GREAT improves functional interpretation of cis-regulatory regions View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-05-02

AUTHORS

Cory Y McLean, Dave Bristor, Michael Hiller, Shoa L Clarke, Bruce T Schaar, Craig B Lowe, Aaron M Wenger, Gill Bejerano

ABSTRACT

ChIP-Seq data are usually analyzed with approaches developed for microarrays, which only consider binding events within a few kilobases of a gene. McLean et al. present an algorithm that takes into account more distant events, thereby improving functional annotation of regulatory regions.

PAGES

495-501

References to SciGraph publications

  • 2000-05. Gene Ontology: tool for the unification of biology in NATURE GENETICS
  • 2008-11-02. An integrated software system for analyzing ChIP-chip and ChIP-seq data in NATURE BIOTECHNOLOGY
  • 2009-12-13. Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells in NATURE GENETICS
  • 2001-06-01. Genetics of craniofacial development and malformation in NATURE REVIEWS GENETICS
  • 2008-11-16. Design and analysis of ChIP-seq experiments for DNA-binding proteins in NATURE BIOTECHNOLOGY
  • 2006-01. Microarray data analysis: from disarray to consolidation and consensus in NATURE REVIEWS GENETICS
  • 2003-02-01. Pattern formation: old models out on a limb in NATURE REVIEWS GENETICS
  • 2006-04-16. A distal enhancer and an ultraconserved exon are derived from a novel retroposon in NATURE
  • 2006-07-03. SRF is a nuclear repressor of Smad3-mediated TGF-β signaling in ONCOGENE
  • 2007-08. ChIP-seq: welcome to the new frontier in NATURE METHODS
  • 2001-02-01. Neural plate patterning: Upstream and downstream of the isthmic organizer in NATURE REVIEWS NEUROSCIENCE
  • 2009-01-04. PeakSeq enables systematic scoring of ChIP-seq experiments relative to controls in NATURE BIOTECHNOLOGY
  • 2006-11-13. cPath: open source software for collecting, storing, and querying biological pathways in BMC BIOINFORMATICS
  • 2007-06. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project in NATURE
  • 2009-02-01. ChIP-seq accurately predicts tissue-specific activity of enhancers in NATURE
  • 2008-03-23. Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids in NATURE GENETICS
  • 2009-09-08. ChIP–seq: advantages and challenges of a maturing technology in NATURE REVIEWS GENETICS
  • 2008-08-17. Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data in NATURE METHODS
  • Journal

