Mapping the functional yeast ABC transporter interactome View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-09

AUTHORS

Jamie Snider, Asad Hanif, Mid Eum Lee, Ke Jin, Analyn R Yu, Chris Graham, Matthew Chuk, Dunja Damjanovic, Marta Wierzbicka, Priscilla Tang, Dina Balderes, Victoria Wong, Matthew Jessulat, Katelyn D Darowski, Bryan-Joseph San Luis, Igor Shevelev, Stephen L Sturley, Charles Boone, Jack F Greenblatt, Zhaolei Zhang, Christian M Paumi, Mohan Babu, Hay-Oak Park, Susan Michaelis, Igor Stagljar

ABSTRACT

ATP-binding cassette (ABC) transporters are a ubiquitous class of integral membrane proteins of immense clinical interest because of their strong association with human disease and pharmacology. To improve our understanding of these proteins, we used membrane yeast two-hybrid technology to map the protein interactome of all of the nonmitochondrial ABC transporters in the model organism Saccharomyces cerevisiae and combined this data with previously reported yeast ABC transporter interactions in the BioGRID database to generate a comprehensive, integrated 'interactome'. We show that ABC transporters physically associate with proteins involved in an unexpectedly diverse range of functions. We specifically examine the importance of the physical interactions of ABC transporters in both the regulation of one another and in the modulation of proteins involved in zinc homeostasis. The interaction network presented here will be a powerful resource for increasing our fundamental understanding of the cellular role and regulation of ABC transporters. More... »

