The axolotl genome and the evolution of key tissue formation regulators View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-02

AUTHORS

Sergej Nowoshilow, Siegfried Schloissnig, Ji-Feng Fei, Andreas Dahl, Andy W. C. Pang, Martin Pippel, Sylke Winkler, Alex R. Hastie, George Young, Juliana G. Roscito, Francisco Falcon, Dunja Knapp, Sean Powell, Alfredo Cruz, Han Cao, Bianca Habermann, Michael Hiller, Elly M. Tanaka, Eugene W. Myers

ABSTRACT

Salamanders serve as important tetrapod models for developmental, regeneration and evolutionary studies. An extensive molecular toolkit makes the Mexican axolotl (Ambystoma mexicanum) a key representative salamander for molecular investigations. Here we report the sequencing and assembly of the 32-gigabase-pair axolotl genome using an approach that combined long-read sequencing, optical mapping and development of a new genome assembler (MARVEL). We observed a size expansion of introns and intergenic regions, largely attributable to multiplication of long terminal repeat retroelements. We provide evidence that intron size in developmental genes is under constraint and that species-restricted genes may contribute to limb regeneration. The axolotl genome assembly does not contain the essential developmental gene Pax3. However, mutation of the axolotl Pax3 paralogue Pax7 resulted in an axolotl phenotype that was similar to those seen in Pax3-/- and Pax7-/- mutant mice. The axolotl genome provides a rich biological resource for developmental and evolutionary studies. More... »

