Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-03-24

AUTHORS

Van Trung Chu, Timm Weber, Benedikt Wefers, Wolfgang Wurst, Sandrine Sander, Klaus Rajewsky, Ralf Kühn

ABSTRACT

The efficiency of precise CRISPR/Cas9 genome editing is increased by inhibition of the nonhomologous end joining pathway.

PAGES

543-548

Journal

TITLE

Nature Biotechnology

ISSUE

5

VOLUME

33

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nbt.3198

    DOI

    http://dx.doi.org/10.1038/nbt.3198

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1008895789

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25803306


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