Mechanistic insights into a Ca2+-dependent family of α-mannosidases in a human gut symbiont View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-12-27

AUTHORS

Yanping Zhu, Michael D L Suits, Andrew J Thompson, Sambhaji Chavan, Zoran Dinev, Claire Dumon, Nicola Smith, Kelley W Moremen, Yong Xiang, Aloysius Siriwardena, Spencer J Williams, Harry J Gilbert, Gideon J Davies

ABSTRACT

Gut bacteria utilize dietary and host oligosaccharides for nutrients. Structural and biochemical evidence now demonstrates a conserved catalytic mechanism but diverse substrate preferences for a family of glycoside hydrolases, explaining how they break down complex glycans.

PAGES

125-132

Journal

TITLE

Nature Chemical Biology

ISSUE

2

VOLUME

6

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nchembio.278

DOI

http://dx.doi.org/10.1038/nchembio.278

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011257060

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20081828


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