in NATURE GENETICS
  • 2013-10. Systematic identification of trans eQTLs as putative drivers of known disease associations in NATURE GENETICS
  • 2014-12. Androgens, body fat Distribution and Adipogenesis in CURRENT OBESITY REPORTS
  • 2014-10. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche in NATURE
  • 2013-06. Androgenetic Alopecia: Identification of Four Genetic Risk Loci and Evidence for the Contribution of WNT Signaling to Its Etiology in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2008-07. Two newly identified genetic determinants of pigmentation in Europeans in NATURE GENETICS
  • 2015-12. Biological interpretation of genome-wide association studies using predicted gene functions in NATURE COMMUNICATIONS
  • 2015-11. An atlas of genetic correlations across human diseases and traits in NATURE GENETICS
  • 2014-07. Biological insights from 108 schizophrenia-associated genetic loci in NATURE
  • 2013-08. Validating therapeutic targets through human genetics in NATURE REVIEWS DRUG DISCOVERY
  • 1998-12. Localization of Rat FGF-5 Protein in Skin Macrophage-like Cells and FGF-5S Protein in Hair Follicle: Possible Involvement of two Fgf-5 Gene Products in Hair Growth Cycle Regulation in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2008-02. Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ncomms14694

    DOI

    http://dx.doi.org/10.1038/ncomms14694

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1084128922

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28272467


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany", 
                "Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Heilmann-Heimbach", 
            "givenName": "Stefanie", 
            "id": "sg:person.01122704751.01", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01122704751.01"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "German Center for Neurodegenerative Disorders, 53175 Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Herold", 
            "givenName": "Christine", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany", 
                "Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hochfeld", 
            "givenName": "Lara M.", 
            "id": "sg:person.01163215763.76", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163215763.76"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Translational Oncology", 
              "id": "https://www.grid.ac/institutes/grid.461816.c", 
              "name": [
                "Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore", 
                "TRON-Translational Oncology at the University Medical Center of Johannes Gutenberg University, TRON gGmbH, 55131 Mainz, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hillmer", 
            "givenName": "Axel M.", 
            "id": "sg:person.0713541727.99", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713541727.99"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Queensland University of Technology", 
              "id": "https://www.grid.ac/institutes/grid.1024.7", 
              "name": [
                "Institute of Health and Biomedical Innovation, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nyholt", 
            "givenName": "Dale R.", 
            "id": "sg:person.01034633157.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034633157.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Institute of Genomic Mathematics, University of Bonn, 53127 Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hecker", 
            "givenName": "Julian", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Genome Institute of Singapore", 
              "id": "https://www.grid.ac/institutes/grid.418377.e", 
              "name": [
                "Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Javed", 
            "givenName": "Asif", 
            "id": "sg:person.0634253750.76", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634253750.76"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Genome Institute of Singapore", 
              "id": "https://www.grid.ac/institutes/grid.418377.e", 
              "name": [
                "Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chew", 
            "givenName": "Elaine G. Y.", 
            "id": "sg:person.0675736414.06", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675736414.06"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Duisburg-Essen", 
              "id": "https://www.grid.ac/institutes/grid.5718.b", 
              "name": [
                "Institute of Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-Essen, 45122 Essen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pechlivanis", 
            "givenName": "Sonali", 
            "id": "sg:person.01367101560.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367101560.30"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cologne", 
              "id": "https://www.grid.ac/institutes/grid.6190.e", 
              "name": [
                "Cologne Center for Genomics, University of Cologne, 50931 Cologne, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Drichel", 
            "givenName": "Dmitriy", 
            "id": "sg:person.0770101774.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0770101774.48"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Genome Institute of Singapore", 
              "id": "https://www.grid.ac/institutes/grid.418377.e", 
              "name": [
                "Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Heng", 
            "givenName": "Xiu Ting", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Genome Institute of Singapore", 
              "id": "https://www.grid.ac/institutes/grid.418377.e", 
              "name": [
                "Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore"
              ], 
              "type": "Organization"
            }, 
            "familyName": "del Rosario", 
            "givenName": "Ricardo C. -H.", 
            "id": "sg:person.012460064444.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012460064444.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Institute of Genomic Mathematics, University of Bonn, 53127 Bonn, Germany", 
                "Department of Biostatistics, Harvard School T.H. Chan of Public Health, Boston, Massachusetts 02115, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fier", 
            "givenName": "Heide L.", 
            "id": "sg:person.0677446313.96", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677446313.96"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Manchester", 
              "id": "https://www.grid.ac/institutes/grid.5379.8", 
              "name": [
                "Dermatology Research Centre, Institute of Inflammation and Repair, University of Manchester, Manchester M13 9PL, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Paus", 
            "givenName": "Ralf", 
            "id": "sg:person.01347504124.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347504124.22"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Swiss Institute of Bioinformatics", 
              "id": "https://www.grid.ac/institutes/grid.419765.8", 
              "name": [
                "Department of Computational Biology, University of Lausanne, 1011 Lausanne, Switzerland", 
                "Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rueedi", 
            "givenName": "Rico", 
            "id": "sg:person.016317135745.67", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016317135745.67"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Radboud University Nijmegen Medical Centre", 
              "id": "https://www.grid.ac/institutes/grid.10417.33", 
              "name": [
                "Radboud Institute for Health Sciences, Department for Health Evidence, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Galesloot", 
            "givenName": "Tessel E.", 
            "id": "sg:person.01021200171.47", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021200171.47"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Duisburg-Essen", 
              "id": "https://www.grid.ac/institutes/grid.5718.b", 
              "name": [
                "Institute of Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-Essen, 45122 Essen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Moebus", 
            "givenName": "Susanne", 
            "id": "sg:person.01260346064.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260346064.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany", 
                "Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Anhalt", 
            "givenName": "Thomas", 
            "id": "sg:person.011746451777.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011746451777.08"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Genome Institute of Singapore", 
              "id": "https://www.grid.ac/institutes/grid.418377.e", 
              "name": [
                "Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Prabhakar", 
            "givenName": "Shyam", 
            "id": "sg:person.0700340034.34", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700340034.34"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Centre for Clinical Epidemiology, Departments of Medicine, Genetics and Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, H3T 1E2 Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Li", 
            "givenName": "Rui", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Queen Mary University of London", 
              "id": "https://www.grid.ac/institutes/grid.4868.2", 
              "name": [
                "William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kanoni", 
            "givenName": "Stavroula", 
            "id": "sg:person.01223606626.04", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223606626.04"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Harokopio University", 
              "id": "https://www.grid.ac/institutes/grid.15823.3d", 
              "name": [
                "School of Health Sciences and Education, Department of Nutrition and Dietetics, Harokopio University, Attica, 17671 Kallithea, Greece"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Papanikolaou", 
            "givenName": "George", 
            "id": "sg:person.01222440332.93", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222440332.93"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute of Social and Preventive Medicine", 
              "id": "https://www.grid.ac/institutes/grid.482968.9", 
              "name": [
                "Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland", 
                "Institute of Social and Preventive Medicine, University Hospital of Lausanne, 1010 Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kutalik", 
            "givenName": "Zolt\u00e1n", 
            "id": "sg:person.0740324166.54", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0740324166.54"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "King Abdulaziz University", 
              "id": "https://www.grid.ac/institutes/grid.412125.1", 
              "name": [
                "William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK", 
                "Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 21589, Saudi Arabia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Deloukas", 
            "givenName": "Panos", 
