Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-03-24

AUTHORS

Van Trung Chu, Timm Weber, Benedikt Wefers, Wolfgang Wurst, Sandrine Sander, Klaus Rajewsky, Ralf Kühn

ABSTRACT

The efficiency of precise CRISPR/Cas9 genome editing is increased by inhibition of the nonhomologous end joining pathway.

PAGES

543-548

Journal

TITLE

Nature Biotechnology

ISSUE

5

VOLUME

33

Related Patents

  • Method Of Gene Editing Of Lignin Degrading Enzymes From Phanerocheate Chrysosporium By Crispr-Cas9 System And Use Of The Same
  • Gene Correction For X-Cgd In Hematopoietic Stem And Progenitor Cells
  • Regulatory Element Of An Arginine Decarboxylase Gene And Methods And Uses Thereof
  • Timing Of Logged Molecular Events
  • Site-Specific Dna Modification Using A Donor Dna Repair Template Having Tandem Repeat Sequences
  • Compositions And Methods For Enhancing Triplex And Nuclease-Based Gene Editing
  • Cas Variants For Gene Editing
  • Improved Eukaryotic Cells For Protein Manufacturing And Methods Of Making Them
  • Cas9 Proteins Including Ligand-Dependent Inteins
  • Editing Of Ccr5 Receptor Gene To Protect Against Hiv Infection
  • Dual Inhibition Of Ikk1 And Ikk2 For The Treatment Of Proliferative Diseases
  • Allele Editing And Applications Thereof
  • Targeted Modification Of Rat Genome
  • Nuclease Profiling System
  • Retinoic Acid Receptor Gamma Agonists To Attenuate Anthracycline-Induced Cardiotoxicity
  • Methods And Compositions For Enhanced Nuclease-Mediated Genome Modification And Reduced Off-Target Site Effects
  • Materials And Methods For Treatment Of Hereditary Haemochromatosis
  • Ubiquitin Variants And Uses Therof As 53bp1 Inhibitors
  • Adenosine Nucleobase Editors And Uses Thereof
  • Aav Delivery Of Nucleobase Editors
  • Materials And Methods For Treatment Of Primary Hyperoxaluria Type 1 (Ph1) And Other Alanine-Glyoxylate Aminotransferase (Agxt) Gene Related Conditions Or Disorders
  • Methods For Identifying A Target Site Of A Cas9 Nuclease
  • High Efficiency Base Editors Comprising Gam
  • Intracellular Genomic Transplant And Methods Of Therapy
  • Methods For Using Dna Repair For Cell Engineering
  • Methods And Compositions For Targeted Genetic Modification Using Paired Guide Rnas
  • Method For The Selection Of Cells Based On Crispr/Cas-Controlled Integration Of A Detectable Tag To A Target Protein
  • Systems And Methods For Increasing Efficiency Of Genome Editing
  • Engineered Transcription Activator-Like Effector (Tale) Domains And Uses Thereof
  • Viral Method For Producing Genetically Modified Cells
  • Adenosine Nucleobase Editors And Uses Thereof
  • Materials And Methods For Treatment Of Severe Combined Immunodeficiency (Scid) Or Omenn Syndrome
  • Novel Nucleic Acid Modifiers
  • Methods For Modulating Dna Repair Outcomes
  • Cas9 Proteins Including Ligand-Dependent Inteins
  • Materials And Methods For Treatment Of Hereditary Haemochromatosis
  • Barcoding Sequences For Identification Of Gene Expression
  • Novel Nucleic Acid Modifiers
  • System For Genome Editing
  • Methods And Compositions For The Targeted Modification Of A Mouse Embryonic Stem Cell Genome
