S100 chemokines mediate bookmarking of premetastatic niches View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-12

AUTHORS

Shahin Rafii, David Lyden

ABSTRACT

Primary tumours release soluble factors, including VEGF-A, TGF and TNF, which induce expression of the chemokines S100A8 and S100A9 in the myeloid and endothelial cells within the lung before tumour metastasis. These chemokine-activated premetastatic niches support adhesion and invasion of disseminating malignant cells, thereby establishing a fertile habitat for metastatic tumours. More... »

PAGES

1321-1323

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncb1206-1321

DOI

http://dx.doi.org/10.1038/ncb1206-1321

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031446527

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17139281


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