            "id": "sg:person.016466407337.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016466407337.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Queen Mary University of London", 
              "id": "https://www.grid.ac/institutes/grid.4868.2", 
              "name": [
                "Centre for Cell Biology and Cutaneous Research Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Philpott", 
            "givenName": "Michael P.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital of Lausanne", 
              "id": "https://www.grid.ac/institutes/grid.8515.9", 
              "name": [
                "Department of Internal Medicine, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Waeber", 
            "givenName": "G\u00e9rard", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "King's College London", 
              "id": "https://www.grid.ac/institutes/grid.13097.3c", 
              "name": [
                "Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Spector", 
            "givenName": "Tim D.", 
            "id": "sg:person.014424006237.85", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014424006237.85"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital of Lausanne", 
              "id": "https://www.grid.ac/institutes/grid.8515.9", 
              "name": [
                "Department of Internal Medicine, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Vollenweider", 
            "givenName": "Peter", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Radboud University Nijmegen Medical Centre", 
              "id": "https://www.grid.ac/institutes/grid.10417.33", 
              "name": [
                "Radboud Institute for Health Sciences, Department for Health Evidence, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kiemeney", 
            "givenName": "Lambertus A. L. M.", 
            "id": "sg:person.016033704317.28", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016033704317.28"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Harokopio University", 
              "id": "https://www.grid.ac/institutes/grid.15823.3d", 
              "name": [
                "School of Health Sciences and Education, Department of Nutrition and Dietetics, Harokopio University, Attica, 17671 Kallithea, Greece"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dedoussis", 
            "givenName": "George", 
            "id": "sg:person.016023162734.90", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016023162734.90"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "King's College London", 
              "id": "https://www.grid.ac/institutes/grid.13097.3c", 
              "name": [
                "Centre for Clinical Epidemiology, Departments of Medicine, Genetics and Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, H3T 1E2 Canada", 
                "Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Richards", 
            "givenName": "J. Brent", 
            "id": "sg:person.01265671725.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265671725.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cologne", 
              "id": "https://www.grid.ac/institutes/grid.6190.e", 
              "name": [
                "Cologne Center for Genomics, University of Cologne, 50931 Cologne, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nothnagel", 
            "givenName": "Michael", 
            "id": "sg:person.01322130132.87", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322130132.87"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "QIMR Berghofer Medical Research Institute", 
              "id": "https://www.grid.ac/institutes/grid.1049.c", 
              "name": [
                "QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Martin", 
            "givenName": "Nicholas G.", 
            "id": "sg:person.010700366647.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010700366647.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Greifswald", 
              "id": "https://www.grid.ac/institutes/grid.5603.0", 
              "name": [
                "Institute for Community Medicine, Ernst Moritz Arndt University Greifswald, 17475 Greifswald, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Becker", 
            "givenName": "Tim", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "23andMe (United States)", 
              "id": "https://www.grid.ac/institutes/grid.420283.f", 
              "name": [
                "23andMe Inc., Mountain View, California 94040, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hinds", 
            "givenName": "David A.", 
            "id": "sg:person.0767750151.59", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767750151.59"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany", 
                "Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "N\u00f6then", 
            "givenName": "Markus M.", 
            "id": "sg:person.01072523061.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072523061.22"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1111/j.1523-1747.2003.12615.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000379014", 
              "https://doi.org/10.1111/j.1523-1747.2003.12615.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1557988314538445", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002841718"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1557988314538445", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002841718"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0531-5565(02)00093-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003319123"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/bmj.327.7414.557", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005003882"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/exd.12785", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005093793"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1200/jco.2014.58.5588", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006014545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.714", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006029417", 
              "https://doi.org/10.1038/ng.714"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13545", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007797493", 
              "https://doi.org/10.1038/nature13545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13545", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007797493", 
              "https://doi.org/10.1038/nature13545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajhg.2011.02.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009526716"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2011.07.019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009625263"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2133.2011.10708.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011337846"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1016-1296a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011746138", 
              "https://doi.org/10.1038/ng1016-1296a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/09546639609086877", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012526911"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/exd.12024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013522372"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2756", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014945864", 
              "https://doi.org/10.1038/ng.2756"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/cshperspect.a013615", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015417965"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3406", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016405801", 
              "https://doi.org/10.1038/ng.3406"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1749-6632.1951.tb31971.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017345503"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddp003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017941032"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddp003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017941032"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/gerona/60.8.1077", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018110388"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ijcard.2014.07.079", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018111147"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaad.2010.12.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020213267"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1002746", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020950137"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(94)90276-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021453631"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/dev.20605", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021777869"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13595", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021916306", 
              "https://doi.org/10.1038/nature13595"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddn288", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022365148"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms6890", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022399023", 
              "https://doi.org/10.1038/ncomms6890"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4065/80.10.1316", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023604763"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jid.2016.03.032", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024384975"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/exd.12965", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024948104"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/dds361", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025754958"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1402862111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027205233"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/431425", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029130838"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1517/14728222.2014.922956", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029135639"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1262110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029707840"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.255", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030946270", 
              "https://doi.org/10.1038/ng.255"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1096/fj.04-2293fje", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031226208"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3570", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031947374", 
              "https://doi.org/10.1038/ng.3570"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrd4051", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032079011", 
              "https://doi.org/10.1038/nrd4051"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pmed.1001866", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032282372"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m212082200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032360442"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1046/j.1523-1747.1998.00427.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033141589", 