  • Tumor Infiltrating Lymphocytes And Methods Of Therapy
  • Timing Of Logged Molecular Events
  • Methods For Modulating Dna Repair Outcomes
  • Tumor Infiltrating Lymphocytes And Methods Of Therapy
  • Nucleobase Editors Comprising Nucleic Acid Programmable Dna Binding Proteins
  • Cancer Vaccine
  • Timing Of Logged Molecular Events
  • Methods And Compositions For Homology Directed Repair Of Double Strand Breaks In Plant Cell Genomes
  • Methods And Compositions For Homology-Directed Repair Of Cas Endonuclease Mediated Double Strand Breaks
  • Materials And Methods For Treatment Of Early Onset Parkinson's Disease (Park1) And Other Synuclein, Alpha (Snca) Gene Related Conditions Or Disorders
  • Viral Methods Of Making Genetically Modified Cells
  • Nano/Micromotors For Active And Dynamic Intracellular Payload Delivery
  • Nucleobase Editors Comprising Nucleic Acid Programmable Dna Binding Proteins
  • Enhancing Endonuclease Based Gene Editing In Primary Cells
  • Switchable Cas9 Nucleases And Uses Thereof
  • Intracellular Genomic Transplant And Methods Of Therapy
  • Evaluation And Improvement Of Nuclease Cleavage Specificity
  • Barcodes For Identification Of Gene Expression
  • Dna-Pkcs Inhibitors For Increasing Genome Editing Efficiency
  • Delivery Of Negatively Charged Proteins Using Cationic Lipids
  • Cas Variants For Gene Editing
  • Compounds For Increasing Genome Editing Efficiency
  • Rescue Of Recombinant Adenoviruses By Crispr/Cas-Mediated In Vivo Terminal Resolution
  • Modified Cells And Methods Of Therapy
  • Materials And Methods For Treatment Of Severe Combined Immunodeficiency (Scid) Or Omenn Syndrome
  • Nucleobase Editors And Uses Thereof
  • Modified Cells And Methods Of Therapy
  • Tumor Infiltrating Lymphocytes And Methods Of Therapy
  • Switchable Cas9 Nucleases And Uses Thereof
  • Fusions Of Cas9 Domains And Nucleic Acid-Editing Domains
  • Compounds For Increasing Genome Editing Efficiency
  • Methods And Compositions For Nucleic Acid And Protein Payload Delivery
  • Delivery System For Functional Nucleases
  • Molecular State Machines
  • Method For Determining Homologous Recombination Repair Activity
  • Delivery Of Negatively Charged Proteins Using Cationic Lipids
  • Improvements In Or Relating To Dna Recombination
  • Adeno-Associated Viral Vectors For Gene Therapy
  • Novel Family Of Rna-Programmable Endonucleases And Their Uses In Genome Editing And Other Applications
  • Cas9 Variants And Uses Thereof
  • Targeted Modification Of Rat Genome
  • Timing Of Logged Molecular Events
  • Enhancing Endonuclease Based Gene Editing In Primary Cells
  • Compounds For Increasing Genome Editing Efficiency
  • Improved Gene Editing Based On Endonuclease In Primary Cells
  • Dual Inhibition Of Ikk1 And Ikk2 For The Treatment Of Proliferative Diseases
  • Directed Nucleic Acid Repair
  • Methods And Compositions For The Targeted Modification Of A Mouse Es Cell Genome
  • Nucleobase Editors And Uses Thereof
  • Novel Nucleic Acid Modifier
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nbt.3198