    TITLE

    Nature Biotechnology

    ISSUE

    5

    VOLUME

    28

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nbt.1630

    DOI

    http://dx.doi.org/10.1038/nbt.1630

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1023421025

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20436461


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Chromatin Immunoprecipitation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Data Mining", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Databases, Genetic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "E1A-Associated p300 Protein", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genome", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genomics", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Jurkat Cells", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Protein Binding", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Regulatory Elements, Transcriptional", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Serum Response Factor", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Software", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Department of Computer Science, Stanford University, Stanford, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Computer Science, Stanford University, Stanford, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "McLean", 
            "givenName": "Cory Y", 
            "id": "sg:person.01127430011.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127430011.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Developmental Biology, Stanford University, Stanford, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Computer Science, Stanford University, Stanford, California, USA", 
                "Department of Developmental Biology, Stanford University, Stanford, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bristor", 
            "givenName": "Dave", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Developmental Biology, Stanford University, Stanford, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Developmental Biology, Stanford University, Stanford, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hiller", 
            "givenName": "Michael", 
            "id": "sg:person.0624077563.24", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624077563.24"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Genetics, Stanford University, Stanford, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Genetics, Stanford University, Stanford, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Clarke", 
            "givenName": "Shoa L", 
            "id": "sg:person.0776571131.70", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776571131.70"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Developmental Biology, Stanford University, Stanford, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Developmental Biology, Stanford University, Stanford, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schaar", 
            "givenName": "Bruce T", 
            "id": "sg:person.01304565413.15", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304565413.15"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.205975.c", 
              "name": [
                "Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lowe", 
            "givenName": "Craig B", 
            "id": "sg:person.01112215062.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112215062.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Computer Science, Stanford University, Stanford, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Computer Science, Stanford University, Stanford, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wenger", 
            "givenName": "Aaron M", 
            "id": "sg:person.012106407613.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012106407613.52"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Developmental Biology, Stanford University, Stanford, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Computer Science, Stanford University, Stanford, California, USA", 
                "Department of Developmental Biology, Stanford University, Stanford, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bejerano", 
            "givenName": "Gill", 
            "id": "sg:person.0677005046.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677005046.22"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/35076601", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040585763", 
              "https://doi.org/10.1038/35076601"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.496", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037625384", 
              "https://doi.org/10.1038/ng.496"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth0807-613", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051261645", 
              "https://doi.org/10.1038/nmeth0807-613"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature05874", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005913886", 
              "https://doi.org/10.1038/nature05874"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1518", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052955805", 
              "https://doi.org/10.1038/nbt.1518"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg1001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018812708", 
              "https://doi.org/10.1038/nrg1001"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg1749", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017349746", 
              "https://doi.org/10.1038/nrg1749"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature04696", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027944303", 
              "https://doi.org/10.1038/nature04696"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2105-7-497", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018353192", 
              "https://doi.org/10.1186/1471-2105-7-497"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35053516", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009729377", 
              "https://doi.org/10.1038/35053516"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1508", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028515757", 
              "https://doi.org/10.1038/nbt.1508"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature07730", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021031479", 
              "https://doi.org/10.1038/nature07730"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.1246", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037362623", 
              "https://doi.org/10.1038/nmeth.1246"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1209774", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044728705", 
              "https://doi.org/10.1038/sj.onc.1209774"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.113", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002249517", 
              "https://doi.org/10.1038/ng.113"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1505", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051483764", 
              "https://doi.org/10.1038/nbt.1505"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2641", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006115199", 
              "https://doi.org/10.1038/nrg2641"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/75556", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044135237", 
              "https://doi.org/10.1038/75556"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2010-05-02", 
        "datePublishedReg": "2010-05-02", 
        "description": "ChIP-Seq data are usually analyzed with approaches developed for microarrays, which only consider binding events within a few kilobases of a gene. McLean et al. present an algorithm that takes into account more distant events, thereby improving functional annotation of regulatory regions.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/nbt.1630", 
        "inLanguage": "en", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2527964", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1115214", 
            "issn": [
              "1087-0156", 
              "1546-1696"
            ], 
            "name": "Nature Biotechnology", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "5", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "28"
          }
        ], 
        "keywords": [
          "microarrays", 
          "events", 
          "ChIP-seq data", 
          "data", 
          "approach", 
          "kilobases", 
          "genes", 
          "account", 
          "distant events", 
          "functional annotation", 
          "annotation", 
          "regulatory region", 
          "region", 
          "functional interpretation", 
          "interpretation", 
          "cis-regulatory regions", 
          "algorithm", 
          "Great"
        ], 
        "name": "GREAT improves functional interpretation of cis-regulatory regions", 
        "pagination": "495-501", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1023421025"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nbt.1630"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "20436461"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nbt.1630", 
          "https://app.dimensions.ai/details/publication/pub.1023421025"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-05-10T09:57", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_504.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/nbt.1630"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nbt.1630'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nbt.1630'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nbt.1630'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nbt.1630'


     

    This table displays all metadata directly associated to this object as RDF triples.

