DNA methylation-based classification of central nervous system tumours View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-03

AUTHORS

David Capper, David T. W. Jones, Martin Sill, Volker Hovestadt, Daniel Schrimpf, Dominik Sturm, Christian Koelsche, Felix Sahm, Lukas Chavez, David E. Reuss, Annekathrin Kratz, Annika K. Wefers, Kristin Huang, Kristian W. Pajtler, Leonille Schweizer, Damian Stichel, Adriana Olar, Nils W. Engel, Kerstin Lindenberg, Patrick N. Harter, Anne K. Braczynski, Karl H. Plate, Hildegard Dohmen, Boyan K. Garvalov, Roland Coras, Annett Hölsken, Ekkehard Hewer, Melanie Bewerunge-Hudler, Matthias Schick, Roger Fischer, Rudi Beschorner, Jens Schittenhelm, Ori Staszewski, Khalida Wani, Pascale Varlet, Melanie Pages, Petra Temming, Dietmar Lohmann, Florian Selt, Hendrik Witt, Till Milde, Olaf Witt, Eleonora Aronica, Felice Giangaspero, Elisabeth Rushing, Wolfram Scheurlen, Christoph Geisenberger, Fausto J. Rodriguez, Albert Becker, Matthias Preusser, Christine Haberler, Rolf Bjerkvig, Jane Cryan, Michael Farrell, Martina Deckert, Jürgen Hench, Stephan Frank, Jonathan Serrano, Kasthuri Kannan, Aristotelis Tsirigos, Wolfgang Brück, Silvia Hofer, Stefanie Brehmer, Marcel Seiz-Rosenhagen, Daniel Hänggi, Volkmar Hans, Stephanie Rozsnoki, Jordan R. Hansford, Patricia Kohlhof, Bjarne W. Kristensen, Matt Lechner, Beatriz Lopes, Christian Mawrin, Ralf Ketter, Andreas Kulozik, Ziad Khatib, Frank Heppner, Arend Koch, Anne Jouvet, Catherine Keohane, Helmut Mühleisen, Wolf Mueller, Ute Pohl, Marco Prinz, Axel Benner, Marc Zapatka, Nicholas G. Gottardo, Pablo Hernáiz Driever, Christof M. Kramm, Hermann L. Müller, Stefan Rutkowski, Katja von Hoff, Michael C. Frühwald, Astrid Gnekow, Gudrun Fleischhack, Stephan Tippelt, Gabriele Calaminus, Camelia-Maria Monoranu, Arie Perry, Chris Jones, Thomas S. Jacques, Bernhard Radlwimmer, Marco Gessi, Torsten Pietsch, Johannes Schramm, Gabriele Schackert, Manfred Westphal, Guido Reifenberger, Pieter Wesseling, Michael Weller, Vincent Peter Collins, Ingmar Blümcke, Martin Bendszus, Jürgen Debus, Annie Huang, Nada Jabado, Paul A. Northcott, Werner Paulus, Amar Gajjar, Giles W. Robinson, Michael D. Taylor, Zane Jaunmuktane, Marina Ryzhova, Michael Platten, Andreas Unterberg, Wolfgang Wick, Matthias A. Karajannis, Michel Mittelbronn, Till Acker, Christian Hartmann, Kenneth Aldape, Ulrich Schüller, Rolf Buslei, Peter Lichter, Marcel Kool, Christel Herold-Mende, David W. Ellison, Martin Hasselblatt, Matija Snuderl, Sebastian Brandner, Andrey Korshunov, Andreas von Deimling, Stefan M. Pfister

ABSTRACT

Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-with substantial inter-observer variability in the histopathological diagnosis of many tumour types. Here we present a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and demonstrate its application in a routine diagnostic setting. We show that the availability of this method may have a substantial impact on diagnostic precision compared to standard methods, resulting in a change of diagnosis in up to 12% of prospective cases. For broader accessibility, we have designed a free online classifier tool, the use of which does not require any additional onsite data processing. Our results provide a blueprint for the generation of machine-learning-based tumour classifiers across other cancer entities, with the potential to fundamentally transform tumour pathology. More... »

PAGES

469

References to SciGraph publications

  • 2011-12. Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts in JOURNAL OF NEGATIVE RESULTS IN BIOMEDICINE
  • 2013-08. Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma in ACTA NEUROPATHOLOGICA
  • 2016-12. Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles in ACTA NEUROPATHOLOGICA COMMUNICATIONS
  • 2013-06. Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays in ACTA NEUROPATHOLOGICA
  • 2015-05. Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups in ACTA NEUROPATHOLOGICA
  • 2001-11. A Simple Generalisation of the Area Under the ROC Curve for Multiple Class Classification Problems in MACHINE LEARNING
  • 2015-02. Orchestrating high-throughput genomic analysis with Bioconductor in NATURE METHODS
  • 2014-10. Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma in ACTA NEUROPATHOLOGICA
  • 2014-06. Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing in NATURE
  • 2014-02. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy in NATURE
  • 2013-08. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma in NATURE GENETICS
  • 2014-07. Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort in ACTA NEUROPATHOLOGICA
  • 2012-08. Dissecting the genomic complexity underlying medulloblastoma in NATURE
  • 2012-05. Absolute quantification of somatic DNA alterations in human cancer in NATURE BIOTECHNOLOGY
  • 2016-06. Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets in ACTA NEUROPATHOLOGICA
  • 2014-08. Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity in ACTA NEUROPATHOLOGICA
  • 2016-01. Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity in ACTA NEUROPATHOLOGICA
  • 2001-10. Random Forests in MACHINE LEARNING
  • 2015-09. Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities in ACTA NEUROPATHOLOGICA
  • 2010-09. Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician’s perspective in ACTA NEUROPATHOLOGICA
  • 2012-01. Reinventing clinical trials in NATURE BIOTECHNOLOGY
  • Journal

    TITLE

    Nature

    ISSUE

    7697

    VOLUME

    555

    Author Affiliations

  • German Cancer Research Center
  • University Hospital Heidelberg
  • Hollings Cancer Center
  • Ludwig Maximilian University of Munich
  • University of Giessen
  • University of Bern
  • Universitätsklinikum Tübingen
  • The University of Texas MD Anderson Cancer Center
  • Centre Hospitalier Sainte-Anne
  • Essen University Hospital
  • University of Duisburg-Essen
  • Stichting Epilepsie Instellingen Nederland
  • Istituto Neurologico Mediterraneo
  • University Hospital of Zurich
  • Cnopf´sche Kinderklinik
  • Hubrecht Institute
  • Johns Hopkins University
  • University of Bonn
  • Medical University of Vienna
  • Luxembourg Institute of Health
  • Beaumont Hospital
  • University Hospital Cologne
  • University Hospital of Basel
  • New York University Langone Medical Center
  • Universitätsmedizin Göttingen
  • Luzerner Kantonsspital
  • University Medical Centre Mannheim
  • University Hospital Münster
  • University of Melbourne
  • University College London
  • University of Virginia
  • Otto-von-Guericke University Magdeburg
  • Universitätsklinikum des Saarlandes
  • Miami Children's Hospital
  • Berlin Institute of Health
  • Hôpital Pierre Wertheimer
  • Cork University Hospital
  • Leipzig University
  • Queen's Hospital
  • University of Freiburg
  • University of Western Australia
  • Charité
  • Carl von Ossietzky University of Oldenburg
  • University Medical Center Hamburg-Eppendorf
  • University Hospital Bonn
  • University of Würzburg
  • University of California, San Francisco
  • Institute of Cancer Research
  • Great Ormond Street Hospital for Children NHS Foundation Trust
  • VU University Medical Center
  • University of Zurich
  • University of Cambridge
  • University of Toronto
  • McGill University
  • St. Jude Children's Research Hospital
  • Burdenko Neurosurgery Institute
  • Memorial Sloan Kettering Cancer Center
  • Laboratoire National de Santé
  • Hannover Medical School
  • Sozialstiftung Bamberg
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature26000

