Ontology type: schema:ScholarlyArticle Open Access: True
2008-06-22
AUTHORSDanwei Huangfu, René Maehr, Wenjun Guo, Astrid Eijkelenboom, Melinda Snitow, Alice E Chen, Douglas A Melton
ABSTRACTExisting methods for reprogramming somatic cells to 'induced pluripotent stem cells' are inefficient, with only a small fraction of the starting cell population becoming pluripotent. Working with mouse embryonic fibroblasts, Hunagfu et al. increase reprogramming efficiency by treatment with DNA methyltransferase and histone deacetylase inhibitors.
PAGES795-797
http://scigraph.springernature.com/pub.10.1038/nbt1418
DOIhttp://dx.doi.org/10.1038/nbt1418
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/18568017
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