    265 TRIPLES      22 PREDICATES      76 URIs      50 LITERALS      21 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nbt.1630 schema:about N130f9bc0e3d34c74ad81bb73667e4731
    2 N25abbf51a2ba4900b01194a54c299d39
    3 N6a7ec184c02e49e7a19339ace33d9f00
    4 N76130f0c150249c4a3dc89e3e89d65ec
    5 N7ada6da40d1740e3926ec4d131c4e9a8
    6 N7b39df56234849c6a0e06c1d3f91d09e
    7 N7b5dbcd4c77d462a89abfe70ce336e1b
    8 N8d318b4b9b5e4fee97f594b6bdcd8675
    9 N98b4b125dd034b999f2d13e79ce27cab
    10 Nbcd3b25f5e47413d8cb0c8166a0867bf
    11 Nd3c55c30409e4ee79cd0eb1a993aed84
    12 Nf0518c60f4e34079b325d5a4cb9da08a
    13 Nf65bbce23a6544a1a32ae50fd911a16b
    14 Nff11c041a86c40d59e2f38ded0b05897
    15 anzsrc-for:06
    16 anzsrc-for:0604
    17 schema:author Nd3244ac3e3fc41e8b21b29237c584eb2
    18 schema:citation sg:pub.10.1038/35053516
    19 sg:pub.10.1038/35076601
    20 sg:pub.10.1038/75556
    21 sg:pub.10.1038/nature04696
    22 sg:pub.10.1038/nature05874
    23 sg:pub.10.1038/nature07730
    24 sg:pub.10.1038/nbt.1505
    25 sg:pub.10.1038/nbt.1508
    26 sg:pub.10.1038/nbt.1518
    27 sg:pub.10.1038/ng.113
    28 sg:pub.10.1038/ng.496
    29 sg:pub.10.1038/nmeth.1246
    30 sg:pub.10.1038/nmeth0807-613
    31 sg:pub.10.1038/nrg1001
    32 sg:pub.10.1038/nrg1749
    33 sg:pub.10.1038/nrg2641
    34 sg:pub.10.1038/sj.onc.1209774
    35 sg:pub.10.1186/1471-2105-7-497
    36 schema:datePublished 2010-05-02
    37 schema:datePublishedReg 2010-05-02
    38 schema:description ChIP-Seq data are usually analyzed with approaches developed for microarrays, which only consider binding events within a few kilobases of a gene. McLean et al. present an algorithm that takes into account more distant events, thereby improving functional annotation of regulatory regions.
    39 schema:genre article
    40 schema:inLanguage en
    41 schema:isAccessibleForFree true
    42 schema:isPartOf N965df821068c43f99ff55dba4b1c6438
    43 Na022914de0cb4764a9f292695c38bc2c
    44 sg:journal.1115214
    45 schema:keywords ChIP-seq data
    46 Great
    47 account
    48 algorithm
    49 annotation
    50 approach
    51 cis-regulatory regions
    52 data
    53 distant events
    54 events
    55 functional annotation
    56 functional interpretation
    57 genes
    58 interpretation
    59 kilobases
    60 microarrays
    61 region
    62 regulatory region
    63 schema:name GREAT improves functional interpretation of cis-regulatory regions
    64 schema:pagination 495-501
    65 schema:productId N970b76423c7244c090c8c8b5eaa86361
    66 Na690e0f192ac49c4983b9ed9a4e30d5f
    67 Naca521ea683048debc02df6d8662bac4
    68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023421025
    69 https://doi.org/10.1038/nbt.1630
    70 schema:sdDatePublished 2022-05-10T09:57
    71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    72 schema:sdPublisher Na530c10bdfee476cb9df81cfe3dc7233
    73 schema:url https://doi.org/10.1038/nbt.1630
    74 sgo:license sg:explorer/license/
    75 sgo:sdDataset articles
    76 rdf:type schema:ScholarlyArticle
    77 N13018f3c8de44e5eb74f39f40fa52148 rdf:first N70bdffbc12ba41979c700746e303915b
    78 rdf:rest N8e2b33ed20814f5c845428c88f817532
    79 N130f9bc0e3d34c74ad81bb73667e4731 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    80 schema:name Chromatin Immunoprecipitation
    81 rdf:type schema:DefinedTerm
    82 N25abbf51a2ba4900b01194a54c299d39 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    83 schema:name E1A-Associated p300 Protein
    84 rdf:type schema:DefinedTerm
    85 N29ae3c9c48cb43c7b7f4268ee0d298b4 rdf:first sg:person.0677005046.22
    86 rdf:rest rdf:nil
    87 N321c6241dc5e468e9212fc8e083e44c7 rdf:first sg:person.01304565413.15
    88 rdf:rest N7374e29383e54b159c31979a972e1ca8
    89 N6a7ec184c02e49e7a19339ace33d9f00 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    90 schema:name Regulatory Elements, Transcriptional
    91 rdf:type schema:DefinedTerm
    92 N70bdffbc12ba41979c700746e303915b schema:affiliation grid-institutes:grid.168010.e
    93 schema:familyName Bristor
    94 schema:givenName Dave
    95 rdf:type schema:Person
    96 N7374e29383e54b159c31979a972e1ca8 rdf:first sg:person.01112215062.32
    97 rdf:rest Na267ddc7d3c64b3785caf8dfaf219a28
    98 N76130f0c150249c4a3dc89e3e89d65ec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    99 schema:name Animals
    100 rdf:type schema:DefinedTerm
    101 N7ada6da40d1740e3926ec4d131c4e9a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    102 schema:name Serum Response Factor
