Co-assembly, spatiotemporal control and morphogenesis of a hybrid protein–peptide system View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-11

AUTHORS

Karla E. Inostroza-Brito, Estelle Collin, Orit Siton-Mendelson, Katherine H. Smith, Amàlia Monge-Marcet, Daniela S. Ferreira, Raúl Pérez Rodríguez, Matilde Alonso, José Carlos Rodríguez-Cabello, Rui L. Reis, Francesc Sagués, Lorenzo Botto, Ronit Bitton, Helena S. Azevedo, Alvaro Mata

ABSTRACT

Controlling molecular interactions between bioinspired molecules can enable the development of new materials with higher complexity and innovative properties. Here we report on a dynamic system that emerges from the conformational modification of an elastin-like protein by peptide amphiphiles and with the capacity to access, and be maintained in, non-equilibrium for substantial periods of time. The system enables the formation of a robust membrane that displays controlled assembly and disassembly capabilities, adhesion and sealing to surfaces, self-healing and the capability to undergo morphogenesis into tubular structures with high spatiotemporal control. We use advanced microscopy along with turbidity and spectroscopic measurements to investigate the mechanism of assembly and its relation to the distinctive membrane architecture and the resulting dynamic properties. Using cell-culture experiments with endothelial and adipose-derived stem cells, we demonstrate the potential of this system to generate complex bioactive scaffolds for applications such as tissue engineering. More... »

