Cyclin C surprises in tumour suppression View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-10-31

AUTHORS

Marianna Trakala, Marcos Malumbres

ABSTRACT

Despite the importance of cyclins and cyclin-dependent kinases (Cdks) in the control of cell division, the physiological role of many of these regulators remains unknown. Cyclin C and its associated kinases Cdk3, Cdk8 and Cdk19 are now shown to function as tumour suppressors in haematopoietic malignancies by inhibiting the Notch1 pathway. More... »

PAGES

1031-1033

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncb3055

DOI

http://dx.doi.org/10.1038/ncb3055

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030614793

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25358351


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