Friction forces position the neural anlage View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-04

AUTHORS

Michael Smutny, Zsuzsa Ákos, Silvia Grigolon, Shayan Shamipour, Verena Ruprecht, Daniel Čapek, Martin Behrndt, Ekaterina Papusheva, Masazumi Tada, Björn Hof, Tamás Vicsek, Guillaume Salbreux, Carl-Philipp Heisenberg

ABSTRACT

During embryonic development, mechanical forces are essential for cellular rearrangements driving tissue morphogenesis. Here, we show that in the early zebrafish embryo, friction forces are generated at the interface between anterior axial mesoderm (prechordal plate, ppl) progenitors migrating towards the animal pole and neurectoderm progenitors moving in the opposite direction towards the vegetal pole of the embryo. These friction forces lead to global rearrangement of cells within the neurectoderm and determine the position of the neural anlage. Using a combination of experiments and simulations, we show that this process depends on hydrodynamic coupling between neurectoderm and ppl as a result of E-cadherin-mediated adhesion between those tissues. Our data thus establish the emergence of friction forces at the interface between moving tissues as a critical force-generating process shaping the embryo. More... »

PAGES

306

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncb3492

DOI

http://dx.doi.org/10.1038/ncb3492

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1084128692

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28346437


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomechanical Phenomena", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cadherins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Communication", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Movement", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryo, Nonmammalian", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endoderm", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Friction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gastrulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrodynamics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mesoderm", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Biological", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Morphogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nervous System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neural Plate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Zebrafish", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Zebrafish Proteins", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute of Science and Technology Austria", 
          "id": "https://www.grid.ac/institutes/grid.33565.36", 
          "name": [
            "Institute of Science and Technology Austria, Am\u00a0Campus\u00a01, A-3400\u00a0Klosterneuburg, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Smutny", 
        "givenName": "Michael", 
        "id": "sg:person.0623757243.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623757243.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "E\u00f6tv\u00f6s Lor\u00e1nd University", 
          "id": "https://www.grid.ac/institutes/grid.5591.8", 
          "name": [
            "Department of Biological Physics, E\u00f6tv\u00f6s University, P\u00e1zm\u00e1ny P\u00e9ter\u00a0s\u00e9t\u00e1ny\u00a01A, Budapest\u00a0H-1117, Hungary"
          ], 
          "type": "Organization"
        }, 
        "familyName": "\u00c1kos", 
        "givenName": "Zsuzsa", 
        "id": "sg:person.0656027007.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656027007.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "The\u00a0Francis Crick Institute, 1\u00a0Midland Road, London\u00a0NW1\u00a01AT, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grigolon", 
        "givenName": "Silvia", 
        "id": "sg:person.07361443321.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07361443321.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Science and Technology Austria", 
          "id": "https://www.grid.ac/institutes/grid.33565.36", 
          "name": [
            "Institute of Science and Technology Austria, Am\u00a0Campus\u00a01, A-3400\u00a0Klosterneuburg, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shamipour", 
        "givenName": "Shayan", 
        "id": "sg:person.07444354353.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07444354353.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pompeu Fabra University", 
          "id": "https://www.grid.ac/institutes/grid.5612.0", 
          "name": [
            "Centre for Genomic Regulation (CRG), The\u00a0Barcelona Institute for Science and Technology, Dr.\u00a0Aiguader\u00a088, 08003\u00a0Barcelona, Spain", 
            "Universitat Pompeu Fabra (UPF), 08003\u00a0Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ruprecht", 
        "givenName": "Verena", 
        "id": "sg:person.01252767657.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252767657.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Science and Technology Austria", 
          "id": "https://www.grid.ac/institutes/grid.33565.36", 
          "name": [
            "Institute of Science and Technology Austria, Am\u00a0Campus\u00a01, A-3400\u00a0Klosterneuburg, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "\u010capek", 
        "givenName": "Daniel", 
        "id": "sg:person.011441655271.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011441655271.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Science and Technology Austria", 
          "id": "https://www.grid.ac/institutes/grid.33565.36", 
          "name": [
            "Institute of Science and Technology Austria, Am\u00a0Campus\u00a01, A-3400\u00a0Klosterneuburg, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Behrndt", 
        "givenName": "Martin", 
        "id": "sg:person.01335261344.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335261344.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Science and Technology Austria", 
          "id": "https://www.grid.ac/institutes/grid.33565.36", 
          "name": [
            "Institute of Science and Technology Austria, Am\u00a0Campus\u00a01, A-3400\u00a0Klosterneuburg, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Papusheva", 
        "givenName": "Ekaterina", 
        "id": "sg:person.01224070645.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224070645.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University College London", 
          "id": "https://www.grid.ac/institutes/grid.83440.3b", 
          "name": [
            "Department of Cell and Developmental Biology, University College London, Gower\u00a0Street, London\u00a0WC1E\u00a06BT, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tada", 
        "givenName": "Masazumi", 
        "id": "sg:person.01233733010.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233733010.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Science and Technology Austria", 
          "id": "https://www.grid.ac/institutes/grid.33565.36", 
          "name": [
            "Institute of Science and Technology Austria, Am\u00a0Campus\u00a01, A-3400\u00a0Klosterneuburg, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hof", 
        "givenName": "Bj\u00f6rn", 
        "id": "sg:person.01142245544.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142245544.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "E\u00f6tv\u00f6s Lor\u00e1nd University", 
          "id": "https://www.grid.ac/institutes/grid.5591.8", 
          "name": [
            "Department of Biological Physics, E\u00f6tv\u00f6s University, P\u00e1zm\u00e1ny P\u00e9ter\u00a0s\u00e9t\u00e1ny\u00a01A, Budapest\u00a0H-1117, Hungary"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vicsek", 
        "givenName": "Tam\u00e1s", 
        "id": "sg:person.01370021645.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370021645.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "The\u00a0Francis Crick Institute, 1\u00a0Midland Road, London\u00a0NW1\u00a01AT, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Salbreux", 
        "givenName": "Guillaume", 
        "id": "sg:person.012345044027.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012345044027.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Science and Technology Austria", 
          "id": "https://www.grid.ac/institutes/grid.33565.36", 
          "name": [
            "Institute of Science and Technology Austria, Am\u00a0Campus\u00a01, A-3400\u00a0Klosterneuburg, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heisenberg", 
        "givenName": "Carl-Philipp", 
        "id": "sg:person.0750434541.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750434541.99"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/350339a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001670301", 
          "https://doi.org/10.1038/350339a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1749-8104-9-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003203384", 
