The shaping and functional consequences of the microRNA landscape in breast cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-05-05

AUTHORS

Heidi Dvinge, Anna Git, Stefan Gräf, Mali Salmon-Divon, Christina Curtis, Andrea Sottoriva, Yongjun Zhao, Martin Hirst, Javier Armisen, Eric A. Miska, Suet-Feung Chin, Elena Provenzano, Gulisa Turashvili, Andrew Green, Ian Ellis, Sam Aparicio, Carlos Caldas

ABSTRACT

MicroRNA profiling of 1,302 human breast tumour samples provides an overview of the miRNA landscape and its regulation, revealing context-dependent interactions, broad prognostic value of miRNA signatures and an important modulatory role for miRNAs in the biology of breast tumours devoid of copy-number aberrations.

PAGES

378-382

Journal

TITLE

Nature

ISSUE

7449

VOLUME

497

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature12108

DOI

http://dx.doi.org/10.1038/nature12108

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027957670

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23644459


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Algorithms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breast Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Copy Number Variations", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Profiling", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation, Neoplastic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kaplan-Meier Estimate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "MicroRNAs", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proportional Hazards Models", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Neoplasm", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Present addresses: Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA (H.D.); Department of Medicine, University of Cambridge, Addenbrooke\u2019s Hospital, Hills Road, Cambridge CB2 0QQ, UK (S.G.).", 
          "id": "http://www.grid.ac/institutes/grid.270240.3", 
          "name": [
            "Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK", 
            "Present addresses: Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA (H.D.); Department of Medicine, University of Cambridge, Addenbrooke\u2019s Hospital, Hills Road, Cambridge CB2 0QQ, UK (S.G.)."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dvinge", 
        "givenName": "Heidi", 
        "id": "sg:person.0777053256.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777053256.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK", 
          "id": "http://www.grid.ac/institutes/grid.5335.0", 
          "name": [
            "Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Git", 
        "givenName": "Anna", 
        "id": "sg:person.01027171227.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027171227.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Present addresses: Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA (H.D.); Department of Medicine, University of Cambridge, Addenbrooke\u2019s Hospital, Hills Road, Cambridge CB2 0QQ, UK (S.G.).", 
          "id": "http://www.grid.ac/institutes/grid.270240.3", 
          "name": [
            "Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK", 
            "Present addresses: Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA (H.D.); Department of Medicine, University of Cambridge, Addenbrooke\u2019s Hospital, Hills Road, Cambridge CB2 0QQ, UK (S.G.)."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gr\u00e4f", 
        "givenName": "Stefan", 
        "id": "sg:person.0664556564.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664556564.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Molecular Biology, Ariel University Center of Samaria, 40700, Ariel, Israel", 
          "id": "http://www.grid.ac/institutes/grid.411434.7", 
          "name": [
            "European Molecular Biology Laboratory\u2013European Bioinformatics Institute, Wellcome Trust Genome Campus, CB10 1SD, Cambridge, UK", 
            "Department of Molecular Biology, Ariel University Center of Samaria, 40700, Ariel, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Salmon-Divon", 
        "givenName": "Mali", 
        "id": "sg:person.01171340374.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171340374.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Preventive Medicine, University of Southern California, 90033, Los Angeles, California, USA", 
          "id": "http://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Preventive Medicine, University of Southern California, 90033, Los Angeles, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Curtis", 
        "givenName": "Christina", 
        "id": "sg:person.0674303034.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674303034.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Preventive Medicine, University of Southern California, 90033, Los Angeles, California, USA", 
          "id": "http://www.grid.ac/institutes/grid.42505.36", 
          "name": [