              "https://doi.org/10.1046/j.1523-1747.1998.00427.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.160", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034007928", 
              "https://doi.org/10.1038/ng.160"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2013.10.022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035625102"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pbio.1002002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035823906"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/bjd.12443", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035995744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1242/dev.108415", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036534475"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.jid.5700999", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036885431", 
              "https://doi.org/10.1038/sj.jid.5700999"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1200/jop.091087", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037036710"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/med.0b013e3282fe6ca9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038215123"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/med.0b013e3282fe6ca9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038215123"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/jid.2013.43", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038803530", 
              "https://doi.org/10.1038/jid.2013.43"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1000993", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038972494"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jpsychores.2016.04.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039493088"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2133.1992.tb00121.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039805940"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cca.2015.04.029", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039952542"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaad.2012.11.034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042040364"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jdermsci.2010.10.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043363260"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/bbrc.2001.6140", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044648263"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/aje/kwt096", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044652055"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddu150", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045399396"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molmed.2014.06.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046329923"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/bioinformatics/btq340", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047276303"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13679-014-0119-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047825320", 
              "https://doi.org/10.1007/s13679-014-0119-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/jid.2012.24", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049759127", 
              "https://doi.org/10.1038/jid.2012.24"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.228", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053468056", 
              "https://doi.org/10.1038/ng.228"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1000074", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053671247"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/er.2006-0020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064285862"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2013-2607", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064294492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem-20-10-1309", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064304746"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem-38-5-811", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064308440"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074641607", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2017-03-08", 
        "datePublishedReg": "2017-03-08", 
        "description": "Male-pattern baldness (MPB) is a common and highly heritable trait characterized by androgen-dependent, progressive hair loss from the scalp. Here, we carry out the largest GWAS meta-analysis of MPB to date, comprising 10,846 early-onset cases and 11,672 controls from eight independent cohorts. We identify 63 MPB-associated loci (P<5 \u00d7 10-8, METAL) of which 23 have not been reported previously. The 63 loci explain \u223c39% of the phenotypic variance in MPB and highlight several plausible candidate genes (FGF5, IRF4, DKK2) and pathways (melatonin signalling, adipogenesis) that are likely to be implicated in the key-pathophysiological features of MPB and may represent promising targets for the development of novel therapeutic options. The data provide molecular evidence that rather than being an isolated trait, MPB shares a substantial biological basis with numerous other human phenotypes and may deserve evaluation as an early prognostic marker, for example, for prostate cancer, sudden cardiac arrest and neurodegenerative disorders.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/ncomms14694", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.5138169", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1043282", 
            "issn": [
              "2041-1723"
            ], 
            "name": "Nature Communications", 
            "type": "Periodical"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "8"
          }
        ], 
        "name": "Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness", 
        "pagination": "14694", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "b84112966274080095de3eda24374dc094fa203638e2b3febdf852f5434837a4"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "28272467"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101528555"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/ncomms14694"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1084128922"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/ncomms14694", 
          "https://app.dimensions.ai/details/publication/pub.1084128922"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T16:51", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000573.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://www.nature.com/articles/ncomms14694"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ncomms14694'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ncomms14694'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ncomms14694'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ncomms14694'


     

    This table displays all metadata directly associated to this object as RDF triples.

    602 TRIPLES      21 PREDICATES      99 URIs      19 LITERALS      8 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/ncomms14694 schema:about anzsrc-for:11
    2 anzsrc-for:1112
    3 schema:author N3af992b904f849fea7e3e2811c2fff03
    4 schema:citation sg:pub.10.1007/s13679-014-0119-6
    5 sg:pub.10.1038/jid.2012.24
    6 sg:pub.10.1038/jid.2013.43
    7 sg:pub.10.1038/nature13545
    8 sg:pub.10.1038/nature13595
    9 sg:pub.10.1038/ncomms6890
    10 sg:pub.10.1038/ng.160
    11 sg:pub.10.1038/ng.228
    12 sg:pub.10.1038/ng.255
    13 sg:pub.10.1038/ng.2756
    14 sg:pub.10.1038/ng.3406
    15 sg:pub.10.1038/ng.3570
    16 sg:pub.10.1038/ng.714
    17 sg:pub.10.1038/ng1016-1296a
    18 sg:pub.10.1038/nrd4051
    19 sg:pub.10.1038/sj.jid.5700999
    20 sg:pub.10.1046/j.1523-1747.1998.00427.x
    21 sg:pub.10.1111/j.1523-1747.2003.12615.x
    22 https://app.dimensions.ai/details/publication/pub.1074641607
    23 https://doi.org/10.1002/dev.20605
    24 https://doi.org/10.1006/bbrc.2001.6140
    25 https://doi.org/10.1016/0092-8674(94)90276-3
    26 https://doi.org/10.1016/j.ajhg.2011.02.002
    27 https://doi.org/10.1016/j.cca.2015.04.029
    28 https://doi.org/10.1016/j.cell.2011.07.019
    29 https://doi.org/10.1016/j.cell.2013.10.022
    30 https://doi.org/10.1016/j.ijcard.2014.07.079
    31 https://doi.org/10.1016/j.jaad.2010.12.023
    32 https://doi.org/10.1016/j.jaad.2012.11.034
    33 https://doi.org/10.1016/j.jdermsci.2010.10.015
    34 https://doi.org/10.1016/j.jid.2016.03.032
    35 https://doi.org/10.1016/j.jpsychores.2016.04.005
    36 https://doi.org/10.1016/j.molmed.2014.06.002
    37 https://doi.org/10.1016/s0531-5565(02)00093-1
    38 https://doi.org/10.1073/pnas.1402862111
    39 https://doi.org/10.1074/jbc.m212082200
    40 https://doi.org/10.1086/431425
    41 https://doi.org/10.1093/aje/kwt096
    42 https://doi.org/10.1093/bioinformatics/btq340
    43 https://doi.org/10.1093/gerona/60.8.1077
    44 https://doi.org/10.1093/hmg/ddn288
    45 https://doi.org/10.1093/hmg/ddp003
    46 https://doi.org/10.1093/hmg/dds361
    47 https://doi.org/10.1093/hmg/ddu150
    48 https://doi.org/10.1096/fj.04-2293fje
    49 https://doi.org/10.1097/med.0b013e3282fe6ca9
    50 https://doi.org/10.1101/cshperspect.a013615
    51 https://doi.org/10.1111/bjd.12443
    52 https://doi.org/10.1111/exd.12024
    53 https://doi.org/10.1111/exd.12785
    54 https://doi.org/10.1111/exd.12965
    55 https://doi.org/10.1111/j.1365-2133.1992.tb00121.x
    56 https://doi.org/10.1111/j.1365-2133.2011.10708.x
    57 https://doi.org/10.1111/j.1749-6632.1951.tb31971.x
    58 https://doi.org/10.1126/science.1262110
    59 https://doi.org/10.1136/bmj.327.7414.557
    60 https://doi.org/10.1177/1557988314538445
    61 https://doi.org/10.1200/jco.2014.58.5588
    62 https://doi.org/10.1200/jop.091087
    63 https://doi.org/10.1210/er.2006-0020
    64 https://doi.org/10.1210/jc.2013-2607
    65 https://doi.org/10.1210/jcem-20-10-1309
    66 https://doi.org/10.1210/jcem-38-5-811
    67 https://doi.org/10.1242/dev.108415
    68 https://doi.org/10.1371/journal.pbio.1002002
    69 https://doi.org/10.1371/journal.pgen.1000074
    70 https://doi.org/10.1371/journal.pgen.1000993
    71 https://doi.org/10.1371/journal.pgen.1002746
    72 https://doi.org/10.1371/journal.pmed.1001866
    73 https://doi.org/10.1517/14728222.2014.922956
    74 https://doi.org/10.3109/09546639609086877
    75 https://doi.org/10.4065/80.10.1316
    76 schema:datePublished 2017-03-08
    77 schema:datePublishedReg 2017-03-08
    78 schema:description Male-pattern baldness (MPB) is a common and highly heritable trait characterized by androgen-dependent, progressive hair loss from the scalp. Here, we carry out the largest GWAS meta-analysis of MPB to date, comprising 10,846 early-onset cases and 11,672 controls from eight independent cohorts. We identify 63 MPB-associated loci (P&lt;5 × 10<sup>-8</sup>, METAL) of which 23 have not been reported previously. The 63 loci explain ∼39% of the phenotypic variance in MPB and highlight several plausible candidate genes (FGF5, IRF4, DKK2) and pathways (melatonin signalling, adipogenesis) that are likely to be implicated in the key-pathophysiological features of MPB and may represent promising targets for the development of novel therapeutic options. The data provide molecular evidence that rather than being an isolated trait, MPB shares a substantial biological basis with numerous other human phenotypes and may deserve evaluation as an early prognostic marker, for example, for prostate cancer, sudden cardiac arrest and neurodegenerative disorders.
