The minimum information required for reporting a molecular interaction experiment (MIMIx) View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2007-08-08

AUTHORS

Sandra Orchard, Lukasz Salwinski, Samuel Kerrien, Luisa Montecchi-Palazzi, Matthias Oesterheld, Volker Stümpflen, Arnaud Ceol, Andrew Chatr-aryamontri, John Armstrong, Peter Woollard, John J Salama, Susan Moore, Jérôme Wojcik, Gary D Bader, Marc Vidal, Michael E Cusick, Mark Gerstein, Anne-Claude Gavin, Giulio Superti-Furga, Jack Greenblatt, Joel Bader, Peter Uetz, Mike Tyers, Pierre Legrain, Stan Fields, Nicola Mulder, Michael Gilson, Michael Niepmann, Lyle Burgoon, Javier De Las Rivas, Carlos Prieto, Victoria M Perreau, Chris Hogue, Hans-Werner Mewes, Rolf Apweiler, Ioannis Xenarios, David Eisenberg, Gianni Cesareni, Henning Hermjakob

ABSTRACT

A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data. More... »

PAGES

894-898

Journal

TITLE

Nature Biotechnology

ISSUE

8

VOLUME

25

Author Affiliations

  • European Molecular Biology Laboratory (EMBL) – European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK
  • UCLA–US Department of Energy Institute for Genomics & Proteomics, University of California, Los Angeles, California, USA
  • Institute for Bioinformatics, Forschungszentrum für Umwelt und Gesundheit – National Research Center for Environment and Health, Neuherberg, Germany
  • Department of Molecular Biology, University of Rome Tor Vergata, Rome, Italy
  • GlaxoSmithkline R&D, Stevenage, UK
  • Blueprint Initiative, Samuel Lunenfeld Research Institute, Ontario, Canada
  • National University of Singapore, Clinical Research Centre, Singapore
  • Merck Serono International S.A., Geneva, Switzerland
  • Banting and Best Department of Medical Research, University of Toronto, Ontario, Canada
  • Center for Cancer Systems Biology and Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
  • Molecular Biophysics and Biochemistry Department, Yale University, New Haven, Connecticut, USA
  • EMBL, Heidelberg, Germany
  • CeMM Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
  • Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA
  • Institute of Toxicology and Genetics, Leopoldshafen, Forschungszentrum Karlsruhe, Germany
  • Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
  • Commissariat à l'Energie Atomique, Institut de Biologie et de Technologie de Saclay, Gif sur Yvette, France
  • Howard Hughes Medical Institute Department of Genome Sciences & Medicine, University of Washington, Seattle, Washington, USA
  • Institute for Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
  • University of Maryland Biotechnology Institute, Rockville, Maryland, USA
  • University of Giessen, Germany
  • Toxicogenomic Informatics and Solutions, Lansing, Michigan, USA
  • Cancer Research Center (Centro de Investigación del Cancer, University of Salamanca and Consejo Superior de Investigaciones Científicas), Salamanca, Spain
  • Centre for Neuroscience, University of Melbourne, Victoria, Australia
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nbt1324

    DOI

    http://dx.doi.org/10.1038/nbt1324

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1032491066

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17687370


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