            "Department of Preventive Medicine, University of Southern California, 90033, Los Angeles, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sottoriva", 
        "givenName": "Andrea", 
        "id": "sg:person.0743051442.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743051442.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, Canada", 
          "id": "http://www.grid.ac/institutes/grid.17091.3e", 
          "name": [
            "Genome Sciences Centre, BC Cancer Agency, V5Z 1L3, 675 West 10th Avenue, Vancouver, Canada", 
            "Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhao", 
        "givenName": "Yongjun", 
        "id": "sg:person.013415760017.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013415760017.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, Canada", 
          "id": "http://www.grid.ac/institutes/grid.17091.3e", 
          "name": [
            "Genome Sciences Centre, BC Cancer Agency, V5Z 1L3, 675 West 10th Avenue, Vancouver, Canada", 
            "Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hirst", 
        "givenName": "Martin", 
        "id": "sg:person.0601713543.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601713543.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wellcome Trust Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, CB2 1QN, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, UK", 
          "id": "http://www.grid.ac/institutes/grid.5335.0", 
          "name": [
            "Wellcome Trust Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, CB2 1QN, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Armisen", 
        "givenName": "Javier", 
        "id": "sg:person.01137001505.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137001505.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wellcome Trust Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, CB2 1QN, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, UK", 
          "id": "http://www.grid.ac/institutes/grid.5335.0", 
          "name": [
            "Wellcome Trust Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, CB2 1QN, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miska", 
        "givenName": "Eric A.", 
        "id": "sg:person.01343400113.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343400113.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK", 
          "id": "http://www.grid.ac/institutes/grid.5335.0", 
          "name": [
            "Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chin", 
        "givenName": "Suet-Feung", 
        "id": "sg:person.01256717077.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256717077.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambridge Breast Unit, Addenbrooke\u2019s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, CB2 2QQ, Cambridge, UK", 
          "id": "http://www.grid.ac/institutes/grid.120073.7", 
          "name": [
            "Cambridge Breast Unit, Addenbrooke\u2019s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, CB2 2QQ, Cambridge, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Provenzano", 
        "givenName": "Elena", 
        "id": "sg:person.0764233660.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764233660.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Molecular Oncology, V5Z 1L3, British Columbia Cancer Research Centre, Vancouver, Canada", 
          "id": "http://www.grid.ac/institutes/grid.248762.d", 
          "name": [
            "Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, Canada", 
            "Molecular Oncology, V5Z 1L3, British Columbia Cancer Research Centre, Vancouver, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Turashvili", 
        "givenName": "Gulisa", 
        "id": "sg:person.013356375234.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013356375234.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Histopathology, School of Molecular Medical Sciences, University of Nottingham, NG5 1PB, Nottingham, UK", 
          "id": "http://www.grid.ac/institutes/grid.4563.4", 
          "name": [
            "Department of Histopathology, School of Molecular Medical Sciences, University of Nottingham, NG5 1PB, Nottingham, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Green", 
        "givenName": "Andrew", 
        "id": "sg:person.016416665412.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016416665412.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Histopathology, School of Molecular Medical Sciences, University of Nottingham, NG5 1PB, Nottingham, UK", 
          "id": "http://www.grid.ac/institutes/grid.4563.4", 
          "name": [
            "Department of Histopathology, School of Molecular Medical Sciences, University of Nottingham, NG5 1PB, Nottingham, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ellis", 
        "givenName": "Ian", 
        "id": "sg:person.01054612302.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054612302.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Molecular Oncology, V5Z 1L3, British Columbia Cancer Research Centre, Vancouver, Canada", 