PAGES

50

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature25458

DOI

http://dx.doi.org/10.1038/nature25458

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1100587495

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29364872


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ambystoma mexicanum", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Intergenic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Evolution, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Essential", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genomics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Homeodomain Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Introns", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "PAX3 Transcription Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "PAX7 Transcription Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Picea", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pinus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Regeneration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retroelements", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Terminal Repeat Sequences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany", 
            "Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.", 
            "DFG Research Center for Regenerative Therapies, Technische Universit\u00e4t Dresden, Dresden, Germany."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nowoshilow", 
        "givenName": "Sergej", 
        "id": "sg:person.01362467417.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362467417.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg Institute for Theoretical Studies", 
          "id": "https://www.grid.ac/institutes/grid.424699.4", 
          "name": [
            "Heidelberg Institute for Theoretical Studies, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schloissnig", 
        "givenName": "Siegfried", 
        "id": "sg:person.01227245513.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227245513.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "South China Normal University", 
          "id": "https://www.grid.ac/institutes/grid.263785.d", 
          "name": [
            "Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fei", 
        "givenName": "Ji-Feng", 
        "id": "sg:person.01313562662.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313562662.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "DFG Research Center for Regenerative Therapies, Technische Universit\u00e4t Dresden, Dresden, Germany.", 
            "Deep Sequencing Group, Biotechnology Center (Biotec) Technische Universit\u00e4t Dresden, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dahl", 
        "givenName": "Andreas", 
        "id": "sg:person.0724307434.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724307434.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "BioNano Genomics (United States)", 
          "id": "https://www.grid.ac/institutes/grid.470262.5", 
          "name": [
            "Bionano Genomics, San Diego, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pang", 
        "givenName": "Andy W. C.", 
        "id": "sg:person.0602025320.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602025320.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg Institute for Theoretical Studies", 
          "id": "https://www.grid.ac/institutes/grid.424699.4", 
          "name": [
            "Heidelberg Institute for Theoretical Studies, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pippel", 
        "givenName": "Martin", 
        "id": "sg:person.014427423617.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014427423617.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Max Planck Institute of Molecular Cell Biology and Genetics", 
          "id": "https://www.grid.ac/institutes/grid.419537.d", 
          "name": [
            "Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Winkler", 
        "givenName": "Sylke", 
        "id": "sg:person.0703367253.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0703367253.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "BioNano Genomics (United States)", 
          "id": "https://www.grid.ac/institutes/grid.470262.5", 
          "name": [
            "Bionano Genomics, San Diego, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hastie", 
        "givenName": "Alex R.", 
        "id": "sg:person.01265276040.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265276040.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "The Francis Crick Institute, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Young", 
        "givenName": "George", 
        "id": "sg:person.01026214557.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026214557.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Max Planck Institute for the Physics of Complex Systems", 
          "id": "https://www.grid.ac/institutes/grid.419560.f", 
          "name": [
            "Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany", 
            "Max Planck Institute for the Physics of Complex Systems, Dresden, Germany", 
            "Center for Systems Biology, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roscito", 
        "givenName": "Juliana G.", 
        "id": "sg:person.01104135401.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104135401.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Molecular and Developmental Complexity Group, Unidad de Gen\u00f3mica Avanzada, Langebio-Cinvestav, Irapuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Falcon", 
        "givenName": "Francisco", 
        "id": "sg:person.07571072610.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07571072610.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "DFG Research Center for Regenerative Therapies, Technische Universit\u00e4t Dresden, Dresden, Germany."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Knapp", 
        "givenName": "Dunja", 
        "id": "sg:person.01257413227.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257413227.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heidelberg Institute for Theoretical Studies", 
          "id": "https://www.grid.ac/institutes/grid.424699.4", 
          "name": [
            "Heidelberg Institute for Theoretical Studies, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Powell", 
        "givenName": "Sean", 
        "id": "sg:person.01252002107.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252002107.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Molecular and Developmental Complexity Group, Unidad de Gen\u00f3mica Avanzada, Langebio-Cinvestav, Irapuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cruz", 
        "givenName": "Alfredo", 
        "id": "sg:person.011232147010.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011232147010.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "BioNano Genomics (United States)", 
          "id": "https://www.grid.ac/institutes/grid.470262.5", 
          "name": [
            "Bionano Genomics, San Diego, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cao", 
        "givenName": "Han", 
        "id": "sg:person.01040462140.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040462140.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aix-Marseille University", 
          "id": "https://www.grid.ac/institutes/grid.5399.6", 
          "name": [
            "IBDM \u2013 Institut de Biologie du D\u00e9veloppement de Marseille, CNRS & Aix-Marseille Universit\u00e9, Marseille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Habermann", 
        "givenName": "Bianca", 
        "id": "sg:person.01066232042.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066232042.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Max Planck Institute for the Physics of Complex Systems", 
          "id": "https://www.grid.ac/institutes/grid.419560.f", 
          "name": [
            "Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany", 
            "Max Planck Institute for the Physics of Complex Systems, Dresden, Germany", 
            "Center for Systems Biology, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hiller", 
        "givenName": "Michael", 
        "id": "sg:person.0624077563.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624077563.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany", 
            "Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.", 
            "DFG Research Center for Regenerative Therapies, Technische Universit\u00e4t Dresden, Dresden, Germany."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tanaka", 
        "givenName": "Elly M.", 
