S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-02

AUTHORS

Hiroshi Masumoto, Sachiko Muramatsu, Yoichiro Kamimura, Hiroyuki Araki

ABSTRACT

Cyclin-dependent protein kinases (Cdks) in eukaryotic cells work as a key enzyme at various points in the cell cycle. At the onset of S phase, active S-phase Cdks (S-Cdks) are essential for chromosomal DNA replication. Although several replication proteins are phosphorylated in a Cdk-dependent manner, the biological effects of phosphorylation of these proteins on the activation of DNA replication have not been elucidated. Here we show that Sld2 (ref. 4) (also known as Drc1; ref. 5), one of the replication proteins of budding yeast (Saccharomyces cerevisiae), is phosphorylated in S phase in an S-Cdk-dependent manner, and mutant Sld2 lacking all the preferred Cdk phosphorylation sites (All-A) is defective in chromosomal DNA replication. Moreover, the complex that contains, at least, Sld2 and Dpb11 (ref. 6) (the Sld2-Dpb11 complex) is formed predominantly in S phase; the All-A protein is defective in this complex formation. Because this complex is suggested to be essential for chromosomal DNA replication, it seems likely that S-Cdk positively regulates formation of the Sld2-Dpb11 complex and, consequently, chromosomal DNA replication. More... »

PAGES

651

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature713

DOI

http://dx.doi.org/10.1038/nature713

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049620350

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11807498


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carrier Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Cycle Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Fungal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cyclin-Dependent Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Replication", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Fungal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fungal Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phosphorylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Point Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomyces cerevisiae Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomycetales", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Schizosaccharomyces pombe Proteins", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Japan Science and Technology Agency", 
          "id": "https://www.grid.ac/institutes/grid.419082.6", 
          "name": [
            "*Division of Microbial Genetics, National Institute of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan", 
            "\u2021PRESTO, JST, Kawaguchi, Saitama 332-0012, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Masumoto", 
        "givenName": "Hiroshi", 
        "id": "sg:person.01073202740.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073202740.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Genetics", 
          "id": "https://www.grid.ac/institutes/grid.288127.6", 
          "name": [
            "*Division of Microbial Genetics, National Institute of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Muramatsu", 
        "givenName": "Sachiko", 
        "id": "sg:person.01205434476.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01205434476.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Graduate University For Advanced Studies", 
          "id": "https://www.grid.ac/institutes/grid.275033.0", 
          "name": [
            "*Division of Microbial Genetics, National Institute of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan", 
            "\u2020Department of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kamimura", 
        "givenName": "Yoichiro", 
        "id": "sg:person.01321663076.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321663076.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Graduate University For Advanced Studies", 
          "id": "https://www.grid.ac/institutes/grid.275033.0", 
          "name": [
            "*Division of Microbial Genetics, National Institute of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan", 
            "\u2020Department of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Araki", 
        "givenName": "Hiroyuki", 
        "id": "sg:person.015157102075.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015157102075.61"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0076-6879(91)00127-i", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002372344"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1091/mbc.10.10.3263", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002396759"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0960-9822(00)00337-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002462108"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0960-9822(00)00355-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003508210"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0962-8924(99)01586-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005052165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/17.17.5182", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005875409"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(92)90454-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006240990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(92)90454-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006240990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/357128a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008093514", 
          "https://doi.org/10.1038/357128a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.92.25.11791", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009601194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/20.8.2097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010219249"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/jcs.1995.supplement_19.9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013712387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(01)80009-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018526826"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81684-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026678681"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.4.1.9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032293561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.20.8.2809-2817.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035125901"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35082600", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036007845", 
          "https://doi.org/10.1038/35082600"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35082600", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036007845", 
          "https://doi.org/10.1038/35082600"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/15649", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039277346", 
          "https://doi.org/10.1038/15649"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/15649", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039277346", 
          "https://doi.org/10.1038/15649"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0168-9525(96)10041-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039419962"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.275.13.9734", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040949819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.20.9.3086-3096.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043938891"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.18.10.6102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045383676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.biochem.69.1.829", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045424909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.96.7.3824", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047014126"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.15.2.883", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048390276"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.96.16.9130", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049376340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.4.6.968", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052278170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(94)90193-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052609172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.279.5354.1216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062559682"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.280.5363.593", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062560868"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079183246", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2002-02", 
    "datePublishedReg": "2002-02-01", 
    "description": "Cyclin-dependent protein kinases (Cdks) in eukaryotic cells work as a key enzyme at various points in the cell cycle. At the onset of S phase, active S-phase Cdks (S-Cdks) are essential for chromosomal DNA replication. Although several replication proteins are phosphorylated in a Cdk-dependent manner, the biological effects of phosphorylation of these proteins on the activation of DNA replication have not been elucidated. Here we show that Sld2 (ref. 4) (also known as Drc1; ref. 5), one of the replication proteins of budding yeast (Saccharomyces cerevisiae), is phosphorylated in S phase in an S-Cdk-dependent manner, and mutant Sld2 lacking all the preferred Cdk phosphorylation sites (All-A) is defective in chromosomal DNA replication. Moreover, the complex that contains, at least, Sld2 and Dpb11 (ref. 6) (the Sld2-Dpb11 complex) is formed predominantly in S phase; the All-A protein is defective in this complex formation. Because this complex is suggested to be essential for chromosomal DNA replication, it seems likely that S-Cdk positively regulates formation of the Sld2-Dpb11 complex and, consequently, chromosomal DNA replication.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nature713", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6872", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "415"
      }
    ], 
    "name": "S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast", 
    "pagination": "651", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ec609bdc8f5a98d0964860c534496cca3292a70c832343bec0ca8c0d31087c00"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "11807498"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature713"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1049620350"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature713", 
      "https://app.dimensions.ai/details/publication/pub.1049620350"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:25", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87106_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/nature713"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature713'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature713'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature713'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature713'