    79 schema:genre research_article
    80 schema:inLanguage en
    81 schema:isAccessibleForFree true
    82 schema:isPartOf N3f5ac609e1674527a42d611a5d42093a
    83 sg:journal.1043282
    84 schema:name Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness
    85 schema:pagination 14694
    86 schema:productId N15e845ef00604386a937d602da71843b
    87 N3236b08d8a7e461fb022e2d361fdb41b
    88 Na7075e837de541f0ab533bd35801eccc
    89 Nb0263eb0c3b7408ab09c0ef3bf7d16fc
    90 Nc8f8dd496ee64a4d9a9be98cd70831a4
    91 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084128922
    92 https://doi.org/10.1038/ncomms14694
    93 schema:sdDatePublished 2019-04-10T16:51
    94 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    95 schema:sdPublisher N44a8fb021def4dc88938d22fe0ad69f6
    96 schema:url http://www.nature.com/articles/ncomms14694
    97 sgo:license sg:explorer/license/
    98 sgo:sdDataset articles
    99 rdf:type schema:ScholarlyArticle
    100 N053793d2b0ad49938cb8ddba85eb6c58 rdf:first sg:person.0700340034.34
    101 rdf:rest Ne695bee17a8647849210f32e31d30dce
    102 N108a134f770444c588c21298b855bc5e rdf:first sg:person.01021200171.47
    103 rdf:rest N11e9e1148c374ffb8a85611744c0ce46
    104 N11e9e1148c374ffb8a85611744c0ce46 rdf:first sg:person.01260346064.17
    105 rdf:rest Ne0d66e314e03458a9880dfb6454a03a6
    106 N15e845ef00604386a937d602da71843b schema:name dimensions_id
    107 schema:value pub.1084128922
    108 rdf:type schema:PropertyValue
    109 N168b44b33e30478f88694e9f5fc2536f rdf:first sg:person.014424006237.85
    110 rdf:rest Ndadcb21961264b9694ff39ac471726cd
    111 N1da0b31752cc409bb9c55f6cf2de7597 rdf:first sg:person.016023162734.90
    112 rdf:rest N7cf876fe7362408eb95b9c46c10ae010
    113 N1df33908781b474d886023f9cee130a3 schema:affiliation N615e0264227f4348b95c121990bce9d7
    114 schema:familyName Herold
    115 schema:givenName Christine
    116 rdf:type schema:Person
    117 N2e9e31f5e52040b897ec0a39a25acfa0 rdf:first N531410b15e6e40b6bdb504b98a07b411
    118 rdf:rest N4598bc81d3a04349a427721bde969933
    119 N3041fe315b26452682182f086019fec8 rdf:first N92a29c4acf964d6e90b4938ab9993498
    120 rdf:rest N562ab3e3657f482881acfd47e99d5ec1
    121 N3236b08d8a7e461fb022e2d361fdb41b schema:name readcube_id
    122 schema:value b84112966274080095de3eda24374dc094fa203638e2b3febdf852f5434837a4
    123 rdf:type schema:PropertyValue
    124 N349e0e484159422ba8587b3e637b962f rdf:first sg:person.016466407337.40
    125 rdf:rest N46e396621168400cae17e374bdac45a3
    126 N36a122579ed44f46abb066ce825e84a3 schema:affiliation https://www.grid.ac/institutes/grid.8515.9
    127 schema:familyName Waeber
    128 schema:givenName Gérard
    129 rdf:type schema:Person
    130 N3a4ae3f5c4ee4937b211ba236fdffd01 schema:name Centre for Clinical Epidemiology, Departments of Medicine, Genetics and Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, H3T 1E2 Canada
    131 rdf:type schema:Organization
    132 N3af992b904f849fea7e3e2811c2fff03 rdf:first sg:person.01122704751.01
    133 rdf:rest N8243166243bb428f9a72dfe273a23cc6
    134 N3f5ac609e1674527a42d611a5d42093a schema:volumeNumber 8
    135 rdf:type schema:PublicationVolume
    136 N44a8fb021def4dc88938d22fe0ad69f6 schema:name Springer Nature - SN SciGraph project
    137 rdf:type schema:Organization
    138 N44d70082a3f34d90a343cbb2a6bec3cc rdf:first N71cd5502e84e4d9ab42c032095c591b3
    139 rdf:rest Naffa2c79189148f29f9accb14c133604
    140 N4598bc81d3a04349a427721bde969933 rdf:first sg:person.012460064444.27
    141 rdf:rest Ndc346e95fef44bcf81fcc3ab10c5186a
    142 N46e396621168400cae17e374bdac45a3 rdf:first N799ea7eb8495446abb7a4fd144ec1448
    143 rdf:rest N4e723b6071a64b9f9bf1b097f1a73988
    144 N4e723b6071a64b9f9bf1b097f1a73988 rdf:first N36a122579ed44f46abb066ce825e84a3
    145 rdf:rest N168b44b33e30478f88694e9f5fc2536f
    146 N531410b15e6e40b6bdb504b98a07b411 schema:affiliation https://www.grid.ac/institutes/grid.418377.e
    147 schema:familyName Heng
    148 schema:givenName Xiu Ting
    149 rdf:type schema:Person
    150 N562ab3e3657f482881acfd47e99d5ec1 rdf:first sg:person.0634253750.76
    151 rdf:rest N96c2673621ba4a3892ea859f5885991d
    152 N615e0264227f4348b95c121990bce9d7 schema:name German Center for Neurodegenerative Disorders, 53175 Bonn, Germany
    153 rdf:type schema:Organization
    154 N71cd5502e84e4d9ab42c032095c591b3 schema:affiliation https://www.grid.ac/institutes/grid.5603.0
    155 schema:familyName Becker
    156 schema:givenName Tim
    157 rdf:type schema:Person
    158 N75a6220132ca49c999b6c862715f9895 rdf:first sg:person.0713541727.99
    159 rdf:rest Nd7d284591f80495daefecbe25b6dae96
    160 N799ea7eb8495446abb7a4fd144ec1448 schema:affiliation https://www.grid.ac/institutes/grid.4868.2
    161 schema:familyName Philpott
    162 schema:givenName Michael P.