        "id": "sg:person.01021663747.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021663747.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Max Planck Institute of Molecular Cell Biology and Genetics", 
          "id": "https://www.grid.ac/institutes/grid.419537.d", 
          "name": [
            "Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany", 
            "Center for Systems Biology, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Myers", 
        "givenName": "Eugene W.", 
        "id": "sg:person.0761445171.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761445171.42"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1046/j.1524-475x.1996.40113.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000488354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gbe/evr139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001643244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/375791a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002863166", 
          "https://doi.org/10.1038/375791a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ydbio.2009.12.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003640340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1479-7364-7-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004498076", 
          "https://doi.org/10.1186/1479-7364-7-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1241796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008853694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0955-0674(96)80087-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013024036"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btm071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014996474"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.devcel.2016.10.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016891004"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkq1061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017494830"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.301004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018737796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.200508001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019190533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep16413", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021432877", 
          "https://doi.org/10.1038/srep16413"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1534-5807(02)00288-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022443446"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1098119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022514256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1091/mbc.e15-12-0821", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024483156"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02108133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026184918", 
          "https://doi.org/10.1007/bf02108133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02108133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026184918", 
          "https://doi.org/10.1007/bf02108133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1501764112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026574330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0157106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028179677"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gbe/evu135", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028602770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2164-10-19", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028955530", 
          "https://doi.org/10.1186/1471-2164-10-19"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gbe/evu143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029894232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2016.05.038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030642172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tibtech.2013.04.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031527623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jez.1401270206", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033475744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jez.1401270206", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033475744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0061352", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034815022"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pcbi.1002936", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035247495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/dev.00975", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036952394"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.celrep.2016.12.063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038046115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/icb/icq022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038120000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ydbio.2010.05.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038426842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ydbio.2016.05.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039084029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/tpj.12886", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040889679"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jez.1400920303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047991249"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jez.1400920303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047991249"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms9684", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049186159", 
          "https://doi.org/10.1038/ncomms9684"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature16974", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053579355", 
          "https://doi.org/10.1038/nature16974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/pdb.emo128", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060408935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082886294", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gigascience/giw018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084184782"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-02", 
    "datePublishedReg": "2018-02-01", 
    "description": "Salamanders serve as important tetrapod models for developmental, regeneration and evolutionary studies. An extensive molecular toolkit makes the Mexican axolotl (Ambystoma mexicanum) a key representative salamander for molecular investigations. Here we report the sequencing and assembly of the 32-gigabase-pair axolotl genome using an approach that combined long-read sequencing, optical mapping and development of a new genome assembler (MARVEL). We observed a size expansion of introns and intergenic regions, largely attributable to multiplication of long terminal repeat retroelements. We provide evidence that intron size in developmental genes is under constraint and that species-restricted genes may contribute to limb regeneration. The axolotl genome assembly does not contain the essential developmental gene Pax3. However, mutation of the axolotl Pax3 paralogue Pax7 resulted in an axolotl phenotype that was similar to those seen in Pax3-/- and Pax7-/- mutant mice. The axolotl genome provides a rich biological resource for developmental and evolutionary studies.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nature25458", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5139536", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6798223", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7690", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "554"
      }
    ], 
    "name": "The axolotl genome and the evolution of key tissue formation regulators", 
    "pagination": "50", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "3764bbecc4f26991007592d2eb799bf86d8a7e0a668c1feddc9474b871ff62a6"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29364872"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature25458"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1100587495"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature25458", 
      "https://app.dimensions.ai/details/publication/pub.1100587495"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:26", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87109_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/nature25458"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature25458'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature25458'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature25458'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature25458'