    DOI

    http://dx.doi.org/10.1038/nbt.3198

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1008895789

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25803306


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "author": [
          {
            "affiliation": {
              "alternateName": "Max-Delbr\u00fcck-Center for Molecular Medicine, Berlin, Germany", 
              "id": "http://www.grid.ac/institutes/grid.419491.0", 
              "name": [
                "Max-Delbr\u00fcck-Center for Molecular Medicine, Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chu", 
            "givenName": "Van Trung", 
            "id": "sg:person.0607166030.06", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607166030.06"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Max-Delbr\u00fcck-Center for Molecular Medicine, Berlin, Germany", 
              "id": "http://www.grid.ac/institutes/grid.419491.0", 
              "name": [
                "Max-Delbr\u00fcck-Center for Molecular Medicine, Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Weber", 
            "givenName": "Timm", 
            "id": "sg:person.01006746271.99", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006746271.99"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Deutsches Zentrum f\u00fcr Neurodegenerative Erkrankungen e.V., Munich, Germany", 
              "id": "http://www.grid.ac/institutes/grid.424247.3", 
              "name": [
                "Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health, Neuherberg, Germany", 
                "Deutsches Zentrum f\u00fcr Neurodegenerative Erkrankungen e.V., Munich, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wefers", 
            "givenName": "Benedikt", 
            "id": "sg:person.0742451576.65", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742451576.65"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Munich Cluster for Systems Neurology (SyNergy), Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Munich, Germany", 
              "id": "http://www.grid.ac/institutes/grid.5252.0", 
              "name": [
                "Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health, Neuherberg, Germany", 
                "Deutsches Zentrum f\u00fcr Neurodegenerative Erkrankungen e.V., Munich, Germany", 
                "Munich Cluster for Systems Neurology (SyNergy), Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Munich, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wurst", 
            "givenName": "Wolfgang", 
            "id": "sg:person.0723114325.33", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723114325.33"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Max-Delbr\u00fcck-Center for Molecular Medicine, Berlin, Germany", 
              "id": "http://www.grid.ac/institutes/grid.419491.0", 
              "name": [
                "Max-Delbr\u00fcck-Center for Molecular Medicine, Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sander", 
            "givenName": "Sandrine", 
            "id": "sg:person.0677042211.24", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677042211.24"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Max-Delbr\u00fcck-Center for Molecular Medicine, Berlin, Germany", 
              "id": "http://www.grid.ac/institutes/grid.419491.0", 
              "name": [
                "Max-Delbr\u00fcck-Center for Molecular Medicine, Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rajewsky", 
            "givenName": "Klaus", 
            "id": "sg:person.01100617445.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100617445.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Berlin Institute of Health, Berlin, Germany", 
              "id": "http://www.grid.ac/institutes/grid.484013.a", 
              "name": [
                "Max-Delbr\u00fcck-Center for Molecular Medicine, Berlin, Germany", 
                "Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health, Neuherberg, Germany", 
                "Berlin Institute of Health, Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "K\u00fchn", 
            "givenName": "Ralf", 
            "id": "sg:person.0615315017.46", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615315017.46"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/nmeth.1648", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035945498", 
              "https://doi.org/10.1038/nmeth.1648"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth1062", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022123114", 
              "https://doi.org/10.1038/nmeth1062"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm3659", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000099274", 
              "https://doi.org/10.1038/nrm3659"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2015-03-24", 
        "datePublishedReg": "2015-03-24", 
        "description": "The efficiency of precise CRISPR/Cas9 genome editing is increased by inhibition of the nonhomologous end joining pathway.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/nbt.3198", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.8018658", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1115214", 
            "issn": [
              "1087-0156", 
              "1546-1696"
            ], 
            "name": "Nature Biotechnology", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "5", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "33"
          }
        ], 
        "keywords": [
          "precise CRISPR/", 
          "homology-directed repair", 
          "precise gene editing", 
          "mammalian cells", 
          "genome editing", 
          "nonhomologous end", 
          "CRISPR/", 
          "gene editing", 
          "editing", 
          "pathway", 
          "cells", 
          "inhibition", 
          "repair", 
          "end", 
          "efficiency"
        ], 
        "name": "Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells", 
        "pagination": "543-548", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1008895789"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nbt.3198"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "25803306"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nbt.3198", 
          "https://app.dimensions.ai/details/publication/pub.1008895789"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-08-04T17:03", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_674.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/nbt.3198"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nbt.3198'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nbt.3198'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nbt.3198'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nbt.3198'


     

    This table displays all metadata directly associated to this object as RDF triples.