          "id": "http://www.grid.ac/institutes/grid.248762.d", 
          "name": [
            "Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, Canada", 
            "Molecular Oncology, V5Z 1L3, British Columbia Cancer Research Centre, Vancouver, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aparicio", 
        "givenName": "Sam", 
        "id": "sg:person.0720022504.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0720022504.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambridge Experimental Cancer Medicine Centre, CB2 0RE, Cambridge, UK", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK", 
            "Cambridge Breast Unit, Addenbrooke\u2019s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, CB2 2QQ, Cambridge, UK", 
            "Cambridge Experimental Cancer Medicine Centre, CB2 0RE, Cambridge, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Caldas", 
        "givenName": "Carlos", 
        "id": "sg:person.01072152660.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072152660.47"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/bcr2109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050872080", 
          "https://doi.org/10.1186/bcr2109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10753-012-9467-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030627441", 
          "https://doi.org/10.1007/s10753-012-9467-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature11412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024942368", 
          "https://doi.org/10.1038/nature11412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10983", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014607335", 
          "https://doi.org/10.1038/nature10983"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg2843", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028796698", 
          "https://doi.org/10.1038/nrg2843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35021093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033846543", 
          "https://doi.org/10.1038/35021093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt.1563", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026698816", 
          "https://doi.org/10.1038/nbt.1563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/gb-2007-8-8-r157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052735338", 
          "https://doi.org/10.1186/gb-2007-8-8-r157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/gb-2007-8-10-r214", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008503544", 
          "https://doi.org/10.1186/gb-2007-8-10-r214"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-05-05", 
    "datePublishedReg": "2013-05-05", 
    "description": "MicroRNA profiling of 1,302 human breast tumour samples provides an overview of the miRNA landscape and its regulation, revealing context-dependent interactions, broad prognostic value of miRNA signatures and an important modulatory role for miRNAs in the biology of breast tumours devoid of copy-number aberrations.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/nature12108", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7449", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "497"
      }
    ], 
    "keywords": [
      "human breast tumor samples", 
      "important modulatory role", 
      "breast tumor samples", 
      "prognostic value", 
      "breast cancer", 
      "breast tumors", 
      "modulatory role", 
      "tumor samples", 
      "miRNA signature", 
      "copy number aberrations", 
      "microRNA profiling", 
      "functional consequences", 
      "context-dependent interactions", 
      "tumors", 
      "miRNA landscape", 
      "cancer", 
      "microRNA landscape", 
      "aberrations", 
      "miRNAs", 
      "role", 
      "profiling", 
      "regulation", 
      "samples", 
      "landscape", 
      "biology", 
      "consequences", 
      "overview", 
      "values", 
      "signatures", 
      "interaction", 
      "shaping"
    ], 
    "name": "The shaping and functional consequences of the microRNA landscape in breast cancer", 
    "pagination": "378-382", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1027957670"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature12108"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23644459"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature12108", 
      "https://app.dimensions.ai/details/publication/pub.1027957670"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-11-24T20:57", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_596.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/nature12108"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature12108'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature12108'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature12108'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature12108'