PAGES

565-572

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nchembio.1293

DOI

http://dx.doi.org/10.1038/nchembio.1293

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012238186

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23831759


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "ATP-Binding Cassette Transporters", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Binding", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Interaction Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomyces cerevisiae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Two-Hybrid System Techniques", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Snider", 
        "givenName": "Jamie", 
        "id": "sg:person.0761173360.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761173360.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hanif", 
        "givenName": "Asad", 
        "id": "sg:person.01037275306.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01037275306.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "Molecular Cellular Developmental Biology Program, The Ohio State University, Columbus, Ohio, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Mid Eum", 
        "id": "sg:person.0762055672.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762055672.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.", 
            "Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jin", 
        "givenName": "Ke", 
        "id": "sg:person.0734673546.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734673546.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yu", 
        "givenName": "Analyn R", 
        "id": "sg:person.01076304272.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076304272.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Regina", 
          "id": "https://www.grid.ac/institutes/grid.57926.3f", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Graham", 
        "givenName": "Chris", 
        "id": "sg:person.01156503215.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156503215.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chuk", 
        "givenName": "Matthew", 
        "id": "sg:person.0713060160.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713060160.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Damjanovic", 
        "givenName": "Dunja", 
        "id": "sg:person.01260646072.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260646072.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wierzbicka", 
        "givenName": "Marta", 
        "id": "sg:person.01326761272.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326761272.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tang", 
        "givenName": "Priscilla", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Columbia University Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.239585.0", 
          "name": [
            "Department of Pediatrics, Columbia University Medical Center, New York, New York, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Balderes", 
        "givenName": "Dina", 
        "id": "sg:person.01126012112.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126012112.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wong", 
        "givenName": "Victoria", 
        "id": "sg:person.0717603572.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717603572.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Regina", 
          "id": "https://www.grid.ac/institutes/grid.57926.3f", 
          "name": [
            "Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jessulat", 
        "givenName": "Matthew", 
        "id": "sg:person.0656250576.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656250576.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Darowski", 
        "givenName": "Katelyn D", 
        "id": "sg:person.01034032172.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034032172.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.", 
            "Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "San Luis", 
        "givenName": "Bryan-Joseph", 
        "id": "sg:person.01163167641.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163167641.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shevelev", 
        "givenName": "Igor", 
        "id": "sg:person.01133113243.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133113243.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Columbia University Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.239585.0", 
          "name": [
            "Department of Pediatrics, Columbia University Medical Center, New York, New York, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sturley", 
        "givenName": "Stephen L", 
        "id": "sg:person.0575365050.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575365050.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.", 
            "Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boone", 
        "givenName": "Charles", 
        "id": "sg:person.07755274557.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07755274557.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.", 
            "Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Greenblatt", 
        "givenName": "Jack F", 
        "id": "sg:person.01132056571.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132056571.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.", 
            "Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Zhaolei", 
        "id": "sg:person.01341434131.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341434131.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Kentucky", 
          "id": "https://www.grid.ac/institutes/grid.266539.d", 
          "name": [
            "Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Paumi", 
        "givenName": "Christian M", 
        "id": "sg:person.0657733713.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657733713.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Regina", 
          "id": "https://www.grid.ac/institutes/grid.57926.3f", 
          "name": [
            "Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Babu", 
        "givenName": "Mohan", 
        "id": "sg:person.016361100057.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016361100057.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "Molecular Cellular Developmental Biology Program, The Ohio State University, Columbus, Ohio, USA.", 
            "Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Park", 
        "givenName": "Hay-Oak", 
        "id": "sg:person.01326676141.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326676141.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Michaelis", 
        "givenName": "Susan", 
        "id": "sg:person.01263513605.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263513605.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.", 
            "Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stagljar", 
        "givenName": "Igor", 
        "id": "sg:person.0757201257.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757201257.74"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/j.1600-0854.2004.00168.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000089643"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00709-011-0360-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001106424", 
          "https://doi.org/10.1007/s00709-011-0360-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tibs.2009.06.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002350616"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00018-003-3336-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003175515", 
          "https://doi.org/10.1007/s00018-003-3336-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.genom.6.080604.162122", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003790951"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00232-009-9173-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004219036", 
          "https://doi.org/10.1007/s00232-009-9173-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00232-009-9173-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004219036", 
          "https://doi.org/10.1007/s00232-009-9173-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00232-009-9173-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004219036", 
          "https://doi.org/10.1007/s00232-009-9173-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.95.9.5187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004450825"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m204707200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005404483"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.r900014200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005710627"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt0102-87", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007758048", 
          "https://doi.org/10.1038/nbt0102-87"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt0102-87", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007758048", 