    163 rdf:type schema:Person
    164 N7cf876fe7362408eb95b9c46c10ae010 rdf:first sg:person.01265671725.13
    165 rdf:rest Nbd13ca2359024ec6982ab69d9c8bd2b5
    166 N7e106b45bdc94b53b5cc5a841955b468 rdf:first sg:person.01163215763.76
    167 rdf:rest N75a6220132ca49c999b6c862715f9895
    168 N8243166243bb428f9a72dfe273a23cc6 rdf:first N1df33908781b474d886023f9cee130a3
    169 rdf:rest N7e106b45bdc94b53b5cc5a841955b468
    170 N913fcada8cc740409894045b4c5d8e6f schema:affiliation https://www.grid.ac/institutes/grid.8515.9
    171 schema:familyName Vollenweider
    172 schema:givenName Peter
    173 rdf:type schema:Person
    174 N92a29c4acf964d6e90b4938ab9993498 schema:affiliation https://www.grid.ac/institutes/grid.10388.32
    175 schema:familyName Hecker
    176 schema:givenName Julian
    177 rdf:type schema:Person
    178 N96c2673621ba4a3892ea859f5885991d rdf:first sg:person.0675736414.06
    179 rdf:rest Ne6f53db8369b4181abfaa8d52d739bb1
    180 Na46991450fd049a6b63172134dadb401 rdf:first sg:person.0770101774.48
    181 rdf:rest N2e9e31f5e52040b897ec0a39a25acfa0
    182 Na7075e837de541f0ab533bd35801eccc schema:name doi
    183 schema:value 10.1038/ncomms14694
    184 rdf:type schema:PropertyValue
    185 Na78f7bee91e4469e8ee00ef82cadc93a rdf:first sg:person.0740324166.54
    186 rdf:rest N349e0e484159422ba8587b3e637b962f
    187 Naffa2c79189148f29f9accb14c133604 rdf:first sg:person.0767750151.59
    188 rdf:rest Nfca80f74832c45bf9b282fbe221b207a
    189 Nb0263eb0c3b7408ab09c0ef3bf7d16fc schema:name pubmed_id
    190 schema:value 28272467
    191 rdf:type schema:PropertyValue
    192 Nbd13ca2359024ec6982ab69d9c8bd2b5 rdf:first sg:person.01322130132.87
    193 rdf:rest Nf16b7e4a9bc34460b92047768313a242
    194 Nc8f8dd496ee64a4d9a9be98cd70831a4 schema:name nlm_unique_id
    195 schema:value 101528555
    196 rdf:type schema:PropertyValue
    197 Ncbda60ea8fa4458db93acedc1db2b785 schema:affiliation N3a4ae3f5c4ee4937b211ba236fdffd01
    198 schema:familyName Li
    199 schema:givenName Rui
    200 rdf:type schema:Person
    201 Nce308504b54348bf89273792c7243a9d rdf:first sg:person.016033704317.28
    202 rdf:rest N1da0b31752cc409bb9c55f6cf2de7597
    203 Ncedfb3df312b4ea0af56444110e152a2 rdf:first sg:person.01223606626.04
    204 rdf:rest Neeb11816398d4687bc9ba6382a529e56
    205 Nd208961fa8914c8f853f4704071bd62a rdf:first sg:person.01347504124.22
    206 rdf:rest Nf044a1f14d544801b98b2abceaae1819
    207 Nd7d284591f80495daefecbe25b6dae96 rdf:first sg:person.01034633157.32
    208 rdf:rest N3041fe315b26452682182f086019fec8
    209 Ndadcb21961264b9694ff39ac471726cd rdf:first N913fcada8cc740409894045b4c5d8e6f
    210 rdf:rest Nce308504b54348bf89273792c7243a9d
    211 Ndc346e95fef44bcf81fcc3ab10c5186a rdf:first sg:person.0677446313.96
    212 rdf:rest Nd208961fa8914c8f853f4704071bd62a
    213 Ne0d66e314e03458a9880dfb6454a03a6 rdf:first sg:person.011746451777.08
    214 rdf:rest N053793d2b0ad49938cb8ddba85eb6c58
    215 Ne695bee17a8647849210f32e31d30dce rdf:first Ncbda60ea8fa4458db93acedc1db2b785
    216 rdf:rest Ncedfb3df312b4ea0af56444110e152a2
    217 Ne6f53db8369b4181abfaa8d52d739bb1 rdf:first sg:person.01367101560.30
    218 rdf:rest Na46991450fd049a6b63172134dadb401
    219 Neeb11816398d4687bc9ba6382a529e56 rdf:first sg:person.01222440332.93
    220 rdf:rest Na78f7bee91e4469e8ee00ef82cadc93a
    221 Nf044a1f14d544801b98b2abceaae1819 rdf:first sg:person.016317135745.67
    222 rdf:rest N108a134f770444c588c21298b855bc5e
    223 Nf16b7e4a9bc34460b92047768313a242 rdf:first sg:person.010700366647.17
    224 rdf:rest N44d70082a3f34d90a343cbb2a6bec3cc
    225 Nfca80f74832c45bf9b282fbe221b207a rdf:first sg:person.01072523061.22
    226 rdf:rest rdf:nil
    227 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    228 schema:name Medical and Health Sciences
    229 rdf:type schema:DefinedTerm
    230 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    231 schema:name Oncology and Carcinogenesis
    232 rdf:type schema:DefinedTerm
    233 sg:grant.5138169 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms14694
    234 rdf:type schema:MonetaryGrant
    235 sg:journal.1043282 schema:issn 2041-1723
    236 schema:name Nature Communications
    237 rdf:type schema:Periodical
    238 sg:person.01021200171.47 schema:affiliation https://www.grid.ac/institutes/grid.10417.33
    239 schema:familyName Galesloot
    240 schema:givenName Tessel E.
    241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021200171.47
    242 rdf:type schema:Person
    243 sg:person.01034633157.32 schema:affiliation https://www.grid.ac/institutes/grid.1024.7
    244 schema:familyName Nyholt
    245 schema:givenName Dale R.