 

This table displays all metadata directly associated to this object as RDF triples.

332 TRIPLES      21 PREDICATES      80 URIs      63 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature12108 schema:about N0bb48695d68c4506b7a9dbac9e210627
2 N2deee76405a04968b6e3bcf50e27dc51
3 N310e9125c69543f59eeff65bac053917
4 N4e7c39e8f628496fab5531f7968283df
5 N6f56395445e342ccaa4357e46cb351ff
6 N859b4cf6f93845b3adfc52821cbf37e6
7 N86b53161432e44acb223ed9e98694b8e
8 N8b9ffd05460943e585a828178b1b1dc8
9 N8f0ca8adf19c4797990cebbd64b27de6
10 Nafdf3e8285a5462b8bb0abb36a5bfb8a
11 Nbd73b9aecb06409389215b9bc8568fd9
12 Nd6d8d119f6784cb691d6e750d09c1e2a
13 Ndb9ecaf41d86444caf62d5f7918b4aa4
14 Nef5a52a75c8a498a90f1aca15c398c34
15 Nfced7f31115a4b9c84096b462b337f45
16 anzsrc-for:11
17 anzsrc-for:1112
18 schema:author N03068898ae1549c393f2132b064898fc
19 schema:citation sg:pub.10.1007/s10753-012-9467-0
20 sg:pub.10.1038/35021093
21 sg:pub.10.1038/nature10983
22 sg:pub.10.1038/nature11412
23 sg:pub.10.1038/nbt.1563
24 sg:pub.10.1038/nrg2843
25 sg:pub.10.1186/bcr2109
26 sg:pub.10.1186/gb-2007-8-10-r214
27 sg:pub.10.1186/gb-2007-8-8-r157
28 schema:datePublished 2013-05-05
29 schema:datePublishedReg 2013-05-05
30 schema:description MicroRNA profiling of 1,302 human breast tumour samples provides an overview of the miRNA landscape and its regulation, revealing context-dependent interactions, broad prognostic value of miRNA signatures and an important modulatory role for miRNAs in the biology of breast tumours devoid of copy-number aberrations.
31 schema:genre article
32 schema:isAccessibleForFree false
33 schema:isPartOf Nc0000ffbbd6e4fbf9cca9f91169819b4
34 Nf47558e363bf414eb07af0d95bd7ad85
35 sg:journal.1018957
36 schema:keywords aberrations
37 biology
38 breast cancer
39 breast tumor samples
40 breast tumors
41 cancer
42 consequences
43 context-dependent interactions
44 copy number aberrations
45 functional consequences
46 human breast tumor samples
47 important modulatory role
48 interaction
49 landscape
50 miRNA landscape
51 miRNA signature
52 miRNAs
53 microRNA landscape
54 microRNA profiling
55 modulatory role
56 overview
57 profiling
58 prognostic value
59 regulation
60 role
61 samples
62 shaping
63 signatures
64 tumor samples
65 tumors
66 values
67 schema:name The shaping and functional consequences of the microRNA landscape in breast cancer
68 schema:pagination 378-382
69 schema:productId N8a89bedbf82d4bd182d3202ed07adfc7
70 N9c2be4e4d1be4b289526196f4700ee09
71 Nc8f1586e7cbc4f058df48488c35ddf27
72 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027957670
73 https://doi.org/10.1038/nature12108
74 schema:sdDatePublished 2022-11-24T20:57
75 schema:sdLicense https://scigraph.springernature.com/explorer/license/
76 schema:sdPublisher Nb72f42b9aa8248bfa3c975c6fc7bdddf
77 schema:url https://doi.org/10.1038/nature12108
78 sgo:license sg:explorer/license/
79 sgo:sdDataset articles
80 rdf:type schema:ScholarlyArticle
81 N03068898ae1549c393f2132b064898fc rdf:first sg:person.0777053256.58
82 rdf:rest N5c857b004c3c47978c305f52093e69e8
83 N044ccb9babd24fa181d7e7fc37ebda67 rdf:first sg:person.01072152660.47
84 rdf:rest rdf:nil
85 N0ba1437aa39d4b0587673131d1ca70da rdf:first sg:person.0764233660.04
86 rdf:rest N25c67be6b5a24a028b1f13857c92a6c1
87 N0bb48695d68c4506b7a9dbac9e210627 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Gene Expression Regulation, Neoplastic
89 rdf:type schema:DefinedTerm
90 N25c67be6b5a24a028b1f13857c92a6c1 rdf:first sg:person.013356375234.86
91 rdf:rest N2d3ee8afef7243c082cc48127b9072d4
92 N2d3ee8afef7243c082cc48127b9072d4 rdf:first sg:person.016416665412.02
93 rdf:rest N38fe35b6c9da47c0b94330dd8a5374f3
94 N2deee76405a04968b6e3bcf50e27dc51 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Breast Neoplasms
96 rdf:type schema:DefinedTerm
97 N310e9125c69543f59eeff65bac053917 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name RNA, Messenger