          "https://doi.org/10.1038/nbt0102-87"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0959-440x(03)00037-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008105088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0959-440x(03)00037-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008105088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m407600200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010151152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m302760200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010968773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.107.165324", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011246958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.107.165324", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011246958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.1362105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012511978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/yea.320110704", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013534752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/yea.320110704", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013534752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molcel.2007.03.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013829101"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature00935", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015995329", 
          "https://doi.org/10.1038/nature00935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature00935", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015995329", 
          "https://doi.org/10.1038/nature00935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature02046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016490499", 
          "https://doi.org/10.1038/nature02046"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature02046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016490499", 
          "https://doi.org/10.1038/nature02046"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m205052200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019295918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1097-2765(02)00496-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021038327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1097-0061(199807)14:10<953::aid-yea293>3.0.co;2-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026465198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1097-0061(199807)14:10<953::aid-yea293>3.0.co;2-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026465198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.111.130724", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027937620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.111.130724", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027937620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-59745-540-4_11", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028556580", 
          "https://doi.org/10.1007/978-1-59745-540-4_11"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/yea.1504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029234017"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.93.6.2454", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029610922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20110876", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029615519"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20110876", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029615519"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2010.83", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030643472", 
          "https://doi.org/10.1038/nprot.2010.83"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2010.83", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030643472", 
          "https://doi.org/10.1038/nprot.2010.83"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkp931", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031228115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkp931", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031228115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1091/mbc.e02-08-0501", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031889966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1012866803188", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033933064", 
          "https://doi.org/10.1023/a:1012866803188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkr1029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037074957"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tplants.2008.02.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037891467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2164-11-177", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038532952", 
          "https://doi.org/10.1186/1471-2164-11-177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.93.21.11901", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039394498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/cmr.00051-08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041710938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mmbr.00020-09", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041712681"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkq1116", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042062806"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrd1984", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042314065", 
          "https://doi.org/10.1038/nrd1984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrd1984", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042314065", 
          "https://doi.org/10.1038/nrd1984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/75556", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044135237", 
          "https://doi.org/10.1038/75556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/75556", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044135237", 
          "https://doi.org/10.1038/75556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/bth123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044410072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/bth456", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046132302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkn665", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047944503"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m300568200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051294346"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/ec.2.3.588-598.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051708196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.1239303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052744398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.febslet.2008.02.045", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053349590"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.gr-1649r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060407558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074804462", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1994.tb06627.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082624347"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-09", 
    "datePublishedReg": "2013-09-01", 
    "description": "ATP-binding cassette (ABC) transporters are a ubiquitous class of integral membrane proteins of immense clinical interest because of their strong association with human disease and pharmacology. To improve our understanding of these proteins, we used membrane yeast two-hybrid technology to map the protein interactome of all of the nonmitochondrial ABC transporters in the model organism Saccharomyces cerevisiae and combined this data with previously reported yeast ABC transporter interactions in the BioGRID database to generate a comprehensive, integrated 'interactome'. We show that ABC transporters physically associate with proteins involved in an unexpectedly diverse range of functions. We specifically examine the importance of the physical interactions of ABC transporters in both the regulation of one another and in the modulation of proteins involved in zinc homeostasis. The interaction network presented here will be a powerful resource for increasing our fundamental understanding of the cellular role and regulation of ABC transporters. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nchembio.1293", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2514484", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2519020", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1327431", 
        "issn": [
          "1552-4450", 
          "1552-4469"
        ], 
        "name": "Nature Chemical Biology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "9", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "9"
      }
    ], 
    "name": "Mapping the functional yeast ABC transporter interactome", 
    "pagination": "565-572", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "3a4e6eee2d39c0bf11909ea6982103544f7f3b2988f9b32db56b55f4cfa1ad3b"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23831759"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101231976"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nchembio.1293"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1012238186"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nchembio.1293", 
      "https://app.dimensions.ai/details/publication/pub.1012238186"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T21:24", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8687_00000422.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/nchembio.1293"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nchembio.1293'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nchembio.1293'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nchembio.1293'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nchembio.1293'


