Ontology type: schema:ScholarlyArticle Open Access: True
2010-05-02
AUTHORSCole Trapnell, Brian A Williams, Geo Pertea, Ali Mortazavi, Gordon Kwan, Marijke J van Baren, Steven L Salzberg, Barbara J Wold, Lior Pachter
ABSTRACTRNA-Seq enables rapid sequencing of total cellular RNA and should allow the reconstruction of spliced transcripts in a cell population. Trapnell et al. achieve this and transcript quantification using only paired-end RNA-Seq data and an unannotated genome sequence, and apply the approach to characterize isoform switching over a developmental time course. More... »
PAGES511-515
http://scigraph.springernature.com/pub.10.1038/nbt.1621
DOIhttp://dx.doi.org/10.1038/nbt.1621
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/20436464
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