PAGES

897-904

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nchem.2349

DOI

http://dx.doi.org/10.1038/nchem.2349

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037888497

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26492010


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Human Umbilical Vein Endothelial Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microscopy, Electron, Scanning", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Morphogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Peptides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tissue Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tissue Scaffolds", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.5841.8", 
          "name": [
            "School of Engineering & Materials Science, Queen Mary University of London, London E1 4NS, UK", 
            "Nanotechnology Platform, Parc Cient\u00edfic de Barcelona, Barcelona 08028, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Inostroza-Brito", 
        "givenName": "Karla E.", 
        "id": "sg:person.01271442001.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271442001.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Queen Mary University of London", 
          "id": "https://www.grid.ac/institutes/grid.4868.2", 
          "name": [
            "School of Engineering & Materials Science, Queen Mary University of London, London E1 4NS, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Collin", 
        "givenName": "Estelle", 
        "id": "sg:person.0764464131.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764464131.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ben-Gurion University of the Negev", 
          "id": "https://www.grid.ac/institutes/grid.7489.2", 
          "name": [
            "Department of Chemical Engineering and the Ilze Katz, Institute for Nanoscale Science & Technology Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Siton-Mendelson", 
        "givenName": "Orit", 
        "id": "sg:person.0614151101.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614151101.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.5841.8", 
          "name": [
            "Nanotechnology Platform, Parc Cient\u00edfic de Barcelona, Barcelona 08028, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Smith", 
        "givenName": "Katherine H.", 
        "id": "sg:person.01141316365.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141316365.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.5841.8", 
          "name": [
            "Nanotechnology Platform, Parc Cient\u00edfic de Barcelona, Barcelona 08028, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Monge-Marcet", 
        "givenName": "Am\u00e0lia", 
        "id": "sg:person.0642373755.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642373755.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Minho", 
          "id": "https://www.grid.ac/institutes/grid.10328.38", 
          "name": [
            "School of Engineering & Materials Science, Queen Mary University of London, London E1 4NS, UK", 
            "3B's Research Group \u2013 Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimar\u00e3es 4805-017, Portugal", 
            "ICVS/3B's, PT Government Associate Laboratory, Guimar\u00e3es 4805-017, Portugal"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ferreira", 
        "givenName": "Daniela S.", 
        "id": "sg:person.0743347407.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743347407.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.5841.8", 
          "name": [
            "Nanotechnology Platform, Parc Cient\u00edfic de Barcelona, Barcelona 08028, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rodr\u00edguez", 
        "givenName": "Ra\u00fal P\u00e9rez", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Valladolid", 
          "id": "https://www.grid.ac/institutes/grid.5239.d", 
          "name": [
            "BIOFORGE Group, University of Valladolid, CIBER-BBN, Valladolid 47011, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alonso", 
        "givenName": "Matilde", 
        "id": "sg:person.01371773365.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371773365.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Valladolid", 
          "id": "https://www.grid.ac/institutes/grid.5239.d", 
          "name": [
            "BIOFORGE Group, University of Valladolid, CIBER-BBN, Valladolid 47011, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rodr\u00edguez-Cabello", 
        "givenName": "Jos\u00e9 Carlos", 
        "id": "sg:person.0614136303.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614136303.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Minho", 
          "id": "https://www.grid.ac/institutes/grid.10328.38", 
          "name": [
            "3B's Research Group \u2013 Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimar\u00e3es 4805-017, Portugal", 
            "ICVS/3B's, PT Government Associate Laboratory, Guimar\u00e3es 4805-017, Portugal"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Reis", 
        "givenName": "Rui L.", 
        "id": "sg:person.0655434203.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655434203.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.5841.8", 
          "name": [
            "Departament de Qu\u00edmica F\u00edsica, Universitat de Barcelona, Barcelona 08028, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sagu\u00e9s", 
        "givenName": "Francesc", 
        "id": "sg:person.01240726422.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240726422.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Queen Mary University of London", 
          "id": "https://www.grid.ac/institutes/grid.4868.2", 
          "name": [
            "School of Engineering & Materials Science, Queen Mary University of London, London E1 4NS, UK", 
            "Institute of Bioengineering, Queen Mary University of London, London E1 4NS, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Botto", 
        "givenName": "Lorenzo", 
        "id": "sg:person.01343416301.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343416301.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ben-Gurion University of the Negev", 
          "id": "https://www.grid.ac/institutes/grid.7489.2", 
          "name": [
            "Department of Chemical Engineering and the Ilze Katz, Institute for Nanoscale Science & Technology Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bitton", 
        "givenName": "Ronit", 
        "id": "sg:person.01165761267.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165761267.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Queen Mary University of London", 
          "id": "https://www.grid.ac/institutes/grid.4868.2", 
          "name": [
            "School of Engineering & Materials Science, Queen Mary University of London, London E1 4NS, UK", 
            "3B's Research Group \u2013 Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimar\u00e3es 4805-017, Portugal", 
            "ICVS/3B's, PT Government Associate Laboratory, Guimar\u00e3es 4805-017, Portugal", 
            "Institute of Bioengineering, Queen Mary University of London, London E1 4NS, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Azevedo", 
        "givenName": "Helena S.", 
        "id": "sg:person.01170654547.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170654547.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Queen Mary University of London", 
          "id": "https://www.grid.ac/institutes/grid.4868.2", 
          "name": [
            "School of Engineering & Materials Science, Queen Mary University of London, London E1 4NS, UK", 
            "Nanotechnology Platform, Parc Cient\u00edfic de Barcelona, Barcelona 08028, Spain", 
            "Institute of Bioengineering, Queen Mary University of London, London E1 4NS, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mata", 
        "givenName": "Alvaro", 
        "id": "sg:person.01326114165.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326114165.13"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/nchem.1921", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001088869", 
          "https://doi.org/10.1038/nchem.1921"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jmb.2009.06.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005185037"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c4tb00168k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005327314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1070821", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005920915"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2012.04.040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008507103"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nnano.2009.298", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008573360", 