    138 TRIPLES      20 PREDICATES      41 URIs      32 LITERALS      7 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nbt.3198 schema:author N8e86c6956fa24ac5ad1451de1c6ba087
    2 schema:citation sg:pub.10.1038/nmeth.1648
    3 sg:pub.10.1038/nmeth1062
    4 sg:pub.10.1038/nrm3659
    5 schema:datePublished 2015-03-24
    6 schema:datePublishedReg 2015-03-24
    7 schema:description The efficiency of precise CRISPR/Cas9 genome editing is increased by inhibition of the nonhomologous end joining pathway.
    8 schema:genre article
    9 schema:isAccessibleForFree true
    10 schema:isPartOf N100f319ad0d448809c17c2d1ea583e03
    11 Ne65e8f7495b946a2b21b45d0fbe84064
    12 sg:journal.1115214
    13 schema:keywords CRISPR/
    14 cells
    15 editing
    16 efficiency
    17 end
    18 gene editing
    19 genome editing
    20 homology-directed repair
    21 inhibition
    22 mammalian cells
    23 nonhomologous end
    24 pathway
    25 precise CRISPR/
    26 precise gene editing
    27 repair
    28 schema:name Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
    29 schema:pagination 543-548
    30 schema:productId N1d993122e0e34cea86a9fadb97faad6f
    31 N410dbffb981f459b854467ce61e48850
    32 Nb87bdf5eaf7442c0a66f6766b5323772
    33 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008895789
    34 https://doi.org/10.1038/nbt.3198
    35 schema:sdDatePublished 2022-08-04T17:03
    36 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    37 schema:sdPublisher N56761137a00a451a8b82a9df39b533ba
    38 schema:url https://doi.org/10.1038/nbt.3198
    39 sgo:license sg:explorer/license/
    40 sgo:sdDataset articles
    41 rdf:type schema:ScholarlyArticle
    42 N100f319ad0d448809c17c2d1ea583e03 schema:issueNumber 5
    43 rdf:type schema:PublicationIssue
    44 N1d993122e0e34cea86a9fadb97faad6f schema:name dimensions_id
    45 schema:value pub.1008895789
    46 rdf:type schema:PropertyValue
    47 N27ab6aad784b40e6882e1556d4739de6 rdf:first sg:person.0723114325.33
    48 rdf:rest N4bb03e9355cf4cbd914cb4b9d1d1c556
    49 N410dbffb981f459b854467ce61e48850 schema:name doi
    50 schema:value 10.1038/nbt.3198
    51 rdf:type schema:PropertyValue
    52 N4bb03e9355cf4cbd914cb4b9d1d1c556 rdf:first sg:person.0677042211.24
    53 rdf:rest Nbc5a11eaf25c41bb99dc0a496e250865
    54 N56761137a00a451a8b82a9df39b533ba schema:name Springer Nature - SN SciGraph project
    55 rdf:type schema:Organization
    56 N6fc4e00f1fca4b64a022130a33d5fc59 rdf:first sg:person.01006746271.99
    57 rdf:rest N7fd8c1c69b5f4f3581df47e5738d48f2
    58 N7fd8c1c69b5f4f3581df47e5738d48f2 rdf:first sg:person.0742451576.65
    59 rdf:rest N27ab6aad784b40e6882e1556d4739de6
    60 N8e86c6956fa24ac5ad1451de1c6ba087 rdf:first sg:person.0607166030.06
    61 rdf:rest N6fc4e00f1fca4b64a022130a33d5fc59
    62 Nadeed8b35b0442f7b490673d00c6a706 rdf:first sg:person.0615315017.46
    63 rdf:rest rdf:nil
    64 Nb87bdf5eaf7442c0a66f6766b5323772 schema:name pubmed_id
    65 schema:value 25803306
    66 rdf:type schema:PropertyValue
    67 Nbc5a11eaf25c41bb99dc0a496e250865 rdf:first sg:person.01100617445.42
    68 rdf:rest Nadeed8b35b0442f7b490673d00c6a706
    69 Ne65e8f7495b946a2b21b45d0fbe84064 schema:volumeNumber 33
    70 rdf:type schema:PublicationVolume
    71 sg:grant.8018658 http://pending.schema.org/fundedItem sg:pub.10.1038/nbt.3198
    72 rdf:type schema:MonetaryGrant
    73 sg:journal.1115214 schema:issn 1087-0156
    74 1546-1696
    75 schema:name Nature Biotechnology
    76 schema:publisher Springer Nature
    77 rdf:type schema:Periodical