    DOI

    http://dx.doi.org/10.1038/nature26000

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1101533700

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29539639


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Oncology and Carcinogenesis", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adolescent", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged, 80 and over", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Central Nervous System Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Child", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Child, Preschool", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cohort Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "DNA Methylation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Infant", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Reproducibility of Results", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Unsupervised Machine Learning", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Young Adult", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany", 
                "Charit\u00e9 \u2014 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany", 
                "German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Capper", 
            "givenName": "David", 
            "id": "sg:person.01043273753.26", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043273753.26"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jones", 
            "givenName": "David T. W.", 
            "id": "sg:person.011536141544.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011536141544.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany", 
                "Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sill", 
            "givenName": "Martin", 
            "id": "sg:person.01104073627.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104073627.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hovestadt", 
            "givenName": "Volker", 
            "id": "sg:person.0610463215.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610463215.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schrimpf", 
            "givenName": "Daniel", 
            "id": "sg:person.01234464637.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234464637.55"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany", 
                "Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sturm", 
            "givenName": "Dominik", 
            "id": "sg:person.01124352515.36", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124352515.36"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Koelsche", 
            "givenName": "Christian", 
            "id": "sg:person.01153246175.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153246175.48"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sahm", 
            "givenName": "Felix", 
            "id": "sg:person.0775160553.49", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775160553.49"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chavez", 
            "givenName": "Lukas", 
            "id": "sg:person.01250404162.21", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250404162.21"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Reuss", 
            "givenName": "David E.", 
            "id": "sg:person.01074367672.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074367672.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kratz", 
            "givenName": "Annekathrin", 
            "id": "sg:person.01342767063.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342767063.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wefers", 
            "givenName": "Annika K.", 
            "id": "sg:person.0747034720.79", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747034720.79"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Huang", 
            "givenName": "Kristin", 
            "id": "sg:person.015355630434.80", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015355630434.80"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany", 
                "Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pajtler", 
            "givenName": "Kristian W.", 
            "id": "sg:person.0647670107.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647670107.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Charit\u00e9 \u2014 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schweizer", 
            "givenName": "Leonille", 
            "id": "sg:person.01053310042.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053310042.43"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Stichel", 
            "givenName": "Damian", 
            "id": "sg:person.01243232701.95", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243232701.95"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hollings Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.467988.c", 
              "name": [
                "Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina 29425, USA", 
                "Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA", 
                "Hollings Cancer Center, Charleston, South Carolina 29425, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Olar", 
            "givenName": "Adriana", 
            "id": "sg:person.0637473041.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637473041.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Ludwig Maximilian University of Munich", 
              "id": "https://www.grid.ac/institutes/grid.5252.0", 
              "name": [
                "Department of Oncology and Hematology with Sections Bone Marrow Transplant and Pneumology, Hubertus Wald Tumorzentrum/University Cancer Center Hamburg, University Medical Center Hamburg, Hamburg, Germany", 
                "Center for Neuropathology and Prion Research, Ludwig-Maximilians-University, Munich, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Engel", 
            "givenName": "Nils W.", 
            "id": "sg:person.0743051543.84", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743051543.84"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lindenberg", 
            "givenName": "Kerstin", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Institute of Neurology (Edinger Institute), Goethe-University Frankfurt am Main, Frankfurt am Main, Germany", 
                "German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, German Cancer Research Center (DKFZ) Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Harter", 
            "givenName": "Patrick N.", 
            "id": "sg:person.01260265434.38", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260265434.38"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Institute of Neurology (Edinger Institute), Goethe-University Frankfurt am Main, Frankfurt am Main, Germany", 
                "German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, German Cancer Research Center (DKFZ) Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Braczynski", 
            "givenName": "Anne K.", 
            "id": "sg:person.0736755752.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736755752.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Institute of Neurology (Edinger Institute), Goethe-University Frankfurt am Main, Frankfurt am Main, Germany", 
                "German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, German Cancer Research Center (DKFZ) Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Plate", 
            "givenName": "Karl H.", 
            "id": "sg:person.0657742371.33", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657742371.33"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Giessen", 
              "id": "https://www.grid.ac/institutes/grid.8664.c", 
              "name": [
                "Institute of Neuropathology, University of Giessen, Giessen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dohmen", 
            "givenName": "Hildegard", 
            "id": "sg:person.015472057034.65", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015472057034.65"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Giessen", 
              "id": "https://www.grid.ac/institutes/grid.8664.c", 
              "name": [
                "Institute of Neuropathology, University of Giessen, Giessen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Garvalov", 
            "givenName": "Boyan K.", 
            "id": "sg:person.01235252033.21", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235252033.21"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Neuropathological Institute, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Coras", 
            "givenName": "Roland", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Neuropathological Institute, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "H\u00f6lsken", 
            "givenName": "Annett", 
            "id": "sg:person.0773150274.84", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773150274.84"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bern", 
              "id": "https://www.grid.ac/institutes/grid.5734.5", 
              "name": [
                "Institute of Pathology, University of Bern, Bern, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hewer", 
            "givenName": "Ekkehard", 
            "id": "sg:person.0742653406.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742653406.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Genomics and Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bewerunge-Hudler", 
            "givenName": "Melanie", 
            "id": "sg:person.01130262430.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130262430.09"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Genomics and Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schick", 
            "givenName": "Matthias", 
            "id": "sg:person.01175561336.61", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175561336.61"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Genomics and Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fischer", 
            "givenName": "Roger", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Universit\u00e4tsklinikum T\u00fcbingen", 
              "id": "https://www.grid.ac/institutes/grid.411544.1", 
              "name": [
                "Institute of Pathology and Neuropathology, Department of Neuropathology, University Hospital T\u00fcbingen, T\u00fcbingen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Beschorner", 
            "givenName": "Rudi", 
            "id": "sg:person.0653406766.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653406766.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Universit\u00e4tsklinikum T\u00fcbingen", 
              "id": "https://www.grid.ac/institutes/grid.411544.1", 
              "name": [
                "Institute of Pathology and Neuropathology, Department of Neuropathology, University Hospital T\u00fcbingen, T\u00fcbingen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schittenhelm", 
            "givenName": "Jens", 
            "id": "sg:person.0607426433.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607426433.30"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Institute of Neuropathology, Medical Center\u2013University of Freiburg, Faculty of Medicine, University of Freiburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Staszewski", 
            "givenName": "Ori", 
            "id": "sg:person.01222402317.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222402317.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The University of Texas MD Anderson Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.240145.6", 
              "name": [
                "Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wani", 
            "givenName": "Khalida", 
            "id": "sg:person.010222631377.97", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010222631377.97"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Centre Hospitalier Sainte-Anne", 
              "id": "https://www.grid.ac/institutes/grid.414435.3", 
              "name": [
                "Department of Neuropathology, Centre Hospitalier Sainte Anne, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Varlet", 
            "givenName": "Pascale", 
            "id": "sg:person.01030642337.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030642337.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Centre Hospitalier Sainte-Anne", 
              "id": "https://www.grid.ac/institutes/grid.414435.3", 
              "name": [
                "Department of Neuropathology, Centre Hospitalier Sainte Anne, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pages", 
            "givenName": "Melanie", 
            "id": "sg:person.0675572337.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675572337.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Essen University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.410718.b", 
              "name": [
                "Pediatrics III, Pediatric Oncology and Hematology, University Hospital Essen, Essen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Temming", 
            "givenName": "Petra", 
            "id": "sg:person.01064137712.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064137712.31"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Duisburg-Essen", 
              "id": "https://www.grid.ac/institutes/grid.5718.b", 
              "name": [
                "Eye Cancer Research Group, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lohmann", 
            "givenName": "Dietmar", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany", 
                "CCU Pediatric Oncology (G340), German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Selt", 
            "givenName": "Florian", 
            "id": "sg:person.013567220602.01", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013567220602.01"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany", 
                "Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Witt", 
            "givenName": "Hendrik", 
            "id": "sg:person.0757363774.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757363774.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany", 
                "CCU Pediatric Oncology (G340), German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Milde", 
            "givenName": "Till", 
            "id": "sg:person.01306714315.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306714315.48"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany", 
                "CCU Pediatric Oncology (G340), German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Witt", 
            "givenName": "Olaf", 
            "id": "sg:person.01367420407.26", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367420407.26"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Stichting Epilepsie Instellingen Nederland", 
              "id": "https://www.grid.ac/institutes/grid.419298.f", 
              "name": [
                "Department of (Neuro)Pathology, Academic Medisch Centrum (AMC), University of Amsterdam, Amsterdam, The Netherlands", 
                "Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands", 
                "Stichting Epilepsie Instellingen Nederland (SEIN), Amsterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Aronica", 
            "givenName": "Eleonora", 
            "id": "sg:person.01361245264.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361245264.52"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Istituto Neurologico Mediterraneo", 
              "id": "https://www.grid.ac/institutes/grid.419543.e", 
              "name": [
                "Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza University, Rome, Italy", 
                "IRCCS Neuromed, Pozzilli, Italy"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Giangaspero", 
            "givenName": "Felice", 
            "id": "sg:person.01051617612.15", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051617612.15"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital of Zurich", 
              "id": "https://www.grid.ac/institutes/grid.412004.3", 
              "name": [
                "Department of Neuropathology, University Hospital Zurich, Zurich, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rushing", 
            "givenName": "Elisabeth", 
            "id": "sg:person.0721513443.35", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721513443.35"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cnopf\u00b4sche Kinderklinik", 
              "id": "https://www.grid.ac/institutes/grid.490647.8", 
              "name": [
                "Cnopf\u2019sche Kinderklinik Nuremberg, Nuremberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Scheurlen", 
            "givenName": "Wolfram", 
            "id": "sg:person.0600137763.92", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600137763.92"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hubrecht Institute", 
              "id": "https://www.grid.ac/institutes/grid.419927.0", 
              "name": [
                "Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany", 
                "Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences), Uppsalalaan 8, 3584 CT Utrecht, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Geisenberger", 
            "givenName": "Christoph", 
            "id": "sg:person.01261675111.82", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261675111.82"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Division of Neuropathology of the Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rodriguez", 
            "givenName": "Fausto J.", 
            "id": "sg:person.01023212571.19", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023212571.19"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Department of Neuropathology, University of Bonn, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Becker", 
            "givenName": "Albert", 
            "id": "sg:person.01312431477.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312431477.50"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical University of Vienna", 
              "id": "https://www.grid.ac/institutes/grid.22937.3d", 
              "name": [
                "Department of Medicine I, Comprehensive Cancer Center Vienna, CNS Unit (CCC-CNS), Medical University of Vienna, Vienna, Austria"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Preusser", 
            "givenName": "Matthias", 
            "id": "sg:person.01247463220.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247463220.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical University of Vienna", 
              "id": "https://www.grid.ac/institutes/grid.22937.3d", 
              "name": [
                "Institute of Neurology, Medical University of Vienna, Vienna, Austria"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Haberler", 
            "givenName": "Christine", 
            "id": "sg:person.0633773522.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633773522.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Luxembourg Institute of Health", 
              "id": "https://www.grid.ac/institutes/grid.451012.3", 
              "name": [
                "Department of Biomedicine, University of Bergen, Bergen, Norway", 
                "NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bjerkvig", 
            "givenName": "Rolf", 
            "id": "sg:person.01125313653.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125313653.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Beaumont Hospital", 
              "id": "https://www.grid.ac/institutes/grid.414315.6", 
              "name": [
                "Department of Neuropathology, Beaumont Hospital, Dublin, Ireland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cryan", 
            "givenName": "Jane", 
            "id": "sg:person.01134175470.77", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134175470.77"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Beaumont Hospital", 
              "id": "https://www.grid.ac/institutes/grid.414315.6", 
              "name": [
                "Department of Neuropathology, Beaumont Hospital, Dublin, Ireland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Farrell", 
            "givenName": "Michael", 
            "id": "sg:person.015657111262.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015657111262.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Cologne", 
              "id": "https://www.grid.ac/institutes/grid.411097.a", 
              "name": [
                "Department of Neuropathology, University Hospital of Cologne, Cologne, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Deckert", 
            "givenName": "Martina", 
            "id": "sg:person.01242715675.01", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242715675.01"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital of Basel", 
              "id": "https://www.grid.ac/institutes/grid.410567.1", 
              "name": [
                "Department of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hench", 
            "givenName": "J\u00fcrgen", 
            "id": "sg:person.01274547566.64", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274547566.64"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital of Basel", 
              "id": "https://www.grid.ac/institutes/grid.410567.1", 
              "name": [
                "Department of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Frank", 
            "givenName": "Stephan", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "New York University Langone Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.240324.3", 
              "name": [
                "NYU Langone Medical Center, New York, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Serrano", 
            "givenName": "Jonathan", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "New York University Langone Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.240324.3", 
              "name": [
                "NYU Langone Medical Center, New York, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kannan", 