          "https://doi.org/10.1038/nnano.2009.298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nnano.2009.298", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008573360", 
          "https://doi.org/10.1038/nnano.2009.298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cis.2009.05.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009770662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0001-8686(00)00032-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010662589"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.b.32950", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011588563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature11859", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013012985", 
          "https://doi.org/10.1038/nature11859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/b919452p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014325107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/b919452p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014325107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchem.113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014415764", 
          "https://doi.org/10.1038/nchem.113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchem.861", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017150289", 
          "https://doi.org/10.1038/nchem.861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchem.861", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017150289", 
          "https://doi.org/10.1038/nchem.861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/417308a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019594820", 
          "https://doi.org/10.1038/417308a"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/417308a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019594820", 
          "https://doi.org/10.1038/417308a"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mabi.201400419", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019805185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c4ra16593d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034530290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1163/156856207779996904", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034775940"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmat2496", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035352969", 
          "https://doi.org/10.1038/nmat2496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmat2496", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035352969", 
          "https://doi.org/10.1038/nmat2496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2011.11.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035966606"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/b923903k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037398456"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/b923903k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037398456"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp972167t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038328240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp972167t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038328240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/adfm.201101538", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039249794"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1063187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040112811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/anie.201107754", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040369653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2010.10.048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041832072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jsb.2010.06.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044101079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmat2778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044347284", 
          "https://doi.org/10.1038/nmat2778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmat2778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044347284", 
          "https://doi.org/10.1038/nmat2778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jmb.2010.05.060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044930907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c3bm60019j", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045598516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1233936", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045927994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmat3569", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046786919", 
          "https://doi.org/10.1038/nmat3569"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.a.35257", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047824683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/smll.201300254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051309391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1117096109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051472865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1521-1878(200008)22:8<753::aid-bies9>3.0.co;2-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052062791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c0sm01075h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053154705"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bm201436y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055222256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1154586", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062457505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1182767", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062461296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1234621", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062467999"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-11", 
    "datePublishedReg": "2015-11-01", 
    "description": "Controlling molecular interactions between bioinspired molecules can enable the development of new materials with higher complexity and innovative properties. Here we report on a dynamic system that emerges from the conformational modification of an elastin-like protein by peptide amphiphiles and with the capacity to access, and be maintained in, non-equilibrium for substantial periods of time. The system enables the formation of a robust membrane that displays controlled assembly and disassembly capabilities, adhesion and sealing to surfaces, self-healing and the capability to undergo morphogenesis into tubular structures with high spatiotemporal control. We use advanced microscopy along with turbidity and spectroscopic measurements to investigate the mechanism of assembly and its relation to the distinctive membrane architecture and the resulting dynamic properties. Using cell-culture experiments with endothelial and adipose-derived stem cells, we demonstrate the potential of this system to generate complex bioactive scaffolds for applications such as tissue engineering. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nchem.2349", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.3792562", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1041224", 
        "issn": [
          "1755-4330", 
          "1755-4349"
        ], 
        "name": "Nature Chemistry", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "11", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "7"
      }
    ], 
    "name": "Co-assembly, spatiotemporal control and morphogenesis of a hybrid protein\u2013peptide system", 
    "pagination": "897-904", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b47d2fcb50cef014fb9e4fb8b43bfd11f02c833a80525767a8f2ea6609f6e0c7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26492010"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101499734"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nchem.2349"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1037888497"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nchem.2349", 
      "https://app.dimensions.ai/details/publication/pub.1037888497"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8663_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/nchem.2349"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nchem.2349'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nchem.2349'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nchem.2349'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nchem.2349'


