Polar expeditions — provisioning the centrosome for mitosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-06

AUTHORS

Sarah P Blagden, David M Glover

ABSTRACT

It is now clear that both centrioles and their surrounding pericentriolar material (PCM) are capable of self-assembly. Whereas centrioles are normally duplicated during G1-S phase, PCM components may be loaded onto centrosomes in both a microtubule-dependent and -independent manner at all stages of the cell cycle. Centrosomes enlarge dramatically after mitotic entry, when both Aurora A and Polo-like kinases cooperate to recruit additional gamma-tubulin ring complexes and microtubule-associated proteins to assist spindle formation. More... »

PAGES

505-511

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ncb0603-505

DOI

http://dx.doi.org/10.1038/ncb0603-505

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1001395504

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12776127


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