            "givenName": "Kasthuri", 
            "id": "sg:person.01050265446.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050265446.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "New York University Langone Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.240324.3", 
              "name": [
                "NYU Langone Medical Center, New York, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tsirigos", 
            "givenName": "Aristotelis", 
            "id": "sg:person.01321530670.66", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321530670.66"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Universit\u00e4tsmedizin G\u00f6ttingen", 
              "id": "https://www.grid.ac/institutes/grid.411984.1", 
              "name": [
                "Institute of Neuropathology, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Br\u00fcck", 
            "givenName": "Wolfgang", 
            "id": "sg:person.0705717164.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705717164.41"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Luzerner Kantonsspital", 
              "id": "https://www.grid.ac/institutes/grid.413354.4", 
              "name": [
                "Division of Oncology, Luzerner Kantonsspital, Luzern, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hofer", 
            "givenName": "Silvia", 
            "id": "sg:person.01056344227.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056344227.56"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Centre Mannheim", 
              "id": "https://www.grid.ac/institutes/grid.411778.c", 
              "name": [
                "Department of Neurosurgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Brehmer", 
            "givenName": "Stefanie", 
            "id": "sg:person.01226707144.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226707144.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Centre Mannheim", 
              "id": "https://www.grid.ac/institutes/grid.411778.c", 
              "name": [
                "Department of Neurosurgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Seiz-Rosenhagen", 
            "givenName": "Marcel", 
            "id": "sg:person.01006163216.47", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006163216.47"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Centre Mannheim", 
              "id": "https://www.grid.ac/institutes/grid.411778.c", 
              "name": [
                "Department of Neurosurgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "H\u00e4nggi", 
            "givenName": "Daniel", 
            "id": "sg:person.01051416514.73", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051416514.73"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Duisburg-Essen", 
              "id": "https://www.grid.ac/institutes/grid.5718.b", 
              "name": [
                "Institut f\u00fcr Neuropathologie, Evangelisches Krankenhaus Bielefeld gGmbH, Bielefeld, Germany", 
                "Institut f\u00fcr Neuropathologie, Universit\u00e4tskinikum Essen, Essen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hans", 
            "givenName": "Volkmar", 
            "id": "sg:person.01016616471.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016616471.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital M\u00fcnster", 
              "id": "https://www.grid.ac/institutes/grid.16149.3b", 
              "name": [
                "Institute of Neuropathology, University Hospital M\u00fcnster, M\u00fcnster, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rozsnoki", 
            "givenName": "Stephanie", 
            "id": "sg:person.013420042021.61", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013420042021.61"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Melbourne", 
              "id": "https://www.grid.ac/institutes/grid.1008.9", 
              "name": [
                "Children\u2019s Cancer Centre, Royal Children\u2019s Hospital, University of Melbourne, Melbourne, Victoria, Australia", 
                "Murdoch Children\u2019s Research Institute, University of Melbourne, Melbourne, Victoria, Australia", 
                "Department of Pediatrics, University of Melbourne, Melbourne, Victoria, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hansford", 
            "givenName": "Jordan R.", 
            "id": "sg:person.01276006465.63", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276006465.63"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Institute for Pathology, Katharinenhospital Stuttgart, Stuttgart, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kohlhof", 
            "givenName": "Patricia", 
            "id": "sg:person.014632224334.19", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014632224334.19"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Pathology, Odense University Hospital, Department of Clinical Research, University of Southern Denmark, Odense, Denmark"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kristensen", 
            "givenName": "Bjarne W.", 
            "id": "sg:person.0732205122.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732205122.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University College London", 
              "id": "https://www.grid.ac/institutes/grid.83440.3b", 
              "name": [
                "University College London Cancer Institute and University College London Hospitals, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lechner", 
            "givenName": "Matt", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Virginia", 
              "id": "https://www.grid.ac/institutes/grid.27755.32", 
              "name": [
                "Department of Pathology, University of Virginia, Charlottesville, Virginia, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lopes", 
            "givenName": "Beatriz", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Otto-von-Guericke University Magdeburg", 
              "id": "https://www.grid.ac/institutes/grid.5807.a", 
              "name": [
                "Institute of Neuropathology, Otto-von-Guericke-University, Magdeburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mawrin", 
            "givenName": "Christian", 
            "id": "sg:person.01143304676.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143304676.41"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Universit\u00e4tsklinikum des Saarlandes", 
              "id": "https://www.grid.ac/institutes/grid.411937.9", 
              "name": [
                "Department of Neurosurgery, University Hospital Saarland, Homburg, Saar, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ketter", 
            "givenName": "Ralf", 
            "id": "sg:person.01260652230.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260652230.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kulozik", 
            "givenName": "Andreas", 
            "id": "sg:person.01022515007.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022515007.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Miami Children's Hospital", 
              "id": "https://www.grid.ac/institutes/grid.415486.a", 
              "name": [
                "Nicklaus Children\u2019s Hospital Brain Institute, Miami, Florida 33155, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Khatib", 
            "givenName": "Ziad", 
            "id": "sg:person.01257065704.47", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257065704.47"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Berlin Institute of Health", 
              "id": "https://www.grid.ac/institutes/grid.484013.a", 
              "name": [
                "Charit\u00e9 \u2014 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany", 
                "Cluster of Excellence, NeuroCure, Berlin, Germany", 
                "Berlin Institute of Health (BIH), Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Heppner", 
            "givenName": "Frank", 
            "id": "sg:person.01153074764.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153074764.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Charit\u00e9 \u2014 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Koch", 
            "givenName": "Arend", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "H\u00f4pital Pierre Wertheimer", 
              "id": "https://www.grid.ac/institutes/grid.414243.4", 
              "name": [
                "D\u00e9partement de Pathologie et Neuropathologie, H\u00f4pital Neurologique, Hospices Civils de Lyon, Lyon, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jouvet", 
            "givenName": "Anne", 
            "id": "sg:person.0705164767.49", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705164767.49"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cork University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.411916.a", 
              "name": [
                "Department of Neuropathology, Cork University Hospital, Cork, Ireland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Keohane", 
            "givenName": "Catherine", 
            "id": "sg:person.0706124160.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706124160.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Pathology, Ludwigsburg Hospital, Ludwigsburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "M\u00fchleisen", 
            "givenName": "Helmut", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Leipzig University", 
              "id": "https://www.grid.ac/institutes/grid.9647.c", 
              "name": [
                "Department of Neuropathology, Leipzig University, Leipzig, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mueller", 
            "givenName": "Wolf", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Queen's Hospital", 
              "id": "https://www.grid.ac/institutes/grid.415588.5", 
              "name": [
                "Department of Cellular Pathology, Queen\u2019s Hospital, Romford, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pohl", 
            "givenName": "Ute", 
            "id": "sg:person.0643116747.44", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643116747.44"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Freiburg", 
              "id": "https://www.grid.ac/institutes/grid.5963.9", 
              "name": [
                "Institute of Neuropathology, Medical Center\u2013University of Freiburg, Faculty of Medicine, University of Freiburg, Germany", 
                "BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Prinz", 
            "givenName": "Marco", 
            "id": "sg:person.0732026257.14", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732026257.14"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Benner", 
            "givenName": "Axel", 
            "id": "sg:person.01366560070.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366560070.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zapatka", 
            "givenName": "Marc", 
            "id": "sg:person.01254147625.16", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01254147625.16"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Western Australia", 
              "id": "https://www.grid.ac/institutes/grid.1012.2", 
              "name": [
                "Department of Pediatric Oncology and Haematology, Princess Margaret Hospital for Children, GPO Box D184, Perth, Western Australia 6840, Australia", 
                "Telethon Kids Institute, University of Western Australia, PO Box 855, Perth, Western Australia 6872, Australia", 
                "School of Paediatrics and Child Health, University of Western Australia, GPO Box D184, Perth, Western Australia 6840, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gottardo", 
            "givenName": "Nicholas G.", 
            "id": "sg:person.0727411775.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727411775.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Charit\u00e9", 
              "id": "https://www.grid.ac/institutes/grid.6363.0", 
              "name": [
                "Department of Pediatric Oncology/Hematology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Driever", 
            "givenName": "Pablo Hern\u00e1iz", 
            "id": "sg:person.01201076245.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201076245.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Universit\u00e4tsmedizin G\u00f6ttingen", 
              "id": "https://www.grid.ac/institutes/grid.411984.1", 
              "name": [
                "Division of Pediatric Hematology and Oncology, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kramm", 
            "givenName": "Christof M.", 
            "id": "sg:person.01162773425.66", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162773425.66"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Carl von Ossietzky University of Oldenburg", 
              "id": "https://www.grid.ac/institutes/grid.5560.6", 
              "name": [
                "Department of Pediatrics and Pediatric Hematology/Oncology, Klinikum Oldenburg A\u00f6R, Medical Campus University Oldenburg, 26133 Oldenburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "M\u00fcller", 
            "givenName": "Hermann L.", 
            "id": "sg:person.01126205153.63", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126205153.63"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Center Hamburg-Eppendorf", 
              "id": "https://www.grid.ac/institutes/grid.13648.38", 
              "name": [
                "Department for Pediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rutkowski", 
            "givenName": "Stefan", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Center Hamburg-Eppendorf", 
              "id": "https://www.grid.ac/institutes/grid.13648.38", 
              "name": [
                "Department of Pediatric Oncology/Hematology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany", 
                "Department for Pediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "von Hoff", 
            "givenName": "Katja", 
            "id": "sg:person.01370425120.49", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370425120.49"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Children\u2019s Hospital Augsburg, Swabian Children\u2019s Cancer Centre, Augsburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fr\u00fchwald", 
            "givenName": "Michael C.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Children\u2019s Hospital Augsburg, Swabian Children\u2019s Cancer Centre, Augsburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gnekow", 
            "givenName": "Astrid", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Essen University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.410718.b", 
              "name": [
                "Pediatrics III, Pediatric Oncology and Hematology, University Hospital Essen, Essen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fleischhack", 
            "givenName": "Gudrun", 
            "id": "sg:person.0675511475.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675511475.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Essen University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.410718.b", 
              "name": [
                "Pediatrics III, Pediatric Oncology and Hematology, University Hospital Essen, Essen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tippelt", 
            "givenName": "Stephan", 
            "id": "sg:person.01061264270.01", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061264270.01"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Bonn", 
              "id": "https://www.grid.ac/institutes/grid.15090.3d", 
              "name": [
                "Department of Pediatric Hematology/Oncology, University of Bonn Medical Center, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Calaminus", 
            "givenName": "Gabriele", 
            "id": "sg:person.0750677602.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750677602.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of W\u00fcrzburg", 
              "id": "https://www.grid.ac/institutes/grid.8379.5", 
              "name": [
                "Department of Neuropathology, Insitute of Pathology, Comprehensive Cancer Center (CCC) Mainfranken, University of W\u00fcrzburg, W\u00fcrzburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Monoranu", 
            "givenName": "Camelia-Maria", 
            "id": "sg:person.0774642353.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774642353.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of California, San Francisco", 
              "id": "https://www.grid.ac/institutes/grid.266102.1", 
              "name": [
                "Department of Pathology, University of California San Francisco, San Francisco, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Perry", 
            "givenName": "Arie", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute of Cancer Research", 
              "id": "https://www.grid.ac/institutes/grid.18886.3f", 
              "name": [
                "Division of Molecular Pathology, Institute of Cancer Research, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jones", 
            "givenName": "Chris", 
            "id": "sg:person.0707750521.75", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707750521.75"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Great Ormond Street Hospital for Children NHS Foundation Trust", 
              "id": "https://www.grid.ac/institutes/grid.424537.3", 
              "name": [
                "Developmental Biology and Cancer Programme, UCL Great Ormond Street Institute of Child Health and Histopathology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jacques", 
            "givenName": "Thomas S.", 
            "id": "sg:person.01057011740.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057011740.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Radlwimmer", 
            "givenName": "Bernhard", 
            "id": "sg:person.0642756445.92", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642756445.92"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Department of Neuropathology, University of Bonn, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gessi", 
            "givenName": "Marco", 
            "id": "sg:person.01256065541.28", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256065541.28"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Department of Neuropathology, University of Bonn, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pietsch", 
            "givenName": "Torsten", 
            "id": "sg:person.01334206401.15", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01334206401.15"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Bonn", 
              "id": "https://www.grid.ac/institutes/grid.10388.32", 
              "name": [
                "Medical Faculty, University of Bonn Medical School, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schramm", 
            "givenName": "Johannes", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Neurosurgery, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schackert", 
            "givenName": "Gabriele", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Center Hamburg-Eppendorf", 
              "id": "https://www.grid.ac/institutes/grid.13648.38", 
              "name": [
                "Department of Neurosurgery, University Hospital Hamburg-Eppendorf, Hamburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Westphal", 
            "givenName": "Manfred", 
            "id": "sg:person.0703422661.29", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0703422661.29"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, Heinrich Heine University D\u00fcsseldorf, D\u00fcsseldorf, Germany", 
                "German Cancer Consortium (DKTK), partner site Essen/D\u00fcsseldorf, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Reifenberger", 
            "givenName": "Guido", 
            "id": "sg:person.07524506162.54", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07524506162.54"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "VU University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.16872.3a", 
              "name": [
                "Department of Pathology, Princess M\u00e1xima Center for Pediatric Oncology and University Medical Center Utrecht, Utrecht, The Netherlands", 
                "Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wesseling", 
            "givenName": "Pieter", 
            "id": "sg:person.01252521363.91", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252521363.91"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Zurich", 
              "id": "https://www.grid.ac/institutes/grid.7400.3", 
              "name": [
                "Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Weller", 
            "givenName": "Michael", 
            "id": "sg:person.0744526353.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744526353.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cambridge", 
              "id": "https://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "Department of Pathology, Division of Molecular Histopathology, University of Cambridge, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Collins", 
            "givenName": "Vincent Peter", 
            "id": "sg:person.0600656007.06", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600656007.06"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Neuropathological Institute, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bl\u00fcmcke", 
            "givenName": "Ingmar", 
            "id": "sg:person.0717255005.87", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717255005.87"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bendszus", 
            "givenName": "Martin", 
            "id": "sg:person.0763515656.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763515656.31"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Debus", 
            "givenName": "J\u00fcrgen", 