    246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034633157.32
    247 rdf:type schema:Person
    248 sg:person.010700366647.17 schema:affiliation https://www.grid.ac/institutes/grid.1049.c
    249 schema:familyName Martin
    250 schema:givenName Nicholas G.
    251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010700366647.17
    252 rdf:type schema:Person
    253 sg:person.01072523061.22 schema:affiliation https://www.grid.ac/institutes/grid.10388.32
    254 schema:familyName Nöthen
    255 schema:givenName Markus M.
    256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072523061.22
    257 rdf:type schema:Person
    258 sg:person.01122704751.01 schema:affiliation https://www.grid.ac/institutes/grid.10388.32
    259 schema:familyName Heilmann-Heimbach
    260 schema:givenName Stefanie
    261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01122704751.01
    262 rdf:type schema:Person
    263 sg:person.01163215763.76 schema:affiliation https://www.grid.ac/institutes/grid.10388.32
    264 schema:familyName Hochfeld
    265 schema:givenName Lara M.
    266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163215763.76
    267 rdf:type schema:Person
    268 sg:person.011746451777.08 schema:affiliation https://www.grid.ac/institutes/grid.10388.32
    269 schema:familyName Anhalt
    270 schema:givenName Thomas
    271 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011746451777.08
    272 rdf:type schema:Person
    273 sg:person.01222440332.93 schema:affiliation https://www.grid.ac/institutes/grid.15823.3d
    274 schema:familyName Papanikolaou
    275 schema:givenName George
    276 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222440332.93
    277 rdf:type schema:Person
    278 sg:person.01223606626.04 schema:affiliation https://www.grid.ac/institutes/grid.4868.2
    279 schema:familyName Kanoni
    280 schema:givenName Stavroula
    281 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223606626.04
    282 rdf:type schema:Person
    283 sg:person.012460064444.27 schema:affiliation https://www.grid.ac/institutes/grid.418377.e
    284 schema:familyName del Rosario
    285 schema:givenName Ricardo C. -H.
    286 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012460064444.27
    287 rdf:type schema:Person
    288 sg:person.01260346064.17 schema:affiliation https://www.grid.ac/institutes/grid.5718.b
    289 schema:familyName Moebus
    290 schema:givenName Susanne
    291 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260346064.17
    292 rdf:type schema:Person
    293 sg:person.01265671725.13 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
    294 schema:familyName Richards
    295 schema:givenName J. Brent
    296 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265671725.13
    297 rdf:type schema:Person
    298 sg:person.01322130132.87 schema:affiliation https://www.grid.ac/institutes/grid.6190.e
    299 schema:familyName Nothnagel
    300 schema:givenName Michael
    301 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322130132.87
    302 rdf:type schema:Person
    303 sg:person.01347504124.22 schema:affiliation https://www.grid.ac/institutes/grid.5379.8
    304 schema:familyName Paus
    305 schema:givenName Ralf
    306 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347504124.22
    307 rdf:type schema:Person
    308 sg:person.01367101560.30 schema:affiliation https://www.grid.ac/institutes/grid.5718.b
    309 schema:familyName Pechlivanis
    310 schema:givenName Sonali
    311 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367101560.30
    312 rdf:type schema:Person
    313 sg:person.014424006237.85 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
    314 schema:familyName Spector
    315 schema:givenName Tim D.
    316 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014424006237.85
    317 rdf:type schema:Person
    318 sg:person.016023162734.90 schema:affiliation https://www.grid.ac/institutes/grid.15823.3d
    319 schema:familyName Dedoussis
    320 schema:givenName George
    321 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016023162734.90
    322 rdf:type schema:Person
    323 sg:person.016033704317.28 schema:affiliation https://www.grid.ac/institutes/grid.10417.33
    324 schema:familyName Kiemeney
    325 schema:givenName Lambertus A. L. M.
    326 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016033704317.28
    327 rdf:type schema:Person
    328 sg:person.016317135745.67 schema:affiliation https://www.grid.ac/institutes/grid.419765.8
    329 schema:familyName Rueedi
    330 schema:givenName Rico
    331 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016317135745.67
    332 rdf:type schema:Person
    333 sg:person.016466407337.40 schema:affiliation https://www.grid.ac/institutes/grid.412125.1
    334 schema:familyName Deloukas
    335 schema:givenName Panos
    336 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016466407337.40
    337 rdf:type schema:Person
    338 sg:person.0634253750.76 schema:affiliation https://www.grid.ac/institutes/grid.418377.e
    339 schema:familyName Javed
    340 schema:givenName Asif
    341 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634253750.76
    342 rdf:type schema:Person
    343 sg:person.0675736414.06 schema:affiliation https://www.grid.ac/institutes/grid.418377.e
    344 schema:familyName Chew
    345 schema:givenName Elaine G. Y.
    346 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675736414.06
    347 rdf:type schema:Person
    348 sg:person.0677446313.96 schema:affiliation https://www.grid.ac/institutes/grid.10388.32
    349 schema:familyName Fier
    350 schema:givenName Heide L.
    351 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677446313.96
    352 rdf:type schema:Person
    353 sg:person.0700340034.34 schema:affiliation https://www.grid.ac/institutes/grid.418377.e
    354 schema:familyName Prabhakar
    355 schema:givenName Shyam
    356 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700340034.34
    357 rdf:type schema:Person
    358 sg:person.0713541727.99 schema:affiliation https://www.grid.ac/institutes/grid.461816.c
    359 schema:familyName Hillmer
    360 schema:givenName Axel M.
    361 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713541727.99
    362 rdf:type schema:Person
    363 sg:person.0740324166.54 schema:affiliation https://www.grid.ac/institutes/grid.482968.9
    364 schema:familyName Kutalik
    365 schema:givenName Zoltán
    366 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0740324166.54
    367 rdf:type schema:Person
    368 sg:person.0767750151.59 schema:affiliation https://www.grid.ac/institutes/grid.420283.f
    369 schema:familyName Hinds
    370 schema:givenName David A.
