N6-methyladenosine-dependent regulation of messenger RNA stability View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-11-27

AUTHORS

Xiao Wang, Zhike Lu, Adrian Gomez, Gary C. Hon, Yanan Yue, Dali Han, Ye Fu, Marc Parisien, Qing Dai, Guifang Jia, Bing Ren, Tao Pan, Chuan He

ABSTRACT

The mRNAs of higher eukaryotes are extensively modified internally with N6-methyladenosine, but the specific functional role of this modification has been unclear; here this modification on mRNA is shown to be recognized by several proteins, the modification and its recognition serve to regulate the RNA’s lifetime.

PAGES

117-120

Journal

TITLE

Nature

ISSUE

7481

VOLUME

505

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature12730

DOI

http://dx.doi.org/10.1038/nature12730

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045996872

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24284625


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