            "id": "sg:person.013541325272.97", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013541325272.97"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Toronto", 
              "id": "https://www.grid.ac/institutes/grid.17063.33", 
              "name": [
                "Department of Pediatrics, Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Huang", 
            "givenName": "Annie", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "McGill University", 
              "id": "https://www.grid.ac/institutes/grid.14709.3b", 
              "name": [
                "Division of Hematology/Oncology, McGill University, Montreal, Quebec, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jabado", 
            "givenName": "Nada", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "St. Jude Children's Research Hospital", 
              "id": "https://www.grid.ac/institutes/grid.240871.8", 
              "name": [
                "Department of Developmental Neurobiology, St Jude Children\u2019s Research Hospital, Memphis, Tennessee, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Northcott", 
            "givenName": "Paul A.", 
            "id": "sg:person.010563327577.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010563327577.08"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital M\u00fcnster", 
              "id": "https://www.grid.ac/institutes/grid.16149.3b", 
              "name": [
                "Institute of Neuropathology, University Hospital M\u00fcnster, M\u00fcnster, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Paulus", 
            "givenName": "Werner", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "St. Jude Children's Research Hospital", 
              "id": "https://www.grid.ac/institutes/grid.240871.8", 
              "name": [
                "Department of Oncology, St Jude Children\u2019s Research Hospital, Memphis, Tennessee, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gajjar", 
            "givenName": "Amar", 
            "id": "sg:person.0605704743.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605704743.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "St. Jude Children's Research Hospital", 
              "id": "https://www.grid.ac/institutes/grid.240871.8", 
              "name": [
                "Department of Oncology, St Jude Children\u2019s Research Hospital, Memphis, Tennessee, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Robinson", 
            "givenName": "Giles W.", 
            "id": "sg:person.01242105220.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242105220.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Toronto", 
              "id": "https://www.grid.ac/institutes/grid.17063.33", 
              "name": [
                "Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Taylor", 
            "givenName": "Michael D.", 
            "id": "sg:person.012731463207.92", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012731463207.92"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University College London", 
              "id": "https://www.grid.ac/institutes/grid.83440.3b", 
              "name": [
                "Division of Neuropathology, UCL Hospitals, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK", 
                "Department of Molecular Neuroscience, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK", 
                "Department of Neurodegeneration, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jaunmuktane", 
            "givenName": "Zane", 
            "id": "sg:person.0774443310.36", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774443310.36"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Burdenko Neurosurgery Institute", 
              "id": "https://www.grid.ac/institutes/grid.418542.e", 
              "name": [
                "NN Burdenko Neurosurgical Institute, Moscow, Russia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ryzhova", 
            "givenName": "Marina", 
            "id": "sg:person.01220632656.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220632656.30"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Neurology, Universit\u00e4tsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Platten", 
            "givenName": "Michael", 
            "id": "sg:person.01207421574.89", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207421574.89"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Unterberg", 
            "givenName": "Andreas", 
            "id": "sg:person.011341621677.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011341621677.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wick", 
            "givenName": "Wolfgang", 
            "id": "sg:person.01135120445.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01135120445.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Karajannis", 
            "givenName": "Matthias A.", 
            "id": "sg:person.01161510677.60", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161510677.60"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Laboratoire National de Sant\u00e9", 
              "id": "https://www.grid.ac/institutes/grid.419123.c", 
              "name": [
                "Institute of Neurology (Edinger Institute), Goethe-University Frankfurt am Main, Frankfurt am Main, Germany", 
                "German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, German Cancer Research Center (DKFZ) Heidelberg, Germany", 
                "NORLUX Neuro-Oncology Laboratory, Luxembourg Institute of Health (LIH), Luxembourg, Luxembourg", 
                "Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg, Luxembourg", 
                "Laboratoire national de sant\u00e9 (LNS), Dudelange, Luxembourg", 
                "Luxembourg Centre of Neuropathology (LCNP), Luxembourg, Luxembourg"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mittelbronn", 
            "givenName": "Michel", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Giessen", 
              "id": "https://www.grid.ac/institutes/grid.8664.c", 
              "name": [
                "Institute of Neuropathology, University of Giessen, Giessen, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Acker", 
            "givenName": "Till", 
            "id": "sg:person.01330376505.46", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330376505.46"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hannover Medical School", 
              "id": "https://www.grid.ac/institutes/grid.10423.34", 
              "name": [
                "Department of Neuropathology, Hannover Medical School (MHH), Hannover, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hartmann", 
            "givenName": "Christian", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Toronto", 
              "id": "https://www.grid.ac/institutes/grid.17063.33", 
              "name": [
                "Department of Pathology, University of Toronto, Toronto, Ontario, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Aldape", 
            "givenName": "Kenneth", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Center Hamburg-Eppendorf", 
              "id": "https://www.grid.ac/institutes/grid.13648.38", 
              "name": [
                "Center for Neuropathology and Prion Research, Ludwig-Maximilians-University, Munich, Germany", 
                "Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany", 
                "Research Institute Children\u2019s Cancer Center, Hamburg, Germany", 
                "Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sch\u00fcller", 
            "givenName": "Ulrich", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Sozialstiftung Bamberg", 
              "id": "https://www.grid.ac/institutes/grid.419802.6", 
              "name": [
                "Neuropathological Institute, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany", 
                "Section Neuropathology, Institute of Pathology, Sozialstiftung Bamberg, Klinikum am Bruderwald, Bamberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Buslei", 
            "givenName": "Rolf", 
            "id": "sg:person.0662562774.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662562774.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lichter", 
            "givenName": "Peter", 
            "id": "sg:person.01243467607.83", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243467607.83"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kool", 
            "givenName": "Marcel", 
            "id": "sg:person.01206710443.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206710443.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Herold-Mende", 
            "givenName": "Christel", 
            "id": "sg:person.0767624634.57", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767624634.57"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "St. Jude Children's Research Hospital", 
              "id": "https://www.grid.ac/institutes/grid.240871.8", 
              "name": [
                "Department of Pathology, St Jude Children\u2019s Research Hospital, Memphis, Tennessee, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ellison", 
            "givenName": "David W.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital M\u00fcnster", 
              "id": "https://www.grid.ac/institutes/grid.16149.3b", 
              "name": [
                "Institute of Neuropathology, University Hospital M\u00fcnster, M\u00fcnster, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hasselblatt", 
            "givenName": "Martin", 
            "id": "sg:person.01137070015.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137070015.52"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "New York University Langone Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.240324.3", 
              "name": [
                "Division of Neuropathology, Department of Pathology, NYU Langone Medical Center, New York, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Snuderl", 
            "givenName": "Matija", 
            "id": "sg:person.01220310166.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220310166.56"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University College London", 
              "id": "https://www.grid.ac/institutes/grid.83440.3b", 
              "name": [
                "Division of Neuropathology, UCL Hospitals, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK", 
                "Department of Neurodegeneration, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Brandner", 
            "givenName": "Sebastian", 
            "id": "sg:person.01255521146.21", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255521146.21"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Korshunov", 
            "givenName": "Andrey", 
            "id": "sg:person.013472071457.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013472071457.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Cancer Research Center", 
              "id": "https://www.grid.ac/institutes/grid.7497.d", 
              "name": [
                "Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany", 
                "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "von Deimling", 
            "givenName": "Andreas", 
            "id": "sg:person.0627772654.33", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627772654.33"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Heidelberg", 
              "id": "https://www.grid.ac/institutes/grid.5253.1", 
              "name": [
                "Hopp Children\u2019s Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany", 
                "Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany", 
                "Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pfister", 
            "givenName": "Stefan M.", 
            "id": "sg:person.01105171247.76", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105171247.76"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1002/bimj.201300083", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002786001"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1010920819831", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003442924", 
              "https://doi.org/10.1023/a:1010920819831"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004871541", 
              "https://doi.org/10.1038/nature13108"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gr.119867.110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006265010"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-013-1126-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008994603", 
              "https://doi.org/10.1007/s00401-013-1126-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-013-1126-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008994603", 
              "https://doi.org/10.1007/s00401-013-1126-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.0030161", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009683731"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-013-1124-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009865592", 
              "https://doi.org/10.1007/s00401-013-1124-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2682", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009937083", 
              "https://doi.org/10.1038/ng.2682"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2203", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010515132", 
              "https://doi.org/10.1038/nbt.2203"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s40478-016-0287-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010875827", 
              "https://doi.org/10.1186/s40478-016-0287-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-015-1454-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011884053", 
              "https://doi.org/10.1007/s00401-015-1454-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ipm.2009.03.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012321154"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2015.12.028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012801617"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-015-1519-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014983828", 
              "https://doi.org/10.1007/s00401-015-1519-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-014-1315-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015534862", 
              "https://doi.org/10.1007/s00401-014-1315-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-013-1228-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018270959", 
              "https://doi.org/10.1007/s00401-013-1228-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-013-1228-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018270959", 
              "https://doi.org/10.1007/s00401-013-1228-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13268", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019709850", 
              "https://doi.org/10.1038/nature13268"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jmoldx.2015.11.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022061687"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jmoldx.2015.11.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022061687"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jmoldx.2015.11.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022061687"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jmoldx.2015.11.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022061687"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/bimj.201300296", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024107762"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1010933404324", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024739340", 
              "https://doi.org/10.1023/a:1010933404324"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2016.01.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024874051"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-015-1409-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028192418", 
              "https://doi.org/10.1007/s00401-015-1409-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/bioinformatics/btr434", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033481343"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/bpa.12228", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033964652"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccell.2015.04.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034457047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa1402121", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034690235"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/bioinformatics/btu049", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036696259"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/neuonc/nov322", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036733188"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1477-5751-10-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038490809", 
              "https://doi.org/10.1186/1477-5751-10-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11284", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039302414", 
              "https://doi.org/10.1038/nature11284"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1470-2045(16)30297-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040407721"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccell.2016.02.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042025420"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/bpa.12282", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045798118"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-015-1493-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047152106", 
              "https://doi.org/10.1007/s00401-015-1493-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0808709105", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047872370"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-014-1276-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048635299", 
              "https://doi.org/10.1007/s00401-014-1276-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-014-1276-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048635299", 
              "https://doi.org/10.1007/s00401-014-1276-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00401-010-0725-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049160565", 
              "https://doi.org/10.1007/s00401-010-0725-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.3252", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050075164", 
              "https://doi.org/10.1038/nmeth.3252"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2083", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052071569", 
              "https://doi.org/10.1038/nbt.2083"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccr.2012.08.024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052838309"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1175/1520-0493(1950)078<0001:vofeit>2.0.co;2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063450417"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18637/jss.v033.i01", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068672496"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18637/jss.v033.i01", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068672496"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/icmla.2008.107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1093639064"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7551/mitpress/1113.001.0001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1110614771"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2018-03", 
        "datePublishedReg": "2018-03-01", 
        "description": "Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-with substantial inter-observer variability in the histopathological diagnosis of many tumour types. Here we present a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and demonstrate its application in a routine diagnostic setting. We show that the availability of this method may have a substantial impact on diagnostic precision compared to standard methods, resulting in a change of diagnosis in up to 12% of prospective cases. For broader accessibility, we have designed a free online classifier tool, the use of which does not require any additional onsite data processing. Our results provide a blueprint for the generation of machine-learning-based tumour classifiers across other cancer entities, with the potential to fundamentally transform tumour pathology.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/nature26000", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2682838", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2438793", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1018957", 
            "issn": [
              "0090-0028", 
              "1476-4687"
            ], 
            "name": "Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "7697", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "555"
          }
        ], 
        "name": "DNA methylation-based classification of central nervous system tumours", 
        "pagination": "469", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "a37016d6cabefd42cffeb1af8314da008311b335778d348d02de652218157a70"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "29539639"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0410462"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nature26000"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1101533700"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nature26000", 
          "https://app.dimensions.ai/details/publication/pub.1101533700"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T12:27", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87117_00000001.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://www.nature.com/articles/nature26000"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature26000'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature26000'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature26000'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature26000'


