MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

Elizabeth J. Perlman, Samantha Gadd, Stefan T. Arold, Anand Radhakrishnan, Daniela S. Gerhard, Lawrence Jennings, Vicki Huff, Jaime M. Guidry Auvil, Tanja M. Davidsen, Jeffrey S. Dome, Daoud Meerzaman, Chih Hao Hsu, Cu Nguyen, James Anderson, Yussanne Ma, Andrew J. Mungall, Richard A. Moore, Marco A. Marra, Charles G. Mullighan, Jing Ma, David A. Wheeler, Oliver A. Hampton, Julie M. Gastier-Foster, Nicole Ross, Malcolm A. Smith

ABSTRACT

Wilms tumour is an embryonal tumour of childhood that closely resembles the developing kidney. Genomic changes responsible for the development of the majority of Wilms tumours remain largely unknown. Here we identify recurrent mutations within Wilms tumours that involve the highly conserved YEATS domain of MLLT1 (ENL), a gene known to be involved in transcriptional elongation during early development. The mutant MLLT1 protein shows altered binding to acetylated histone tails. Moreover, MLLT1-mutant tumours show an increase in MYC gene expression and HOX dysregulation. Patients with MLLT1-mutant tumours present at a younger age and have a high prevalence of precursor intralobar nephrogenic rests. These data support a model whereby activating MLLT1 mutations early in renal development result in the development of Wilms tumour. More... »

PAGES

10013

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncomms10013

DOI

http://dx.doi.org/10.1038/ncomms10013

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036403844

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26635203


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Histones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nuclear Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Binding", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Structure, Tertiary", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins c-myc", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Wilms Tumor", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Lurie Children's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413808.6", 
          "name": [
            "Department of Pathology, Ann & Robert H. Lurie Children\u2019s Hospital of Chicago, Northwestern University\u2019s Feinberg School of Medicine, 225 E. Chicago Ave, Chicago, Illinosis 60611, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Perlman", 
        "givenName": "Elizabeth J.", 
        "id": "sg:person.01361007034.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361007034.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Lurie Children's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413808.6", 
          "name": [
            "Department of Pathology, Ann & Robert H. Lurie Children\u2019s Hospital of Chicago, Northwestern University\u2019s Feinberg School of Medicine, 225 E. Chicago Ave, Chicago, Illinosis 60611, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gadd", 
        "givenName": "Samantha", 
        "id": "sg:person.0673716355.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673716355.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King Abdullah University of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.45672.32", 
          "name": [
            "King Abdullah University of Science and Technology, Department of Biochemistry and Molecular Biology, Division of Biological and Environmental Sciences and Engineering, Computational Bioscience Research Center, Thuwal 23955, Saudi Arabia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Arold", 
        "givenName": "Stefan T.", 
        "id": "sg:person.0706310437.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706310437.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King Abdullah University of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.45672.32", 
          "name": [
            "King Abdullah University of Science and Technology, Department of Biochemistry and Molecular Biology, Division of Biological and Environmental Sciences and Engineering, Computational Bioscience Research Center, Thuwal 23955, Saudi Arabia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Radhakrishnan", 
        "givenName": "Anand", 
        "id": "sg:person.01047057656.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047057656.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.48336.3a", 
          "name": [
            "Office of Cancer Genomics, National Cancer Institute, 31 Center Drive, Bethesda, Maryland 20892, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gerhard", 
        "givenName": "Daniela S.", 
        "id": "sg:person.014015600757.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014015600757.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Lurie Children's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413808.6", 
          "name": [
            "Department of Pathology, Ann & Robert H. Lurie Children\u2019s Hospital of Chicago, Northwestern University\u2019s Feinberg School of Medicine, 225 E. Chicago Ave, Chicago, Illinosis 60611, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jennings", 
        "givenName": "Lawrence", 
        "id": "sg:person.01010144755.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010144755.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Genetics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas 77030, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Huff", 
        "givenName": "Vicki", 
        "id": "sg:person.0753532033.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753532033.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.48336.3a", 
          "name": [
            "Office of Cancer Genomics, National Cancer Institute, 31 Center Drive, Bethesda, Maryland 20892, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Auvil", 
        "givenName": "Jaime M. Guidry", 
        "id": "sg:person.01030532166.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030532166.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.48336.3a", 
          "name": [
            "Office of Cancer Genomics, National Cancer Institute, 31 Center Drive, Bethesda, Maryland 20892, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Davidsen", 
        "givenName": "Tanja M.", 
        "id": "sg:person.0716572051.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716572051.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Children\u2019s National Health System", 
          "id": "https://www.grid.ac/institutes/grid.239560.b", 
          "name": [
            "Department of Pediatrics, Division of Pediatric Hematology/Oncology, Children\u2019s National Medical Center, 111 Michigan Avenue, NW, Washington DC 20010, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dome", 
        "givenName": "Jeffrey S.", 
        "id": "sg:person.0632564577.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632564577.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institutes of Health", 
          "id": "https://www.grid.ac/institutes/grid.94365.3d", 
          "name": [
            "Center for Biomedical Informatics and Information Technology, National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Bethesda, Maryland 20892, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Meerzaman", 
