Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-03-23

AUTHORS

Takeshi Maruyama, Stephanie K Dougan, Matthias C Truttmann, Angelina M Bilate, Jessica R Ingram, Hidde L Ploegh

ABSTRACT

The efficiency of homologous recombination-based Cas9 genome editing is increased by inhibiting non-homologous end joining.

PAGES

538-542

Journal

TITLE

Nature Biotechnology

ISSUE

5

VOLUME

33

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nbt.3190

    DOI

    http://dx.doi.org/10.1038/nbt.3190

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1017538548

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25798939


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