 

This table displays all metadata directly associated to this object as RDF triples.

425 TRIPLES      21 PREDICATES      86 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature25458 schema:about N1e6ba2e9f75a4e7c90856337f07d8909
2 N3e2c42c150c3488c823d2d4958c0bcbc
3 N40d520c439954a8eab52975004875d9e
4 N55924be77e1e411596729f471b5327b3
5 N59432af9e2744f9db8546935c00039af
6 N5fde250837544a7a85056ef76edd674d
7 N68da4fdfca524af689c883ac4b752b46
8 N7a95f980c8794d0fbd2919b766c23705
9 N9874ce057ca94137b36fce384f18810b
10 N9e56b731fa8a4c7f869c4f8f13903f04
11 N9fec3127cf7c4fc78dd8a026f8fdd3af
12 Na56ce4d26d274d3a92b99ba1d130ea80
13 Nc017b1ec73a14f14845b9eb6b6812643
14 Nc91ed3990e754fcda2acf4f788e0e43c
15 Nd78f90161ae548c8b14725b3ed48ce75
16 Ndbd1fc92df25429b80dd79daa29ecd4b
17 Nde3a8dc4fe4b49368bd404c4fa969777
18 Ne812aa65f2224626a3f814658dc8b7be
19 anzsrc-for:06
20 anzsrc-for:0604
21 schema:author N998c67ddfecd4ec5809867b892d761a6
22 schema:citation sg:pub.10.1007/bf02108133
23 sg:pub.10.1038/375791a0
24 sg:pub.10.1038/nature16974
25 sg:pub.10.1038/ncomms9684
26 sg:pub.10.1038/srep16413
27 sg:pub.10.1186/1471-2164-10-19
28 sg:pub.10.1186/1479-7364-7-9
29 https://app.dimensions.ai/details/publication/pub.1082886294
30 https://doi.org/10.1002/jez.1400920303
31 https://doi.org/10.1002/jez.1401270206
32 https://doi.org/10.1016/j.cell.2016.05.038
33 https://doi.org/10.1016/j.celrep.2016.12.063
34 https://doi.org/10.1016/j.devcel.2016.10.013
35 https://doi.org/10.1016/j.tibtech.2013.04.004
36 https://doi.org/10.1016/j.ydbio.2009.12.030
37 https://doi.org/10.1016/j.ydbio.2010.05.007
38 https://doi.org/10.1016/j.ydbio.2016.05.024
39 https://doi.org/10.1016/s0955-0674(96)80087-1
40 https://doi.org/10.1016/s1534-5807(02)00288-5
41 https://doi.org/10.1046/j.1524-475x.1996.40113.x
42 https://doi.org/10.1073/pnas.1501764112
43 https://doi.org/10.1083/jcb.200508001
44 https://doi.org/10.1091/mbc.e15-12-0821
45 https://doi.org/10.1093/bioinformatics/btm071
46 https://doi.org/10.1093/gbe/evr139
47 https://doi.org/10.1093/gbe/evu135
48 https://doi.org/10.1093/gbe/evu143
49 https://doi.org/10.1093/gigascience/giw018
50 https://doi.org/10.1093/icb/icq022
51 https://doi.org/10.1093/nar/gkq1061
52 https://doi.org/10.1101/gad.301004
53 https://doi.org/10.1101/pdb.emo128
54 https://doi.org/10.1111/tpj.12886
55 https://doi.org/10.1126/science.1098119
56 https://doi.org/10.1126/science.1241796
57 https://doi.org/10.1242/dev.00975
58 https://doi.org/10.1371/journal.pcbi.1002936
59 https://doi.org/10.1371/journal.pone.0061352
60 https://doi.org/10.1371/journal.pone.0157106
61 schema:datePublished 2018-02
62 schema:datePublishedReg 2018-02-01
63 schema:description Salamanders serve as important tetrapod models for developmental, regeneration and evolutionary studies. An extensive molecular toolkit makes the Mexican axolotl (Ambystoma mexicanum) a key representative salamander for molecular investigations. Here we report the sequencing and assembly of the 32-gigabase-pair axolotl genome using an approach that combined long-read sequencing, optical mapping and development of a new genome assembler (MARVEL). We observed a size expansion of introns and intergenic regions, largely attributable to multiplication of long terminal repeat retroelements. We provide evidence that intron size in developmental genes is under constraint and that species-restricted genes may contribute to limb regeneration. The axolotl genome assembly does not contain the essential developmental gene Pax3. However, mutation of the axolotl Pax3 paralogue Pax7 resulted in an axolotl phenotype that was similar to those seen in Pax3<sup>-/-</sup> and Pax7<sup>-/-</sup> mutant mice. The axolotl genome provides a rich biological resource for developmental and evolutionary studies.
64 schema:genre research_article
65 schema:inLanguage en
66 schema:isAccessibleForFree true
67 schema:isPartOf N60ea3bac70bf4066acf973632c0070ec
68 N7651fd3552534b9093c0ced5dd3e28a4
69 sg:journal.1018957
70 schema:name The axolotl genome and the evolution of key tissue formation regulators
71 schema:pagination 50
72 schema:productId N026e4bfe110649129f51d58728f4a563
73 Na3388bad5fa74af7b7aab456e3dfbc8a
74 Nb141b142216d4e0e8090b208058252f0
75 Nbc2d5ea2b33b4de6af6b873ff4f9b6a8
76 Ncf67d38ee6564ee9ad0b86790f8bedbe
77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100587495
78 https://doi.org/10.1038/nature25458
79 schema:sdDatePublished 2019-04-11T12:26
80 schema:sdLicense https://scigraph.springernature.com/explorer/license/
81 schema:sdPublisher N8ced57c1489b4c5ea979430024387772
82 schema:url https://www.nature.com/articles/nature25458
83 sgo:license sg:explorer/license/
84 sgo:sdDataset articles
85 rdf:type schema:ScholarlyArticle