        "givenName": "Daoud", 
        "id": "sg:person.013732223267.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013732223267.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institutes of Health", 
          "id": "https://www.grid.ac/institutes/grid.94365.3d", 
          "name": [
            "Center for Biomedical Informatics and Information Technology, National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Bethesda, Maryland 20892, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hsu", 
        "givenName": "Chih Hao", 
        "id": "sg:person.01036437235.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036437235.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institutes of Health", 
          "id": "https://www.grid.ac/institutes/grid.94365.3d", 
          "name": [
            "Center for Biomedical Informatics and Information Technology, National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Bethesda, Maryland 20892, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nguyen", 
        "givenName": "Cu", 
        "id": "sg:person.01361404112.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361404112.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Frontier Science & Technology Research Foundation", 
          "id": "https://www.grid.ac/institutes/grid.421586.c", 
          "name": [
            "Frontier Science and Technology Research Foundation, 505 S. Rosa Rd #100, Madison, Wisconsin 53719, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Anderson", 
        "givenName": "James", 
        "id": "sg:person.07540064457.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07540064457.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "BC Cancer Agency", 
          "id": "https://www.grid.ac/institutes/grid.248762.d", 
          "name": [
            "Canada\u2019s Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada V5Z 4S6"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ma", 
        "givenName": "Yussanne", 
        "id": "sg:person.01276051237.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276051237.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "BC Cancer Agency", 
          "id": "https://www.grid.ac/institutes/grid.248762.d", 
          "name": [
            "Canada\u2019s Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada V5Z 4S6"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mungall", 
        "givenName": "Andrew J.", 
        "id": "sg:person.0627357425.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627357425.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "BC Cancer Agency", 
          "id": "https://www.grid.ac/institutes/grid.248762.d", 
          "name": [
            "Canada\u2019s Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada V5Z 4S6"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moore", 
        "givenName": "Richard A.", 
        "id": "sg:person.0732441037.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732441037.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "BC Cancer Agency", 
          "id": "https://www.grid.ac/institutes/grid.248762.d", 
          "name": [
            "Canada\u2019s Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada V5Z 4S6"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Marra", 
        "givenName": "Marco A.", 
        "id": "sg:person.01150455763.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150455763.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "St. Jude Children's Research Hospital", 
          "id": "https://www.grid.ac/institutes/grid.240871.8", 
          "name": [
            "Department of Pathology, St Jude Children\u2019s Research Hospital, 262 Danny Thomas Place, Mail Stop 342, Memphis, Tennessee 38105, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mullighan", 
        "givenName": "Charles G.", 
        "id": "sg:person.0671073025.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671073025.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "St. Jude Children's Research Hospital", 
          "id": "https://www.grid.ac/institutes/grid.240871.8", 
          "name": [
            "Department of Pathology, St Jude Children\u2019s Research Hospital, 262 Danny Thomas Place, Mail Stop 342, Memphis, Tennessee 38105, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ma", 
        "givenName": "Jing", 
        "id": "sg:person.0640762041.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640762041.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, Ohio 43205, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wheeler", 
        "givenName": "David A.", 
        "id": "sg:person.0764131534.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764131534.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, Ohio 43205, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hampton", 
        "givenName": "Oliver A.", 
        "id": "sg:person.01117110520.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117110520.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA", 
            "Departments of Pathology and Pediatrics, Ohio State University College of Medicine, 700 Children's Drive, Columbus, Ohio 43205, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gastier-Foster", 
        "givenName": "Julie M.", 
        "id": "sg:person.01146630513.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146630513.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Baylor College of Medicine", 
          "id": "https://www.grid.ac/institutes/grid.39382.33", 
          "name": [
            "Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ross", 
        "givenName": "Nicole", 
        "id": "sg:person.0621523641.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621523641.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Cancer Institute", 
          "id": "https://www.grid.ac/institutes/grid.48336.3a", 
          "name": [
            "Cancer Therapy Evaluation Program, National Cancer Institute, 9609 Medical Center Drive, RM 5-W414, MSC 9737, Bethesda, Maryland 20892, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Smith", 
        "givenName": "Malcolm A.", 
        "id": "sg:person.01220513165.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220513165.63"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/ncomms5398", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000289049", 
          "https://doi.org/10.1038/ncomms5398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molcel.2010.01.026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000655450"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature11632", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000661742", 
          "https://doi.org/10.1038/nature11632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0308531101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001366510"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.091062498", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001631710"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0594-91", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001746104", 