99 rdf:type schema:DefinedTerm
100 N36bce6a3e07b4cc28e4de3635c9fbfc8 rdf:first sg:person.0720022504.02
101 rdf:rest N044ccb9babd24fa181d7e7fc37ebda67
102 N38fe35b6c9da47c0b94330dd8a5374f3 rdf:first sg:person.01054612302.65
103 rdf:rest N36bce6a3e07b4cc28e4de3635c9fbfc8
104 N4be3bfc6d55e499989db7a64dc59df23 rdf:first sg:person.0601713543.66
105 rdf:rest Nba0389d80e16490190beb5e86669d75b
106 N4e7c39e8f628496fab5531f7968283df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Gene Expression Profiling
108 rdf:type schema:DefinedTerm
109 N5bbfab3ea58f48aabe28de2b430d683a rdf:first sg:person.01256717077.95
110 rdf:rest N0ba1437aa39d4b0587673131d1ca70da
111 N5c857b004c3c47978c305f52093e69e8 rdf:first sg:person.01027171227.72
112 rdf:rest Nadff0a6446094bff84b13acb9393dbd5
113 N6f56395445e342ccaa4357e46cb351ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Follow-Up Studies
115 rdf:type schema:DefinedTerm
116 N859b4cf6f93845b3adfc52821cbf37e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Female
118 rdf:type schema:DefinedTerm
119 N86b53161432e44acb223ed9e98694b8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Humans
121 rdf:type schema:DefinedTerm
122 N8a89bedbf82d4bd182d3202ed07adfc7 schema:name doi
123 schema:value 10.1038/nature12108
124 rdf:type schema:PropertyValue
125 N8b9ffd05460943e585a828178b1b1dc8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Algorithms
127 rdf:type schema:DefinedTerm
128 N8f0ca8adf19c4797990cebbd64b27de6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name RNA, Neoplasm
130 rdf:type schema:DefinedTerm
131 N9c2be4e4d1be4b289526196f4700ee09 schema:name pubmed_id
132 schema:value 23644459
133 rdf:type schema:PropertyValue
134 Nadff0a6446094bff84b13acb9393dbd5 rdf:first sg:person.0664556564.73
135 rdf:rest Ne44deecf130644b7a5d2abbd5f6df8a3
136 Nafdf3e8285a5462b8bb0abb36a5bfb8a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name DNA Copy Number Variations
138 rdf:type schema:DefinedTerm
139 Nb4cc2581fd4f4f6c9ab6fcca813556f1 rdf:first sg:person.0743051442.75
140 rdf:rest Nd07b9c8fb27b4f90a0e184078c50d029
141 Nb72f42b9aa8248bfa3c975c6fc7bdddf schema:name Springer Nature - SN SciGraph project
142 rdf:type schema:Organization
143 Nba0389d80e16490190beb5e86669d75b rdf:first sg:person.01137001505.83
144 rdf:rest Nc2559bf0c4524600ba813c221a56b06d
145 Nbd73b9aecb06409389215b9bc8568fd9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Prognosis
147 rdf:type schema:DefinedTerm
148 Nc0000ffbbd6e4fbf9cca9f91169819b4 schema:issueNumber 7449
149 rdf:type schema:PublicationIssue
150 Nc2559bf0c4524600ba813c221a56b06d rdf:first sg:person.01343400113.94
151 rdf:rest N5bbfab3ea58f48aabe28de2b430d683a
152 Nc8f1586e7cbc4f058df48488c35ddf27 schema:name dimensions_id
153 schema:value pub.1027957670
154 rdf:type schema:PropertyValue
155 Nd07b9c8fb27b4f90a0e184078c50d029 rdf:first sg:person.013415760017.30
156 rdf:rest N4be3bfc6d55e499989db7a64dc59df23
157 Nd6d8d119f6784cb691d6e750d09c1e2a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Proportional Hazards Models
159 rdf:type schema:DefinedTerm
160 Ndb9ecaf41d86444caf62d5f7918b4aa4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name MicroRNAs
162 rdf:type schema:DefinedTerm
163 Ne44deecf130644b7a5d2abbd5f6df8a3 rdf:first sg:person.01171340374.64
164 rdf:rest Nfd9ebdf460d14044be2f06da714fadc8
165 Nef5a52a75c8a498a90f1aca15c398c34 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Genome, Human
167 rdf:type schema:DefinedTerm
168 Nf47558e363bf414eb07af0d95bd7ad85 schema:volumeNumber 497
169 rdf:type schema:PublicationVolume
170 Nfced7f31115a4b9c84096b462b337f45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Kaplan-Meier Estimate
172 rdf:type schema:DefinedTerm
173 Nfd9ebdf460d14044be2f06da714fadc8 rdf:first sg:person.0674303034.04
174 rdf:rest Nb4cc2581fd4f4f6c9ab6fcca813556f1
