FOXO1 couples metabolic activity and growth state in the vascular endothelium View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-01-06

AUTHORS

Kerstin Wilhelm, Katharina Happel, Guy Eelen, Sandra Schoors, Mark F. Oellerich, Radiance Lim, Barbara Zimmermann, Irene M. Aspalter, Claudio A. Franco, Thomas Boettger, Thomas Braun, Marcus Fruttiger, Klaus Rajewsky, Charles Keller, Jens C. Brüning, Holger Gerhardt, Peter Carmeliet, Michael Potente

ABSTRACT

The transcription factor FOXO1 is identified as a crucial checkpoint of vascular growth, coupling the metabolic and proliferative activities of endothelial cells.

PAGES

216-220

References to SciGraph publications

  • 2002-09. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress in NATURE
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  • 2013-01-17. FOXOs: signalling integrators for homeostasis maintenance in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2014-07-09. Metabolism of stromal and immune cells in health and disease in NATURE
  • 2003-09-11. An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets in GENOME BIOLOGY
  • 2011-04-17. Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase in NATURE
  • 2008-04-28. An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors in NATURE GENETICS
  • 2005-11-06. Oncogenic pathway signatures in human cancers as a guide to targeted therapies in NATURE
  • 2013-01-31. The embryonic mouse hindbrain as a qualitative and quantitative model for studying the molecular and cellular mechanisms of angiogenesis in NATURE PROTOCOLS
  • 2007-06. Molecular regulation of angiogenesis and lymphangiogenesis in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature16498

    DOI

    http://dx.doi.org/10.1038/nature16498

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1000797964

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26735015


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