    371 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767750151.59
    372 rdf:type schema:Person
    373 sg:person.0770101774.48 schema:affiliation https://www.grid.ac/institutes/grid.6190.e
    374 schema:familyName Drichel
    375 schema:givenName Dmitriy
    376 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0770101774.48
    377 rdf:type schema:Person
    378 sg:pub.10.1007/s13679-014-0119-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047825320
    379 https://doi.org/10.1007/s13679-014-0119-6
    380 rdf:type schema:CreativeWork
    381 sg:pub.10.1038/jid.2012.24 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049759127
    382 https://doi.org/10.1038/jid.2012.24
    383 rdf:type schema:CreativeWork
    384 sg:pub.10.1038/jid.2013.43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038803530
    385 https://doi.org/10.1038/jid.2013.43
    386 rdf:type schema:CreativeWork
    387 sg:pub.10.1038/nature13545 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007797493
    388 https://doi.org/10.1038/nature13545
    389 rdf:type schema:CreativeWork
    390 sg:pub.10.1038/nature13595 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021916306
    391 https://doi.org/10.1038/nature13595
    392 rdf:type schema:CreativeWork
    393 sg:pub.10.1038/ncomms6890 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022399023
    394 https://doi.org/10.1038/ncomms6890
    395 rdf:type schema:CreativeWork
    396 sg:pub.10.1038/ng.160 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034007928
    397 https://doi.org/10.1038/ng.160
    398 rdf:type schema:CreativeWork
    399 sg:pub.10.1038/ng.228 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053468056
    400 https://doi.org/10.1038/ng.228
    401 rdf:type schema:CreativeWork
    402 sg:pub.10.1038/ng.255 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030946270
    403 https://doi.org/10.1038/ng.255
    404 rdf:type schema:CreativeWork
    405 sg:pub.10.1038/ng.2756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014945864
    406 https://doi.org/10.1038/ng.2756
    407 rdf:type schema:CreativeWork
    408 sg:pub.10.1038/ng.3406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016405801
    409 https://doi.org/10.1038/ng.3406
    410 rdf:type schema:CreativeWork
    411 sg:pub.10.1038/ng.3570 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031947374
    412 https://doi.org/10.1038/ng.3570
    413 rdf:type schema:CreativeWork
    414 sg:pub.10.1038/ng.714 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006029417
    415 https://doi.org/10.1038/ng.714
    416 rdf:type schema:CreativeWork
    417 sg:pub.10.1038/ng1016-1296a schema:sameAs https://app.dimensions.ai/details/publication/pub.1011746138
    418 https://doi.org/10.1038/ng1016-1296a
    419 rdf:type schema:CreativeWork
    420 sg:pub.10.1038/nrd4051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032079011
    421 https://doi.org/10.1038/nrd4051
    422 rdf:type schema:CreativeWork
    423 sg:pub.10.1038/sj.jid.5700999 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036885431
    424 https://doi.org/10.1038/sj.jid.5700999
    425 rdf:type schema:CreativeWork
    426 sg:pub.10.1046/j.1523-1747.1998.00427.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033141589
    427 https://doi.org/10.1046/j.1523-1747.1998.00427.x
    428 rdf:type schema:CreativeWork
    429 sg:pub.10.1111/j.1523-1747.2003.12615.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1000379014
    430 https://doi.org/10.1111/j.1523-1747.2003.12615.x
    431 rdf:type schema:CreativeWork
    432 https://app.dimensions.ai/details/publication/pub.1074641607 schema:CreativeWork
    433 https://doi.org/10.1002/dev.20605 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021777869
    434 rdf:type schema:CreativeWork
    435 https://doi.org/10.1006/bbrc.2001.6140 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044648263
    436 rdf:type schema:CreativeWork
    437 https://doi.org/10.1016/0092-8674(94)90276-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021453631
    438 rdf:type schema:CreativeWork
    439 https://doi.org/10.1016/j.ajhg.2011.02.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009526716
    440 rdf:type schema:CreativeWork
    441 https://doi.org/10.1016/j.cca.2015.04.029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039952542
    442 rdf:type schema:CreativeWork
    443 https://doi.org/10.1016/j.cell.2011.07.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009625263
    444 rdf:type schema:CreativeWork
    445 https://doi.org/10.1016/j.cell.2013.10.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035625102
    446 rdf:type schema:CreativeWork
    447 https://doi.org/10.1016/j.ijcard.2014.07.079 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018111147
    448 rdf:type schema:CreativeWork
    449 https://doi.org/10.1016/j.jaad.2010.12.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020213267
    450 rdf:type schema:CreativeWork
    451 https://doi.org/10.1016/j.jaad.2012.11.034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042040364
    452 rdf:type schema:CreativeWork
    453 https://doi.org/10.1016/j.jdermsci.2010.10.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043363260
    454 rdf:type schema:CreativeWork
    455 https://doi.org/10.1016/j.jid.2016.03.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024384975
    456 rdf:type schema:CreativeWork
    457 https://doi.org/10.1016/j.jpsychores.2016.04.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039493088
    458 rdf:type schema:CreativeWork
    459 https://doi.org/10.1016/j.molmed.2014.06.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046329923
    460 rdf:type schema:CreativeWork
    461 https://doi.org/10.1016/s0531-5565(02)00093-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003319123
    462 rdf:type schema:CreativeWork
    463 https://doi.org/10.1073/pnas.1402862111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027205233
    464 rdf:type schema:CreativeWork
    465 https://doi.org/10.1074/jbc.m212082200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032360442
    466 rdf:type schema:CreativeWork
    467 https://doi.org/10.1086/431425 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029130838
    468 rdf:type schema:CreativeWork
    469 https://doi.org/10.1093/aje/kwt096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044652055
    470 rdf:type schema:CreativeWork
    471 https://doi.org/10.1093/bioinformatics/btq340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047276303
    472 rdf:type schema:CreativeWork
    473 https://doi.org/10.1093/gerona/60.8.1077 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018110388
    474 rdf:type schema:CreativeWork
    475 https://doi.org/10.1093/hmg/ddn288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022365148
    476 rdf:type schema:CreativeWork
    477 https://doi.org/10.1093/hmg/ddp003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017941032
    478 rdf:type schema:CreativeWork
    479 https://doi.org/10.1093/hmg/dds361 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025754958
    480 rdf:type schema:CreativeWork
    481 https://doi.org/10.1093/hmg/ddu150 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045399396
    482 rdf:type schema:CreativeWork
    483 https://doi.org/10.1096/fj.04-2293fje schema:sameAs https://app.dimensions.ai/details/publication/pub.1031226208
    484 rdf:type schema:CreativeWork
    485 https://doi.org/10.1097/med.0b013e3282fe6ca9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038215123
    486 rdf:type schema:CreativeWork
    487 https://doi.org/10.1101/cshperspect.a013615 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015417965
    488 rdf:type schema:CreativeWork
    489 https://doi.org/10.1111/bjd.12443 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035995744
    490 rdf:type schema:CreativeWork
    491 https://doi.org/10.1111/exd.12024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013522372
    492 rdf:type schema:CreativeWork
    493 https://doi.org/10.1111/exd.12785 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005093793
    494 rdf:type schema:CreativeWork
    495 https://doi.org/10.1111/exd.12965 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024948104
    496 rdf:type schema:CreativeWork