 

This table displays all metadata directly associated to this object as RDF triples.

238 TRIPLES      21 PREDICATES      71 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature713 schema:about N1cf32787cbb84975910fa9662c08b770
2 N234101b71f6c41c0bcb6b620742b30bb
3 N23fa625309d1424684ee0a6017e730c2
4 N39101ba307934b4ca8f436cc9f36e415
5 N59758918e483496bbdae8aab44c44dd6
6 N610ad427941e447b89d5fd734f3b7cbe
7 N7cc7e52e568b4e0c9304cea7e46398b2
8 N8cf24e46469144adab747f7781bd805a
9 Nada10eb62bb34c1eaba7594989009edd
10 Nc17904e7533a4a94a3de9178b100e73c
11 Ndbfd7a9c5c80401288ffdfdba5a1e5f1
12 Nfc5097a5277f46859f12ca28cb946425
13 anzsrc-for:06
14 anzsrc-for:0601
15 schema:author N6cef41054847445e91fc3bb98f72e881
16 schema:citation sg:pub.10.1038/15649
17 sg:pub.10.1038/35082600
18 sg:pub.10.1038/357128a0
19 https://app.dimensions.ai/details/publication/pub.1079183246
20 https://doi.org/10.1016/0076-6879(91)00127-i
21 https://doi.org/10.1016/0092-8674(94)90193-7
22 https://doi.org/10.1016/0168-9525(96)10041-x
23 https://doi.org/10.1016/0378-1119(92)90454-w
24 https://doi.org/10.1016/s0092-8674(00)81684-0
25 https://doi.org/10.1016/s0092-8674(01)80009-x
26 https://doi.org/10.1016/s0960-9822(00)00337-7
27 https://doi.org/10.1016/s0960-9822(00)00355-9
28 https://doi.org/10.1016/s0962-8924(99)01586-x
29 https://doi.org/10.1073/pnas.92.25.11791
30 https://doi.org/10.1073/pnas.96.16.9130
31 https://doi.org/10.1073/pnas.96.7.3824
32 https://doi.org/10.1074/jbc.275.13.9734
33 https://doi.org/10.1091/mbc.10.10.3263
34 https://doi.org/10.1093/emboj/17.17.5182
35 https://doi.org/10.1093/emboj/20.8.2097
36 https://doi.org/10.1101/gad.4.1.9
37 https://doi.org/10.1101/gad.4.6.968
38 https://doi.org/10.1126/science.279.5354.1216
39 https://doi.org/10.1126/science.280.5363.593
40 https://doi.org/10.1128/mcb.15.2.883
41 https://doi.org/10.1128/mcb.18.10.6102
42 https://doi.org/10.1128/mcb.20.8.2809-2817.2000
43 https://doi.org/10.1128/mcb.20.9.3086-3096.2000
44 https://doi.org/10.1146/annurev.biochem.69.1.829
45 https://doi.org/10.1242/jcs.1995.supplement_19.9
46 schema:datePublished 2002-02
47 schema:datePublishedReg 2002-02-01
48 schema:description Cyclin-dependent protein kinases (Cdks) in eukaryotic cells work as a key enzyme at various points in the cell cycle. At the onset of S phase, active S-phase Cdks (S-Cdks) are essential for chromosomal DNA replication. Although several replication proteins are phosphorylated in a Cdk-dependent manner, the biological effects of phosphorylation of these proteins on the activation of DNA replication have not been elucidated. Here we show that Sld2 (ref. 4) (also known as Drc1; ref. 5), one of the replication proteins of budding yeast (Saccharomyces cerevisiae), is phosphorylated in S phase in an S-Cdk-dependent manner, and mutant Sld2 lacking all the preferred Cdk phosphorylation sites (All-A) is defective in chromosomal DNA replication. Moreover, the complex that contains, at least, Sld2 and Dpb11 (ref. 6) (the Sld2-Dpb11 complex) is formed predominantly in S phase; the All-A protein is defective in this complex formation. Because this complex is suggested to be essential for chromosomal DNA replication, it seems likely that S-Cdk positively regulates formation of the Sld2-Dpb11 complex and, consequently, chromosomal DNA replication.
49 schema:genre research_article
50 schema:inLanguage en
51 schema:isAccessibleForFree false
52 schema:isPartOf N7d9bf82d38014c0f96e077a4d8aa3b00
53 N9001f231509d47449565cfc12254d8f5
54 sg:journal.1018957
55 schema:name S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast
56 schema:pagination 651
57 schema:productId N0911b7b59d8d4a2280558592b757588f
58 N09fd580bdc2f4d1a8d8bd43702647197
59 N66973835b2a44d26b46fadef8f1b1871
60 Na2899b5a284542e6af2e882e1f4a6e51
61 Nbd12a060b4ea493e8294bd066f3c6437
62 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049620350
63 https://doi.org/10.1038/nature713
64 schema:sdDatePublished 2019-04-11T12:25
65 schema:sdLicense https://scigraph.springernature.com/explorer/license/
66 schema:sdPublisher Ncb01bdba482447a5a310b113283aa0fa
67 schema:url https://www.nature.com/articles/nature713
68 sgo:license sg:explorer/license/
69 sgo:sdDataset articles
70 rdf:type schema:ScholarlyArticle
71 N0911b7b59d8d4a2280558592b757588f schema:name nlm_unique_id
72 schema:value 0410462
73 rdf:type schema:PropertyValue
74 N09fd580bdc2f4d1a8d8bd43702647197 schema:name dimensions_id
75 schema:value pub.1049620350
76 rdf:type schema:PropertyValue
77 N1cf32787cbb84975910fa9662c08b770 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Schizosaccharomyces pombe Proteins
79 rdf:type schema:DefinedTerm