 

This table displays all metadata directly associated to this object as RDF triples.

441 TRIPLES      21 PREDICATES      84 URIs      26 LITERALS      14 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nchembio.1293 schema:about N408b85d08b604d5dab27a3f112fcaa9d
2 N4e6f214a3f794b1991713c100665c750
3 N7acbd16a097c47a58b399745444936c8
4 Nc4f7551effb947cb84018b8372d793f3
5 Nd0533f94f915465fa1c4b3474ed3f6dd
6 anzsrc-for:06
7 anzsrc-for:0601
8 schema:author N35be54468eab4cf18903226db42cb0f7
9 schema:citation sg:pub.10.1007/978-1-59745-540-4_11
10 sg:pub.10.1007/s00018-003-3336-9
11 sg:pub.10.1007/s00232-009-9173-5
12 sg:pub.10.1007/s00709-011-0360-8
13 sg:pub.10.1023/a:1012866803188
14 sg:pub.10.1038/75556
15 sg:pub.10.1038/nature00935
16 sg:pub.10.1038/nature02046
17 sg:pub.10.1038/nbt0102-87
18 sg:pub.10.1038/nprot.2010.83
19 sg:pub.10.1038/nrd1984
20 sg:pub.10.1186/1471-2164-11-177
21 https://app.dimensions.ai/details/publication/pub.1074804462
22 https://doi.org/10.1002/(sici)1097-0061(199807)14:10<953::aid-yea293>3.0.co;2-u
23 https://doi.org/10.1002/j.1460-2075.1994.tb06627.x
24 https://doi.org/10.1002/yea.1504
25 https://doi.org/10.1002/yea.320110704
26 https://doi.org/10.1016/j.febslet.2008.02.045
27 https://doi.org/10.1016/j.molcel.2007.03.011
28 https://doi.org/10.1016/j.tibs.2009.06.004
29 https://doi.org/10.1016/j.tplants.2008.02.001
30 https://doi.org/10.1016/s0959-440x(03)00037-x
31 https://doi.org/10.1016/s1097-2765(02)00496-3
32 https://doi.org/10.1042/bj20110876
33 https://doi.org/10.1073/pnas.93.21.11901
34 https://doi.org/10.1073/pnas.93.6.2454
35 https://doi.org/10.1073/pnas.95.9.5187
36 https://doi.org/10.1074/jbc.m204707200
37 https://doi.org/10.1074/jbc.m205052200
38 https://doi.org/10.1074/jbc.m300568200
39 https://doi.org/10.1074/jbc.m302760200
40 https://doi.org/10.1074/jbc.m407600200
41 https://doi.org/10.1074/jbc.r900014200
42 https://doi.org/10.1091/mbc.e02-08-0501
43 https://doi.org/10.1093/bioinformatics/bth123
44 https://doi.org/10.1093/bioinformatics/bth456
45 https://doi.org/10.1093/nar/gkn665
46 https://doi.org/10.1093/nar/gkp931
47 https://doi.org/10.1093/nar/gkq1116
48 https://doi.org/10.1093/nar/gkr1029
49 https://doi.org/10.1101/gad.1362105
50 https://doi.org/10.1101/gr.1239303
51 https://doi.org/10.1101/gr.gr-1649r
52 https://doi.org/10.1111/j.1600-0854.2004.00168.x
53 https://doi.org/10.1128/cmr.00051-08
54 https://doi.org/10.1128/ec.2.3.588-598.2003
55 https://doi.org/10.1128/mmbr.00020-09
56 https://doi.org/10.1146/annurev.genom.6.080604.162122
57 https://doi.org/10.1161/circresaha.107.165324
58 https://doi.org/10.1534/genetics.111.130724
59 schema:datePublished 2013-09
60 schema:datePublishedReg 2013-09-01
61 schema:description ATP-binding cassette (ABC) transporters are a ubiquitous class of integral membrane proteins of immense clinical interest because of their strong association with human disease and pharmacology. To improve our understanding of these proteins, we used membrane yeast two-hybrid technology to map the protein interactome of all of the nonmitochondrial ABC transporters in the model organism Saccharomyces cerevisiae and combined this data with previously reported yeast ABC transporter interactions in the BioGRID database to generate a comprehensive, integrated 'interactome'. We show that ABC transporters physically associate with proteins involved in an unexpectedly diverse range of functions. We specifically examine the importance of the physical interactions of ABC transporters in both the regulation of one another and in the modulation of proteins involved in zinc homeostasis. The interaction network presented here will be a powerful resource for increasing our fundamental understanding of the cellular role and regulation of ABC transporters.
62 schema:genre research_article
63 schema:inLanguage en
64 schema:isAccessibleForFree true
65 schema:isPartOf Nbe412ea800184da69450067687425384
66 Nca0b3775a1f040b099885e0358303764
67 sg:journal.1327431
68 schema:name Mapping the functional yeast ABC transporter interactome
69 schema:pagination 565-572
70 schema:productId N561be497199a4488a4b50a410985fa36
71 N7a577571774e4b37983b74d61eb7f22b
72 Na19c574215e3465f8a669c39a0c04f36
73 Nc8f9292b2663409ea53deecd96b8069f
74 Nef26dc56885e4c9ea1cd19ccd1193dc0
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012238186
76 https://doi.org/10.1038/nchembio.1293
77 schema:sdDatePublished 2019-04-10T21:24
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher Nb5c62de349024395b0049ec9d71909bd
80 schema:url http://www.nature.com/articles/nchembio.1293
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N027fbc016aad4f81bc09ef9d5199716e rdf:first sg:person.0575365050.38
85 rdf:rest N543c9f7e625147c7a317fea8063225a8
86 N031ddd40b0944d02a6ffaadd86bd159b rdf:first sg:person.01132056571.21
87 rdf:rest Ne7e30ac3ebcb4e4a9f77d32145636f0c
88 N07557d48b0944cc7861c61e1aecd208d rdf:first sg:person.01076304272.13