     

    This table displays all metadata directly associated to this object as RDF triples.

    1527 TRIPLES      21 PREDICATES      90 URIs      38 LITERALS      26 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nature26000 schema:about N04f8cdb72e2e40d09bf156ea3f95b8c5
    2 N04f9cb7928b741ae8b0bee327be8febe
    3 N0b7ccaa1f098450ca10cf69459d72ead
    4 N1468bcf779f54b7aa7883c5f0b755ee0
    5 N437641875f1745f983d6ddd1abaafca0
    6 N4afe5b1d97374097b0a9c0a7b2a47f70
    7 N54a0f196369d4131b0ac5605295de2eb
    8 N789bb777b54c49a8b06163d3fa0451bd
    9 N7f562d05e8d04339a778aad0b9dc0922
    10 N8d789c8e396645a9b42827fc93f341b2
    11 Nad5f7a2f0e6540978945a6f70b338c32
    12 Nbab6f74208514f549e5076952f9b8fad
    13 Nbca888b23a194b9698e5c819e66a6549
    14 Nca68210cadc24624a775b8393e454e21
    15 Ndebd2e61600846c89c21667afdeb7147
    16 Nf04ad730bf3a4789b4260f0626ddcd30
    17 Nf79544624e9d42dfa84f03b29d244664
    18 anzsrc-for:11
    19 anzsrc-for:1112
    20 schema:author N067f2421c9e3451ea1ab1ca3b340ec8d
    21 schema:citation sg:pub.10.1007/s00401-010-0725-7
    22 sg:pub.10.1007/s00401-013-1124-7
    23 sg:pub.10.1007/s00401-013-1126-5
    24 sg:pub.10.1007/s00401-013-1228-0
    25 sg:pub.10.1007/s00401-014-1276-0
    26 sg:pub.10.1007/s00401-014-1315-x
    27 sg:pub.10.1007/s00401-015-1409-0
    28 sg:pub.10.1007/s00401-015-1454-8
    29 sg:pub.10.1007/s00401-015-1493-1
    30 sg:pub.10.1007/s00401-015-1519-8
    31 sg:pub.10.1023/a:1010920819831
    32 sg:pub.10.1023/a:1010933404324
    33 sg:pub.10.1038/nature11284
    34 sg:pub.10.1038/nature13108
    35 sg:pub.10.1038/nature13268
    36 sg:pub.10.1038/nbt.2083
    37 sg:pub.10.1038/nbt.2203
    38 sg:pub.10.1038/ng.2682
    39 sg:pub.10.1038/nmeth.3252
    40 sg:pub.10.1186/1477-5751-10-7
    41 sg:pub.10.1186/s40478-016-0287-6
    42 https://doi.org/10.1002/bimj.201300083
    43 https://doi.org/10.1002/bimj.201300296
    44 https://doi.org/10.1016/j.ccell.2015.04.002
    45 https://doi.org/10.1016/j.ccell.2016.02.001
    46 https://doi.org/10.1016/j.ccr.2012.08.024
    47 https://doi.org/10.1016/j.cell.2015.12.028
    48 https://doi.org/10.1016/j.cell.2016.01.015
    49 https://doi.org/10.1016/j.ipm.2009.03.002
    50 https://doi.org/10.1016/j.jmoldx.2015.11.009
    51 https://doi.org/10.1016/s1470-2045(16)30297-2
    52 https://doi.org/10.1056/nejmoa1402121
    53 https://doi.org/10.1073/pnas.0808709105
    54 https://doi.org/10.1093/bioinformatics/btr434
    55 https://doi.org/10.1093/bioinformatics/btu049
    56 https://doi.org/10.1093/neuonc/nov322
    57 https://doi.org/10.1101/gr.119867.110
    58 https://doi.org/10.1109/icmla.2008.107
    59 https://doi.org/10.1111/bpa.12228
    60 https://doi.org/10.1111/bpa.12282
    61 https://doi.org/10.1175/1520-0493(1950)078<0001:vofeit>2.0.co;2
    62 https://doi.org/10.1371/journal.pgen.0030161
    63 https://doi.org/10.18637/jss.v033.i01
    64 https://doi.org/10.7551/mitpress/1113.001.0001
    65 schema:datePublished 2018-03
    66 schema:datePublishedReg 2018-03-01
    67 schema:description Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-with substantial inter-observer variability in the histopathological diagnosis of many tumour types. Here we present a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and demonstrate its application in a routine diagnostic setting. We show that the availability of this method may have a substantial impact on diagnostic precision compared to standard methods, resulting in a change of diagnosis in up to 12% of prospective cases. For broader accessibility, we have designed a free online classifier tool, the use of which does not require any additional onsite data processing. Our results provide a blueprint for the generation of machine-learning-based tumour classifiers across other cancer entities, with the potential to fundamentally transform tumour pathology.
    68 schema:genre research_article
    69 schema:inLanguage en
    70 schema:isAccessibleForFree false
    71 schema:isPartOf N09ab10b0344f4783a585f68277baf696
    72 Ne1e61aea4e314409be7e89ded402323c
    73 sg:journal.1018957
    74 schema:name DNA methylation-based classification of central nervous system tumours
    75 schema:pagination 469
    76 schema:productId N1a1faaf627f240b48923184e8bc1ada5
    77 N4a90a2fe450c426ba0b3a90fe435be6b
    78 N66ef8641c1d0478198f28aa5a95810ce
    79 Nbc6d164972104c98bd50c75973790d34
    80 Nc3e0d5a8be034581bae47b3a0f654a5d
    81 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101533700
    82 https://doi.org/10.1038/nature26000
    83 schema:sdDatePublished 2019-04-11T12:27
    84 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    85 schema:sdPublisher Nec625cf234e04a26b4bf0d31342b3100
    86 schema:url https://www.nature.com/articles/nature26000
    87 sgo:license sg:explorer/license/
    88 sgo:sdDataset articles
    89 rdf:type schema:ScholarlyArticle
    90 N002281d05cd240ffa7ee6160bc1c60e6 rdf:first sg:person.0727411775.32
    91 rdf:rest Ndc3cd9d239b3465abf741ddd9ceefd0b
    92 N00fa476f3bde479698e6815b8ba3a39c rdf:first sg:person.01242105220.02
    93 rdf:rest N1341522eb6b348bcad9362e6fa64c3df
    94 N020b571308964e4d9f8f1b155ac9623b rdf:first sg:person.01255521146.21
    95 rdf:rest N0a90a3fb8390406eb1ddf227272d2c9f
    96 N02658a70c747479282ae2aa520843915 rdf:first sg:person.0732026257.14
    97 rdf:rest Nf250f3173e0549909979df331e77f97c
    98 N04f8cdb72e2e40d09bf156ea3f95b8c5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    99 schema:name Humans
    100 rdf:type schema:DefinedTerm
    101 N04f9cb7928b741ae8b0bee327be8febe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    102 schema:name Middle Aged
    103 rdf:type schema:DefinedTerm
    104 N05911929ce8545c6b396ec6aa580a58d rdf:first sg:person.01334206401.15
    105 rdf:rest Nc993eea4cf514895bfdac62b77a8dab8
    106 N067f2421c9e3451ea1ab1ca3b340ec8d rdf:first sg:person.01043273753.26
    107 rdf:rest Neec4726426cd4fddad39fbd8bbb73395
    108 N06ebf2749fc64839853db52a7fd7239f rdf:first sg:person.01016616471.07
    109 rdf:rest Ne28a3ef58ceb4cb6969f56e26b7b3441
    110 N077650fac6fb4c16917db33675341cfb rdf:first sg:person.01051416514.73
    111 rdf:rest N06ebf2749fc64839853db52a7fd7239f
    112 N0956b5c40f054fb58c18b4383b5bf860 schema:affiliation https://www.grid.ac/institutes/grid.13648.38
    113 schema:familyName Schüller
    114 schema:givenName Ulrich
    115 rdf:type schema:Person
    116 N09ab10b0344f4783a585f68277baf696 schema:issueNumber 7697
    117 rdf:type schema:PublicationIssue
    118 N0a90a3fb8390406eb1ddf227272d2c9f rdf:first sg:person.013472071457.40
    119 rdf:rest N5dd3111bf6ac45b9a076ec8019c14371
    120 N0b7ccaa1f098450ca10cf69459d72ead schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    121 schema:name Male
    122 rdf:type schema:DefinedTerm
    123 N0d163d46111a41beaf66e6a4b2e014a1 schema:name Institute of Neuropathology, Medical Center–University of Freiburg, Faculty of Medicine, University of Freiburg, Germany
    124 rdf:type schema:Organization
    125 N0d3072d66f50431899d34a367b90fc0c schema:affiliation https://www.grid.ac/institutes/grid.83440.3b
    126 schema:familyName Lechner
    127 schema:givenName Matt
    128 rdf:type schema:Person
    129 N1341522eb6b348bcad9362e6fa64c3df rdf:first sg:person.012731463207.92
    130 rdf:rest N37e4b93702794cc99cc92886e9b98e25
    131 N1468bcf779f54b7aa7883c5f0b755ee0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    132 schema:name Infant
    133 rdf:type schema:DefinedTerm
    134 N154a4ded9f1d40ecb5b000e880ba73bf schema:affiliation https://www.grid.ac/institutes/grid.27755.32
    135 schema:familyName Lopes
    136 schema:givenName Beatriz
    137 rdf:type schema:Person
    138 N1a1faaf627f240b48923184e8bc1ada5 schema:name readcube_id
    139 schema:value a37016d6cabefd42cffeb1af8314da008311b335778d348d02de652218157a70
    140 rdf:type schema:PropertyValue
    141 N1ceff24e7fa94ecfa36fa205a0367d1d rdf:first N722cd173da5d4973a85b3b4c94151be1
    142 rdf:rest Nf861fbb4fbb54b12bcd6e1afc4270325
    143 N1e01131b676a46f69b08b122a96d92c5 rdf:first sg:person.01206710443.02
    144 rdf:rest Nf25e38d05d444b21a9d4ce5422c92894
    145 N1e8d7c970f6e4c4aa48788323c85a329 schema:name Charité — Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany
    146 rdf:type schema:Organization
    147 N215d12d1542b4b52adc23406329546e4 rdf:first Nfaae96d647d5414890e00e6ce589b770
    148 rdf:rest Nc4ab707ea3eb4db1b6eed3236e201028
    149 N2201b6569983429dbf973889b02cac0e schema:affiliation https://www.grid.ac/institutes/grid.9647.c
    150 schema:familyName Mueller
    151 schema:givenName Wolf
    152 rdf:type schema:Person
    153 N23d6b2cf23534703b45cd0616381c239 rdf:first sg:person.0642756445.92
    154 rdf:rest Na2d22824d6c54ecda4f7b365d880e39c
    155 N257db6a66ee34a6f96ee70a41376a0cd rdf:first sg:person.01126205153.63
    156 rdf:rest Nc22e5a34da2b4dbaaf42a74f9a2274a5
    157 N263445fb08fb4af885e9f597f1dac72a schema:name Neuropathological Institute, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany
    158 rdf:type schema:Organization
    159 N271f8ed0c32b4736ad4bb7aca7ca5826 schema:affiliation https://www.grid.ac/institutes/grid.10388.32
    160 schema:familyName Schramm
    161 schema:givenName Johannes
    162 rdf:type schema:Person
    163 N272f930ea92940d9b269c5f0d0d4328d rdf:first sg:person.0706124160.23
    164 rdf:rest N6449f2b393ed4c5397ce49f67d706a17
    165 N28152708746346488b4ee8f4b89c48e3 rdf:first sg:person.0721513443.35
    166 rdf:rest N41c143d5087d4f15b4920ddafd26df16
    167 N294d6efd47c348a590355f2b226b93b8 rdf:first sg:person.014632224334.19
    168 rdf:rest N9c21849a83504b51aef171f5be37a8f2
    169 N2f273b8efd524f8e92238387a6438695 schema:name Children’s Hospital Augsburg, Swabian Children’s Cancer Centre, Augsburg, Germany
    170 rdf:type schema:Organization
    171 N2f795c2989dc4d609cda42f3fc095c3b schema:affiliation https://www.grid.ac/institutes/grid.240871.8
    172 schema:familyName Ellison
    173 schema:givenName David W.
    174 rdf:type schema:Person
    175 N31d1fffb1a5c4d568a61aa1272927a96 rdf:first sg:person.01064137712.31
    176 rdf:rest Ne574a92dd4654328aec0e24c94d8e7df
    177 N33857418d9e249c89f38f66b18330759 rdf:first Ndad3c12c1a9446e8bccc24f60c2ad608
    178 rdf:rest Nd4dd2b2ddc894f47b7d56851d8e1b803
    179 N33a30c31e06d42aa98d5c1dd0e3d8a9e rdf:first sg:person.0610463215.17
    180 rdf:rest N8eb16476419b4cc4b7baf1ee434e91f9
    181 N347e972d840548ca8673e6f589c73c8e rdf:first sg:person.01252521363.91
    182 rdf:rest N36cb0058da104170a7917e871b95e02b
    183 N3561f26d6da54cdba8869bf4630515c7 rdf:first sg:person.01243467607.83
    184 rdf:rest N1e01131b676a46f69b08b122a96d92c5
    185 N36cb0058da104170a7917e871b95e02b rdf:first sg:person.0744526353.25
    186 rdf:rest Nfe6bc39366a2442a90d30c7087f9001c
    187 N36f25b3b8e41412d84f0c0cc85333c2f rdf:first sg:person.011341621677.42
    188 rdf:rest Nc3352c607ee4466d9c7934cfdfa452ea
    189 N37e4b93702794cc99cc92886e9b98e25 rdf:first sg:person.0774443310.36
    190 rdf:rest Nb154b002ed424c23950fe1df53ef5e11
    191 N3a814faa31524e90a5607b625f602cb7 rdf:first sg:person.0675572337.13
    192 rdf:rest N31d1fffb1a5c4d568a61aa1272927a96
    193 N3b576cd427b047a29e34c91a53c4b456 rdf:first sg:person.01161510677.60
    194 rdf:rest N33857418d9e249c89f38f66b18330759
    195 N3bebbe0988414b73bf749b6bb946d24f rdf:first N154a4ded9f1d40ecb5b000e880ba73bf
    196 rdf:rest Nc6eb610816c34b28b24ff1ca95d4273a
    197 N3d2641daa1d44e2491dbacdfbe016e37 schema:affiliation N263445fb08fb4af885e9f597f1dac72a
    198 schema:familyName Coras
    199 schema:givenName Roland
    200 rdf:type schema:Person
    201 N3ebe554973ce48d2bf5dff9637a9d045 schema:name Neuropathological Institute, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany
    202 rdf:type schema:Organization
    203 N3ec6b95a731248bf8acc9333973cf9bd schema:name Children’s Hospital Augsburg, Swabian Children’s Cancer Centre, Augsburg, Germany
    204 rdf:type schema:Organization
    205 N41248fdc59654c2fb8871948f1b3ab39 rdf:first sg:person.0637473041.27
    206 rdf:rest N5c45e9d71d6941ab89cc27874ddb2ef4
    207 N41c143d5087d4f15b4920ddafd26df16 rdf:first sg:person.0600137763.92
    208 rdf:rest Ne477f6d38e92472fab6f6a062fc2e29d
    209 N4338c11fe84e48c38fdf6dcb958cdb06 rdf:first sg:person.0643116747.44
    210 rdf:rest N02658a70c747479282ae2aa520843915
    211 N437641875f1745f983d6ddd1abaafca0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    212 schema:name DNA Methylation
    213 rdf:type schema:DefinedTerm
    214 N461c6e2022a84719b1b202bf9ca169ae rdf:first sg:person.01235252033.21
    215 rdf:rest N75f48b02308b41659c761a720121c661
    216 N467d2be6a6384b668dfda85119a81577 rdf:first sg:person.01124352515.36
    217 rdf:rest Na248160e39a94c0fb75ae2afdf6275a3