          "https://doi.org/10.1038/ng0594-91"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.2059211", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002057650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/hmg/ddl444", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003197230"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1472-6807-9-35", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003576798", 
          "https://doi.org/10.1186/1472-6807-9-35"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molcel.2006.06.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005228370"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1107107108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005396588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(02)01084-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005479566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkq929", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005486377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccr.2009.12.040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005535275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/29.1.308", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005817660"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth0410-248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007489634", 
          "https://doi.org/10.1038/nmeth0410-248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth0410-248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007489634", 
          "https://doi.org/10.1038/nmeth0410-248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1593/neo.12714", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008209714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m601903200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009441389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/gm415", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011030823", 
          "https://doi.org/10.1186/gm415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fgene.2012.00270", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012225562"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1210582", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013831372", 
          "https://doi.org/10.1038/sj.onc.1210582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/15513819009067094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014227988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.28239", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014261208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(197805)41:5<1937::aid-cncr2820410538>3.0.co;2-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014465903"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pgen.1000190", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014802806"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1181498", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014947319"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1181498", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014947319"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/gm461", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015036269", 
          "https://doi.org/10.1186/gm461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btr032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017115352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2005.01.2799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017832430"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10398", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018204822", 
          "https://doi.org/10.1038/nature10398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2010.31.5192", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018710861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019623099", 
          "https://doi.org/10.1038/ng1048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019623099", 
          "https://doi.org/10.1038/ng1048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1208699", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019968921", 
          "https://doi.org/10.1038/sj.onc.1208699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1208699", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019968921", 
          "https://doi.org/10.1038/sj.onc.1208699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0061055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020348126"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jmg.2006.041723", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020542404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3324/haematol.2008.002436", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025448661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccell.2015.01.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026617605"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2007-05-090514", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027305941"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pbio.1000249", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028688446"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.02076-07", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028755884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029739875", 
          "https://doi.org/10.1038/nature09819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029739875", 
          "https://doi.org/10.1038/nature09819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2014.09.049", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031055580"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/bti770", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031081661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m109.017442", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032954243"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034028024", 
          "https://doi.org/10.1038/nrc1696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034028024", 
          "https://doi.org/10.1038/nrc1696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034028024", 
          "https://doi.org/10.1038/nrc1696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc2253", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035045408", 
          "https://doi.org/10.1038/nrc2253"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btn624", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037879241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm3417", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037885873", 
          "https://doi.org/10.1038/nrm3417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pbc.24604", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037998819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bcmd.2002.0525", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038939572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-013-0564-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040622823", 