          "https://doi.org/10.1186/1749-8104-9-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb1705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006465517", 
          "https://doi.org/10.1038/ncb1705"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb3138", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008152624", 
          "https://doi.org/10.1038/ncb3138"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2013.05.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008263031"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ydbio.2005.04.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011794729"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)80720-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011803984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.devcel.2014.11.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013485553"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.95.17.9932", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015516992"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1224143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016124803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biosystems.2012.04.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016610639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/dvdy.24401", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016629841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature03952", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017307373", 
          "https://doi.org/10.1038/nature03952"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature03952", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017307373", 
          "https://doi.org/10.1038/nature03952"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/aja.1002030302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017782944"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.physrep.2012.03.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019647309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gene.1046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020734105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gene.1063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023272195"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gene.1063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023272195"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-cellbio-092910-154043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024464542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c4ib00115j", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024496238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0896-6273(02)00596-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025298287"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pbio.1000544", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026279790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/dev.034892", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027234563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1103/physreve.74.061908", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028240212"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1103/physreve.74.061908", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028240212"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7554/elife.01817", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028256696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/dbio.2000.0150", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029553395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/dbio.2000.0150", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029553395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/dev.00758", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033195161"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-cellbio-100109-104027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035108899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1205870109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035824546"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/dvdy.20057", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038287983"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/dev.01668", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039423098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/dev.01667", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040580253"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mod.2005.03.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042292289"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/dbio.1994.1212", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042776613"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature13070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044581435", 
          "https://doi.org/10.1038/nature13070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0177(2000)9999:9999<::aid-dvdy1052>3.0.co;2-k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045364601"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.devcel.2011.10.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048278530"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.matbio.2009.10.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048730810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/dvdy.1216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049052231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.1327", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050333416", 
          "https://doi.org/10.1038/nmeth.1327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(02)01135-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052617034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1534-5807(04)00027-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052639005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35011068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053242271", 
          "https://doi.org/10.1038/35011068"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35011068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053242271", 
          "https://doi.org/10.1038/35011068"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082460320", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.devcel.2017.01.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083849409"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-04", 
    "datePublishedReg": "2017-04-01", 
    "description": "During embryonic development, mechanical forces are essential for cellular rearrangements driving tissue morphogenesis. Here, we show that in the early zebrafish embryo, friction forces are generated at the interface between anterior axial mesoderm (prechordal plate, ppl) progenitors migrating towards the animal pole and neurectoderm progenitors moving in the opposite direction towards the vegetal pole of the embryo. These friction forces lead to global rearrangement of cells within the neurectoderm and determine the position of the neural anlage. Using a combination of experiments and simulations, we show that this process depends on hydrodynamic coupling between neurectoderm and ppl as a result of E-cadherin-mediated adhesion between those tissues. Our data thus establish the emergence of friction forces at the interface between moving tissues as a critical force-generating process shaping the\u00a0embryo.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ncb3492", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.3773822", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6188057", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6798244", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3794457", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1021344", 
        "issn": [
          "1465-7392", 
          "1476-4679"
        ], 
        "name": "Nature Cell Biology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "name": "Friction forces position the neural anlage", 
    "pagination": "306", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "91aeeb1de75c9aec8767d21813cbd7a38a00aef8e8f27f6686f81c38cd020d36"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28346437"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100890575"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ncb3492"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1084128692"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ncb3492", 
      "https://app.dimensions.ai/details/publication/pub.1084128692"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:57", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000427.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/ncb3492"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ncb3492'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ncb3492'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ncb3492'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ncb3492'


