Transmission and spreading of tauopathy in transgenic mouse brain View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-06-07

AUTHORS

Florence Clavaguera, Tristan Bolmont, R. Anthony Crowther, Dorothee Abramowski, Stephan Frank, Alphonse Probst, Graham Fraser, Anna K. Stalder, Martin Beibel, Matthias Staufenbiel, Mathias Jucker, Michel Goedert, Markus Tolnay

ABSTRACT

Intracellular tau inclusions, a hallmark of several neurodegenerative diseases, propagate in the brain in an unknown fashion. Brain extracts prepared from mice expressing mutated human tau injected into mice expressing wild-type human tau induce the formation and spread of wild-type human tau inclusions.

PAGES

909-913

Journal

TITLE

Nature Cell Biology

ISSUE

7

VOLUME

11

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncb1901

DOI

http://dx.doi.org/10.1038/ncb1901

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042538398

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19503072


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