 

This table displays all metadata directly associated to this object as RDF triples.

349 TRIPLES      21 PREDICATES      77 URIs      29 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nchem.2349 schema:about N03b6d7be35cf4281b16922904d62557a
2 N07cbfed3b20645c0a8ce1bbef9981361
3 N09033156718b4010aac477fe46707477
4 N4fa20327229f495b8b776128986efa96
5 N5097f918b4ec48b489cd60ae992c1fc2
6 Na989a3e3a8be4c4db703f72e545af1ba
7 Ncfa6d8c98d30498fa37901816ce9d611
8 Ne2e6ee3e5ad44a6b92ea3a3f515996b4
9 anzsrc-for:06
10 anzsrc-for:0601
11 schema:author Nc01a4413b1f144cba2f3c9252036a3bf
12 schema:citation sg:pub.10.1038/417308a
13 sg:pub.10.1038/nature11859
14 sg:pub.10.1038/nchem.113
15 sg:pub.10.1038/nchem.1921
16 sg:pub.10.1038/nchem.861
17 sg:pub.10.1038/nmat2496
18 sg:pub.10.1038/nmat2778
19 sg:pub.10.1038/nmat3569
20 sg:pub.10.1038/nnano.2009.298
21 https://doi.org/10.1002/1521-1878(200008)22:8<753::aid-bies9>3.0.co;2-z
22 https://doi.org/10.1002/adfm.201101538
23 https://doi.org/10.1002/anie.201107754
24 https://doi.org/10.1002/jbm.a.35257
25 https://doi.org/10.1002/jbm.b.32950
26 https://doi.org/10.1002/mabi.201400419
27 https://doi.org/10.1002/smll.201300254
28 https://doi.org/10.1016/j.biomaterials.2010.10.048
29 https://doi.org/10.1016/j.biomaterials.2012.04.040
30 https://doi.org/10.1016/j.cis.2009.05.002
31 https://doi.org/10.1016/j.cub.2011.11.010
32 https://doi.org/10.1016/j.jmb.2009.06.019
33 https://doi.org/10.1016/j.jmb.2010.05.060
34 https://doi.org/10.1016/j.jsb.2010.06.012
35 https://doi.org/10.1016/s0001-8686(00)00032-4
36 https://doi.org/10.1021/bm201436y
37 https://doi.org/10.1021/jp972167t
38 https://doi.org/10.1039/b919452p
39 https://doi.org/10.1039/b923903k
40 https://doi.org/10.1039/c0sm01075h
41 https://doi.org/10.1039/c3bm60019j
42 https://doi.org/10.1039/c4ra16593d
43 https://doi.org/10.1039/c4tb00168k
44 https://doi.org/10.1073/pnas.1117096109
45 https://doi.org/10.1126/science.1063187
46 https://doi.org/10.1126/science.1070821
47 https://doi.org/10.1126/science.1154586
48 https://doi.org/10.1126/science.1182767
49 https://doi.org/10.1126/science.1233936
50 https://doi.org/10.1126/science.1234621
51 https://doi.org/10.1163/156856207779996904
52 schema:datePublished 2015-11
53 schema:datePublishedReg 2015-11-01
54 schema:description Controlling molecular interactions between bioinspired molecules can enable the development of new materials with higher complexity and innovative properties. Here we report on a dynamic system that emerges from the conformational modification of an elastin-like protein by peptide amphiphiles and with the capacity to access, and be maintained in, non-equilibrium for substantial periods of time. The system enables the formation of a robust membrane that displays controlled assembly and disassembly capabilities, adhesion and sealing to surfaces, self-healing and the capability to undergo morphogenesis into tubular structures with high spatiotemporal control. We use advanced microscopy along with turbidity and spectroscopic measurements to investigate the mechanism of assembly and its relation to the distinctive membrane architecture and the resulting dynamic properties. Using cell-culture experiments with endothelial and adipose-derived stem cells, we demonstrate the potential of this system to generate complex bioactive scaffolds for applications such as tissue engineering.
55 schema:genre research_article
56 schema:inLanguage en
57 schema:isAccessibleForFree true
58 schema:isPartOf N339ca1bc54f64e509aa6c75255203309
59 N458969b1b45f4b5f8ca1d0790c117326
60 sg:journal.1041224
61 schema:name Co-assembly, spatiotemporal control and morphogenesis of a hybrid protein–peptide system
62 schema:pagination 897-904
63 schema:productId N1e0b761b498a4d6fbbe1c061ecb4056b
64 N763b25c6904149cb8de9a036549f8826
65 N885669eec59c4f588bee0c8a04255692
66 Ndd383d42f0324299a3b1c9ea956c509c
67 Nea5db85ee77143aabb530283c0ffb408
68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037888497
69 https://doi.org/10.1038/nchem.2349
70 schema:sdDatePublished 2019-04-10T14:48
71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
72 schema:sdPublisher N02de8f9a36d247b88e543772189128fd
73 schema:url http://www.nature.com/articles/nchem.2349
74 sgo:license sg:explorer/license/
75 sgo:sdDataset articles
76 rdf:type schema:ScholarlyArticle
77 N02de8f9a36d247b88e543772189128fd schema:name Springer Nature - SN SciGraph project
78 rdf:type schema:Organization
79 N03b6d7be35cf4281b16922904d62557a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Tissue Scaffolds
81 rdf:type schema:DefinedTerm
82 N07cbfed3b20645c0a8ce1bbef9981361 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Humans
84 rdf:type schema:DefinedTerm
85 N088bcf84727045c5854bdc957249f127 rdf:first sg:person.01165761267.78
86 rdf:rest Nd3dfc6c7ebd54bd091e998c61bfcbd3e
87 N09033156718b4010aac477fe46707477 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Proteins
89 rdf:type schema:DefinedTerm
90 N1e0b761b498a4d6fbbe1c061ecb4056b schema:name doi