    78 sg:person.01006746271.99 schema:affiliation grid-institutes:grid.419491.0
    79 schema:familyName Weber
    80 schema:givenName Timm
    81 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006746271.99
    82 rdf:type schema:Person
    83 sg:person.01100617445.42 schema:affiliation grid-institutes:grid.419491.0
    84 schema:familyName Rajewsky
    85 schema:givenName Klaus
    86 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100617445.42
    87 rdf:type schema:Person
    88 sg:person.0607166030.06 schema:affiliation grid-institutes:grid.419491.0
    89 schema:familyName Chu
    90 schema:givenName Van Trung
    91 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607166030.06
    92 rdf:type schema:Person
    93 sg:person.0615315017.46 schema:affiliation grid-institutes:grid.484013.a
    94 schema:familyName Kühn
    95 schema:givenName Ralf
    96 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615315017.46
    97 rdf:type schema:Person
    98 sg:person.0677042211.24 schema:affiliation grid-institutes:grid.419491.0
    99 schema:familyName Sander
    100 schema:givenName Sandrine
    101 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677042211.24
    102 rdf:type schema:Person
    103 sg:person.0723114325.33 schema:affiliation grid-institutes:grid.5252.0
    104 schema:familyName Wurst
    105 schema:givenName Wolfgang
    106 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723114325.33
    107 rdf:type schema:Person
    108 sg:person.0742451576.65 schema:affiliation grid-institutes:grid.424247.3
    109 schema:familyName Wefers
    110 schema:givenName Benedikt
    111 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742451576.65
    112 rdf:type schema:Person
    113 sg:pub.10.1038/nmeth.1648 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035945498
    114 https://doi.org/10.1038/nmeth.1648
    115 rdf:type schema:CreativeWork
    116 sg:pub.10.1038/nmeth1062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022123114
    117 https://doi.org/10.1038/nmeth1062
    118 rdf:type schema:CreativeWork
    119 sg:pub.10.1038/nrm3659 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000099274
    120 https://doi.org/10.1038/nrm3659
    121 rdf:type schema:CreativeWork
    122 grid-institutes:grid.419491.0 schema:alternateName Max-Delbrück-Center for Molecular Medicine, Berlin, Germany
    123 schema:name Max-Delbrück-Center for Molecular Medicine, Berlin, Germany
    124 rdf:type schema:Organization
    125 grid-institutes:grid.424247.3 schema:alternateName Deutsches Zentrum für Neurodegenerative Erkrankungen e.V., Munich, Germany
    126 schema:name Deutsches Zentrum für Neurodegenerative Erkrankungen e.V., Munich, Germany
    127 Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
    128 rdf:type schema:Organization
    129 grid-institutes:grid.484013.a schema:alternateName Berlin Institute of Health, Berlin, Germany
    130 schema:name Berlin Institute of Health, Berlin, Germany
    131 Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
    132 Max-Delbrück-Center for Molecular Medicine, Berlin, Germany
    133 rdf:type schema:Organization
    134 grid-institutes:grid.5252.0 schema:alternateName Munich Cluster for Systems Neurology (SyNergy), Ludwig-Maximilians-Universität München, Munich, Germany
    135 schema:name Deutsches Zentrum für Neurodegenerative Erkrankungen e.V., Munich, Germany
    136 Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
    137 Munich Cluster for Systems Neurology (SyNergy), Ludwig-Maximilians-Universität München, Munich, Germany
    138 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...