          "https://doi.org/10.1007/s12032-013-0564-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0046688", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043907803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ydbio.2012.05.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044574523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2009.02.055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044969059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pros.10185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045017388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.00182-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045722449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btq330", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047117020"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m112.409102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048562624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2007.05.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051644950"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/o08-111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052666969"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/biomet/73.1.1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059419563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/epi.5.7.12856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072303045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074735182", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5347(17)38582-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077655553"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-12", 
    "datePublishedReg": "2015-12-01", 
    "description": "Wilms tumour is an embryonal tumour of childhood that closely resembles the developing kidney. Genomic changes responsible for the development of the majority of Wilms tumours remain largely unknown. Here we identify recurrent mutations within Wilms tumours that involve the highly conserved YEATS domain of MLLT1 (ENL), a gene known to be involved in transcriptional elongation during early development. The mutant MLLT1 protein shows altered binding to acetylated histone tails. Moreover, MLLT1-mutant tumours show an increase in MYC gene expression and HOX dysregulation. Patients with MLLT1-mutant tumours present at a younger age and have a high prevalence of precursor intralobar nephrogenic rests. These data support a model whereby activating MLLT1 mutations early in renal development result in the development of Wilms tumour. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ncomms10013", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2688942", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2693529", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2696311", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2438833", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2343593", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2693700", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1043282", 
        "issn": [
          "2041-1723"
        ], 
        "name": "Nature Communications", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "name": "MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours", 
    "pagination": "10013", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ad6a39606c4992d1443639df21b0e219a492a111e3e2c12b4dde7f5e6cca06e2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26635203"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101528555"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ncomms10013"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036403844"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ncomms10013", 
      "https://app.dimensions.ai/details/publication/pub.1036403844"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T00:23", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000550.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/ncomms10013"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ncomms10013'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ncomms10013'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ncomms10013'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ncomms10013'


 

This table displays all metadata directly associated to this object as RDF triples.

543 TRIPLES      21 PREDICATES      106 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ncomms10013 schema:about N0ceaf743b84d4d7eba9074a57ea35a2d
2 N1ff2c6a7186e4c8082a1de39311892ef
3 N2ad18033453c4b43b45286bb5000423a
4 N38e5e5f1609145138251de0c622f3b56
5 N421ce727b5a84ebbb5d23c400b782ec9
6 N6fa32f173ef54ac58d53c479d9be8652
7 N79235f76ce8d4cd6b5f91124af341d20
8 N7d26c62aaf53469c874628e182b910b7
9 Na1a72101a54046f5ac54ba6d09afe0f0
10 Nb4991a557432475aa99dde3cb4276e69
11 Nb9000ae23d1044cfb173df79afdcaa10
12 Nd3010a7b2813481c8d85d0b183821f5e
13 Nde06e6dbf102469fb81e8fc2e8304079
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author Na0748af45af445e8acf06bcad4914487
17 schema:citation sg:pub.10.1007/s12032-013-0564-1
18 sg:pub.10.1038/nature09819
19 sg:pub.10.1038/nature10398
20 sg:pub.10.1038/nature11632
21 sg:pub.10.1038/ncomms5398
22 sg:pub.10.1038/ng0594-91
23 sg:pub.10.1038/ng1048
24 sg:pub.10.1038/nmeth0410-248
25 sg:pub.10.1038/nrc1696
26 sg:pub.10.1038/nrc2253
27 sg:pub.10.1038/nrm3417
28 sg:pub.10.1038/sj.onc.1208699
29 sg:pub.10.1038/sj.onc.1210582
30 sg:pub.10.1186/1472-6807-9-35
31 sg:pub.10.1186/gm415
32 sg:pub.10.1186/gm461
33 https://app.dimensions.ai/details/publication/pub.1074735182
34 https://doi.org/10.1002/1097-0142(197805)41:5<1937::aid-cncr2820410538>3.0.co;2-u
35 https://doi.org/10.1002/cncr.28239
36 https://doi.org/10.1002/pbc.24604
37 https://doi.org/10.1002/pros.10185
38 https://doi.org/10.1006/bcmd.2002.0525
39 https://doi.org/10.1016/j.ccell.2015.01.003
40 https://doi.org/10.1016/j.ccr.2009.12.040
41 https://doi.org/10.1016/j.cell.2007.05.022
42 https://doi.org/10.1016/j.cell.2014.09.049
43 https://doi.org/10.1016/j.cub.2009.02.055
44 https://doi.org/10.1016/j.molcel.2006.06.014
45 https://doi.org/10.1016/j.molcel.2010.01.026
46 https://doi.org/10.1016/j.ydbio.2012.05.030
47 https://doi.org/10.1016/s0022-5347(17)38582-8
48 https://doi.org/10.1016/s0092-8674(02)01084-x
49 https://doi.org/10.1073/pnas.0308531101
50 https://doi.org/10.1073/pnas.091062498
51 https://doi.org/10.1073/pnas.1107107108
52 https://doi.org/10.1074/jbc.m109.017442
53 https://doi.org/10.1074/jbc.m112.409102
54 https://doi.org/10.1074/jbc.m601903200
55 https://doi.org/10.1093/bioinformatics/bti770
56 https://doi.org/10.1093/bioinformatics/btn624
57 https://doi.org/10.1093/bioinformatics/btq330
58 https://doi.org/10.1093/bioinformatics/btr032
59 https://doi.org/10.1093/biomet/73.1.1
60 https://doi.org/10.1093/hmg/ddl444
61 https://doi.org/10.1093/nar/29.1.308
62 https://doi.org/10.1093/nar/gkq929
63 https://doi.org/10.1101/gad.2059211
64 https://doi.org/10.1126/science.1181498
65 https://doi.org/10.1128/mcb.00182-12
66 https://doi.org/10.1128/mcb.02076-07
67 https://doi.org/10.1136/jmg.2006.041723
68 https://doi.org/10.1139/o08-111
69 https://doi.org/10.1182/blood-2007-05-090514
70 https://doi.org/10.1200/jco.2005.01.2799
71 https://doi.org/10.1200/jco.2010.31.5192
72 https://doi.org/10.1371/journal.pbio.1000249
73 https://doi.org/10.1371/journal.pgen.1000190
74 https://doi.org/10.1371/journal.pone.0046688
75 https://doi.org/10.1371/journal.pone.0061055
76 https://doi.org/10.1593/neo.12714