89 rdf:rest N420679103af8478a90b4a996f68c68b7
90 N0768797a89d6449fba1f281ebb6a4d67 rdf:first sg:person.01133113243.47
91 rdf:rest N027fbc016aad4f81bc09ef9d5199716e
92 N087c33119c184df4b286e75d567a2a43 rdf:first sg:person.0762055672.24
93 rdf:rest N797ec86aec304642ae63cdda2fd225d1
94 N0b45ff4e124f4cf69a2f62e1db3b5635 rdf:first sg:person.01034032172.28
95 rdf:rest Na352b2314c2b424db501aefe667f791f
96 N1585c05209c345f89e373929eb88f7e9 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
97 schema:familyName Tang
98 schema:givenName Priscilla
99 rdf:type schema:Person
100 N27e0611457da4a09896a65e1f6b5cbb9 rdf:first sg:person.01263513605.20
101 rdf:rest N407140baf72749cd8f7b7d2c3604005a
102 N28c2cb34170c435c826f4b748a34a814 rdf:first sg:person.01126012112.31
103 rdf:rest Neb80fbcf06b547fbaabc3feaa9f02f63
104 N35be54468eab4cf18903226db42cb0f7 rdf:first sg:person.0761173360.61
105 rdf:rest N5658d29d302d41db98ff2d4cddbc64ed
106 N407140baf72749cd8f7b7d2c3604005a rdf:first sg:person.0757201257.74
107 rdf:rest rdf:nil
108 N408b85d08b604d5dab27a3f112fcaa9d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Saccharomyces cerevisiae
110 rdf:type schema:DefinedTerm
111 N420679103af8478a90b4a996f68c68b7 rdf:first sg:person.01156503215.89
112 rdf:rest Ncfcf4b48450b4b10ae4a055de6354e2c
113 N43ffa52301c64b67abc3e9e06c4de648 rdf:first sg:person.01260646072.07
114 rdf:rest N670a026951874a1fbc7a06d1cf387740
115 N4e6f214a3f794b1991713c100665c750 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Two-Hybrid System Techniques
117 rdf:type schema:DefinedTerm
118 N543c9f7e625147c7a317fea8063225a8 rdf:first sg:person.07755274557.36
119 rdf:rest N031ddd40b0944d02a6ffaadd86bd159b
120 N561be497199a4488a4b50a410985fa36 schema:name nlm_unique_id
121 schema:value 101231976
122 rdf:type schema:PropertyValue
123 N5658d29d302d41db98ff2d4cddbc64ed rdf:first sg:person.01037275306.68
124 rdf:rest N087c33119c184df4b286e75d567a2a43
125 N670a026951874a1fbc7a06d1cf387740 rdf:first sg:person.01326761272.35
126 rdf:rest N6a6d55ba80b040418c14aeb4dbed0750
127 N6a6d55ba80b040418c14aeb4dbed0750 rdf:first N1585c05209c345f89e373929eb88f7e9
128 rdf:rest N28c2cb34170c435c826f4b748a34a814
129 N7350c43a437a4a2b92c371aee3fd310b rdf:first sg:person.016361100057.04
130 rdf:rest Nd0ac2ace5f184c8bb6cf4c24f94c4cd2
131 N73b61eedcdc2426b88079e09325f7607 rdf:first sg:person.0656250576.21
132 rdf:rest N0b45ff4e124f4cf69a2f62e1db3b5635
133 N797ec86aec304642ae63cdda2fd225d1 rdf:first sg:person.0734673546.92
134 rdf:rest N07557d48b0944cc7861c61e1aecd208d
135 N7a577571774e4b37983b74d61eb7f22b schema:name dimensions_id
136 schema:value pub.1012238186
137 rdf:type schema:PropertyValue
138 N7acbd16a097c47a58b399745444936c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Protein Binding
140 rdf:type schema:DefinedTerm
141 Na19c574215e3465f8a669c39a0c04f36 schema:name pubmed_id
142 schema:value 23831759
143 rdf:type schema:PropertyValue
144 Na352b2314c2b424db501aefe667f791f rdf:first sg:person.01163167641.22
145 rdf:rest N0768797a89d6449fba1f281ebb6a4d67
146 Nb5c62de349024395b0049ec9d71909bd schema:name Springer Nature - SN SciGraph project
147 rdf:type schema:Organization
148 Nbe412ea800184da69450067687425384 schema:issueNumber 9
149 rdf:type schema:PublicationIssue
150 Nc0188707cdf54a368a25ff7f02a0178c rdf:first sg:person.0657733713.25
151 rdf:rest N7350c43a437a4a2b92c371aee3fd310b
152 Nc4f7551effb947cb84018b8372d793f3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Protein Interaction Mapping
154 rdf:type schema:DefinedTerm
155 Nc8f9292b2663409ea53deecd96b8069f schema:name readcube_id
156 schema:value 3a4e6eee2d39c0bf11909ea6982103544f7f3b2988f9b32db56b55f4cfa1ad3b
157 rdf:type schema:PropertyValue
158 Nca0b3775a1f040b099885e0358303764 schema:volumeNumber 9
159 rdf:type schema:PublicationVolume
160 Ncfcf4b48450b4b10ae4a055de6354e2c rdf:first sg:person.0713060160.72
161 rdf:rest N43ffa52301c64b67abc3e9e06c4de648
162 Nd0533f94f915465fa1c4b3474ed3f6dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name ATP-Binding Cassette Transporters
164 rdf:type schema:DefinedTerm
165 Nd0ac2ace5f184c8bb6cf4c24f94c4cd2 rdf:first sg:person.01326676141.60
166 rdf:rest N27e0611457da4a09896a65e1f6b5cbb9
167 Ne7e30ac3ebcb4e4a9f77d32145636f0c rdf:first sg:person.01341434131.39
168 rdf:rest Nc0188707cdf54a368a25ff7f02a0178c
169 Neb80fbcf06b547fbaabc3feaa9f02f63 rdf:first sg:person.0717603572.05
170 rdf:rest N73b61eedcdc2426b88079e09325f7607
171 Nef26dc56885e4c9ea1cd19ccd1193dc0 schema:name doi
172 schema:value 10.1038/nchembio.1293
173 rdf:type schema:PropertyValue
174 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
175 schema:name Biological Sciences
176 rdf:type schema:DefinedTerm
177 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
178 schema:name Biochemistry and Cell Biology
179 rdf:type schema:DefinedTerm
180 sg:grant.2514484 http://pending.schema.org/fundedItem sg:pub.10.1038/nchembio.1293
181 rdf:type schema:MonetaryGrant