80 N234101b71f6c41c0bcb6b620742b30bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Fungal Proteins
82 rdf:type schema:DefinedTerm
83 N23fa625309d1424684ee0a6017e730c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name DNA, Fungal
85 rdf:type schema:DefinedTerm
86 N39101ba307934b4ca8f436cc9f36e415 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Point Mutation
88 rdf:type schema:DefinedTerm
89 N59758918e483496bbdae8aab44c44dd6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Phosphorylation
91 rdf:type schema:DefinedTerm
92 N610ad427941e447b89d5fd734f3b7cbe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Carrier Proteins
94 rdf:type schema:DefinedTerm
95 N66973835b2a44d26b46fadef8f1b1871 schema:name pubmed_id
96 schema:value 11807498
97 rdf:type schema:PropertyValue
98 N6cef41054847445e91fc3bb98f72e881 rdf:first sg:person.01073202740.31
99 rdf:rest Nbc283828986d466aa5995e8327438595
100 N706e5cd7a1224d9c9a58d86f7e9d3f50 rdf:first sg:person.01321663076.98
101 rdf:rest Nbdabc280306d455bbf512b9cb301fdcf
102 N7cc7e52e568b4e0c9304cea7e46398b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Cell Cycle Proteins
104 rdf:type schema:DefinedTerm
105 N7d9bf82d38014c0f96e077a4d8aa3b00 schema:volumeNumber 415
106 rdf:type schema:PublicationVolume
107 N8cf24e46469144adab747f7781bd805a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Cyclin-Dependent Kinases
109 rdf:type schema:DefinedTerm
110 N9001f231509d47449565cfc12254d8f5 schema:issueNumber 6872
111 rdf:type schema:PublicationIssue
112 Na2899b5a284542e6af2e882e1f4a6e51 schema:name doi
113 schema:value 10.1038/nature713
114 rdf:type schema:PropertyValue
115 Nada10eb62bb34c1eaba7594989009edd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name DNA Replication
117 rdf:type schema:DefinedTerm
118 Nbc283828986d466aa5995e8327438595 rdf:first sg:person.01205434476.75
119 rdf:rest N706e5cd7a1224d9c9a58d86f7e9d3f50
120 Nbd12a060b4ea493e8294bd066f3c6437 schema:name readcube_id
121 schema:value ec609bdc8f5a98d0964860c534496cca3292a70c832343bec0ca8c0d31087c00
122 rdf:type schema:PropertyValue
123 Nbdabc280306d455bbf512b9cb301fdcf rdf:first sg:person.015157102075.61
124 rdf:rest rdf:nil
125 Nc17904e7533a4a94a3de9178b100e73c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Saccharomycetales
127 rdf:type schema:DefinedTerm
128 Ncb01bdba482447a5a310b113283aa0fa schema:name Springer Nature - SN SciGraph project
129 rdf:type schema:Organization
130 Ndbfd7a9c5c80401288ffdfdba5a1e5f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Saccharomyces cerevisiae Proteins
132 rdf:type schema:DefinedTerm
133 Nfc5097a5277f46859f12ca28cb946425 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Chromosomes, Fungal
135 rdf:type schema:DefinedTerm
136 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
137 schema:name Biological Sciences
138 rdf:type schema:DefinedTerm
139 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
140 schema:name Biochemistry and Cell Biology
141 rdf:type schema:DefinedTerm
142 sg:journal.1018957 schema:issn 0090-0028
143 1476-4687
144 schema:name Nature
145 rdf:type schema:Periodical
146 sg:person.01073202740.31 schema:affiliation https://www.grid.ac/institutes/grid.419082.6
147 schema:familyName Masumoto
148 schema:givenName Hiroshi
149 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073202740.31
150 rdf:type schema:Person
151 sg:person.01205434476.75 schema:affiliation https://www.grid.ac/institutes/grid.288127.6
152 schema:familyName Muramatsu
153 schema:givenName Sachiko
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01205434476.75
155 rdf:type schema:Person
156 sg:person.01321663076.98 schema:affiliation https://www.grid.ac/institutes/grid.275033.0
157 schema:familyName Kamimura
158 schema:givenName Yoichiro
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321663076.98
160 rdf:type schema:Person
161 sg:person.015157102075.61 schema:affiliation https://www.grid.ac/institutes/grid.275033.0
162 schema:familyName Araki
163 schema:givenName Hiroyuki
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015157102075.61
165 rdf:type schema:Person
166 sg:pub.10.1038/15649 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039277346
167 https://doi.org/10.1038/15649
168 rdf:type schema:CreativeWork
169 sg:pub.10.1038/35082600 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036007845
170 https://doi.org/10.1038/35082600
171 rdf:type schema:CreativeWork
172 sg:pub.10.1038/357128a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008093514
173 https://doi.org/10.1038/357128a0
174 rdf:type schema:CreativeWork
175 https://app.dimensions.ai/details/publication/pub.1079183246 schema:CreativeWork