91 schema:value 10.1038/nchem.2349
92 rdf:type schema:PropertyValue
93 N33466e862a014f91af478c78ae6082ef rdf:first sg:person.01240726422.00
94 rdf:rest N69ba7546b3a54cc49964a532677af06a
95 N339ca1bc54f64e509aa6c75255203309 schema:volumeNumber 7
96 rdf:type schema:PublicationVolume
97 N34c7436a4fee46a790f307f8f7f48776 rdf:first sg:person.01371773365.70
98 rdf:rest Nf0e6c2d9669d44bcb4a44d9a975ba419
99 N428e1a63673c40fea3d62fe94aabc959 rdf:first sg:person.0642373755.49
100 rdf:rest N678677c863794f59b83bfa7f0406edb7
101 N458969b1b45f4b5f8ca1d0790c117326 schema:issueNumber 11
102 rdf:type schema:PublicationIssue
103 N4fa20327229f495b8b776128986efa96 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Human Umbilical Vein Endothelial Cells
105 rdf:type schema:DefinedTerm
106 N5097f918b4ec48b489cd60ae992c1fc2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Morphogenesis
108 rdf:type schema:DefinedTerm
109 N5ac19051e63c4a5fb776f5b13d84fc5d rdf:first sg:person.01141316365.95
110 rdf:rest N428e1a63673c40fea3d62fe94aabc959
111 N678677c863794f59b83bfa7f0406edb7 rdf:first sg:person.0743347407.20
112 rdf:rest Nc48b0e3d598145889f1a4e42a1c2309e
113 N69ba7546b3a54cc49964a532677af06a rdf:first sg:person.01343416301.64
114 rdf:rest N088bcf84727045c5854bdc957249f127
115 N763b25c6904149cb8de9a036549f8826 schema:name readcube_id
116 schema:value b47d2fcb50cef014fb9e4fb8b43bfd11f02c833a80525767a8f2ea6609f6e0c7
117 rdf:type schema:PropertyValue
118 N7668fd7e9c7c49f28d58d1d05b1e57bb rdf:first sg:person.01326114165.13
119 rdf:rest rdf:nil
120 N885669eec59c4f588bee0c8a04255692 schema:name nlm_unique_id
121 schema:value 101499734
122 rdf:type schema:PropertyValue
123 N91daf57acd124536af6bb53bfda336a2 schema:affiliation https://www.grid.ac/institutes/grid.5841.8
124 schema:familyName Rodríguez
125 schema:givenName Raúl Pérez
126 rdf:type schema:Person
127 N99ba261a77aa49ef9c40c534a1c75ebd rdf:first sg:person.0655434203.36
128 rdf:rest N33466e862a014f91af478c78ae6082ef
129 Na989a3e3a8be4c4db703f72e545af1ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Microscopy, Electron, Scanning
131 rdf:type schema:DefinedTerm
132 Nb982f249c0e347bd89031de542b78560 rdf:first sg:person.0764464131.10
133 rdf:rest Nc81346fc9f024cf199681f3a3d05125f
134 Nc01a4413b1f144cba2f3c9252036a3bf rdf:first sg:person.01271442001.44
135 rdf:rest Nb982f249c0e347bd89031de542b78560
136 Nc48b0e3d598145889f1a4e42a1c2309e rdf:first N91daf57acd124536af6bb53bfda336a2
137 rdf:rest N34c7436a4fee46a790f307f8f7f48776
138 Nc81346fc9f024cf199681f3a3d05125f rdf:first sg:person.0614151101.34
139 rdf:rest N5ac19051e63c4a5fb776f5b13d84fc5d
140 Ncfa6d8c98d30498fa37901816ce9d611 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Peptides
142 rdf:type schema:DefinedTerm
143 Nd3dfc6c7ebd54bd091e998c61bfcbd3e rdf:first sg:person.01170654547.49
144 rdf:rest N7668fd7e9c7c49f28d58d1d05b1e57bb
145 Ndd383d42f0324299a3b1c9ea956c509c schema:name pubmed_id
146 schema:value 26492010
147 rdf:type schema:PropertyValue
148 Ne2e6ee3e5ad44a6b92ea3a3f515996b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Tissue Engineering
150 rdf:type schema:DefinedTerm
151 Nea5db85ee77143aabb530283c0ffb408 schema:name dimensions_id
152 schema:value pub.1037888497
153 rdf:type schema:PropertyValue
154 Nf0e6c2d9669d44bcb4a44d9a975ba419 rdf:first sg:person.0614136303.19
155 rdf:rest N99ba261a77aa49ef9c40c534a1c75ebd
156 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
157 schema:name Biological Sciences
158 rdf:type schema:DefinedTerm
159 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
160 schema:name Biochemistry and Cell Biology
161 rdf:type schema:DefinedTerm
162 sg:grant.3792562 http://pending.schema.org/fundedItem sg:pub.10.1038/nchem.2349
163 rdf:type schema:MonetaryGrant
164 sg:journal.1041224 schema:issn 1755-4330
165 1755-4349
166 schema:name Nature Chemistry
167 rdf:type schema:Periodical
168 sg:person.01141316365.95 schema:affiliation https://www.grid.ac/institutes/grid.5841.8
169 schema:familyName Smith
170 schema:givenName Katherine H.
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141316365.95
172 rdf:type schema:Person
173 sg:person.01165761267.78 schema:affiliation https://www.grid.ac/institutes/grid.7489.2
174 schema:familyName Bitton
175 schema:givenName Ronit
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165761267.78
177 rdf:type schema:Person
178 sg:person.01170654547.49 schema:affiliation https://www.grid.ac/institutes/grid.4868.2
179 schema:familyName Azevedo
180 schema:givenName Helena S.
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170654547.49
182 rdf:type schema:Person
183 sg:person.01240726422.00 schema:affiliation https://www.grid.ac/institutes/grid.5841.8
184 schema:familyName Sagués
185 schema:givenName Francesc
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240726422.00
187 rdf:type schema:Person
188 sg:person.01271442001.44 schema:affiliation https://www.grid.ac/institutes/grid.5841.8
189 schema:familyName Inostroza-Brito
190 schema:givenName Karla E.