    218 N4963198154c84fc0863f334b00f7771c rdf:first sg:person.01134175470.77
    219 rdf:rest Neb8bc1c9f02d4619976c3e533f174347
    220 N49a3e85849bd44cfb4cae8a6061a2864 rdf:first sg:person.01074367672.42
    221 rdf:rest Ndfc972de746a4bdd93667116b38ec4ff
    222 N4a8610dffce94b5c994e9cfd8afd64ea schema:name Neuropathological Institute, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany
    223 rdf:type schema:Organization
    224 N4a90a2fe450c426ba0b3a90fe435be6b schema:name dimensions_id
    225 schema:value pub.1101533700
    226 rdf:type schema:PropertyValue
    227 N4afe5b1d97374097b0a9c0a7b2a47f70 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    228 schema:name Child
    229 rdf:type schema:DefinedTerm
    230 N4bfdb5848dd64635a3ea50a69fc483df rdf:first sg:person.0773150274.84
    231 rdf:rest N590b15a6380d4d429bb55fab0fab3db7
    232 N4cd472a8299d48859774b3b15dafe92b rdf:first sg:person.0750677602.37
    233 rdf:rest N819cb702711b40a1ae00bfc11f4109be
    234 N4ce7f52832e14335ad65f7f0144ce3cd rdf:first sg:person.0605704743.40
    235 rdf:rest N00fa476f3bde479698e6815b8ba3a39c
    236 N4dd40373b0bd4f039725312466467a05 rdf:first sg:person.0607426433.30
    237 rdf:rest Ncb602b6cf6a94737b2e9444880f5417f
    238 N54a0f196369d4131b0ac5605295de2eb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    239 schema:name Female
    240 rdf:type schema:DefinedTerm
    241 N54de5b49555b4356a6ebcb1adf493e2f rdf:first sg:person.015355630434.80
    242 rdf:rest N5a4685e0a1df4bc2803f17f6faeb9007
    243 N55afc3f3863d4df3812a83accf7a5db5 schema:affiliation https://www.grid.ac/institutes/grid.14709.3b
    244 schema:familyName Jabado
    245 schema:givenName Nada
    246 rdf:type schema:Person
    247 N57c17e0dd03b4c41b4f322fb49470f0d rdf:first sg:person.01051617612.15
    248 rdf:rest N28152708746346488b4ee8f4b89c48e3
    249 N583719cb1e8841feac297e02e850891f rdf:first sg:person.01207421574.89
    250 rdf:rest N36f25b3b8e41412d84f0c0cc85333c2f
    251 N590b15a6380d4d429bb55fab0fab3db7 rdf:first sg:person.0742653406.25
    252 rdf:rest Nd690195161d546c5987ae4deb42ff26b
    253 N59d8ac0165544022be3d8239b722b8e2 rdf:first sg:person.01022515007.00
    254 rdf:rest N9c5e503cdfa3488ca1b6fca60e719b2c
    255 N5a4685e0a1df4bc2803f17f6faeb9007 rdf:first sg:person.0647670107.02
    256 rdf:rest Ncae90faefee04f71be8667e58683cdbf
    257 N5b0124d3662a49a396624f2d7b2ff214 rdf:first sg:person.01226707144.32
    258 rdf:rest N63593d18bca642ff92c7fe5371602cc0
    259 N5b0407cb299b4ce782b99b3d09a321e7 rdf:first sg:person.0653406766.10
    260 rdf:rest N4dd40373b0bd4f039725312466467a05
    261 N5bad239276d648f0a7a00614363b38dd rdf:first sg:person.0775160553.49
    262 rdf:rest Nf5b14fd579d44d8e95c067d96eb62500
    263 N5c45e9d71d6941ab89cc27874ddb2ef4 rdf:first sg:person.0743051543.84
    264 rdf:rest N215d12d1542b4b52adc23406329546e4
    265 N5dd3111bf6ac45b9a076ec8019c14371 rdf:first sg:person.0627772654.33
    266 rdf:rest Nd7564b506df34b8ca463aaa4dc697e14
    267 N5f372dea179a413892dedc46d81cdc6d schema:affiliation https://www.grid.ac/institutes/grid.16149.3b
    268 schema:familyName Paulus
    269 schema:givenName Werner
    270 rdf:type schema:Person
    271 N6030cccc92c04aa6baa90bdc346c05a6 rdf:first sg:person.01104073627.88
    272 rdf:rest N33a30c31e06d42aa98d5c1dd0e3d8a9e
    273 N63593d18bca642ff92c7fe5371602cc0 rdf:first sg:person.01006163216.47
    274 rdf:rest N077650fac6fb4c16917db33675341cfb
    275 N6449f2b393ed4c5397ce49f67d706a17 rdf:first Neb5fee885be14326b0696c4e047de433
    276 rdf:rest N7ff6425c731548ab930510446b35e096
    277 N66e0ac7966474116a132290d89db26e0 rdf:first N2f795c2989dc4d609cda42f3fc095c3b
    278 rdf:rest Ndcd9513497fd4b179961e43bfc6dccbc
    279 N66ef8641c1d0478198f28aa5a95810ce schema:name doi
    280 schema:value 10.1038/nature26000
    281 rdf:type schema:PropertyValue
    282 N66f19547c1cc48f19c6d5f987b96cebe rdf:first sg:person.01061264270.01
    283 rdf:rest N4cd472a8299d48859774b3b15dafe92b
    284 N6a64cebd98cc4f44bd47dccd57140b4f rdf:first sg:person.0705164767.49
    285 rdf:rest N272f930ea92940d9b269c5f0d0d4328d
    286 N6c536faf290d49599b348cceab8badd8 rdf:first sg:person.0675511475.98
    287 rdf:rest N66f19547c1cc48f19c6d5f987b96cebe
    288 N6e08e02f0a254f7c8d07f218e7aad997 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
    289 schema:familyName Aldape
    290 schema:givenName Kenneth
    291 rdf:type schema:Person
    292 N722cd173da5d4973a85b3b4c94151be1 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
    293 schema:familyName Huang
    294 schema:givenName Annie
    295 rdf:type schema:Person
    296 N72efb3de9dd74ec9a7e8632476b26777 rdf:first sg:person.0705717164.41
    297 rdf:rest Nf78bd08978e54ec48d77d198c2212c5a
    298 N75f48b02308b41659c761a720121c661 rdf:first N3d2641daa1d44e2491dbacdfbe016e37
    299 rdf:rest N4bfdb5848dd64635a3ea50a69fc483df
    300 N789bb777b54c49a8b06163d3fa0451bd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    301 schema:name Child, Preschool
    302 rdf:type schema:DefinedTerm
    303 N7a275641d0664d59bfa7dfdf3b9907f6 rdf:first N6e08e02f0a254f7c8d07f218e7aad997
    304 rdf:rest Nbda01b23ebf54529b05ce206f4cfe9a9
    305 N7d39e0628ba54fb8a11190e7a8abe551 rdf:first sg:person.01023212571.19
    306 rdf:rest Nde8a438c211a4a10a9ebb8b4de331ad0
    307 N7f562d05e8d04339a778aad0b9dc0922 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    308 schema:name Reproducibility of Results
    309 rdf:type schema:DefinedTerm
    310 N7ff6425c731548ab930510446b35e096 rdf:first N2201b6569983429dbf973889b02cac0e
    311 rdf:rest N4338c11fe84e48c38fdf6dcb958cdb06
    312 N817cfd556db24942868eaab7f6bf0f37 rdf:first sg:person.01276006465.63
    313 rdf:rest N294d6efd47c348a590355f2b226b93b8
    314 N81827f5ae26c48ff8f73157ba97596a5 rdf:first sg:person.01370425120.49
    315 rdf:rest N890cd90314e245ce95109d8b3bc39389
    316 N819cb702711b40a1ae00bfc11f4109be rdf:first sg:person.0774642353.25
    317 rdf:rest N890a657603154ae7928f76feca090292
    318 N85fa5d4eac73426bb15cd514c700faa7 rdf:first sg:person.01175561336.61
    319 rdf:rest Nf8b445fc36664d68a45a655c4b3a0434
    320 N890a657603154ae7928f76feca090292 rdf:first Nfec1d65a6c904b879d02792af1c53c3e
    321 rdf:rest Nece22ffc7ca743aa889e893d1d1a8d43
    322 N890cd90314e245ce95109d8b3bc39389 rdf:first Na6ddbc30e4b4448fa94eda56e1633c2f
    323 rdf:rest Nef0ea3af3b7b43d290a970724a03c453
    324 N8a6a4aa4c8c24b339db5008d48d3cbd5 rdf:first sg:person.01220310166.56
    325 rdf:rest N020b571308964e4d9f8f1b155ac9623b
    326 N8b78dcc8a3a14b1189a9bb9063511c89 rdf:first sg:person.01247463220.45
    327 rdf:rest Nd72720cf42264c81a64e1f20c1209247
    328 N8c5a41a20f7544c18b4f77450011b9ba rdf:first sg:person.013567220602.01
    329 rdf:rest Nd56e183243274b108ab69cd5ac08ed2e
    330 N8d789c8e396645a9b42827fc93f341b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    331 schema:name Aged
    332 rdf:type schema:DefinedTerm
    333 N8eb16476419b4cc4b7baf1ee434e91f9 rdf:first sg:person.01234464637.55
    334 rdf:rest N467d2be6a6384b668dfda85119a81577
    335 N90d7f387bea446c8ad35cac654c0c980 rdf:first N5f372dea179a413892dedc46d81cdc6d
    336 rdf:rest N4ce7f52832e14335ad65f7f0144ce3cd
    337 N9722b30669c5444ba3f0490193b7fb0e schema:affiliation N1e8d7c970f6e4c4aa48788323c85a329
    338 schema:familyName Koch
    339 schema:givenName Arend
    340 rdf:type schema:Person
    341 N9840edad74a64420ba1f9baffebce32b schema:affiliation N2f273b8efd524f8e92238387a6438695
    342 schema:familyName Gnekow
    343 schema:givenName Astrid
    344 rdf:type schema:Person
    345 N985d213d3ba04ed29ef5d9e910d717c2 schema:affiliation Na0a2ec1b9ea44c9dae09f3a11d744389
    346 schema:familyName Schackert
    347 schema:givenName Gabriele
    348 rdf:type schema:Person
    349 N98924501357a44d99a61db31eeceb69d rdf:first sg:person.01367420407.26
    350 rdf:rest Nddd88b33412e4d60a863c0edbf9a057a
    351 N98a0f99658af484a919b1864b1a981f5 schema:name Department of Pathology, Ludwigsburg Hospital, Ludwigsburg, Germany
    352 rdf:type schema:Organization
    353 N9c21849a83504b51aef171f5be37a8f2 rdf:first sg:person.0732205122.45
    354 rdf:rest Nacac795f54914efa941015c1f92a5b98
    355 N9c5e503cdfa3488ca1b6fca60e719b2c rdf:first sg:person.01257065704.47
    356 rdf:rest Nffebadaef8714042b48af48a42cdf48e
    357 Na0a2ec1b9ea44c9dae09f3a11d744389 schema:name Department of Neurosurgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
    358 rdf:type schema:Organization
    359 Na248160e39a94c0fb75ae2afdf6275a3 rdf:first sg:person.01153246175.48
    360 rdf:rest N5bad239276d648f0a7a00614363b38dd
    361 Na28650c51f3b4e09ad2e4f5eda6e0c2c schema:affiliation https://www.grid.ac/institutes/grid.240324.3
    362 schema:familyName Serrano
    363 schema:givenName Jonathan
    364 rdf:type schema:Person
    365 Na2d22824d6c54ecda4f7b365d880e39c rdf:first sg:person.01256065541.28
    366 rdf:rest N05911929ce8545c6b396ec6aa580a58d
    367 Na42b4f46e7fb4f2fa66ba8e515b287c6 rdf:first sg:person.01274547566.64
    368 rdf:rest Nf1246506c33744069c2c963ebcb6c7b6
    369 Na6ddbc30e4b4448fa94eda56e1633c2f schema:affiliation N3ec6b95a731248bf8acc9333973cf9bd
    370 schema:familyName Frühwald
    371 schema:givenName Michael C.
    372 rdf:type schema:Person
    373 Na7aa15eab6424f0c81fe10ae29eb012a rdf:first sg:person.01050265446.42
    374 rdf:rest Nc4287e8a4a3b4554a67f097d3ffd47b0
    375 Na947f71161dd41c1a787b52031273648 rdf:first sg:person.01162773425.66
    376 rdf:rest N257db6a66ee34a6f96ee70a41376a0cd
    377 Nacac795f54914efa941015c1f92a5b98 rdf:first N0d3072d66f50431899d34a367b90fc0c
    378 rdf:rest N3bebbe0988414b73bf749b6bb946d24f
    379 Nad5f7a2f0e6540978945a6f70b338c32 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    380 schema:name Central Nervous System Neoplasms
    381 rdf:type schema:DefinedTerm
    382 Nb12dda81df31405cb9a3061c4c8371a0 rdf:first sg:person.015472057034.65
    383 rdf:rest N461c6e2022a84719b1b202bf9ca169ae
    384 Nb154b002ed424c23950fe1df53ef5e11 rdf:first sg:person.01220632656.30
    385 rdf:rest N583719cb1e8841feac297e02e850891f
    386 Nb1b6bbec9ecb47f0b215bc4d4027c758 rdf:first sg:person.01125313653.25
    387 rdf:rest N4963198154c84fc0863f334b00f7771c
    388 Nb5f07e16d9d248f39c1b9bf4b7c2285e schema:name Department of Neurology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
    389 rdf:type schema:Organization
    390 Nb89ef65ba1cc4335b5cbf31b492cef7d rdf:first sg:person.0747034720.79
    391 rdf:rest N54de5b49555b4356a6ebcb1adf493e2f
    392 Nb9c6b8f48ca7460d855b52f021eed568 rdf:first sg:person.0703422661.29
    393 rdf:rest Nf4261fe4b0fb4137a791cf0ba131e4a4
    394 Nbab6f74208514f549e5076952f9b8fad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    395 schema:name Adult
    396 rdf:type schema:DefinedTerm
    397 Nbb89de7561ce4031adca4266a83f5282 rdf:first sg:person.013541325272.97
    398 rdf:rest N1ceff24e7fa94ecfa36fa205a0367d1d
    399 Nbc4506a2ea0c407f9b4f31c548e98443 schema:affiliation https://www.grid.ac/institutes/grid.410567.1
    400 schema:familyName Frank
    401 schema:givenName Stephan
    402 rdf:type schema:Person
    403 Nbc6d164972104c98bd50c75973790d34 schema:name nlm_unique_id
    404 schema:value 0410462
    405 rdf:type schema:PropertyValue
    406 Nbca888b23a194b9698e5c819e66a6549 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    407 schema:name Aged, 80 and over
    408 rdf:type schema:DefinedTerm
    409 Nbda01b23ebf54529b05ce206f4cfe9a9 rdf:first N0956b5c40f054fb58c18b4383b5bf860
    410 rdf:rest Nea572765be084b23a96003930c8f53e2
    411 Nc1119762e8f04dcb940fc1855a20edf2 rdf:first sg:person.01254147625.16
    412 rdf:rest N002281d05cd240ffa7ee6160bc1c60e6
    413 Nc22e5a34da2b4dbaaf42a74f9a2274a5 rdf:first Nf638e4f9fd4b4e00885b22b547cd66e2
    414 rdf:rest N81827f5ae26c48ff8f73157ba97596a5
    415 Nc3352c607ee4466d9c7934cfdfa452ea rdf:first sg:person.01135120445.27
    416 rdf:rest N3b576cd427b047a29e34c91a53c4b456
    417 Nc3e0d5a8be034581bae47b3a0f654a5d schema:name pubmed_id
    418 schema:value 29539639
    419 rdf:type schema:PropertyValue
    420 Nc4287e8a4a3b4554a67f097d3ffd47b0 rdf:first sg:person.01321530670.66
    421 rdf:rest N72efb3de9dd74ec9a7e8632476b26777
    422 Nc42976c607bc424c8e34cc1468629074 rdf:first sg:person.0763515656.31
    423 rdf:rest Nbb89de7561ce4031adca4266a83f5282
    424 Nc477760f39f645d49711951ad26fafea rdf:first N9722b30669c5444ba3f0490193b7fb0e
    425 rdf:rest N6a64cebd98cc4f44bd47dccd57140b4f
    426 Nc4ab707ea3eb4db1b6eed3236e201028 rdf:first sg:person.01260265434.38
    427 rdf:rest Nefaf45727a064b98b0cd4252a0556021
    428 Nc61e7f3d66a2461da60b5b5119391941 schema:name Department of Pathology, Odense University Hospital, Department of Clinical Research, University of Southern Denmark, Odense, Denmark
    429 rdf:type schema:Organization