 

This table displays all metadata directly associated to this object as RDF triples.

385 TRIPLES      21 PREDICATES      91 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ncb3492 schema:about N09d7d0a405564e91b9c647be5a1987a4
2 N14fc81e4588b45c4a9a4a6dd07aeef93
3 N2b497d36d63d4d58bdbaf9fce9be70ed
4 N2c58a00f98014f1bb83e52b47c0f65fd
5 N345fe107f9b14724a8848ffbfb11ffa0
6 N41ba5b825d4343838ee5a5d8d06ac184
7 N439d240c1661442bb23bf751b9a97c22
8 N49354a814e8148b48e46cbd4542e56d2
9 N4a1b12c6e5514244bb45ad13f1295289
10 N536da33d1bdd4a08890fd2bac4842a43
11 Nb773ebc10cff40f1ad785db16de6d4af
12 Nb7aff9a523f8403f8342b09d9601ba1d
13 Nbadb42adadd54d949a46af6a9ccef1dc
14 Nc315333d7e8a4808a1906eec370672f9
15 Ndc5f3d6ccee54c11b1ec30d38ac72eb7
16 Ndd64e5ee7cab43049dc53b0ebb26d996
17 Necbee8dd685641a587f3c396e37b9de2
18 Nf45178e3a7cb45878691413b927fef78
19 anzsrc-for:06
20 anzsrc-for:0601
21 schema:author Ndd70a5cf535c4810bc098e8551839ef8
22 schema:citation sg:pub.10.1038/35011068
23 sg:pub.10.1038/350339a0
24 sg:pub.10.1038/nature03952
25 sg:pub.10.1038/nature13070
26 sg:pub.10.1038/ncb1705
27 sg:pub.10.1038/ncb3138
28 sg:pub.10.1038/nmeth.1327
29 sg:pub.10.1186/1749-8104-9-9
30 https://app.dimensions.ai/details/publication/pub.1082460320
31 https://doi.org/10.1002/1097-0177(2000)9999:9999<::aid-dvdy1052>3.0.co;2-k
32 https://doi.org/10.1002/aja.1002030302
33 https://doi.org/10.1002/dvdy.1216
34 https://doi.org/10.1002/dvdy.20057
35 https://doi.org/10.1002/dvdy.24401
36 https://doi.org/10.1002/gene.1046
37 https://doi.org/10.1002/gene.1063
38 https://doi.org/10.1006/dbio.1994.1212
39 https://doi.org/10.1006/dbio.2000.0150
40 https://doi.org/10.1016/j.biosystems.2012.04.003
41 https://doi.org/10.1016/j.cell.2013.05.008
42 https://doi.org/10.1016/j.devcel.2011.10.013
43 https://doi.org/10.1016/j.devcel.2014.11.003
44 https://doi.org/10.1016/j.devcel.2017.01.010
45 https://doi.org/10.1016/j.matbio.2009.10.002
46 https://doi.org/10.1016/j.mod.2005.03.008
47 https://doi.org/10.1016/j.physrep.2012.03.004
48 https://doi.org/10.1016/j.ydbio.2005.04.021
49 https://doi.org/10.1016/s0092-8674(00)80720-5
50 https://doi.org/10.1016/s0092-8674(02)01135-2
51 https://doi.org/10.1016/s0896-6273(02)00596-2
52 https://doi.org/10.1016/s1534-5807(04)00027-9
53 https://doi.org/10.1039/c4ib00115j
54 https://doi.org/10.1073/pnas.1205870109
55 https://doi.org/10.1073/pnas.95.17.9932
56 https://doi.org/10.1103/physreve.74.061908
57 https://doi.org/10.1126/science.1224143
58 https://doi.org/10.1146/annurev-cellbio-092910-154043
59 https://doi.org/10.1146/annurev-cellbio-100109-104027
60 https://doi.org/10.1242/dev.00758
61 https://doi.org/10.1242/dev.01667
62 https://doi.org/10.1242/dev.01668
63 https://doi.org/10.1242/dev.034892
64 https://doi.org/10.1371/journal.pbio.1000544
65 https://doi.org/10.7554/elife.01817
66 schema:datePublished 2017-04
67 schema:datePublishedReg 2017-04-01
68 schema:description During embryonic development, mechanical forces are essential for cellular rearrangements driving tissue morphogenesis. Here, we show that in the early zebrafish embryo, friction forces are generated at the interface between anterior axial mesoderm (prechordal plate, ppl) progenitors migrating towards the animal pole and neurectoderm progenitors moving in the opposite direction towards the vegetal pole of the embryo. These friction forces lead to global rearrangement of cells within the neurectoderm and determine the position of the neural anlage. Using a combination of experiments and simulations, we show that this process depends on hydrodynamic coupling between neurectoderm and ppl as a result of E-cadherin-mediated adhesion between those tissues. Our data thus establish the emergence of friction forces at the interface between moving tissues as a critical force-generating process shaping the embryo.
69 schema:genre research_article
70 schema:inLanguage en
71 schema:isAccessibleForFree true
72 schema:isPartOf N5e609812440f46189543cca690abf994
73 Ne062b459ceb940ce94f39080ffe084ac
74 sg:journal.1021344
75 schema:name Friction forces position the neural anlage
76 schema:pagination 306
77 schema:productId N981bcd486d9b41cba91b4af8b5903507
78 Nc16685f4c83f4ce4806fa7e55f4c4b66