86 N026e4bfe110649129f51d58728f4a563 schema:name nlm_unique_id
87 schema:value 0410462
88 rdf:type schema:PropertyValue
89 N0d7cfcb350b540bdafdfaf83ef9d0072 rdf:first sg:person.01257413227.51
90 rdf:rest N893ad31c93bc4a8d99e57b02f82a75dc
91 N17dc31ad734147e9bd5557249f29c6f6 rdf:first sg:person.0602025320.59
92 rdf:rest N635629b8e50e4b63ae03313a516274ad
93 N1a3c96e84ef847049d1ec9cb3c3aa316 rdf:first sg:person.01040462140.83
94 rdf:rest Ne55c97b1d7ae434abea3b7a207a77692
95 N1bdd02f243f048caa49396a6d6fd78e2 rdf:first sg:person.01104135401.27
96 rdf:rest Ne8fcaf398c524033b48b525e546ee829
97 N1e6ba2e9f75a4e7c90856337f07d8909 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Retroelements
99 rdf:type schema:DefinedTerm
100 N3706e6adb1354a64a416919844522816 schema:name Molecular and Developmental Complexity Group, Unidad de Genómica Avanzada, Langebio-Cinvestav, Irapuato, Mexico
101 rdf:type schema:Organization
102 N38eda68d2db94309a7daac6101d255c9 rdf:first sg:person.0703367253.71
103 rdf:rest N4dc83e554f254a9d81c27ea48a164e62
104 N3e2c42c150c3488c823d2d4958c0bcbc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name PAX3 Transcription Factor
106 rdf:type schema:DefinedTerm
107 N3f62d37dda7d469c9fd1a237a3ee71e1 rdf:first sg:person.0761445171.42
108 rdf:rest rdf:nil
109 N40d520c439954a8eab52975004875d9e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name PAX7 Transcription Factor
111 rdf:type schema:DefinedTerm
112 N47c0ee4f4806460099d3d167f88eeaf6 rdf:first sg:person.0624077563.24
113 rdf:rest Ne3a787a4ebba42f8a432492b52be1f29
114 N4d4fd7f9dc654f8c980428b8c6750536 rdf:first sg:person.01227245513.51
115 rdf:rest Na35e5c8f40a347589c4bc497c9c2b4b0
116 N4dc83e554f254a9d81c27ea48a164e62 rdf:first sg:person.01265276040.11
117 rdf:rest N611dc9850e4147e29b2d9c55f1880422
118 N55924be77e1e411596729f471b5327b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Genes, Essential
120 rdf:type schema:DefinedTerm
121 N59432af9e2744f9db8546935c00039af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Introns
123 rdf:type schema:DefinedTerm
124 N5fde250837544a7a85056ef76edd674d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Evolution, Molecular
126 rdf:type schema:DefinedTerm
127 N60ea3bac70bf4066acf973632c0070ec schema:volumeNumber 554
128 rdf:type schema:PublicationVolume
129 N611dc9850e4147e29b2d9c55f1880422 rdf:first sg:person.01026214557.58
130 rdf:rest N1bdd02f243f048caa49396a6d6fd78e2
131 N635629b8e50e4b63ae03313a516274ad rdf:first sg:person.014427423617.32
132 rdf:rest N38eda68d2db94309a7daac6101d255c9
133 N68da4fdfca524af689c883ac4b752b46 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name DNA, Intergenic
135 rdf:type schema:DefinedTerm
136 N7651fd3552534b9093c0ced5dd3e28a4 schema:issueNumber 7690
137 rdf:type schema:PublicationIssue
138 N7a95f980c8794d0fbd2919b766c23705 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Pinus
140 rdf:type schema:DefinedTerm
141 N893ad31c93bc4a8d99e57b02f82a75dc rdf:first sg:person.01252002107.58
142 rdf:rest Ncbae1813e0fb4641932ea20fb68dd613
143 N8ced57c1489b4c5ea979430024387772 schema:name Springer Nature - SN SciGraph project
144 rdf:type schema:Organization
145 N93d8ffdffeb047b4a4c6004280f2d8ec rdf:first sg:person.0724307434.21
146 rdf:rest N17dc31ad734147e9bd5557249f29c6f6
147 N9874ce057ca94137b36fce384f18810b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Animals
149 rdf:type schema:DefinedTerm
150 N998c67ddfecd4ec5809867b892d761a6 rdf:first sg:person.01362467417.43
151 rdf:rest N4d4fd7f9dc654f8c980428b8c6750536
152 N9e56b731fa8a4c7f869c4f8f13903f04 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Mice
154 rdf:type schema:DefinedTerm
155 N9fec3127cf7c4fc78dd8a026f8fdd3af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Regeneration
157 rdf:type schema:DefinedTerm
158 Na2a9a0ca5a0c4b0b9f83594e084737a8 schema:name Molecular and Developmental Complexity Group, Unidad de Genómica Avanzada, Langebio-Cinvestav, Irapuato, Mexico
159 rdf:type schema:Organization
160 Na3388bad5fa74af7b7aab456e3dfbc8a schema:name dimensions_id
161 schema:value pub.1100587495
162 rdf:type schema:PropertyValue
163 Na35e5c8f40a347589c4bc497c9c2b4b0 rdf:first sg:person.01313562662.09
164 rdf:rest N93d8ffdffeb047b4a4c6004280f2d8ec
165 Na56ce4d26d274d3a92b99ba1d130ea80 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Terminal Repeat Sequences
167 rdf:type schema:DefinedTerm
168 Nb141b142216d4e0e8090b208058252f0 schema:name doi
169 schema:value 10.1038/nature25458
170 rdf:type schema:PropertyValue
171 Nbc2d5ea2b33b4de6af6b873ff4f9b6a8 schema:name pubmed_id
172 schema:value 29364872
173 rdf:type schema:PropertyValue
174 Nc017b1ec73a14f14845b9eb6b6812643 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Ambystoma mexicanum