77 https://doi.org/10.3109/15513819009067094
78 https://doi.org/10.3324/haematol.2008.002436
79 https://doi.org/10.3389/fgene.2012.00270
80 https://doi.org/10.4161/epi.5.7.12856
81 schema:datePublished 2015-12
82 schema:datePublishedReg 2015-12-01
83 schema:description Wilms tumour is an embryonal tumour of childhood that closely resembles the developing kidney. Genomic changes responsible for the development of the majority of Wilms tumours remain largely unknown. Here we identify recurrent mutations within Wilms tumours that involve the highly conserved YEATS domain of MLLT1 (ENL), a gene known to be involved in transcriptional elongation during early development. The mutant MLLT1 protein shows altered binding to acetylated histone tails. Moreover, MLLT1-mutant tumours show an increase in MYC gene expression and HOX dysregulation. Patients with MLLT1-mutant tumours present at a younger age and have a high prevalence of precursor intralobar nephrogenic rests. These data support a model whereby activating MLLT1 mutations early in renal development result in the development of Wilms tumour.
84 schema:genre research_article
85 schema:inLanguage en
86 schema:isAccessibleForFree true
87 schema:isPartOf N6a462d6d5c3b4f71a4b8165213162f4a
88 N948f74d8de454be1bd2cc58c271cf4ea
89 sg:journal.1043282
90 schema:name MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours
91 schema:pagination 10013
92 schema:productId N149e6ba4527a47d5ba0f85a825272206
93 N789c52d6c35b4562b1cb8e4293854512
94 Nb21f27c890c04010a65baef305cb5631
95 Nb2ee97cd0ee04de2aea2b25d2e8c32f2
96 Ne39259498c904e3cb8e80f0489213796
97 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036403844
98 https://doi.org/10.1038/ncomms10013
99 schema:sdDatePublished 2019-04-11T00:23
100 schema:sdLicense https://scigraph.springernature.com/explorer/license/
101 schema:sdPublisher N2be6fb1c26364d41b28500ceeae999e9
102 schema:url https://www.nature.com/articles/ncomms10013
103 sgo:license sg:explorer/license/
104 sgo:sdDataset articles
105 rdf:type schema:ScholarlyArticle
106 N015546d8a9c747f39e0d8c8ed7b8786b rdf:first sg:person.013732223267.18
107 rdf:rest N5c18e25801014e489aa9ab23a77b1f5e
108 N0ceaf743b84d4d7eba9074a57ea35a2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Cohort Studies
110 rdf:type schema:DefinedTerm
111 N0dcf7badb55a46dd9acc110f97887b5f rdf:first sg:person.07540064457.10
112 rdf:rest Ne51dfdb5decd489b855baaffbc22ba3c
113 N149e6ba4527a47d5ba0f85a825272206 schema:name dimensions_id
114 schema:value pub.1036403844
115 rdf:type schema:PropertyValue
116 N1921d6deb1114770aef69471adad7a27 rdf:first sg:person.0716572051.58
117 rdf:rest N99e3e1df70f240928583a97edb6b0e7b
118 N1e41a49283534e91b9e00776801d0f2b rdf:first sg:person.0673716355.40
119 rdf:rest N68be7386b21a453b93b996b748109ace
120 N1e5624ed8ca2464e819a5aad501db0a0 rdf:first sg:person.01010144755.82
121 rdf:rest Nccaa662cd11f4913997df59793697fa7
122 N1ff2c6a7186e4c8082a1de39311892ef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Protein Structure, Tertiary
124 rdf:type schema:DefinedTerm
125 N241b0d4ead27473a94ced25d7ce00ab9 rdf:first sg:person.01117110520.42
126 rdf:rest N895389a6702f46afba873ff7f0d3ff5f
127 N2ad18033453c4b43b45286bb5000423a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Humans
129 rdf:type schema:DefinedTerm
130 N2be6fb1c26364d41b28500ceeae999e9 schema:name Springer Nature - SN SciGraph project
131 rdf:type schema:Organization
132 N2fbe4ff1bd6546619d816f6a3d730c4b rdf:first sg:person.0671073025.86
133 rdf:rest N5636b0af09184ac7a8674a215ddc887d
134 N35b64cd5acf14a199be59b717a8b6415 rdf:first sg:person.0732441037.42
135 rdf:rest Nc9593955e0d64c10b8351cae6a8ad2bf
136 N38e5e5f1609145138251de0c622f3b56 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Protein Binding
138 rdf:type schema:DefinedTerm
139 N421ce727b5a84ebbb5d23c400b782ec9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Wilms Tumor
141 rdf:type schema:DefinedTerm
142 N5636b0af09184ac7a8674a215ddc887d rdf:first sg:person.0640762041.00
143 rdf:rest N7ca9355e4d4e47e3bb8b1521a91685e8
144 N5c18e25801014e489aa9ab23a77b1f5e rdf:first sg:person.01036437235.58
145 rdf:rest N6a3a15fe95b448819c3d31bf50c34d2e
146 N68be7386b21a453b93b996b748109ace rdf:first sg:person.0706310437.21
147 rdf:rest N9e65f566e115417eb749b4f89c437d39
148 N6a3a15fe95b448819c3d31bf50c34d2e rdf:first sg:person.01361404112.36
149 rdf:rest N0dcf7badb55a46dd9acc110f97887b5f
150 N6a462d6d5c3b4f71a4b8165213162f4a schema:issueNumber 1
151 rdf:type schema:PublicationIssue
152 N6fa32f173ef54ac58d53c479d9be8652 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Transcription Factors
154 rdf:type schema:DefinedTerm
155 N789c52d6c35b4562b1cb8e4293854512 schema:name nlm_unique_id
156 schema:value 101528555
157 rdf:type schema:PropertyValue
158 N79235f76ce8d4cd6b5f91124af341d20 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Kidney
160 rdf:type schema:DefinedTerm
161 N7ca9355e4d4e47e3bb8b1521a91685e8 rdf:first sg:person.0764131534.48
162 rdf:rest N241b0d4ead27473a94ced25d7ce00ab9
163 N7d26c62aaf53469c874628e182b910b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Kidney Neoplasms
165 rdf:type schema:DefinedTerm
166 N895389a6702f46afba873ff7f0d3ff5f rdf:first sg:person.01146630513.79
167 rdf:rest Nf938805c07fd43f2a336df64de6879c6
168 N948f74d8de454be1bd2cc58c271cf4ea schema:volumeNumber 6
169 rdf:type schema:PublicationVolume
170 N99e3e1df70f240928583a97edb6b0e7b rdf:first sg:person.0632564577.34
171 rdf:rest N015546d8a9c747f39e0d8c8ed7b8786b
172 N9e65f566e115417eb749b4f89c437d39 rdf:first sg:person.01047057656.72
173 rdf:rest Nbf04cbfdaccc4a65bb9374ac4bd69acf
174 Na0748af45af445e8acf06bcad4914487 rdf:first sg:person.01361007034.71
175 rdf:rest N1e41a49283534e91b9e00776801d0f2b
176 Na1a72101a54046f5ac54ba6d09afe0f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Mutation
178 rdf:type schema:DefinedTerm
179 Nb0d6aad25d8a45e0a1785e5609fa9ab6 rdf:first sg:person.01030532166.57
180 rdf:rest N1921d6deb1114770aef69471adad7a27
181 Nb21f27c890c04010a65baef305cb5631 schema:name readcube_id
182 schema:value ad6a39606c4992d1443639df21b0e219a492a111e3e2c12b4dde7f5e6cca06e2
183 rdf:type schema:PropertyValue
184 Nb2ee97cd0ee04de2aea2b25d2e8c32f2 schema:name pubmed_id
185 schema:value 26635203
186 rdf:type schema:PropertyValue
187 Nb4991a557432475aa99dde3cb4276e69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Nuclear Proteins
189 rdf:type schema:DefinedTerm
190 Nb9000ae23d1044cfb173df79afdcaa10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name Neoplasm Proteins
192 rdf:type schema:DefinedTerm
193 Nb9164c0b5aba476d8adad63b8e35ba71 rdf:first sg:person.01220513165.63
194 rdf:rest rdf:nil
195 Nbf04cbfdaccc4a65bb9374ac4bd69acf rdf:first sg:person.014015600757.41
196 rdf:rest N1e5624ed8ca2464e819a5aad501db0a0
197 Nc9593955e0d64c10b8351cae6a8ad2bf rdf:first sg:person.01150455763.02
198 rdf:rest N2fbe4ff1bd6546619d816f6a3d730c4b
199 Nccaa662cd11f4913997df59793697fa7 rdf:first sg:person.0753532033.74
200 rdf:rest Nb0d6aad25d8a45e0a1785e5609fa9ab6
201 Nd3010a7b2813481c8d85d0b183821f5e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
202 schema:name Proto-Oncogene Proteins c-myc
203 rdf:type schema:DefinedTerm
204 Nde06e6dbf102469fb81e8fc2e8304079 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
