Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-08-15

AUTHORS

Michael H. A. Schmitz, Michael Held, Veerle Janssens, James R. A. Hutchins, Otto Hudecz, Elitsa Ivanova, Jozef Goris, Laura Trinkle-Mulcahy, Angus I. Lamond, Ina Poser, Anthony A. Hyman, Karl Mechtler, Jan-Michael Peters, Daniel W. Gerlich

ABSTRACT

An RNAi screen of protein phosphatases identifies PP2A–B55α as the main mitotic exit phosphatase in human cells. After mitosis, PP2A–B55α depletion delays the reassembly of the nuclear envelope and Golgi and the decondensation of chromatin.

PAGES

886-893

Journal

TITLE

Nature Cell Biology

ISSUE

9

VOLUME

12

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncb2092

DOI

http://dx.doi.org/10.1038/ncb2092

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024640130

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20711181


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curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ncb2092'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ncb2092'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ncb2092'


 

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