DNA methylation-based classification of central nervous system tumours View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-03

AUTHORS

David Capper, David T. W. Jones, Martin Sill, Volker Hovestadt, Daniel Schrimpf, Dominik Sturm, Christian Koelsche, Felix Sahm, Lukas Chavez, David E. Reuss, Annekathrin Kratz, Annika K. Wefers, Kristin Huang, Kristian W. Pajtler, Leonille Schweizer, Damian Stichel, Adriana Olar, Nils W. Engel, Kerstin Lindenberg, Patrick N. Harter, Anne K. Braczynski, Karl H. Plate, Hildegard Dohmen, Boyan K. Garvalov, Roland Coras, Annett Hölsken, Ekkehard Hewer, Melanie Bewerunge-Hudler, Matthias Schick, Roger Fischer, Rudi Beschorner, Jens Schittenhelm, Ori Staszewski, Khalida Wani, Pascale Varlet, Melanie Pages, Petra Temming, Dietmar Lohmann, Florian Selt, Hendrik Witt, Till Milde, Olaf Witt, Eleonora Aronica, Felice Giangaspero, Elisabeth Rushing, Wolfram Scheurlen, Christoph Geisenberger, Fausto J. Rodriguez, Albert Becker, Matthias Preusser, Christine Haberler, Rolf Bjerkvig, Jane Cryan, Michael Farrell, Martina Deckert, Jürgen Hench, Stephan Frank, Jonathan Serrano, Kasthuri Kannan, Aristotelis Tsirigos, Wolfgang Brück, Silvia Hofer, Stefanie Brehmer, Marcel Seiz-Rosenhagen, Daniel Hänggi, Volkmar Hans, Stephanie Rozsnoki, Jordan R. Hansford, Patricia Kohlhof, Bjarne W. Kristensen, Matt Lechner, Beatriz Lopes, Christian Mawrin, Ralf Ketter, Andreas Kulozik, Ziad Khatib, Frank Heppner, Arend Koch, Anne Jouvet, Catherine Keohane, Helmut Mühleisen, Wolf Mueller, Ute Pohl, Marco Prinz, Axel Benner, Marc Zapatka, Nicholas G. Gottardo, Pablo Hernáiz Driever, Christof M. Kramm, Hermann L. Müller, Stefan Rutkowski, Katja von Hoff, Michael C. Frühwald, Astrid Gnekow, Gudrun Fleischhack, Stephan Tippelt, Gabriele Calaminus, Camelia-Maria Monoranu, Arie Perry, Chris Jones, Thomas S. Jacques, Bernhard Radlwimmer, Marco Gessi, Torsten Pietsch, Johannes Schramm, Gabriele Schackert, Manfred Westphal, Guido Reifenberger, Pieter Wesseling, Michael Weller, Vincent Peter Collins, Ingmar Blümcke, Martin Bendszus, Jürgen Debus, Annie Huang, Nada Jabado, Paul A. Northcott, Werner Paulus, Amar Gajjar, Giles W. Robinson, Michael D. Taylor, Zane Jaunmuktane, Marina Ryzhova, Michael Platten, Andreas Unterberg, Wolfgang Wick, Matthias A. Karajannis, Michel Mittelbronn, Till Acker, Christian Hartmann, Kenneth Aldape, Ulrich Schüller, Rolf Buslei, Peter Lichter, Marcel Kool, Christel Herold-Mende, David W. Ellison, Martin Hasselblatt, Matija Snuderl, Sebastian Brandner, Andrey Korshunov, Andreas von Deimling, Stefan M. Pfister

ABSTRACT

Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-with substantial inter-observer variability in the histopathological diagnosis of many tumour types. Here we present a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and demonstrate its application in a routine diagnostic setting. We show that the availability of this method may have a substantial impact on diagnostic precision compared to standard methods, resulting in a change of diagnosis in up to 12% of prospective cases. For broader accessibility, we have designed a free online classifier tool, the use of which does not require any additional onsite data processing. Our results provide a blueprint for the generation of machine-learning-based tumour classifiers across other cancer entities, with the potential to fundamentally transform tumour pathology. More... »