205 schema:name Histones
206 rdf:type schema:DefinedTerm
207 Nde3408c5591443f7938af30a4898dfd6 rdf:first sg:person.0627357425.48
208 rdf:rest N35b64cd5acf14a199be59b717a8b6415
209 Ne39259498c904e3cb8e80f0489213796 schema:name doi
210 schema:value 10.1038/ncomms10013
211 rdf:type schema:PropertyValue
212 Ne51dfdb5decd489b855baaffbc22ba3c rdf:first sg:person.01276051237.43
213 rdf:rest Nde3408c5591443f7938af30a4898dfd6
214 Ne5370d8bdb3f4b0a82581b48938e7ca3 schema:name Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, Ohio 43205, USA
215 rdf:type schema:Organization
216 Neb49aa8cd91a4ae7854f35176f851569 schema:name Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, Ohio 43205, USA
217 rdf:type schema:Organization
218 Nf938805c07fd43f2a336df64de6879c6 rdf:first sg:person.0621523641.36
219 rdf:rest Nb9164c0b5aba476d8adad63b8e35ba71
220 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
221 schema:name Medical and Health Sciences
222 rdf:type schema:DefinedTerm
223 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
224 schema:name Clinical Sciences
225 rdf:type schema:DefinedTerm
226 sg:grant.2343593 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms10013
227 rdf:type schema:MonetaryGrant
228 sg:grant.2438833 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms10013
229 rdf:type schema:MonetaryGrant
230 sg:grant.2688942 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms10013
231 rdf:type schema:MonetaryGrant
232 sg:grant.2693529 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms10013
233 rdf:type schema:MonetaryGrant
234 sg:grant.2693700 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms10013
235 rdf:type schema:MonetaryGrant
236 sg:grant.2696311 http://pending.schema.org/fundedItem sg:pub.10.1038/ncomms10013
237 rdf:type schema:MonetaryGrant
238 sg:journal.1043282 schema:issn 2041-1723
239 schema:name Nature Communications
240 rdf:type schema:Periodical
241 sg:person.01010144755.82 schema:affiliation https://www.grid.ac/institutes/grid.413808.6
242 schema:familyName Jennings
243 schema:givenName Lawrence
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010144755.82
245 rdf:type schema:Person
246 sg:person.01030532166.57 schema:affiliation https://www.grid.ac/institutes/grid.48336.3a
247 schema:familyName Auvil
248 schema:givenName Jaime M. Guidry
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030532166.57
250 rdf:type schema:Person
251 sg:person.01036437235.58 schema:affiliation https://www.grid.ac/institutes/grid.94365.3d
252 schema:familyName Hsu
253 schema:givenName Chih Hao
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036437235.58
255 rdf:type schema:Person
256 sg:person.01047057656.72 schema:affiliation https://www.grid.ac/institutes/grid.45672.32
257 schema:familyName Radhakrishnan
258 schema:givenName Anand
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047057656.72
260 rdf:type schema:Person
261 sg:person.01117110520.42 schema:affiliation Ne5370d8bdb3f4b0a82581b48938e7ca3
262 schema:familyName Hampton
263 schema:givenName Oliver A.
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117110520.42
265 rdf:type schema:Person
266 sg:person.01146630513.79 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
267 schema:familyName Gastier-Foster
268 schema:givenName Julie M.
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146630513.79
270 rdf:type schema:Person
271 sg:person.01150455763.02 schema:affiliation https://www.grid.ac/institutes/grid.248762.d
272 schema:familyName Marra
273 schema:givenName Marco A.
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150455763.02
275 rdf:type schema:Person
276 sg:person.01220513165.63 schema:affiliation https://www.grid.ac/institutes/grid.48336.3a
277 schema:familyName Smith
278 schema:givenName Malcolm A.
279 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220513165.63
280 rdf:type schema:Person
281 sg:person.01276051237.43 schema:affiliation https://www.grid.ac/institutes/grid.248762.d
282 schema:familyName Ma
283 schema:givenName Yussanne
284 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276051237.43
285 rdf:type schema:Person
286 sg:person.01361007034.71 schema:affiliation https://www.grid.ac/institutes/grid.413808.6
287 schema:familyName Perlman
288 schema:givenName Elizabeth J.
289 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361007034.71
290 rdf:type schema:Person
291 sg:person.01361404112.36 schema:affiliation https://www.grid.ac/institutes/grid.94365.3d
292 schema:familyName Nguyen
293 schema:givenName Cu
294 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361404112.36
295 rdf:type schema:Person
296 sg:person.013732223267.18 schema:affiliation https://www.grid.ac/institutes/grid.94365.3d
297 schema:familyName Meerzaman
298 schema:givenName Daoud
299 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013732223267.18
300 rdf:type schema:Person
301 sg:person.014015600757.41 schema:affiliation https://www.grid.ac/institutes/grid.48336.3a
302 schema:familyName Gerhard
303 schema:givenName Daniela S.
304 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014015600757.41
305 rdf:type schema:Person
306 sg:person.0621523641.36 schema:affiliation https://www.grid.ac/institutes/grid.39382.33
307 schema:familyName Ross
308 schema:givenName Nicole
309 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621523641.36
310 rdf:type schema:Person
311 sg:person.0627357425.48 schema:affiliation https://www.grid.ac/institutes/grid.248762.d
312 schema:familyName Mungall
313 schema:givenName Andrew J.
314 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627357425.48
315 rdf:type schema:Person
316 sg:person.0632564577.34 schema:affiliation https://www.grid.ac/institutes/grid.239560.b
317 schema:familyName Dome
318 schema:givenName Jeffrey S.
319 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632564577.34
320 rdf:type schema:Person
321 sg:person.0640762041.00 schema:affiliation https://www.grid.ac/institutes/grid.240871.8
322 schema:familyName Ma
323 schema:givenName Jing
324 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640762041.00
325 rdf:type schema:Person
326 sg:person.0671073025.86 schema:affiliation https://www.grid.ac/institutes/grid.240871.8
327 schema:familyName Mullighan
328 schema:givenName Charles G.
329 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671073025.86
330 rdf:type schema:Person
331 sg:person.0673716355.40 schema:affiliation https://www.grid.ac/institutes/grid.413808.6
332 schema:familyName Gadd
333 schema:givenName Samantha
334 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673716355.40
335 rdf:type schema:Person
336 sg:person.0706310437.21 schema:affiliation https://www.grid.ac/institutes/grid.45672.32
337 schema:familyName Arold
338 schema:givenName Stefan T.
339 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706310437.21
340 rdf:type schema:Person
341 sg:person.0716572051.58 schema:affiliation https://www.grid.ac/institutes/grid.48336.3a
342 schema:familyName Davidsen
343 schema:givenName Tanja M.
344 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716572051.58
345 rdf:type schema:Person
346 sg:person.0732441037.42 schema:affiliation https://www.grid.ac/institutes/grid.248762.d
347 schema:familyName Moore
348 schema:givenName Richard A.