    430 Nc6228ff1c38d4c1a9287e6f6863781f5 rdf:first sg:person.010563327577.08
    431 rdf:rest N90d7f387bea446c8ad35cac654c0c980
    432 Nc6eb610816c34b28b24ff1ca95d4273a rdf:first sg:person.01143304676.41
    433 rdf:rest Ndd3ccc7dc7e841f2b316032d86097428
    434 Nc8af48ff16d24727a57ca1330624b264 rdf:first Na28650c51f3b4e09ad2e4f5eda6e0c2c
    435 rdf:rest Na7aa15eab6424f0c81fe10ae29eb012a
    436 Nc90b15e96c2d480c83632545569ff683 rdf:first sg:person.01030642337.37
    437 rdf:rest N3a814faa31524e90a5607b625f602cb7
    438 Nc993eea4cf514895bfdac62b77a8dab8 rdf:first N271f8ed0c32b4736ad4bb7aca7ca5826
    439 rdf:rest Nffd9220b054146a89fd55d145669080e
    440 Nca68210cadc24624a775b8393e454e21 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    441 schema:name Cohort Studies
    442 rdf:type schema:DefinedTerm
    443 Ncae90faefee04f71be8667e58683cdbf rdf:first sg:person.01053310042.43
    444 rdf:rest Ndeb125e4322a409c96c24ca633f0776b
    445 Ncb602b6cf6a94737b2e9444880f5417f rdf:first sg:person.01222402317.17
    446 rdf:rest Neb84e6cc3bcc4203a3b81317bd5aa38d
    447 Ncbc8cfda301b4a8a9d3f34f1b1ec0215 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
    448 schema:familyName Hartmann
    449 schema:givenName Christian
    450 rdf:type schema:Person
    451 Ncd7ce3b0217c40fb8bcb297488610366 rdf:first sg:person.01306714315.48
    452 rdf:rest N98924501357a44d99a61db31eeceb69d
    453 Nd160c4d622d740b5a94ac87ab53daa1e rdf:first sg:person.0717255005.87
    454 rdf:rest Nc42976c607bc424c8e34cc1468629074
    455 Nd4c74e7ecd39410a942b2abcd77b11a6 rdf:first sg:person.01242715675.01
    456 rdf:rest Na42b4f46e7fb4f2fa66ba8e515b287c6
    457 Nd4dd2b2ddc894f47b7d56851d8e1b803 rdf:first sg:person.01330376505.46
    458 rdf:rest Ne95a554d03be4942b2e976dcaed87c1e
    459 Nd56e183243274b108ab69cd5ac08ed2e rdf:first sg:person.0757363774.37
    460 rdf:rest Ncd7ce3b0217c40fb8bcb297488610366
    461 Nd690195161d546c5987ae4deb42ff26b rdf:first sg:person.01130262430.09
    462 rdf:rest N85fa5d4eac73426bb15cd514c700faa7
    463 Nd72720cf42264c81a64e1f20c1209247 rdf:first sg:person.0633773522.25
    464 rdf:rest Nb1b6bbec9ecb47f0b215bc4d4027c758
    465 Nd7564b506df34b8ca463aaa4dc697e14 rdf:first sg:person.01105171247.76
    466 rdf:rest rdf:nil
    467 Ndad3c12c1a9446e8bccc24f60c2ad608 schema:affiliation https://www.grid.ac/institutes/grid.419123.c
    468 schema:familyName Mittelbronn
    469 schema:givenName Michel
    470 rdf:type schema:Person
    471 Ndc3cd9d239b3465abf741ddd9ceefd0b rdf:first sg:person.01201076245.32
    472 rdf:rest Na947f71161dd41c1a787b52031273648
    473 Ndcd9513497fd4b179961e43bfc6dccbc rdf:first sg:person.01137070015.52
    474 rdf:rest N8a6a4aa4c8c24b339db5008d48d3cbd5
    475 Ndd3ccc7dc7e841f2b316032d86097428 rdf:first sg:person.01260652230.98
    476 rdf:rest N59d8ac0165544022be3d8239b722b8e2
    477 Nddd88b33412e4d60a863c0edbf9a057a rdf:first sg:person.01361245264.52
    478 rdf:rest N57c17e0dd03b4c41b4f322fb49470f0d
    479 Nde8a438c211a4a10a9ebb8b4de331ad0 rdf:first sg:person.01312431477.50
    480 rdf:rest N8b78dcc8a3a14b1189a9bb9063511c89
    481 Ndeb125e4322a409c96c24ca633f0776b rdf:first sg:person.01243232701.95
    482 rdf:rest N41248fdc59654c2fb8871948f1b3ab39
    483 Ndebd2e61600846c89c21667afdeb7147 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    484 schema:name Young Adult
    485 rdf:type schema:DefinedTerm
    486 Ndec1b12302eb45f7a3c7b004948fd8ff schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    487 schema:familyName Fischer
    488 schema:givenName Roger
    489 rdf:type schema:Person
    490 Ndfc972de746a4bdd93667116b38ec4ff rdf:first sg:person.01342767063.25
    491 rdf:rest Nb89ef65ba1cc4335b5cbf31b492cef7d
    492 Ne1de9c2df4fe4a36877d4fd36f4b155b schema:affiliation https://www.grid.ac/institutes/grid.5718.b
    493 schema:familyName Lohmann
    494 schema:givenName Dietmar
    495 rdf:type schema:Person
    496 Ne1e61aea4e314409be7e89ded402323c schema:volumeNumber 555
    497 rdf:type schema:PublicationVolume
    498 Ne28a3ef58ceb4cb6969f56e26b7b3441 rdf:first sg:person.013420042021.61
    499 rdf:rest N817cfd556db24942868eaab7f6bf0f37
    500 Ne3b9981949d145b0b72b15e0a6bd6335 rdf:first sg:person.0657742371.33
    501 rdf:rest Nb12dda81df31405cb9a3061c4c8371a0
    502 Ne477f6d38e92472fab6f6a062fc2e29d rdf:first sg:person.01261675111.82
    503 rdf:rest N7d39e0628ba54fb8a11190e7a8abe551
    504 Ne574a92dd4654328aec0e24c94d8e7df rdf:first Ne1de9c2df4fe4a36877d4fd36f4b155b
    505 rdf:rest N8c5a41a20f7544c18b4f77450011b9ba
    506 Ne7b72eb62e24481ca3c5b732792214fa schema:name Institute for Pathology, Katharinenhospital Stuttgart, Stuttgart, Germany
    507 rdf:type schema:Organization
    508 Ne95a554d03be4942b2e976dcaed87c1e rdf:first Ncbc8cfda301b4a8a9d3f34f1b1ec0215
    509 rdf:rest N7a275641d0664d59bfa7dfdf3b9907f6
    510 Nea572765be084b23a96003930c8f53e2 rdf:first sg:person.0662562774.17
    511 rdf:rest N3561f26d6da54cdba8869bf4630515c7
    512 Neb5fee885be14326b0696c4e047de433 schema:affiliation N98a0f99658af484a919b1864b1a981f5
    513 schema:familyName Mühleisen
    514 schema:givenName Helmut
    515 rdf:type schema:Person
    516 Neb84e6cc3bcc4203a3b81317bd5aa38d rdf:first sg:person.010222631377.97
    517 rdf:rest Nc90b15e96c2d480c83632545569ff683
    518 Neb8bc1c9f02d4619976c3e533f174347 rdf:first sg:person.015657111262.11
    519 rdf:rest Nd4c74e7ecd39410a942b2abcd77b11a6
    520 Nec625cf234e04a26b4bf0d31342b3100 schema:name Springer Nature - SN SciGraph project
    521 rdf:type schema:Organization
    522 Nece22ffc7ca743aa889e893d1d1a8d43 rdf:first sg:person.0707750521.75
    523 rdf:rest Nf444213063e94deb93c86d5161a5c805
    524 Neec4726426cd4fddad39fbd8bbb73395 rdf:first sg:person.011536141544.42
    525 rdf:rest N6030cccc92c04aa6baa90bdc346c05a6
    526 Nef0ea3af3b7b43d290a970724a03c453 rdf:first N9840edad74a64420ba1f9baffebce32b
    527 rdf:rest N6c536faf290d49599b348cceab8badd8
    528 Nefaf45727a064b98b0cd4252a0556021 rdf:first sg:person.0736755752.42
    529 rdf:rest Ne3b9981949d145b0b72b15e0a6bd6335
    530 Nf04ad730bf3a4789b4260f0626ddcd30 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    531 schema:name Unsupervised Machine Learning
    532 rdf:type schema:DefinedTerm
    533 Nf1246506c33744069c2c963ebcb6c7b6 rdf:first Nbc4506a2ea0c407f9b4f31c548e98443
    534 rdf:rest Nc8af48ff16d24727a57ca1330624b264
    535 Nf250f3173e0549909979df331e77f97c rdf:first sg:person.01366560070.11
    536 rdf:rest Nc1119762e8f04dcb940fc1855a20edf2
    537 Nf25e38d05d444b21a9d4ce5422c92894 rdf:first sg:person.0767624634.57
    538 rdf:rest N66e0ac7966474116a132290d89db26e0
    539 Nf4261fe4b0fb4137a791cf0ba131e4a4 rdf:first sg:person.07524506162.54
    540 rdf:rest N347e972d840548ca8673e6f589c73c8e
    541 Nf444213063e94deb93c86d5161a5c805 rdf:first sg:person.01057011740.23
    542 rdf:rest N23d6b2cf23534703b45cd0616381c239
    543 Nf5b14fd579d44d8e95c067d96eb62500 rdf:first sg:person.01250404162.21
    544 rdf:rest N49a3e85849bd44cfb4cae8a6061a2864
    545 Nf638e4f9fd4b4e00885b22b547cd66e2 schema:affiliation https://www.grid.ac/institutes/grid.13648.38
    546 schema:familyName Rutkowski
    547 schema:givenName Stefan
    548 rdf:type schema:Person
    549 Nf78bd08978e54ec48d77d198c2212c5a rdf:first sg:person.01056344227.56
    550 rdf:rest N5b0124d3662a49a396624f2d7b2ff214
    551 Nf79544624e9d42dfa84f03b29d244664 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    552 schema:name Adolescent
    553 rdf:type schema:DefinedTerm
    554 Nf861fbb4fbb54b12bcd6e1afc4270325 rdf:first N55afc3f3863d4df3812a83accf7a5db5
    555 rdf:rest Nc6228ff1c38d4c1a9287e6f6863781f5
    556 Nf8b445fc36664d68a45a655c4b3a0434 rdf:first Ndec1b12302eb45f7a3c7b004948fd8ff
    557 rdf:rest N5b0407cb299b4ce782b99b3d09a321e7
    558 Nfaae96d647d5414890e00e6ce589b770 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    559 schema:familyName Lindenberg
    560 schema:givenName Kerstin
    561 rdf:type schema:Person
    562 Nfe6bc39366a2442a90d30c7087f9001c rdf:first sg:person.0600656007.06
    563 rdf:rest Nd160c4d622d740b5a94ac87ab53daa1e
    564 Nfec1d65a6c904b879d02792af1c53c3e schema:affiliation https://www.grid.ac/institutes/grid.266102.1
    565 schema:familyName Perry
    566 schema:givenName Arie
    567 rdf:type schema:Person
    568 Nffd9220b054146a89fd55d145669080e rdf:first N985d213d3ba04ed29ef5d9e910d717c2
    569 rdf:rest Nb9c6b8f48ca7460d855b52f021eed568
    570 Nffebadaef8714042b48af48a42cdf48e rdf:first sg:person.01153074764.27
    571 rdf:rest Nc477760f39f645d49711951ad26fafea
    572 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    573 schema:name Medical and Health Sciences
    574 rdf:type schema:DefinedTerm
    575 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
    576 schema:name Oncology and Carcinogenesis
    577 rdf:type schema:DefinedTerm
    578 sg:grant.2438793 http://pending.schema.org/fundedItem sg:pub.10.1038/nature26000
    579 rdf:type schema:MonetaryGrant
    580 sg:grant.2682838 http://pending.schema.org/fundedItem sg:pub.10.1038/nature26000
    581 rdf:type schema:MonetaryGrant
    582 sg:journal.1018957 schema:issn 0090-0028
    583 1476-4687
    584 schema:name Nature
    585 rdf:type schema:Periodical
    586 sg:person.01006163216.47 schema:affiliation https://www.grid.ac/institutes/grid.411778.c
    587 schema:familyName Seiz-Rosenhagen
    588 schema:givenName Marcel
    589 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006163216.47
    590 rdf:type schema:Person
    591 sg:person.01016616471.07 schema:affiliation https://www.grid.ac/institutes/grid.5718.b
    592 schema:familyName Hans
    593 schema:givenName Volkmar
    594 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016616471.07
    595 rdf:type schema:Person
    596 sg:person.010222631377.97 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
    597 schema:familyName Wani
    598 schema:givenName Khalida
    599 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010222631377.97
    600 rdf:type schema:Person
    601 sg:person.01022515007.00 schema:affiliation https://www.grid.ac/institutes/grid.5253.1
    602 schema:familyName Kulozik
    603 schema:givenName Andreas
    604 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022515007.00
    605 rdf:type schema:Person
    606 sg:person.01023212571.19 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    607 schema:familyName Rodriguez
    608 schema:givenName Fausto J.
    609 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023212571.19
    610 rdf:type schema:Person
    611 sg:person.01030642337.37 schema:affiliation https://www.grid.ac/institutes/grid.414435.3
    612 schema:familyName Varlet
    613 schema:givenName Pascale
    614 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030642337.37
    615 rdf:type schema:Person
    616 sg:person.01043273753.26 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    617 schema:familyName Capper
    618 schema:givenName David
    619 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043273753.26
    620 rdf:type schema:Person
    621 sg:person.01050265446.42 schema:affiliation https://www.grid.ac/institutes/grid.240324.3
    622 schema:familyName Kannan
    623 schema:givenName Kasthuri
    624 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050265446.42
    625 rdf:type schema:Person
    626 sg:person.01051416514.73 schema:affiliation https://www.grid.ac/institutes/grid.411778.c
    627 schema:familyName Hänggi
    628 schema:givenName Daniel
    629 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051416514.73
    630 rdf:type schema:Person
    631 sg:person.01051617612.15 schema:affiliation https://www.grid.ac/institutes/grid.419543.e
    632 schema:familyName Giangaspero
    633 schema:givenName Felice
    634 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051617612.15
    635 rdf:type schema:Person
    636 sg:person.01053310042.43 schema:affiliation https://www.grid.ac/institutes/grid.5253.1
    637 schema:familyName Schweizer
    638 schema:givenName Leonille
    639 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053310042.43
    640 rdf:type schema:Person
    641 sg:person.010563327577.08 schema:affiliation https://www.grid.ac/institutes/grid.240871.8
    642 schema:familyName Northcott
    643 schema:givenName Paul A.
    644 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010563327577.08
    645 rdf:type schema:Person
    646 sg:person.01056344227.56 schema:affiliation https://www.grid.ac/institutes/grid.413354.4
    647 schema:familyName Hofer
    648 schema:givenName Silvia
    649 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056344227.56
    650 rdf:type schema:Person
    651 sg:person.01057011740.23 schema:affiliation https://www.grid.ac/institutes/grid.424537.3