79 Ndd7206bb705c4daea3a07282b3c42017
80 Neda6f6d59eca4733b10207a33fc4be72
81 Nef41d7ae206644bca848bf322449c0d7
82 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084128692
83 https://doi.org/10.1038/ncb3492
84 schema:sdDatePublished 2019-04-10T18:57
85 schema:sdLicense https://scigraph.springernature.com/explorer/license/
86 schema:sdPublisher Na032397a55b04c1e8bf6411a19de6ab8
87 schema:url https://www.nature.com/articles/ncb3492
88 sgo:license sg:explorer/license/
89 sgo:sdDataset articles
90 rdf:type schema:ScholarlyArticle
91 N0557149e2f734e69b3c355c9f018db40 rdf:first sg:person.012345044027.09
92 rdf:rest N69fd95a9796046e9bc4645fbcc70df7a
93 N09d7d0a405564e91b9c647be5a1987a4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Cell Communication
95 rdf:type schema:DefinedTerm
96 N14fc81e4588b45c4a9a4a6dd07aeef93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Endoderm
98 rdf:type schema:DefinedTerm
99 N2975aee377fc4803b5a0f6a581343002 rdf:first sg:person.011441655271.42
100 rdf:rest N7447e1b9f03c40d58be311029f99149a
101 N2b497d36d63d4d58bdbaf9fce9be70ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Cell Movement
103 rdf:type schema:DefinedTerm
104 N2c58a00f98014f1bb83e52b47c0f65fd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Cadherins
106 rdf:type schema:DefinedTerm
107 N32812c1d0cff41239d3ee998257a0ddc rdf:first sg:person.01370021645.17
108 rdf:rest N0557149e2f734e69b3c355c9f018db40
109 N345fe107f9b14724a8848ffbfb11ffa0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Zebrafish Proteins
111 rdf:type schema:DefinedTerm
112 N41ba5b825d4343838ee5a5d8d06ac184 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Nervous System
114 rdf:type schema:DefinedTerm
115 N439d240c1661442bb23bf751b9a97c22 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Neural Plate
117 rdf:type schema:DefinedTerm
118 N44dacd38a5364b4d94f010af4f68847e rdf:first sg:person.01252767657.62
119 rdf:rest N2975aee377fc4803b5a0f6a581343002
120 N49354a814e8148b48e46cbd4542e56d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Morphogenesis
122 rdf:type schema:DefinedTerm
123 N4a1b12c6e5514244bb45ad13f1295289 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Mesoderm
125 rdf:type schema:DefinedTerm
126 N536da33d1bdd4a08890fd2bac4842a43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Gastrulation
128 rdf:type schema:DefinedTerm
129 N5e609812440f46189543cca690abf994 schema:volumeNumber 19
130 rdf:type schema:PublicationVolume
131 N69fd95a9796046e9bc4645fbcc70df7a rdf:first sg:person.0750434541.99
132 rdf:rest rdf:nil
133 N7447e1b9f03c40d58be311029f99149a rdf:first sg:person.01335261344.05
134 rdf:rest N861145f08d984ce5852bfffa456c9983
135 N861145f08d984ce5852bfffa456c9983 rdf:first sg:person.01224070645.01
136 rdf:rest Ne97052db19d543efab410799fb9c7ff2
137 N94d842be0e244c88b2cd5940844893b1 rdf:first sg:person.07361443321.23
138 rdf:rest Nba86e788229c475f8f5d225d77f8971c
139 N981bcd486d9b41cba91b4af8b5903507 schema:name pubmed_id
140 schema:value 28346437
141 rdf:type schema:PropertyValue
142 Na032397a55b04c1e8bf6411a19de6ab8 schema:name Springer Nature - SN SciGraph project
143 rdf:type schema:Organization
144 Nb773ebc10cff40f1ad785db16de6d4af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Friction
146 rdf:type schema:DefinedTerm
147 Nb7aff9a523f8403f8342b09d9601ba1d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Embryo, Nonmammalian
149 rdf:type schema:DefinedTerm
150 Nba86e788229c475f8f5d225d77f8971c rdf:first sg:person.07444354353.35
151 rdf:rest N44dacd38a5364b4d94f010af4f68847e
152 Nbadb42adadd54d949a46af6a9ccef1dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Models, Biological
154 rdf:type schema:DefinedTerm
155 Nc16685f4c83f4ce4806fa7e55f4c4b66 schema:name readcube_id
156 schema:value 91aeeb1de75c9aec8767d21813cbd7a38a00aef8e8f27f6686f81c38cd020d36
157 rdf:type schema:PropertyValue
158 Nc315333d7e8a4808a1906eec370672f9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Animals
160 rdf:type schema:DefinedTerm
161 Ncb3159fb6f6c413ebdf36a4b58aa21d0 rdf:first sg:person.01142245544.98
162 rdf:rest N32812c1d0cff41239d3ee998257a0ddc
163 Ndc5f3d6ccee54c11b1ec30d38ac72eb7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Hydrodynamics
165 rdf:type schema:DefinedTerm
