Absolute quantification of somatic DNA alterations in human cancer View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-04-29

AUTHORS

Scott L Carter, Kristian Cibulskis, Elena Helman, Aaron McKenna, Hui Shen, Travis Zack, Peter W Laird, Robert C Onofrio, Wendy Winckler, Barbara A Weir, Rameen Beroukhim, David Pellman, Douglas A Levine, Eric S Lander, Matthew Meyerson, Gad Getz

ABSTRACT

Tumors vary in their ratio of normal to cancerous cells and in their genomic copy number. Carter et al. describe an analytic method for inferring the purity and ploidy of a tumor sample, enabling longitudinal studies of subclonal mutations and tumor evolution.

PAGES

413-421

References to SciGraph publications

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  • Journal

    TITLE

    Nature Biotechnology

    ISSUE

    5

    VOLUME

    30

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nbt.2203

    DOI

    http://dx.doi.org/10.1038/nbt.2203

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1010515132

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22544022


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