    103 rdf:type schema:DefinedTerm
    104 N7b39df56234849c6a0e06c1d3f91d09e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    105 schema:name Genomics
    106 rdf:type schema:DefinedTerm
    107 N7b5dbcd4c77d462a89abfe70ce336e1b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    108 schema:name Software
    109 rdf:type schema:DefinedTerm
    110 N80ef2fd5e02f4d6e8da42f8dc8447c46 rdf:first sg:person.0776571131.70
    111 rdf:rest N321c6241dc5e468e9212fc8e083e44c7
    112 N8d318b4b9b5e4fee97f594b6bdcd8675 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    113 schema:name Humans
    114 rdf:type schema:DefinedTerm
    115 N8e2b33ed20814f5c845428c88f817532 rdf:first sg:person.0624077563.24
    116 rdf:rest N80ef2fd5e02f4d6e8da42f8dc8447c46
    117 N965df821068c43f99ff55dba4b1c6438 schema:issueNumber 5
    118 rdf:type schema:PublicationIssue
    119 N970b76423c7244c090c8c8b5eaa86361 schema:name doi
    120 schema:value 10.1038/nbt.1630
    121 rdf:type schema:PropertyValue
    122 N98b4b125dd034b999f2d13e79ce27cab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    123 schema:name Jurkat Cells
    124 rdf:type schema:DefinedTerm
    125 Na022914de0cb4764a9f292695c38bc2c schema:volumeNumber 28
    126 rdf:type schema:PublicationVolume
    127 Na267ddc7d3c64b3785caf8dfaf219a28 rdf:first sg:person.012106407613.52
    128 rdf:rest N29ae3c9c48cb43c7b7f4268ee0d298b4
    129 Na530c10bdfee476cb9df81cfe3dc7233 schema:name Springer Nature - SN SciGraph project
    130 rdf:type schema:Organization
    131 Na690e0f192ac49c4983b9ed9a4e30d5f schema:name dimensions_id
    132 schema:value pub.1023421025
    133 rdf:type schema:PropertyValue
    134 Naca521ea683048debc02df6d8662bac4 schema:name pubmed_id
    135 schema:value 20436461
    136 rdf:type schema:PropertyValue
    137 Nbcd3b25f5e47413d8cb0c8166a0867bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    138 schema:name Mice
    139 rdf:type schema:DefinedTerm
    140 Nd3244ac3e3fc41e8b21b29237c584eb2 rdf:first sg:person.01127430011.25
    141 rdf:rest N13018f3c8de44e5eb74f39f40fa52148
    142 Nd3c55c30409e4ee79cd0eb1a993aed84 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    143 schema:name Databases, Genetic
    144 rdf:type schema:DefinedTerm
    145 Nf0518c60f4e34079b325d5a4cb9da08a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    146 schema:name Data Mining
    147 rdf:type schema:DefinedTerm
    148 Nf65bbce23a6544a1a32ae50fd911a16b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    149 schema:name Protein Binding
    150 rdf:type schema:DefinedTerm
    151 Nff11c041a86c40d59e2f38ded0b05897 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    152 schema:name Genome
    153 rdf:type schema:DefinedTerm
    154 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    155 schema:name Biological Sciences
    156 rdf:type schema:DefinedTerm
    157 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    158 schema:name Genetics
    159 rdf:type schema:DefinedTerm
    160 sg:grant.2527964 http://pending.schema.org/fundedItem sg:pub.10.1038/nbt.1630
    161 rdf:type schema:MonetaryGrant
    162 sg:journal.1115214 schema:issn 1087-0156
    163 1546-1696
    164 schema:name Nature Biotechnology
    165 schema:publisher Springer Nature
    166 rdf:type schema:Periodical
    167 sg:person.01112215062.32 schema:affiliation grid-institutes:grid.205975.c
    168 schema:familyName Lowe
    169 schema:givenName Craig B
    170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112215062.32
    171 rdf:type schema:Person
    172 sg:person.01127430011.25 schema:affiliation grid-institutes:grid.168010.e
    173 schema:familyName McLean
    174 schema:givenName Cory Y
    175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127430011.25
    176 rdf:type schema:Person
    177 sg:person.012106407613.52 schema:affiliation grid-institutes:grid.168010.e
    178 schema:familyName Wenger
    179 schema:givenName Aaron M
    180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012106407613.52
    181 rdf:type schema:Person
    182 sg:person.01304565413.15 schema:affiliation grid-institutes:grid.168010.e
    183 schema:familyName Schaar
    184 schema:givenName Bruce T
    185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304565413.15
    186 rdf:type schema:Person
    187 sg:person.0624077563.24 schema:affiliation grid-institutes:grid.168010.e
    188 schema:familyName Hiller
    189 schema:givenName Michael
    190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624077563.24