349 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732441037.42
350 rdf:type schema:Person
351 sg:person.0753532033.74 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
352 schema:familyName Huff
353 schema:givenName Vicki
354 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753532033.74
355 rdf:type schema:Person
356 sg:person.07540064457.10 schema:affiliation https://www.grid.ac/institutes/grid.421586.c
357 schema:familyName Anderson
358 schema:givenName James
359 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07540064457.10
360 rdf:type schema:Person
361 sg:person.0764131534.48 schema:affiliation Neb49aa8cd91a4ae7854f35176f851569
362 schema:familyName Wheeler
363 schema:givenName David A.
364 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764131534.48
365 rdf:type schema:Person
366 sg:pub.10.1007/s12032-013-0564-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040622823
367 https://doi.org/10.1007/s12032-013-0564-1
368 rdf:type schema:CreativeWork
369 sg:pub.10.1038/nature09819 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029739875
370 https://doi.org/10.1038/nature09819
371 rdf:type schema:CreativeWork
372 sg:pub.10.1038/nature10398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018204822
373 https://doi.org/10.1038/nature10398
374 rdf:type schema:CreativeWork
375 sg:pub.10.1038/nature11632 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000661742
376 https://doi.org/10.1038/nature11632
377 rdf:type schema:CreativeWork
378 sg:pub.10.1038/ncomms5398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000289049
379 https://doi.org/10.1038/ncomms5398
380 rdf:type schema:CreativeWork
381 sg:pub.10.1038/ng0594-91 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001746104
382 https://doi.org/10.1038/ng0594-91
383 rdf:type schema:CreativeWork
384 sg:pub.10.1038/ng1048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019623099
385 https://doi.org/10.1038/ng1048
386 rdf:type schema:CreativeWork
387 sg:pub.10.1038/nmeth0410-248 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007489634
388 https://doi.org/10.1038/nmeth0410-248
389 rdf:type schema:CreativeWork
390 sg:pub.10.1038/nrc1696 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034028024
391 https://doi.org/10.1038/nrc1696
392 rdf:type schema:CreativeWork
393 sg:pub.10.1038/nrc2253 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035045408
394 https://doi.org/10.1038/nrc2253
395 rdf:type schema:CreativeWork
396 sg:pub.10.1038/nrm3417 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037885873
397 https://doi.org/10.1038/nrm3417
398 rdf:type schema:CreativeWork
399 sg:pub.10.1038/sj.onc.1208699 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019968921
400 https://doi.org/10.1038/sj.onc.1208699
401 rdf:type schema:CreativeWork
402 sg:pub.10.1038/sj.onc.1210582 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013831372
403 https://doi.org/10.1038/sj.onc.1210582
404 rdf:type schema:CreativeWork
405 sg:pub.10.1186/1472-6807-9-35 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003576798
406 https://doi.org/10.1186/1472-6807-9-35
407 rdf:type schema:CreativeWork
408 sg:pub.10.1186/gm415 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011030823
409 https://doi.org/10.1186/gm415
410 rdf:type schema:CreativeWork
411 sg:pub.10.1186/gm461 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015036269
412 https://doi.org/10.1186/gm461
413 rdf:type schema:CreativeWork
414 https://app.dimensions.ai/details/publication/pub.1074735182 schema:CreativeWork
415 https://doi.org/10.1002/1097-0142(197805)41:5<1937::aid-cncr2820410538>3.0.co;2-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1014465903
416 rdf:type schema:CreativeWork
417 https://doi.org/10.1002/cncr.28239 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014261208
418 rdf:type schema:CreativeWork
419 https://doi.org/10.1002/pbc.24604 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037998819
420 rdf:type schema:CreativeWork
421 https://doi.org/10.1002/pros.10185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045017388
422 rdf:type schema:CreativeWork
423 https://doi.org/10.1006/bcmd.2002.0525 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038939572
424 rdf:type schema:CreativeWork
425 https://doi.org/10.1016/j.ccell.2015.01.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026617605
426 rdf:type schema:CreativeWork
427 https://doi.org/10.1016/j.ccr.2009.12.040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005535275
428 rdf:type schema:CreativeWork
429 https://doi.org/10.1016/j.cell.2007.05.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051644950
430 rdf:type schema:CreativeWork
431 https://doi.org/10.1016/j.cell.2014.09.049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031055580
432 rdf:type schema:CreativeWork
433 https://doi.org/10.1016/j.cub.2009.02.055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044969059
434 rdf:type schema:CreativeWork
435 https://doi.org/10.1016/j.molcel.2006.06.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005228370
436 rdf:type schema:CreativeWork
437 https://doi.org/10.1016/j.molcel.2010.01.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000655450
438 rdf:type schema:CreativeWork
439 https://doi.org/10.1016/j.ydbio.2012.05.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044574523
440 rdf:type schema:CreativeWork
441 https://doi.org/10.1016/s0022-5347(17)38582-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077655553
442 rdf:type schema:CreativeWork
443 https://doi.org/10.1016/s0092-8674(02)01084-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005479566
444 rdf:type schema:CreativeWork
445 https://doi.org/10.1073/pnas.0308531101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001366510
446 rdf:type schema:CreativeWork
447 https://doi.org/10.1073/pnas.091062498 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001631710
448 rdf:type schema:CreativeWork
449 https://doi.org/10.1073/pnas.1107107108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005396588
450 rdf:type schema:CreativeWork
451 https://doi.org/10.1074/jbc.m109.017442 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032954243
452 rdf:type schema:CreativeWork
453 https://doi.org/10.1074/jbc.m112.409102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048562624
454 rdf:type schema:CreativeWork
455 https://doi.org/10.1074/jbc.m601903200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009441389
456 rdf:type schema:CreativeWork
457 https://doi.org/10.1093/bioinformatics/bti770 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031081661
458 rdf:type schema:CreativeWork
459 https://doi.org/10.1093/bioinformatics/btn624 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037879241