    652 schema:familyName Jacques
    653 schema:givenName Thomas S.
    654 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057011740.23
    655 rdf:type schema:Person
    656 sg:person.01061264270.01 schema:affiliation https://www.grid.ac/institutes/grid.410718.b
    657 schema:familyName Tippelt
    658 schema:givenName Stephan
    659 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061264270.01
    660 rdf:type schema:Person
    661 sg:person.01064137712.31 schema:affiliation https://www.grid.ac/institutes/grid.410718.b
    662 schema:familyName Temming
    663 schema:givenName Petra
    664 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064137712.31
    665 rdf:type schema:Person
    666 sg:person.01074367672.42 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    667 schema:familyName Reuss
    668 schema:givenName David E.
    669 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074367672.42
    670 rdf:type schema:Person
    671 sg:person.01104073627.88 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    672 schema:familyName Sill
    673 schema:givenName Martin
    674 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104073627.88
    675 rdf:type schema:Person
    676 sg:person.01105171247.76 schema:affiliation https://www.grid.ac/institutes/grid.5253.1
    677 schema:familyName Pfister
    678 schema:givenName Stefan M.
    679 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105171247.76
    680 rdf:type schema:Person
    681 sg:person.01124352515.36 schema:affiliation https://www.grid.ac/institutes/grid.5253.1
    682 schema:familyName Sturm
    683 schema:givenName Dominik
    684 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124352515.36
    685 rdf:type schema:Person
    686 sg:person.01125313653.25 schema:affiliation https://www.grid.ac/institutes/grid.451012.3
    687 schema:familyName Bjerkvig
    688 schema:givenName Rolf
    689 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125313653.25
    690 rdf:type schema:Person
    691 sg:person.01126205153.63 schema:affiliation https://www.grid.ac/institutes/grid.5560.6
    692 schema:familyName Müller
    693 schema:givenName Hermann L.
    694 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126205153.63
    695 rdf:type schema:Person
    696 sg:person.01130262430.09 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    697 schema:familyName Bewerunge-Hudler
    698 schema:givenName Melanie
    699 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130262430.09
    700 rdf:type schema:Person
    701 sg:person.011341621677.42 schema:affiliation https://www.grid.ac/institutes/grid.5253.1
    702 schema:familyName Unterberg
    703 schema:givenName Andreas
    704 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011341621677.42
    705 rdf:type schema:Person
    706 sg:person.01134175470.77 schema:affiliation https://www.grid.ac/institutes/grid.414315.6
    707 schema:familyName Cryan
    708 schema:givenName Jane
    709 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134175470.77
    710 rdf:type schema:Person
    711 sg:person.01135120445.27 schema:affiliation https://www.grid.ac/institutes/grid.5253.1
    712 schema:familyName Wick
    713 schema:givenName Wolfgang
    714 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01135120445.27
    715 rdf:type schema:Person
    716 sg:person.01137070015.52 schema:affiliation https://www.grid.ac/institutes/grid.16149.3b
    717 schema:familyName Hasselblatt
    718 schema:givenName Martin
    719 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137070015.52
    720 rdf:type schema:Person
    721 sg:person.01143304676.41 schema:affiliation https://www.grid.ac/institutes/grid.5807.a
    722 schema:familyName Mawrin
    723 schema:givenName Christian
    724 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143304676.41
    725 rdf:type schema:Person
    726 sg:person.01153074764.27 schema:affiliation https://www.grid.ac/institutes/grid.484013.a
    727 schema:familyName Heppner
    728 schema:givenName Frank
    729 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153074764.27
    730 rdf:type schema:Person
    731 sg:person.01153246175.48 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    732 schema:familyName Koelsche
    733 schema:givenName Christian
    734 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153246175.48
    735 rdf:type schema:Person
    736 sg:person.011536141544.42 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    737 schema:familyName Jones
    738 schema:givenName David T. W.
    739 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011536141544.42
    740 rdf:type schema:Person
    741 sg:person.01161510677.60 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    742 schema:familyName Karajannis
    743 schema:givenName Matthias A.
    744 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161510677.60
    745 rdf:type schema:Person
    746 sg:person.01162773425.66 schema:affiliation https://www.grid.ac/institutes/grid.411984.1
    747 schema:familyName Kramm
    748 schema:givenName Christof M.
    749 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162773425.66
    750 rdf:type schema:Person
    751 sg:person.01175561336.61 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    752 schema:familyName Schick
    753 schema:givenName Matthias
    754 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175561336.61
    755 rdf:type schema:Person
    756 sg:person.01201076245.32 schema:affiliation https://www.grid.ac/institutes/grid.6363.0
    757 schema:familyName Driever
    758 schema:givenName Pablo Hernáiz
    759 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201076245.32
    760 rdf:type schema:Person
    761 sg:person.01206710443.02 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    762 schema:familyName Kool
    763 schema:givenName Marcel
    764 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206710443.02
    765 rdf:type schema:Person
    766 sg:person.01207421574.89 schema:affiliation Nb5f07e16d9d248f39c1b9bf4b7c2285e
    767 schema:familyName Platten
    768 schema:givenName Michael
    769 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207421574.89
    770 rdf:type schema:Person
    771 sg:person.01220310166.56 schema:affiliation https://www.grid.ac/institutes/grid.240324.3
    772 schema:familyName Snuderl
    773 schema:givenName Matija
    774 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220310166.56
    775 rdf:type schema:Person
    776 sg:person.01220632656.30 schema:affiliation https://www.grid.ac/institutes/grid.418542.e
    777 schema:familyName Ryzhova
    778 schema:givenName Marina
    779 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01220632656.30
    780 rdf:type schema:Person
    781 sg:person.01222402317.17 schema:affiliation N0d163d46111a41beaf66e6a4b2e014a1
    782 schema:familyName Staszewski
    783 schema:givenName Ori
    784 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222402317.17
    785 rdf:type schema:Person
    786 sg:person.01226707144.32 schema:affiliation https://www.grid.ac/institutes/grid.411778.c
    787 schema:familyName Brehmer
    788 schema:givenName Stefanie
    789 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226707144.32
    790 rdf:type schema:Person
    791 sg:person.01234464637.55 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    792 schema:familyName Schrimpf
    793 schema:givenName Daniel
    794 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234464637.55
    795 rdf:type schema:Person
    796 sg:person.01235252033.21 schema:affiliation https://www.grid.ac/institutes/grid.8664.c
    797 schema:familyName Garvalov
    798 schema:givenName Boyan K.
    799 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235252033.21
    800 rdf:type schema:Person
    801 sg:person.01242105220.02 schema:affiliation https://www.grid.ac/institutes/grid.240871.8
    802 schema:familyName Robinson
    803 schema:givenName Giles W.
    804 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242105220.02
    805 rdf:type schema:Person
    806 sg:person.01242715675.01 schema:affiliation https://www.grid.ac/institutes/grid.411097.a
    807 schema:familyName Deckert
    808 schema:givenName Martina
    809 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242715675.01
    810 rdf:type schema:Person
    811 sg:person.01243232701.95 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    812 schema:familyName Stichel
    813 schema:givenName Damian
    814 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243232701.95
    815 rdf:type schema:Person
    816 sg:person.01243467607.83 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    817 schema:familyName Lichter
    818 schema:givenName Peter
    819 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243467607.83
    820 rdf:type schema:Person
    821 sg:person.01247463220.45 schema:affiliation https://www.grid.ac/institutes/grid.22937.3d
    822 schema:familyName Preusser
    823 schema:givenName Matthias
    824 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247463220.45
    825 rdf:type schema:Person
    826 sg:person.01250404162.21 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    827 schema:familyName Chavez
    828 schema:givenName Lukas
    829 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250404162.21
    830 rdf:type schema:Person
    831 sg:person.01252521363.91 schema:affiliation https://www.grid.ac/institutes/grid.16872.3a
    832 schema:familyName Wesseling
    833 schema:givenName Pieter
    834 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252521363.91
    835 rdf:type schema:Person
    836 sg:person.01254147625.16 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    837 schema:familyName Zapatka
    838 schema:givenName Marc
    839 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01254147625.16
    840 rdf:type schema:Person
    841 sg:person.01255521146.21 schema:affiliation https://www.grid.ac/institutes/grid.83440.3b
    842 schema:familyName Brandner
    843 schema:givenName Sebastian
    844 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255521146.21
    845 rdf:type schema:Person
    846 sg:person.01256065541.28 schema:affiliation https://www.grid.ac/institutes/grid.10388.32
    847 schema:familyName Gessi
    848 schema:givenName Marco
    849 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256065541.28
    850 rdf:type schema:Person
    851 sg:person.01257065704.47 schema:affiliation https://www.grid.ac/institutes/grid.415486.a
    852 schema:familyName Khatib
    853 schema:givenName Ziad
    854 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257065704.47
    855 rdf:type schema:Person
    856 sg:person.01260265434.38 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    857 schema:familyName Harter
    858 schema:givenName Patrick N.
    859 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260265434.38
    860 rdf:type schema:Person
    861 sg:person.01260652230.98 schema:affiliation https://www.grid.ac/institutes/grid.411937.9
    862 schema:familyName Ketter
    863 schema:givenName Ralf
    864 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260652230.98
    865 rdf:type schema:Person
    866 sg:person.01261675111.82 schema:affiliation https://www.grid.ac/institutes/grid.419927.0
    867 schema:familyName Geisenberger
    868 schema:givenName Christoph
    869 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261675111.82
    870 rdf:type schema:Person
    871 sg:person.012731463207.92 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
    872 schema:familyName Taylor
    873 schema:givenName Michael D.
    874 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012731463207.92
    875 rdf:type schema:Person
    876 sg:person.01274547566.64 schema:affiliation https://www.grid.ac/institutes/grid.410567.1
    877 schema:familyName Hench
    878 schema:givenName Jürgen
    879 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274547566.64
    880 rdf:type schema:Person
    881 sg:person.01276006465.63 schema:affiliation https://www.grid.ac/institutes/grid.1008.9
    882 schema:familyName Hansford
    883 schema:givenName Jordan R.
    884 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276006465.63
    885 rdf:type schema:Person
    886 sg:person.01306714315.48 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
    887 schema:familyName Milde
    888 schema:givenName Till
    889 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306714315.48
    890 rdf:type schema:Person
    891 sg:person.01312431477.50 schema:affiliation https://www.grid.ac/institutes/grid.10388.32
    892 schema:familyName Becker
    893 schema:givenName Albert
    894 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312431477.50
    895