176 rdf:type schema:DefinedTerm
177 Nc91ed3990e754fcda2acf4f788e0e43c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Genome
179 rdf:type schema:DefinedTerm
180 Ncbae1813e0fb4641932ea20fb68dd613 rdf:first sg:person.011232147010.31
181 rdf:rest N1a3c96e84ef847049d1ec9cb3c3aa316
182 Ncf67d38ee6564ee9ad0b86790f8bedbe schema:name readcube_id
183 schema:value 3764bbecc4f26991007592d2eb799bf86d8a7e0a668c1feddc9474b871ff62a6
184 rdf:type schema:PropertyValue
185 Nd78f90161ae548c8b14725b3ed48ce75 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Genomics
187 rdf:type schema:DefinedTerm
188 Ndbd1fc92df25429b80dd79daa29ecd4b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Homeodomain Proteins
190 rdf:type schema:DefinedTerm
191 Nde3a8dc4fe4b49368bd404c4fa969777 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Male
193 rdf:type schema:DefinedTerm
194 Ne3a787a4ebba42f8a432492b52be1f29 rdf:first sg:person.01021663747.70
195 rdf:rest N3f62d37dda7d469c9fd1a237a3ee71e1
196 Ne55c97b1d7ae434abea3b7a207a77692 rdf:first sg:person.01066232042.81
197 rdf:rest N47c0ee4f4806460099d3d167f88eeaf6
198 Ne812aa65f2224626a3f814658dc8b7be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Picea
200 rdf:type schema:DefinedTerm
201 Ne8fcaf398c524033b48b525e546ee829 rdf:first sg:person.07571072610.73
202 rdf:rest N0d7cfcb350b540bdafdfaf83ef9d0072
203 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
204 schema:name Biological Sciences
205 rdf:type schema:DefinedTerm
206 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
207 schema:name Genetics
208 rdf:type schema:DefinedTerm
209 sg:grant.5139536 http://pending.schema.org/fundedItem sg:pub.10.1038/nature25458
210 rdf:type schema:MonetaryGrant
211 sg:grant.6798223 http://pending.schema.org/fundedItem sg:pub.10.1038/nature25458
212 rdf:type schema:MonetaryGrant
213 sg:journal.1018957 schema:issn 0090-0028
214 1476-4687
215 schema:name Nature
216 rdf:type schema:Periodical
217 sg:person.01021663747.70 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
218 schema:familyName Tanaka
219 schema:givenName Elly M.
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021663747.70
221 rdf:type schema:Person
222 sg:person.01026214557.58 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
223 schema:familyName Young
224 schema:givenName George
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026214557.58
226 rdf:type schema:Person
227 sg:person.01040462140.83 schema:affiliation https://www.grid.ac/institutes/grid.470262.5
228 schema:familyName Cao
229 schema:givenName Han
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040462140.83
231 rdf:type schema:Person
232 sg:person.01066232042.81 schema:affiliation https://www.grid.ac/institutes/grid.5399.6
233 schema:familyName Habermann
234 schema:givenName Bianca
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066232042.81
236 rdf:type schema:Person
237 sg:person.01104135401.27 schema:affiliation https://www.grid.ac/institutes/grid.419560.f
238 schema:familyName Roscito
239 schema:givenName Juliana G.
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104135401.27
241 rdf:type schema:Person
242 sg:person.011232147010.31 schema:affiliation N3706e6adb1354a64a416919844522816
243 schema:familyName Cruz
244 schema:givenName Alfredo
245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011232147010.31
246 rdf:type schema:Person
247 sg:person.01227245513.51 schema:affiliation https://www.grid.ac/institutes/grid.424699.4
248 schema:familyName Schloissnig
249 schema:givenName Siegfried
250 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227245513.51
251 rdf:type schema:Person
252 sg:person.01252002107.58 schema:affiliation https://www.grid.ac/institutes/grid.424699.4
253 schema:familyName Powell
254 schema:givenName Sean
255 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252002107.58
256 rdf:type schema:Person
257 sg:person.01257413227.51 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
258 schema:familyName Knapp
259 schema:givenName Dunja
260 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257413227.51
261 rdf:type schema:Person
262 sg:person.01265276040.11 schema:affiliation https://www.grid.ac/institutes/grid.470262.5
263 schema:familyName Hastie
264 schema:givenName Alex R.
265 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265276040.11
266 rdf:type schema:Person
267 sg:person.01313562662.09 schema:affiliation https://www.grid.ac/institutes/grid.263785.d
268 schema:familyName Fei
269 schema:givenName Ji-Feng
270 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313562662.09
271 rdf:type schema:Person
272 sg:person.01362467417.43 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
273 schema:familyName Nowoshilow
274 schema:givenName Sergej