    497 https://doi.org/10.1111/j.1365-2133.1992.tb00121.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039805940
    498 rdf:type schema:CreativeWork
    499 https://doi.org/10.1111/j.1365-2133.2011.10708.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1011337846
    500 rdf:type schema:CreativeWork
    501 https://doi.org/10.1111/j.1749-6632.1951.tb31971.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1017345503
    502 rdf:type schema:CreativeWork
    503 https://doi.org/10.1126/science.1262110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029707840
    504 rdf:type schema:CreativeWork
    505 https://doi.org/10.1136/bmj.327.7414.557 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005003882
    506 rdf:type schema:CreativeWork
    507 https://doi.org/10.1177/1557988314538445 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002841718
    508 rdf:type schema:CreativeWork
    509 https://doi.org/10.1200/jco.2014.58.5588 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006014545
    510 rdf:type schema:CreativeWork
    511 https://doi.org/10.1200/jop.091087 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037036710
    512 rdf:type schema:CreativeWork
    513 https://doi.org/10.1210/er.2006-0020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064285862
    514 rdf:type schema:CreativeWork
    515 https://doi.org/10.1210/jc.2013-2607 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064294492
    516 rdf:type schema:CreativeWork
    517 https://doi.org/10.1210/jcem-20-10-1309 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064304746
    518 rdf:type schema:CreativeWork
    519 https://doi.org/10.1210/jcem-38-5-811 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064308440
    520 rdf:type schema:CreativeWork
    521 https://doi.org/10.1242/dev.108415 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036534475
    522 rdf:type schema:CreativeWork
    523 https://doi.org/10.1371/journal.pbio.1002002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035823906
    524 rdf:type schema:CreativeWork
    525 https://doi.org/10.1371/journal.pgen.1000074 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053671247
    526 rdf:type schema:CreativeWork
    527 https://doi.org/10.1371/journal.pgen.1000993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038972494
    528 rdf:type schema:CreativeWork
    529 https://doi.org/10.1371/journal.pgen.1002746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020950137
    530 rdf:type schema:CreativeWork
    531 https://doi.org/10.1371/journal.pmed.1001866 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032282372
    532 rdf:type schema:CreativeWork
    533 https://doi.org/10.1517/14728222.2014.922956 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029135639
    534 rdf:type schema:CreativeWork
    535 https://doi.org/10.3109/09546639609086877 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012526911
    536 rdf:type schema:CreativeWork
    537 https://doi.org/10.4065/80.10.1316 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023604763
    538 rdf:type schema:CreativeWork
    539 https://www.grid.ac/institutes/grid.1024.7 schema:alternateName Queensland University of Technology
    540 schema:name Institute of Health and Biomedical Innovation, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, Australia
    541 rdf:type schema:Organization
    542 https://www.grid.ac/institutes/grid.10388.32 schema:alternateName University of Bonn
    543 schema:name Department of Biostatistics, Harvard School T.H. Chan of Public Health, Boston, Massachusetts 02115, USA
    544 Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany
    545 Institute of Genomic Mathematics, University of Bonn, 53127 Bonn, Germany
    546 Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany
    547 rdf:type schema:Organization
    548 https://www.grid.ac/institutes/grid.10417.33 schema:alternateName Radboud University Nijmegen Medical Centre
    549 schema:name Radboud Institute for Health Sciences, Department for Health Evidence, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands
    550 rdf:type schema:Organization
    551 https://www.grid.ac/institutes/grid.1049.c schema:alternateName QIMR Berghofer Medical Research Institute
    552 schema:name QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia
    553 rdf:type schema:Organization
    554 https://www.grid.ac/institutes/grid.13097.3c schema:alternateName King's College London
    555 schema:name Centre for Clinical Epidemiology, Departments of Medicine, Genetics and Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, H3T 1E2 Canada
    556 Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK
    557 rdf:type schema:Organization
    558 https://www.grid.ac/institutes/grid.15823.3d schema:alternateName Harokopio University
    559 schema:name School of Health Sciences and Education, Department of Nutrition and Dietetics, Harokopio University, Attica, 17671 Kallithea, Greece
    560 rdf:type schema:Organization
    561 https://www.grid.ac/institutes/grid.412125.1 schema:alternateName King Abdulaziz University
    562 schema:name Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 21589, Saudi Arabia
    563 William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK
    564 rdf:type schema:Organization
    565 https://www.grid.ac/institutes/grid.418377.e schema:alternateName Genome Institute of Singapore
    566 schema:name Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore
    567 Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore
    568 rdf:type schema:Organization
    569 https://www.grid.ac/institutes/grid.419765.8 schema:alternateName Swiss Institute of Bioinformatics
    570 schema:name Department of Computational Biology, University of Lausanne, 1011 Lausanne, Switzerland
    571 Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland
    572 rdf:type schema:Organization
    573 https://www.grid.ac/institutes/grid.420283.f schema:alternateName 23andMe (United States)
    574 schema:name 23andMe Inc., Mountain View, California 94040, USA
    575 rdf:type schema:Organization
    576 https://www.grid.ac/institutes/grid.461816.c schema:alternateName Translational Oncology
    577 schema:name Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore
    578 TRON-Translational Oncology at the University Medical Center of Johannes Gutenberg University, TRON gGmbH, 55131 Mainz, Germany
    579 rdf:type schema:Organization
    580 https://www.grid.ac/institutes/grid.482968.9 schema:alternateName Institute of Social and Preventive Medicine
    581 schema:name Institute of Social and Preventive Medicine, University Hospital of Lausanne, 1010 Lausanne, Switzerland
    582 Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland
    583 rdf:type schema:Organization
    584 https://www.grid.ac/institutes/grid.4868.2 schema:alternateName Queen Mary University of London
    585 schema:name Centre for Cell Biology and Cutaneous Research Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK
    586 William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK
    587 rdf:type schema:Organization
    588 https://www.grid.ac/institutes/grid.5379.8 schema:alternateName University of Manchester
    589 schema:name Dermatology Research Centre, Institute of Inflammation and Repair, University of Manchester, Manchester M13 9PL, UK
    590 rdf:type schema:Organization
    591 https://www.grid.ac/institutes/grid.5603.0 schema:alternateName University of Greifswald
    592 schema:name Institute for Community Medicine, Ernst Moritz Arndt University Greifswald, 17475 Greifswald, Germany
    593 rdf:type schema:Organization
    594 https://www.grid.ac/institutes/grid.5718.b schema:alternateName University of Duisburg-Essen
    595 schema:name Institute of Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-Essen, 45122 Essen, Germany
    596 rdf:type schema:Organization
    597 https://www.grid.ac/institutes/grid.6190.e schema:alternateName University of Cologne
    598 schema:name Cologne Center for Genomics, University of Cologne, 50931 Cologne, Germany
    599 rdf:type schema:Organization
    600 https://www.grid.ac/institutes/grid.8515.9 schema:alternateName University Hospital of Lausanne
    601 schema:name Department of Internal Medicine, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland
    602 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...