460 rdf:type schema:CreativeWork
461 https://doi.org/10.1093/bioinformatics/btq330 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047117020
462 rdf:type schema:CreativeWork
463 https://doi.org/10.1093/bioinformatics/btr032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017115352
464 rdf:type schema:CreativeWork
465 https://doi.org/10.1093/biomet/73.1.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059419563
466 rdf:type schema:CreativeWork
467 https://doi.org/10.1093/hmg/ddl444 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003197230
468 rdf:type schema:CreativeWork
469 https://doi.org/10.1093/nar/29.1.308 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005817660
470 rdf:type schema:CreativeWork
471 https://doi.org/10.1093/nar/gkq929 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005486377
472 rdf:type schema:CreativeWork
473 https://doi.org/10.1101/gad.2059211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002057650
474 rdf:type schema:CreativeWork
475 https://doi.org/10.1126/science.1181498 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014947319
476 rdf:type schema:CreativeWork
477 https://doi.org/10.1128/mcb.00182-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045722449
478 rdf:type schema:CreativeWork
479 https://doi.org/10.1128/mcb.02076-07 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028755884
480 rdf:type schema:CreativeWork
481 https://doi.org/10.1136/jmg.2006.041723 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020542404
482 rdf:type schema:CreativeWork
483 https://doi.org/10.1139/o08-111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052666969
484 rdf:type schema:CreativeWork
485 https://doi.org/10.1182/blood-2007-05-090514 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027305941
486 rdf:type schema:CreativeWork
487 https://doi.org/10.1200/jco.2005.01.2799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017832430
488 rdf:type schema:CreativeWork
489 https://doi.org/10.1200/jco.2010.31.5192 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018710861
490 rdf:type schema:CreativeWork
491 https://doi.org/10.1371/journal.pbio.1000249 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028688446
492 rdf:type schema:CreativeWork
493 https://doi.org/10.1371/journal.pgen.1000190 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014802806
494 rdf:type schema:CreativeWork
495 https://doi.org/10.1371/journal.pone.0046688 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043907803
496 rdf:type schema:CreativeWork
497 https://doi.org/10.1371/journal.pone.0061055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020348126
498 rdf:type schema:CreativeWork
499 https://doi.org/10.1593/neo.12714 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008209714
500 rdf:type schema:CreativeWork
501 https://doi.org/10.3109/15513819009067094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014227988
502 rdf:type schema:CreativeWork
503 https://doi.org/10.3324/haematol.2008.002436 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025448661
504 rdf:type schema:CreativeWork
505 https://doi.org/10.3389/fgene.2012.00270 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012225562
506 rdf:type schema:CreativeWork
507 https://doi.org/10.4161/epi.5.7.12856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072303045
508 rdf:type schema:CreativeWork
509 https://www.grid.ac/institutes/grid.239560.b schema:alternateName Children’s National Health System
510 schema:name Department of Pediatrics, Division of Pediatric Hematology/Oncology, Children’s National Medical Center, 111 Michigan Avenue, NW, Washington DC 20010, USA
511 rdf:type schema:Organization
512 https://www.grid.ac/institutes/grid.240145.6 schema:alternateName The University of Texas MD Anderson Cancer Center
513 schema:name Department of Genetics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas 77030, USA
514 rdf:type schema:Organization
515 https://www.grid.ac/institutes/grid.240871.8 schema:alternateName St. Jude Children's Research Hospital
516 schema:name Department of Pathology, St Jude Children’s Research Hospital, 262 Danny Thomas Place, Mail Stop 342, Memphis, Tennessee 38105, USA
517 rdf:type schema:Organization
518 https://www.grid.ac/institutes/grid.248762.d schema:alternateName BC Cancer Agency
519 schema:name Canada’s Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada V5Z 4S6
520 rdf:type schema:Organization
521 https://www.grid.ac/institutes/grid.261331.4 schema:alternateName The Ohio State University
522 schema:name Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
523 Departments of Pathology and Pediatrics, Ohio State University College of Medicine, 700 Children's Drive, Columbus, Ohio 43205, USA
524 rdf:type schema:Organization
525 https://www.grid.ac/institutes/grid.39382.33 schema:alternateName Baylor College of Medicine
526 schema:name Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
527 rdf:type schema:Organization
528 https://www.grid.ac/institutes/grid.413808.6 schema:alternateName Lurie Children's Hospital
529 schema:name Department of Pathology, Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University’s Feinberg School of Medicine, 225 E. Chicago Ave, Chicago, Illinosis 60611, USA
530 rdf:type schema:Organization
531 https://www.grid.ac/institutes/grid.421586.c schema:alternateName Frontier Science & Technology Research Foundation
532 schema:name Frontier Science and Technology Research Foundation, 505 S. Rosa Rd #100, Madison, Wisconsin 53719, USA
533 rdf:type schema:Organization
534 https://www.grid.ac/institutes/grid.45672.32 schema:alternateName King Abdullah University of Science and Technology
535 schema:name King Abdullah University of Science and Technology, Department of Biochemistry and Molecular Biology, Division of Biological and Environmental Sciences and Engineering, Computational Bioscience Research Center, Thuwal 23955, Saudi Arabia
536 rdf:type schema:Organization
537 https://www.grid.ac/institutes/grid.48336.3a schema:alternateName National Cancer Institute
538 schema:name Cancer Therapy Evaluation Program, National Cancer Institute, 9609 Medical Center Drive, RM 5-W414, MSC 9737, Bethesda, Maryland 20892, USA
539 Office of Cancer Genomics, National Cancer Institute, 31 Center Drive, Bethesda, Maryland 20892, USA
540 rdf:type schema:Organization
541 https://www.grid.ac/institutes/grid.94365.3d schema:alternateName National Institutes of Health
542 schema:name Center for Biomedical Informatics and Information Technology, National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Bethesda, Maryland 20892, USA
543 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...