Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-07

AUTHORS

Paul A. Northcott, Catherine Lee, Thomas Zichner, Adrian M. Stütz, Serap Erkek, Daisuke Kawauchi, David J. H. Shih, Volker Hovestadt, Marc Zapatka, Dominik Sturm, David T. W. Jones, Marcel Kool, Marc Remke, Florence M. G. Cavalli, Scott Zuyderduyn, Gary D. Bader, Scott VandenBerg, Lourdes Adriana Esparza, Marina Ryzhova, Wei Wang, Andrea Wittmann, Sebastian Stark, Laura Sieber, Huriye Seker-Cin, Linda Linke, Fabian Kratochwil, Natalie Jäger, Ivo Buchhalter, Charles D. Imbusch, Gideon Zipprich, Benjamin Raeder, Sabine Schmidt, Nicolle Diessl, Stephan Wolf, Stefan Wiemann, Benedikt Brors, Chris Lawerenz, Jürgen Eils, Hans-Jörg Warnatz, Thomas Risch, Marie-Laure Yaspo, Ursula D. Weber, Cynthia C. Bartholomae, Christof von Kalle, Eszter Turányi, Peter Hauser, Emma Sanden, Anna Darabi, Peter Siesjö, Jaroslav Sterba, Karel Zitterbart, David Sumerauer, Peter van Sluis, Rogier Versteeg, Richard Volckmann, Jan Koster, Martin U. Schuhmann, Martin Ebinger, H. Leighton Grimes, Giles W. Robinson, Amar Gajjar, Martin Mynarek, Katja von Hoff, Stefan Rutkowski, Torsten Pietsch, Wolfram Scheurlen, Jörg Felsberg, Guido Reifenberger, Andreas E. Kulozik, Andreas von Deimling, Olaf Witt, Roland Eils, Richard J. Gilbertson, Andrey Korshunov, Michael D. Taylor, Peter Lichter, Jan O. Korbel, Robert J. Wechsler-Reya, Stefan M. Pfister

ABSTRACT

Medulloblastoma is a highly malignant paediatric brain tumour currently treated with a combination of surgery, radiation and chemotherapy, posing a considerable burden of toxicity to the developing child. Genomics has illuminated the extensive intertumoral heterogeneity of medulloblastoma, identifying four distinct molecular subgroups. Group 3 and group 4 subgroup medulloblastomas account for most paediatric cases; yet, oncogenic drivers for these subtypes remain largely unidentified. Here we describe a series of prevalent, highly disparate genomic structural variants, restricted to groups 3 and 4, resulting in specific and mutually exclusive activation of the growth factor independent 1 family proto-oncogenes, GFI1 and GFI1B. Somatic structural variants juxtapose GFI1 or GFI1B coding sequences proximal to active enhancer elements, including super-enhancers, instigating oncogenic activity. Our results, supported by evidence from mouse models, identify GFI1 and GFI1B as prominent medulloblastoma oncogenes and implicate 'enhancer hijacking' as an efficient mechanism driving oncogene activation in a childhood cancer. More... »

PAGES

428

References to SciGraph publications

  • 2011-05-05. Mapping and analysis of chromatin state dynamics in nine human cell types in NATURE
  • 2005-06. Isolation of neural stem cells from the postnatal cerebellum in NATURE NEUROSCIENCE
  • 2004-10. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells in NATURE
  • 2010-12. Subtypes of medulloblastoma have distinct developmental origins in NATURE
  • 2013-06. Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays in ACTA NEUROPATHOLOGICA
  • 2012-08. Novel mutations target distinct subgroups of medulloblastoma in NATURE
  • 2012-11. An integrated map of genetic variation from 1,092 human genomes in NATURE
  • 2014-06. Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing in NATURE
  • 2012-12. Medulloblastomics: the end of the beginning in NATURE REVIEWS CANCER
  • 2013-11. Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer in NATURE REVIEWS GENETICS
  • 1998-11. Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis in ONCOGENE
  • 2012-12. Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing in NATURE GENETICS
  • 2012-08. Dissecting the genomic complexity underlying medulloblastoma in NATURE
  • 2012-04. Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples in ACTA NEUROPATHOLOGICA
  • 2003-07. Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2 in NATURE GENETICS
  • 2011-03. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells in NATURE
  • 2012-08. Subgroup-specific structural variation across 1,000 medulloblastoma genomes in NATURE
  • 2010-01. A census of amplified and overexpressed human cancer genes in NATURE REVIEWS CANCER
  • 2011-08. TopHat-Fusion: an algorithm for discovery of novel fusion transcripts in GENOME BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature13379

    DOI

    http://dx.doi.org/10.1038/nature13379

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1014600483

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25043047


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    904 Division of Molecular Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany
    905 Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany
    906 Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany
    907 Division of Translational Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, Heidelberg 69120, Germany
    908 Genomics and Proteomics Core Facility, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany
    909 Heidelberg Center for Personalised Oncology (DKFZ-HIPO), Im Neuenheimer Feld 280, Heidelberg 69120, Germany
    910 rdf:type schema:Organization
    911 https://www.grid.ac/institutes/grid.7700.0 schema:alternateName Heidelberg University
    912 schema:name Department of Neuropathology, University of Heidelberg, Im Neuenheimer Feld 220, Heidelberg 69120, Germany
    913 rdf:type schema:Organization
     




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