175 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
176 schema:name Medical and Health Sciences
177 rdf:type schema:DefinedTerm
178 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
179 schema:name Oncology and Carcinogenesis
180 rdf:type schema:DefinedTerm
181 sg:journal.1018957 schema:issn 0028-0836
182 1476-4687
183 schema:name Nature
184 schema:publisher Springer Nature
185 rdf:type schema:Periodical
186 sg:person.01027171227.72 schema:affiliation grid-institutes:grid.5335.0
187 schema:familyName Git
188 schema:givenName Anna
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027171227.72
190 rdf:type schema:Person
191 sg:person.01054612302.65 schema:affiliation grid-institutes:grid.4563.4
192 schema:familyName Ellis
193 schema:givenName Ian
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054612302.65
195 rdf:type schema:Person
196 sg:person.01072152660.47 schema:affiliation grid-institutes:None
197 schema:familyName Caldas
198 schema:givenName Carlos
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072152660.47
200 rdf:type schema:Person
201 sg:person.01137001505.83 schema:affiliation grid-institutes:grid.5335.0
202 schema:familyName Armisen
203 schema:givenName Javier
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137001505.83
205 rdf:type schema:Person
206 sg:person.01171340374.64 schema:affiliation grid-institutes:grid.411434.7
207 schema:familyName Salmon-Divon
208 schema:givenName Mali
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171340374.64
210 rdf:type schema:Person
211 sg:person.01256717077.95 schema:affiliation grid-institutes:grid.5335.0
212 schema:familyName Chin
213 schema:givenName Suet-Feung
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256717077.95
215 rdf:type schema:Person
216 sg:person.013356375234.86 schema:affiliation grid-institutes:grid.248762.d
217 schema:familyName Turashvili
218 schema:givenName Gulisa
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013356375234.86
220 rdf:type schema:Person
221 sg:person.013415760017.30 schema:affiliation grid-institutes:grid.17091.3e
222 schema:familyName Zhao
223 schema:givenName Yongjun
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013415760017.30
225 rdf:type schema:Person
226 sg:person.01343400113.94 schema:affiliation grid-institutes:grid.5335.0
227 schema:familyName Miska
228 schema:givenName Eric A.
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343400113.94
230 rdf:type schema:Person
231 sg:person.016416665412.02 schema:affiliation grid-institutes:grid.4563.4
232 schema:familyName Green
233 schema:givenName Andrew
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016416665412.02
235 rdf:type schema:Person
236 sg:person.0601713543.66 schema:affiliation grid-institutes:grid.17091.3e
237 schema:familyName Hirst
238 schema:givenName Martin
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601713543.66
240 rdf:type schema:Person
241 sg:person.0664556564.73 schema:affiliation grid-institutes:grid.270240.3
242 schema:familyName Gräf
243 schema:givenName Stefan
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664556564.73
245 rdf:type schema:Person
246 sg:person.0674303034.04 schema:affiliation grid-institutes:grid.42505.36
247 schema:familyName Curtis
248 schema:givenName Christina
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674303034.04
250 rdf:type schema:Person
251 sg:person.0720022504.02 schema:affiliation grid-institutes:grid.248762.d
252 schema:familyName Aparicio
253 schema:givenName Sam
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0720022504.02
255 rdf:type schema:Person
256 sg:person.0743051442.75 schema:affiliation grid-institutes:grid.42505.36
257 schema:familyName Sottoriva
258 schema:givenName Andrea
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743051442.75
260 rdf:type schema:Person
261 sg:person.0764233660.04 schema:affiliation grid-institutes:grid.120073.7