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271442001.44
192 rdf:type schema:Person
193 sg:person.01326114165.13 schema:affiliation https://www.grid.ac/institutes/grid.4868.2
194 schema:familyName Mata
195 schema:givenName Alvaro
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326114165.13
197 rdf:type schema:Person
198 sg:person.01343416301.64 schema:affiliation https://www.grid.ac/institutes/grid.4868.2
199 schema:familyName Botto
200 schema:givenName Lorenzo
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343416301.64
202 rdf:type schema:Person
203 sg:person.01371773365.70 schema:affiliation https://www.grid.ac/institutes/grid.5239.d
204 schema:familyName Alonso
205 schema:givenName Matilde
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371773365.70
207 rdf:type schema:Person
208 sg:person.0614136303.19 schema:affiliation https://www.grid.ac/institutes/grid.5239.d
209 schema:familyName Rodríguez-Cabello
210 schema:givenName José Carlos
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614136303.19
212 rdf:type schema:Person
213 sg:person.0614151101.34 schema:affiliation https://www.grid.ac/institutes/grid.7489.2
214 schema:familyName Siton-Mendelson
215 schema:givenName Orit
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614151101.34
217 rdf:type schema:Person
218 sg:person.0642373755.49 schema:affiliation https://www.grid.ac/institutes/grid.5841.8
219 schema:familyName Monge-Marcet
220 schema:givenName Amàlia
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642373755.49
222 rdf:type schema:Person
223 sg:person.0655434203.36 schema:affiliation https://www.grid.ac/institutes/grid.10328.38
224 schema:familyName Reis
225 schema:givenName Rui L.
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655434203.36
227 rdf:type schema:Person
228 sg:person.0743347407.20 schema:affiliation https://www.grid.ac/institutes/grid.10328.38
229 schema:familyName Ferreira
230 schema:givenName Daniela S.
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743347407.20
232 rdf:type schema:Person
233 sg:person.0764464131.10 schema:affiliation https://www.grid.ac/institutes/grid.4868.2
234 schema:familyName Collin
235 schema:givenName Estelle
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764464131.10
237 rdf:type schema:Person
238 sg:pub.10.1038/417308a schema:sameAs https://app.dimensions.ai/details/publication/pub.1019594820
239 https://doi.org/10.1038/417308a
240 rdf:type schema:CreativeWork
241 sg:pub.10.1038/nature11859 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013012985
242 https://doi.org/10.1038/nature11859
243 rdf:type schema:CreativeWork
244 sg:pub.10.1038/nchem.113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014415764
245 https://doi.org/10.1038/nchem.113
246 rdf:type schema:CreativeWork
247 sg:pub.10.1038/nchem.1921 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001088869
248 https://doi.org/10.1038/nchem.1921
249 rdf:type schema:CreativeWork
250 sg:pub.10.1038/nchem.861 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017150289
251 https://doi.org/10.1038/nchem.861
252 rdf:type schema:CreativeWork
253 sg:pub.10.1038/nmat2496 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035352969
254 https://doi.org/10.1038/nmat2496
255 rdf:type schema:CreativeWork
256 sg:pub.10.1038/nmat2778 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044347284
257 https://doi.org/10.1038/nmat2778
258 rdf:type schema:CreativeWork
259 sg:pub.10.1038/nmat3569 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046786919
260 https://doi.org/10.1038/nmat3569
261 rdf:type schema:CreativeWork
262 sg:pub.10.1038/nnano.2009.298 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008573360
263 https://doi.org/10.1038/nnano.2009.298
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1002/1521-1878(200008)22:8<753::aid-bies9>3.0.co;2-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1052062791
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1002/adfm.201101538 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039249794
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1002/anie.201107754 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040369653
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1002/jbm.a.35257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047824683
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1002/jbm.b.32950 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011588563
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1002/mabi.201400419 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019805185
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1002/smll.201300254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051309391
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1016/j.biomaterials.2010.10.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041832072
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1016/j.biomaterials.2012.04.040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008507103