    191 rdf:type schema:Person
    192 sg:person.0677005046.22 schema:affiliation grid-institutes:grid.168010.e
    193 schema:familyName Bejerano
    194 schema:givenName Gill
    195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677005046.22
    196 rdf:type schema:Person
    197 sg:person.0776571131.70 schema:affiliation grid-institutes:grid.168010.e
    198 schema:familyName Clarke
    199 schema:givenName Shoa L
    200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776571131.70
    201 rdf:type schema:Person
    202 sg:pub.10.1038/35053516 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009729377
    203 https://doi.org/10.1038/35053516
    204 rdf:type schema:CreativeWork
    205 sg:pub.10.1038/35076601 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040585763
    206 https://doi.org/10.1038/35076601
    207 rdf:type schema:CreativeWork
    208 sg:pub.10.1038/75556 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044135237
    209 https://doi.org/10.1038/75556
    210 rdf:type schema:CreativeWork
    211 sg:pub.10.1038/nature04696 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027944303
    212 https://doi.org/10.1038/nature04696
    213 rdf:type schema:CreativeWork
    214 sg:pub.10.1038/nature05874 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005913886
    215 https://doi.org/10.1038/nature05874
    216 rdf:type schema:CreativeWork
    217 sg:pub.10.1038/nature07730 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021031479
    218 https://doi.org/10.1038/nature07730
    219 rdf:type schema:CreativeWork
    220 sg:pub.10.1038/nbt.1505 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051483764
    221 https://doi.org/10.1038/nbt.1505
    222 rdf:type schema:CreativeWork
    223 sg:pub.10.1038/nbt.1508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028515757
    224 https://doi.org/10.1038/nbt.1508
    225 rdf:type schema:CreativeWork
    226 sg:pub.10.1038/nbt.1518 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052955805
    227 https://doi.org/10.1038/nbt.1518
    228 rdf:type schema:CreativeWork
    229 sg:pub.10.1038/ng.113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002249517
    230 https://doi.org/10.1038/ng.113
    231 rdf:type schema:CreativeWork
    232 sg:pub.10.1038/ng.496 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037625384
    233 https://doi.org/10.1038/ng.496
    234 rdf:type schema:CreativeWork
    235 sg:pub.10.1038/nmeth.1246 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037362623
    236 https://doi.org/10.1038/nmeth.1246
    237 rdf:type schema:CreativeWork
    238 sg:pub.10.1038/nmeth0807-613 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051261645
    239 https://doi.org/10.1038/nmeth0807-613
    240 rdf:type schema:CreativeWork
    241 sg:pub.10.1038/nrg1001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018812708
    242 https://doi.org/10.1038/nrg1001
    243 rdf:type schema:CreativeWork
    244 sg:pub.10.1038/nrg1749 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017349746
    245 https://doi.org/10.1038/nrg1749
    246 rdf:type schema:CreativeWork
    247 sg:pub.10.1038/nrg2641 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006115199
    248 https://doi.org/10.1038/nrg2641
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1038/sj.onc.1209774 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044728705
    251 https://doi.org/10.1038/sj.onc.1209774
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1186/1471-2105-7-497 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018353192
    254 https://doi.org/10.1186/1471-2105-7-497
    255 rdf:type schema:CreativeWork
    256 grid-institutes:grid.168010.e schema:alternateName Department of Computer Science, Stanford University, Stanford, California, USA
    257 Department of Developmental Biology, Stanford University, Stanford, California, USA
    258 Department of Genetics, Stanford University, Stanford, California, USA
    259 schema:name Department of Computer Science, Stanford University, Stanford, California, USA
    260 Department of Developmental Biology, Stanford University, Stanford, California, USA
    261 Department of Genetics, Stanford University, Stanford, California, USA
    262 rdf:type schema:Organization
    263 grid-institutes:grid.205975.c schema:alternateName Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, USA
    264 schema:name Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, USA
    265 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...