166 Ndd64e5ee7cab43049dc53b0ebb26d996 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Mutation
168 rdf:type schema:DefinedTerm
169 Ndd70a5cf535c4810bc098e8551839ef8 rdf:first sg:person.0623757243.83
170 rdf:rest Nf66eedaf47ae486cb156a4c87fb7133d
171 Ndd7206bb705c4daea3a07282b3c42017 schema:name doi
172 schema:value 10.1038/ncb3492
173 rdf:type schema:PropertyValue
174 Ne062b459ceb940ce94f39080ffe084ac schema:issueNumber 4
175 rdf:type schema:PublicationIssue
176 Ne97052db19d543efab410799fb9c7ff2 rdf:first sg:person.01233733010.97
177 rdf:rest Ncb3159fb6f6c413ebdf36a4b58aa21d0
178 Necbee8dd685641a587f3c396e37b9de2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Biomechanical Phenomena
180 rdf:type schema:DefinedTerm
181 Neda6f6d59eca4733b10207a33fc4be72 schema:name nlm_unique_id
182 schema:value 100890575
183 rdf:type schema:PropertyValue
184 Nef41d7ae206644bca848bf322449c0d7 schema:name dimensions_id
185 schema:value pub.1084128692
186 rdf:type schema:PropertyValue
187 Nf45178e3a7cb45878691413b927fef78 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Zebrafish
189 rdf:type schema:DefinedTerm
190 Nf66eedaf47ae486cb156a4c87fb7133d rdf:first sg:person.0656027007.10
191 rdf:rest N94d842be0e244c88b2cd5940844893b1
192 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
193 schema:name Biological Sciences
194 rdf:type schema:DefinedTerm
195 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
196 schema:name Biochemistry and Cell Biology
197 rdf:type schema:DefinedTerm
198 sg:grant.3773822 http://pending.schema.org/fundedItem sg:pub.10.1038/ncb3492
199 rdf:type schema:MonetaryGrant
200 sg:grant.3794457 http://pending.schema.org/fundedItem sg:pub.10.1038/ncb3492
201 rdf:type schema:MonetaryGrant
202 sg:grant.6188057 http://pending.schema.org/fundedItem sg:pub.10.1038/ncb3492
203 rdf:type schema:MonetaryGrant
204 sg:grant.6798244 http://pending.schema.org/fundedItem sg:pub.10.1038/ncb3492
205 rdf:type schema:MonetaryGrant
206 sg:journal.1021344 schema:issn 1465-7392
207 1476-4679
208 schema:name Nature Cell Biology
209 rdf:type schema:Periodical
210 sg:person.01142245544.98 schema:affiliation https://www.grid.ac/institutes/grid.33565.36
211 schema:familyName Hof
212 schema:givenName Björn
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142245544.98
214 rdf:type schema:Person
215 sg:person.011441655271.42 schema:affiliation https://www.grid.ac/institutes/grid.33565.36
216 schema:familyName Čapek
217 schema:givenName Daniel
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011441655271.42
219 rdf:type schema:Person
220 sg:person.01224070645.01 schema:affiliation https://www.grid.ac/institutes/grid.33565.36
221 schema:familyName Papusheva
222 schema:givenName Ekaterina
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224070645.01
224 rdf:type schema:Person
225 sg:person.01233733010.97 schema:affiliation https://www.grid.ac/institutes/grid.83440.3b
226 schema:familyName Tada
227 schema:givenName Masazumi
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233733010.97
229 rdf:type schema:Person
230 sg:person.012345044027.09 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
231 schema:familyName Salbreux
232 schema:givenName Guillaume
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012345044027.09
234 rdf:type schema:Person
235 sg:person.01252767657.62 schema:affiliation https://www.grid.ac/institutes/grid.5612.0
236 schema:familyName Ruprecht
237 schema:givenName Verena
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252767657.62
239 rdf:type schema:Person
240 sg:person.01335261344.05 schema:affiliation https://www.grid.ac/institutes/grid.33565.36
241 schema:familyName Behrndt
242 schema:givenName Martin
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335261344.05
244 rdf:type schema:Person
245 sg:person.01370021645.17 schema:affiliation https://www.grid.ac/institutes/grid.5591.8
246 schema:familyName Vicsek
247 schema:givenName Tamás
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370021645.17
249 rdf:type schema:Person
250 sg:person.0623757243.83 schema:affiliation https://www.grid.ac/institutes/grid.33565.36
251 schema:familyName Smutny
252 schema:givenName Michael
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623757243.83