182 sg:grant.2519020 http://pending.schema.org/fundedItem sg:pub.10.1038/nchembio.1293
183 rdf:type schema:MonetaryGrant
184 sg:journal.1327431 schema:issn 1552-4450
185 1552-4469
186 schema:name Nature Chemical Biology
187 rdf:type schema:Periodical
188 sg:person.01034032172.28 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
189 schema:familyName Darowski
190 schema:givenName Katelyn D
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034032172.28
192 rdf:type schema:Person
193 sg:person.01037275306.68 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
194 schema:familyName Hanif
195 schema:givenName Asad
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01037275306.68
197 rdf:type schema:Person
198 sg:person.01076304272.13 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
199 schema:familyName Yu
200 schema:givenName Analyn R
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076304272.13
202 rdf:type schema:Person
203 sg:person.01126012112.31 schema:affiliation https://www.grid.ac/institutes/grid.239585.0
204 schema:familyName Balderes
205 schema:givenName Dina
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126012112.31
207 rdf:type schema:Person
208 sg:person.01132056571.21 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
209 schema:familyName Greenblatt
210 schema:givenName Jack F
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132056571.21
212 rdf:type schema:Person
213 sg:person.01133113243.47 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
214 schema:familyName Shevelev
215 schema:givenName Igor
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133113243.47
217 rdf:type schema:Person
218 sg:person.01156503215.89 schema:affiliation https://www.grid.ac/institutes/grid.57926.3f
219 schema:familyName Graham
220 schema:givenName Chris
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156503215.89
222 rdf:type schema:Person
223 sg:person.01163167641.22 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
224 schema:familyName San Luis
225 schema:givenName Bryan-Joseph
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163167641.22
227 rdf:type schema:Person
228 sg:person.01260646072.07 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
229 schema:familyName Damjanovic
230 schema:givenName Dunja
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260646072.07
232 rdf:type schema:Person
233 sg:person.01263513605.20 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
234 schema:familyName Michaelis
235 schema:givenName Susan
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263513605.20
237 rdf:type schema:Person
238 sg:person.01326676141.60 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
239 schema:familyName Park
240 schema:givenName Hay-Oak
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326676141.60
242 rdf:type schema:Person
243 sg:person.01326761272.35 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
244 schema:familyName Wierzbicka
245 schema:givenName Marta
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326761272.35
247 rdf:type schema:Person
248 sg:person.01341434131.39 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
249 schema:familyName Zhang
250 schema:givenName Zhaolei
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341434131.39
252 rdf:type schema:Person
253 sg:person.016361100057.04 schema:affiliation https://www.grid.ac/institutes/grid.57926.3f
254 schema:familyName Babu
255 schema:givenName Mohan
256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016361100057.04
257 rdf:type schema:Person
258 sg:person.0575365050.38 schema:affiliation https://www.grid.ac/institutes/grid.239585.0
259 schema:familyName Sturley
260 schema:givenName Stephen L
261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575365050.38
262 rdf:type schema:Person
263 sg:person.0656250576.21 schema:affiliation https://www.grid.ac/institutes/grid.57926.3f
264 schema:familyName Jessulat
265 schema:givenName Matthew
266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656250576.21
267 rdf:type schema:Person
268 sg:person.0657733713.25 schema:affiliation https://www.grid.ac/institutes/grid.266539.d
269 schema:familyName Paumi
270 schema:givenName Christian M
271 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657733713.25
272 rdf:type schema:Person
273 sg:person.0713060160.72 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
274 schema:familyName Chuk
275 schema:givenName Matthew
276 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713060160.72
277 rdf:type schema:Person
278 sg:person.0717603572.05 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
279 schema:familyName Wong
280 schema:givenName Victoria
281 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717603572.05
282 rdf:type schema:Person
283 sg:person.0734673546.92 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
284 schema:familyName Jin
285 schema:givenName Ke
286 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734673546.92