176 https://doi.org/10.1016/0076-6879(91)00127-i schema:sameAs https://app.dimensions.ai/details/publication/pub.1002372344
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1016/0092-8674(94)90193-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052609172
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1016/0168-9525(96)10041-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039419962
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1016/0378-1119(92)90454-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1006240990
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1016/s0092-8674(00)81684-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026678681
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/s0092-8674(01)80009-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018526826
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/s0960-9822(00)00337-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002462108
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/s0960-9822(00)00355-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003508210
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/s0962-8924(99)01586-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005052165
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1073/pnas.92.25.11791 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009601194
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1073/pnas.96.16.9130 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049376340
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1073/pnas.96.7.3824 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047014126
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1074/jbc.275.13.9734 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040949819
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1091/mbc.10.10.3263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002396759
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1093/emboj/17.17.5182 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005875409
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1093/emboj/20.8.2097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010219249
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1101/gad.4.1.9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032293561
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1101/gad.4.6.968 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052278170
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1126/science.279.5354.1216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062559682
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1126/science.280.5363.593 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062560868
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1128/mcb.15.2.883 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048390276
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1128/mcb.18.10.6102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045383676
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1128/mcb.20.8.2809-2817.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035125901
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1128/mcb.20.9.3086-3096.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043938891
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1146/annurev.biochem.69.1.829 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045424909
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1242/jcs.1995.supplement_19.9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013712387
227 rdf:type schema:CreativeWork
228 https://www.grid.ac/institutes/grid.275033.0 schema:alternateName Graduate University For Advanced Studies
229 schema:name *Division of Microbial Genetics, National Institute of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan
230 †Department of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan
231 rdf:type schema:Organization
232 https://www.grid.ac/institutes/grid.288127.6 schema:alternateName National Institute of Genetics
233 schema:name *Division of Microbial Genetics, National Institute of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan
234 rdf:type schema:Organization
235 https://www.grid.ac/institutes/grid.419082.6 schema:alternateName Japan Science and Technology Agency
236 schema:name *Division of Microbial Genetics, National Institute of Genetics, The Graduate University for Advanced Studies, Yata 1111, Mishima, Shizuoka 411-8540, Japan
237 ‡PRESTO, JST, Kawaguchi, Saitama 332-0012, Japan
238 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...