254 rdf:type schema:Person
255 sg:person.0656027007.10 schema:affiliation https://www.grid.ac/institutes/grid.5591.8
256 schema:familyName Ákos
257 schema:givenName Zsuzsa
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656027007.10
259 rdf:type schema:Person
260 sg:person.07361443321.23 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
261 schema:familyName Grigolon
262 schema:givenName Silvia
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07361443321.23
264 rdf:type schema:Person
265 sg:person.07444354353.35 schema:affiliation https://www.grid.ac/institutes/grid.33565.36
266 schema:familyName Shamipour
267 schema:givenName Shayan
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07444354353.35
269 rdf:type schema:Person
270 sg:person.0750434541.99 schema:affiliation https://www.grid.ac/institutes/grid.33565.36
271 schema:familyName Heisenberg
272 schema:givenName Carl-Philipp
273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750434541.99
274 rdf:type schema:Person
275 sg:pub.10.1038/35011068 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053242271
276 https://doi.org/10.1038/35011068
277 rdf:type schema:CreativeWork
278 sg:pub.10.1038/350339a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001670301
279 https://doi.org/10.1038/350339a0
280 rdf:type schema:CreativeWork
281 sg:pub.10.1038/nature03952 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017307373
282 https://doi.org/10.1038/nature03952
283 rdf:type schema:CreativeWork
284 sg:pub.10.1038/nature13070 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044581435
285 https://doi.org/10.1038/nature13070
286 rdf:type schema:CreativeWork
287 sg:pub.10.1038/ncb1705 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006465517
288 https://doi.org/10.1038/ncb1705
289 rdf:type schema:CreativeWork
290 sg:pub.10.1038/ncb3138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008152624
291 https://doi.org/10.1038/ncb3138
292 rdf:type schema:CreativeWork
293 sg:pub.10.1038/nmeth.1327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050333416
294 https://doi.org/10.1038/nmeth.1327
295 rdf:type schema:CreativeWork
296 sg:pub.10.1186/1749-8104-9-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003203384
297 https://doi.org/10.1186/1749-8104-9-9
298 rdf:type schema:CreativeWork
299 https://app.dimensions.ai/details/publication/pub.1082460320 schema:CreativeWork
300 https://doi.org/10.1002/1097-0177(2000)9999:9999<::aid-dvdy1052>3.0.co;2-k schema:sameAs https://app.dimensions.ai/details/publication/pub.1045364601
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1002/aja.1002030302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017782944
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1002/dvdy.1216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049052231
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1002/dvdy.20057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038287983
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1002/dvdy.24401 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016629841
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1002/gene.1046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020734105
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1002/gene.1063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023272195
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1006/dbio.1994.1212 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042776613
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1006/dbio.2000.0150 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029553395
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1016/j.biosystems.2012.04.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016610639
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1016/j.cell.2013.05.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008263031
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1016/j.devcel.2011.10.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048278530
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1016/j.devcel.2014.11.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013485553
