Synthetic polymer coatings for long-term growth of human embryonic stem cells View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-06

AUTHORS

Luis G Villa-Diaz, Himabindu Nandivada, Jun Ding, Naiara C Nogueira-de-Souza, Paul H Krebsbach, K Sue O'Shea, Joerg Lahann, Gary D Smith

ABSTRACT

We report a fully defined synthetic polymer coating, poly[2-(methacryloyloxy)ethyl dimethyl-(3-sulfopropyl)ammonium hydroxide] (PMEDSAH), which sustains long-term human embryonic stem (hES) cell growth in several different culture media, including commercially available defined media. The development of a standardized, controllable and sustainable culture matrix for hES cells is an essential step in elucidating mechanisms that control hES cell behavior and in optimizing conditions for biomedical applications of hES cells. More... »

PAGES

581

Journal

TITLE

Nature Biotechnology

ISSUE

6

VOLUME

28

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nbt.1631

DOI

http://dx.doi.org/10.1038/nbt.1631

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017806200

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20512122


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