275 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362467417.43
276 rdf:type schema:Person
277 sg:person.014427423617.32 schema:affiliation https://www.grid.ac/institutes/grid.424699.4
278 schema:familyName Pippel
279 schema:givenName Martin
280 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014427423617.32
281 rdf:type schema:Person
282 sg:person.0602025320.59 schema:affiliation https://www.grid.ac/institutes/grid.470262.5
283 schema:familyName Pang
284 schema:givenName Andy W. C.
285 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602025320.59
286 rdf:type schema:Person
287 sg:person.0624077563.24 schema:affiliation https://www.grid.ac/institutes/grid.419560.f
288 schema:familyName Hiller
289 schema:givenName Michael
290 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624077563.24
291 rdf:type schema:Person
292 sg:person.0703367253.71 schema:affiliation https://www.grid.ac/institutes/grid.419537.d
293 schema:familyName Winkler
294 schema:givenName Sylke
295 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0703367253.71
296 rdf:type schema:Person
297 sg:person.0724307434.21 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
298 schema:familyName Dahl
299 schema:givenName Andreas
300 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724307434.21
301 rdf:type schema:Person
302 sg:person.07571072610.73 schema:affiliation Na2a9a0ca5a0c4b0b9f83594e084737a8
303 schema:familyName Falcon
304 schema:givenName Francisco
305 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07571072610.73
306 rdf:type schema:Person
307 sg:person.0761445171.42 schema:affiliation https://www.grid.ac/institutes/grid.419537.d
308 schema:familyName Myers
309 schema:givenName Eugene W.
310 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761445171.42
311 rdf:type schema:Person
312 sg:pub.10.1007/bf02108133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026184918
313 https://doi.org/10.1007/bf02108133
314 rdf:type schema:CreativeWork
315 sg:pub.10.1038/375791a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002863166
316 https://doi.org/10.1038/375791a0
317 rdf:type schema:CreativeWork
318 sg:pub.10.1038/nature16974 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053579355
319 https://doi.org/10.1038/nature16974
320 rdf:type schema:CreativeWork
321 sg:pub.10.1038/ncomms9684 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049186159
322 https://doi.org/10.1038/ncomms9684
323 rdf:type schema:CreativeWork
324 sg:pub.10.1038/srep16413 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021432877
325 https://doi.org/10.1038/srep16413
326 rdf:type schema:CreativeWork
327 sg:pub.10.1186/1471-2164-10-19 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028955530
328 https://doi.org/10.1186/1471-2164-10-19
329 rdf:type schema:CreativeWork
330 sg:pub.10.1186/1479-7364-7-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004498076
331 https://doi.org/10.1186/1479-7364-7-9
332 rdf:type schema:CreativeWork
333 https://app.dimensions.ai/details/publication/pub.1082886294 schema:CreativeWork
334 https://doi.org/10.1002/jez.1400920303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047991249
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1002/jez.1401270206 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033475744
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1016/j.cell.2016.05.038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030642172
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1016/j.celrep.2016.12.063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038046115
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1016/j.devcel.2016.10.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016891004
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1016/j.tibtech.2013.04.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031527623
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1016/j.ydbio.2009.12.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003640340
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1016/j.ydbio.2010.05.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038426842
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1016/j.ydbio.2016.05.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039084029
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1016/s0955-0674(96)80087-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013024036
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1016/s1534-5807(02)00288-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022443446
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1046/j.1524-475x.1996.40113.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1000488354