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1016/j.devcel.2017.01.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083849409
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1016/j.matbio.2009.10.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048730810
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1016/j.mod.2005.03.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042292289
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1016/j.physrep.2012.03.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019647309
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1016/j.ydbio.2005.04.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011794729
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1016/s0092-8674(00)80720-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011803984
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1016/s0092-8674(02)01135-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052617034
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1016/s0896-6273(02)00596-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025298287
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1016/s1534-5807(04)00027-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052639005
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1039/c4ib00115j schema:sameAs https://app.dimensions.ai/details/publication/pub.1024496238
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1073/pnas.1205870109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035824546
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1073/pnas.95.17.9932 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015516992
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1103/physreve.74.061908 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028240212
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1126/science.1224143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016124803
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1146/annurev-cellbio-092910-154043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024464542
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1146/annurev-cellbio-100109-104027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035108899
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1242/dev.00758 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033195161
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1242/dev.01667 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040580253
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1242/dev.01668 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039423098
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1242/dev.034892 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027234563
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1371/journal.pbio.1000544 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026279790
367 rdf:type schema:CreativeWork
368 https://doi.org/10.7554/elife.01817 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028256696
369 rdf:type schema:CreativeWork
370 https://www.grid.ac/institutes/grid.33565.36 schema:alternateName Institute of Science and Technology Austria
371 schema:name Institute of Science and Technology Austria, Am Campus 1, A-3400 Klosterneuburg, Austria
372 rdf:type schema:Organization
373 https://www.grid.ac/institutes/grid.451388.3 schema:alternateName The Francis Crick Institute
374 schema:name The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK
375 rdf:type schema:Organization
376 https://www.grid.ac/institutes/grid.5591.8 schema:alternateName Eötvös Loránd University
377 schema:name Department of Biological Physics, Eötvös University, Pázmány Péter sétány 1A, Budapest H-1117, Hungary
378 rdf:type schema:Organization
379 https://www.grid.ac/institutes/grid.5612.0 schema:alternateName Pompeu Fabra University
380 schema:name Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, 08003 Barcelona, Spain
381 Universitat Pompeu Fabra (UPF), 08003 Barcelona, Spain
382 rdf:type schema:Organization
383 https://www.grid.ac/institutes/grid.83440.3b schema:alternateName University College London
384 schema:name Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK
385 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...