Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-09-26

AUTHORS

Lars Jakobsson, Claudio A. Franco, Katie Bentley, Russell T. Collins, Bas Ponsioen, Irene M. Aspalter, Ian Rosewell, Marta Busse, Gavin Thurston, Alexander Medvinsky, Stefan Schulte-Merker, Holger Gerhardt

ABSTRACT

Notch and vascular endothelial growth factor receptor (VEGFR) coordinates endothelial cells behaviour during angiogenesis sprouting although exactly how is uncertain. Endothelial cells dynamically compete for the leading position in a sprout through relative levels of Vegfr1 and Vegfr2 in a Notch dependent manner.

PAGES

943-953

Journal

TITLE

Nature Cell Biology

ISSUE

10

VOLUME

12

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncb2103

DOI

http://dx.doi.org/10.1038/ncb2103

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017225679

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20871601


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