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1073/pnas.1501764112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026574330
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1083/jcb.200508001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019190533
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1091/mbc.e15-12-0821 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024483156
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1093/bioinformatics/btm071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014996474
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1093/gbe/evr139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001643244
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1093/gbe/evu135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028602770
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1093/gbe/evu143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029894232
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1093/gigascience/giw018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084184782
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1093/icb/icq022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038120000
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1093/nar/gkq1061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017494830
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1101/gad.301004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018737796
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1101/pdb.emo128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060408935
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1111/tpj.12886 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040889679
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1126/science.1098119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022514256
385 rdf:type schema:CreativeWork
386 https://doi.org/10.1126/science.1241796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008853694
387 rdf:type schema:CreativeWork
388 https://doi.org/10.1242/dev.00975 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036952394
389 rdf:type schema:CreativeWork
390 https://doi.org/10.1371/journal.pcbi.1002936 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035247495
391 rdf:type schema:CreativeWork
392 https://doi.org/10.1371/journal.pone.0061352 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034815022
393 rdf:type schema:CreativeWork
394 https://doi.org/10.1371/journal.pone.0157106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028179677
395 rdf:type schema:CreativeWork
396 https://www.grid.ac/institutes/grid.263785.d schema:alternateName South China Normal University
397 schema:name Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, China
398 rdf:type schema:Organization
399 https://www.grid.ac/institutes/grid.419537.d schema:alternateName Max Planck Institute of Molecular Cell Biology and Genetics
400 schema:name Center for Systems Biology, Dresden, Germany
401 Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
402 rdf:type schema:Organization
403 https://www.grid.ac/institutes/grid.419560.f schema:alternateName Max Planck Institute for the Physics of Complex Systems
404 schema:name Center for Systems Biology, Dresden, Germany
405 Max Planck Institute for the Physics of Complex Systems, Dresden, Germany
406 Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
407 rdf:type schema:Organization
408 https://www.grid.ac/institutes/grid.424699.4 schema:alternateName Heidelberg Institute for Theoretical Studies
409 schema:name Heidelberg Institute for Theoretical Studies, Heidelberg, Germany
410 rdf:type schema:Organization
411 https://www.grid.ac/institutes/grid.4488.0 schema:alternateName TU Dresden
412 schema:name DFG Research Center for Regenerative Therapies, Technische Universität Dresden, Dresden, Germany.
413 Deep Sequencing Group, Biotechnology Center (Biotec) Technische Universität Dresden, Dresden, Germany
414 Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
415 Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
416 rdf:type schema:Organization
417 https://www.grid.ac/institutes/grid.451388.3 schema:alternateName The Francis Crick Institute
418 schema:name The Francis Crick Institute, London, UK
419 rdf:type schema:Organization
420 https://www.grid.ac/institutes/grid.470262.5 schema:alternateName BioNano Genomics (United States)
421 schema:name Bionano Genomics, San Diego, California, USA
422 rdf:type schema:Organization
423 https://www.grid.ac/institutes/grid.5399.6 schema:alternateName Aix-Marseille University
424 schema:name IBDM – Institut de Biologie du Développement de Marseille, CNRS & Aix-Marseille Université, Marseille, France
425 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...