287 rdf:type schema:Person
288 sg:person.0757201257.74 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
289 schema:familyName Stagljar
290 schema:givenName Igor
291 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757201257.74
292 rdf:type schema:Person
293 sg:person.0761173360.61 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
294 schema:familyName Snider
295 schema:givenName Jamie
296 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761173360.61
297 rdf:type schema:Person
298 sg:person.0762055672.24 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
299 schema:familyName Lee
300 schema:givenName Mid Eum
301 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762055672.24
302 rdf:type schema:Person
303 sg:person.07755274557.36 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
304 schema:familyName Boone
305 schema:givenName Charles
306 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07755274557.36
307 rdf:type schema:Person
308 sg:pub.10.1007/978-1-59745-540-4_11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028556580
309 https://doi.org/10.1007/978-1-59745-540-4_11
310 rdf:type schema:CreativeWork
311 sg:pub.10.1007/s00018-003-3336-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003175515
312 https://doi.org/10.1007/s00018-003-3336-9
313 rdf:type schema:CreativeWork
314 sg:pub.10.1007/s00232-009-9173-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004219036
315 https://doi.org/10.1007/s00232-009-9173-5
316 rdf:type schema:CreativeWork
317 sg:pub.10.1007/s00709-011-0360-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001106424
318 https://doi.org/10.1007/s00709-011-0360-8
319 rdf:type schema:CreativeWork
320 sg:pub.10.1023/a:1012866803188 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033933064
321 https://doi.org/10.1023/a:1012866803188
322 rdf:type schema:CreativeWork
323 sg:pub.10.1038/75556 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044135237
324 https://doi.org/10.1038/75556
325 rdf:type schema:CreativeWork
326 sg:pub.10.1038/nature00935 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015995329
327 https://doi.org/10.1038/nature00935
328 rdf:type schema:CreativeWork
329 sg:pub.10.1038/nature02046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016490499
330 https://doi.org/10.1038/nature02046
331 rdf:type schema:CreativeWork
332 sg:pub.10.1038/nbt0102-87 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007758048
333 https://doi.org/10.1038/nbt0102-87
334 rdf:type schema:CreativeWork
335 sg:pub.10.1038/nprot.2010.83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030643472
336 https://doi.org/10.1038/nprot.2010.83
337 rdf:type schema:CreativeWork
338 sg:pub.10.1038/nrd1984 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042314065
339 https://doi.org/10.1038/nrd1984
340 rdf:type schema:CreativeWork
341 sg:pub.10.1186/1471-2164-11-177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038532952
342 https://doi.org/10.1186/1471-2164-11-177
343 rdf:type schema:CreativeWork
344 https://app.dimensions.ai/details/publication/pub.1074804462 schema:CreativeWork
345 https://doi.org/10.1002/(sici)1097-0061(199807)14:10<953::aid-yea293>3.0.co;2-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1026465198
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1002/j.1460-2075.1994.tb06627.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1082624347
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1002/yea.1504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029234017
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1002/yea.320110704 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013534752
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1016/j.febslet.2008.02.045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053349590
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1016/j.molcel.2007.03.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013829101
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1016/j.tibs.2009.06.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002350616
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1016/j.tplants.2008.02.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037891467
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1016/s0959-440x(03)00037-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008105088
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1016/s1097-2765(02)00496-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021038327
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1042/bj20110876 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029615519
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1073/pnas.93.21.11901 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039394498
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1073/pnas.93.6.2454 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029610922