PAGES

469

References to SciGraph publications

  • 2011-12. Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts in JOURNAL OF NEGATIVE RESULTS IN BIOMEDICINE
  • 2013-08. Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma in ACTA NEUROPATHOLOGICA
  • 2016-12. Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles in ACTA NEUROPATHOLOGICA COMMUNICATIONS
  • 2013-06. Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays in ACTA NEUROPATHOLOGICA
  • 2015-05. Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups in ACTA NEUROPATHOLOGICA
  • 2001-11. A Simple Generalisation of the Area Under the ROC Curve for Multiple Class Classification Problems in MACHINE LEARNING
  • 2015-02. Orchestrating high-throughput genomic analysis with Bioconductor in NATURE METHODS
  • 2014-10. Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma in ACTA NEUROPATHOLOGICA
  • 2014-06. Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing in NATURE
  • 2014-02. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy in NATURE
  • 2013-08. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma in NATURE GENETICS
  • 2014-07. Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort in ACTA NEUROPATHOLOGICA
  • 2012-08. Dissecting the genomic complexity underlying medulloblastoma in NATURE
  • 2012-05. Absolute quantification of somatic DNA alterations in human cancer in NATURE BIOTECHNOLOGY
  • 2016-06. Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets in ACTA NEUROPATHOLOGICA
  • 2014-08. Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity in ACTA NEUROPATHOLOGICA
  • 2016-01. Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity in ACTA NEUROPATHOLOGICA
  • 2001-10. Random Forests in MACHINE LEARNING
  • 2015-09. Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities in ACTA NEUROPATHOLOGICA
  • 2010-09. Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician’s perspective in ACTA NEUROPATHOLOGICA
  • 2012-01. Reinventing clinical trials in NATURE BIOTECHNOLOGY
  • Journal

    TITLE

    Nature

    ISSUE

    7697

    VOLUME

    555

    Author Affiliations

  • German Cancer Research Center
  • University Hospital Heidelberg
  • Hollings Cancer Center
  • Ludwig Maximilian University of Munich
  • University of Giessen
  • University of Bern
  • Universitätsklinikum Tübingen
  • The University of Texas MD Anderson Cancer Center
  • Centre Hospitalier Sainte-Anne
  • Essen University Hospital
  • University of Duisburg-Essen
  • Stichting Epilepsie Instellingen Nederland
  • Istituto Neurologico Mediterraneo
  • University Hospital of Zurich
  • Cnopf´sche Kinderklinik
  • Hubrecht Institute
  • Johns Hopkins University
  • University of Bonn
  • Medical University of Vienna
  • Luxembourg Institute of Health
  • Beaumont Hospital
  • University Hospital Cologne
  • University Hospital of Basel
  • New York University Langone Medical Center
  • Universitätsmedizin Göttingen
  • Luzerner Kantonsspital
  • University Medical Centre Mannheim
  • University Hospital Münster
  • University of Melbourne
  • University College London
  • University of Virginia
  • Otto-von-Guericke University Magdeburg
  • Universitätsklinikum des Saarlandes
  • Miami Children's Hospital
  • Berlin Institute of Health
  • Hôpital Pierre Wertheimer
  • Cork University Hospital
  • Leipzig University
  • Queen's Hospital
  • University of Freiburg
  • University of Western Australia
  • Charité
  • Carl von Ossietzky University of Oldenburg
  • University Medical Center Hamburg-Eppendorf
  • University Hospital Bonn
  • University of Würzburg
  • University of California, San Francisco
  • Institute of Cancer Research
  • Great Ormond Street Hospital for Children NHS Foundation Trust
  • VU University Medical Center
  • University of Zurich
  • University of Cambridge
  • University of Toronto
  • McGill University
  • St. Jude Children's Research Hospital
  • Burdenko Neurosurgery Institute
  • Memorial Sloan Kettering Cancer Center
  • Laboratoire National de Santé
  • Hannover Medical School
  • Sozialstiftung Bamberg
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature26000

    DOI

    http://dx.doi.org/10.1038/nature26000

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1101533700

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29539639


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