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1016/j.cis.2009.05.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009770662
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1016/j.cub.2011.11.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035966606
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1016/j.jmb.2009.06.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005185037
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1016/j.jmb.2010.05.060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044930907
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1016/j.jsb.2010.06.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044101079
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1016/s0001-8686(00)00032-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010662589
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1021/bm201436y schema:sameAs https://app.dimensions.ai/details/publication/pub.1055222256
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1021/jp972167t schema:sameAs https://app.dimensions.ai/details/publication/pub.1038328240
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1039/b919452p schema:sameAs https://app.dimensions.ai/details/publication/pub.1014325107
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1039/b923903k schema:sameAs https://app.dimensions.ai/details/publication/pub.1037398456
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1039/c0sm01075h schema:sameAs https://app.dimensions.ai/details/publication/pub.1053154705
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1039/c3bm60019j schema:sameAs https://app.dimensions.ai/details/publication/pub.1045598516
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1039/c4ra16593d schema:sameAs https://app.dimensions.ai/details/publication/pub.1034530290
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1039/c4tb00168k schema:sameAs https://app.dimensions.ai/details/publication/pub.1005327314
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1073/pnas.1117096109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051472865
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1126/science.1063187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040112811
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1126/science.1070821 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005920915
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1126/science.1154586 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062457505
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1126/science.1182767 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062461296
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1126/science.1233936 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045927994
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1126/science.1234621 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062467999
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1163/156856207779996904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034775940
326 rdf:type schema:CreativeWork
327 https://www.grid.ac/institutes/grid.10328.38 schema:alternateName University of Minho
328 schema:name 3B's Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimarães 4805-017, Portugal
329 ICVS/3B's, PT Government Associate Laboratory, Guimarães 4805-017, Portugal
330 School of Engineering & Materials Science, Queen Mary University of London, London E1 4NS, UK
331 rdf:type schema:Organization
332 https://www.grid.ac/institutes/grid.4868.2 schema:alternateName Queen Mary University of London
333 schema:name 3B's Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Guimarães 4805-017, Portugal
334 ICVS/3B's, PT Government Associate Laboratory, Guimarães 4805-017, Portugal
335 Institute of Bioengineering, Queen Mary University of London, London E1 4NS, UK
336 Nanotechnology Platform, Parc Científic de Barcelona, Barcelona 08028, Spain
337 School of Engineering & Materials Science, Queen Mary University of London, London E1 4NS, UK
338 rdf:type schema:Organization
339 https://www.grid.ac/institutes/grid.5239.d schema:alternateName University of Valladolid
340 schema:name BIOFORGE Group, University of Valladolid, CIBER-BBN, Valladolid 47011, Spain
341 rdf:type schema:Organization
342 https://www.grid.ac/institutes/grid.5841.8 schema:alternateName University of Barcelona
343 schema:name Departament de Química Física, Universitat de Barcelona, Barcelona 08028, Spain
344 Nanotechnology Platform, Parc Científic de Barcelona, Barcelona 08028, Spain
345 School of Engineering & Materials Science, Queen Mary University of London, London E1 4NS, UK
346 rdf:type schema:Organization
347 https://www.grid.ac/institutes/grid.7489.2 schema:alternateName Ben-Gurion University of the Negev
348 schema:name Department of Chemical Engineering and the Ilze Katz, Institute for Nanoscale Science & Technology Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
349 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...