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1073/pnas.95.9.5187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004450825
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1074/jbc.m204707200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005404483
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1074/jbc.m205052200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019295918
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1074/jbc.m300568200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051294346
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1074/jbc.m302760200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010968773
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1074/jbc.m407600200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010151152
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1074/jbc.r900014200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005710627
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1091/mbc.e02-08-0501 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031889966
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1093/bioinformatics/bth123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044410072
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1093/bioinformatics/bth456 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046132302
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1093/nar/gkn665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047944503
392 rdf:type schema:CreativeWork
393 https://doi.org/10.1093/nar/gkp931 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031228115
394 rdf:type schema:CreativeWork
395 https://doi.org/10.1093/nar/gkq1116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042062806
396 rdf:type schema:CreativeWork
397 https://doi.org/10.1093/nar/gkr1029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037074957
398 rdf:type schema:CreativeWork
399 https://doi.org/10.1101/gad.1362105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012511978
400 rdf:type schema:CreativeWork
401 https://doi.org/10.1101/gr.1239303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052744398
402 rdf:type schema:CreativeWork
403 https://doi.org/10.1101/gr.gr-1649r schema:sameAs https://app.dimensions.ai/details/publication/pub.1060407558
404 rdf:type schema:CreativeWork
405 https://doi.org/10.1111/j.1600-0854.2004.00168.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1000089643
406 rdf:type schema:CreativeWork
407 https://doi.org/10.1128/cmr.00051-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041710938
408 rdf:type schema:CreativeWork
409 https://doi.org/10.1128/ec.2.3.588-598.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051708196
410 rdf:type schema:CreativeWork
411 https://doi.org/10.1128/mmbr.00020-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041712681
412 rdf:type schema:CreativeWork
413 https://doi.org/10.1146/annurev.genom.6.080604.162122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003790951
414 rdf:type schema:CreativeWork
415 https://doi.org/10.1161/circresaha.107.165324 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011246958
416 rdf:type schema:CreativeWork
417 https://doi.org/10.1534/genetics.111.130724 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027937620
418 rdf:type schema:CreativeWork
419 https://www.grid.ac/institutes/grid.17063.33 schema:alternateName University of Toronto
420 schema:name Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada.
421 Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
422 Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
423 Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
424 rdf:type schema:Organization
425 https://www.grid.ac/institutes/grid.21107.35 schema:alternateName Johns Hopkins University
426 schema:name Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
427 rdf:type schema:Organization
428 https://www.grid.ac/institutes/grid.239585.0 schema:alternateName Columbia University Medical Center
429 schema:name Department of Pediatrics, Columbia University Medical Center, New York, New York, USA.
430 rdf:type schema:Organization
431 https://www.grid.ac/institutes/grid.261331.4 schema:alternateName The Ohio State University
432 schema:name Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, USA.
433 Molecular Cellular Developmental Biology Program, The Ohio State University, Columbus, Ohio, USA.
434 rdf:type schema:Organization
435 https://www.grid.ac/institutes/grid.266539.d schema:alternateName University of Kentucky
436 schema:name Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky, USA.
437 rdf:type schema:Organization
438 https://www.grid.ac/institutes/grid.57926.3f schema:alternateName University of Regina
439 schema:name Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, Saskatchewan, Canada.
440 Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
441 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...