262 schema:familyName Provenzano
263 schema:givenName Elena
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764233660.04
265 rdf:type schema:Person
266 sg:person.0777053256.58 schema:affiliation grid-institutes:grid.270240.3
267 schema:familyName Dvinge
268 schema:givenName Heidi
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777053256.58
270 rdf:type schema:Person
271 sg:pub.10.1007/s10753-012-9467-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030627441
272 https://doi.org/10.1007/s10753-012-9467-0
273 rdf:type schema:CreativeWork
274 sg:pub.10.1038/35021093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033846543
275 https://doi.org/10.1038/35021093
276 rdf:type schema:CreativeWork
277 sg:pub.10.1038/nature10983 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014607335
278 https://doi.org/10.1038/nature10983
279 rdf:type schema:CreativeWork
280 sg:pub.10.1038/nature11412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024942368
281 https://doi.org/10.1038/nature11412
282 rdf:type schema:CreativeWork
283 sg:pub.10.1038/nbt.1563 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026698816
284 https://doi.org/10.1038/nbt.1563
285 rdf:type schema:CreativeWork
286 sg:pub.10.1038/nrg2843 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028796698
287 https://doi.org/10.1038/nrg2843
288 rdf:type schema:CreativeWork
289 sg:pub.10.1186/bcr2109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050872080
290 https://doi.org/10.1186/bcr2109
291 rdf:type schema:CreativeWork
292 sg:pub.10.1186/gb-2007-8-10-r214 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008503544
293 https://doi.org/10.1186/gb-2007-8-10-r214
294 rdf:type schema:CreativeWork
295 sg:pub.10.1186/gb-2007-8-8-r157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052735338
296 https://doi.org/10.1186/gb-2007-8-8-r157
297 rdf:type schema:CreativeWork
298 grid-institutes:None schema:alternateName Cambridge Experimental Cancer Medicine Centre, CB2 0RE, Cambridge, UK
299 schema:name Cambridge Breast Unit, Addenbrooke’s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, CB2 2QQ, Cambridge, UK
300 Cambridge Experimental Cancer Medicine Centre, CB2 0RE, Cambridge, UK
301 Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
302 rdf:type schema:Organization
303 grid-institutes:grid.120073.7 schema:alternateName Cambridge Breast Unit, Addenbrooke’s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, CB2 2QQ, Cambridge, UK
304 schema:name Cambridge Breast Unit, Addenbrooke’s Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, CB2 2QQ, Cambridge, UK
305 rdf:type schema:Organization
306 grid-institutes:grid.17091.3e schema:alternateName Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, Canada
307 schema:name Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, Canada
308 Genome Sciences Centre, BC Cancer Agency, V5Z 1L3, 675 West 10th Avenue, Vancouver, Canada
309 rdf:type schema:Organization
310 grid-institutes:grid.248762.d schema:alternateName Molecular Oncology, V5Z 1L3, British Columbia Cancer Research Centre, Vancouver, Canada
311 schema:name Department of Pathology and Laboratory Medicine, University of British Columbia, V6T 2B5, Vancouver, Canada
312 Molecular Oncology, V5Z 1L3, British Columbia Cancer Research Centre, Vancouver, Canada
313 rdf:type schema:Organization
314 grid-institutes:grid.270240.3 schema:alternateName Present addresses: Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA (H.D.); Department of Medicine, University of Cambridge, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 0QQ, UK (S.G.).
315 schema:name Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
316 Present addresses: Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA (H.D.); Department of Medicine, University of Cambridge, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 0QQ, UK (S.G.).
317 rdf:type schema:Organization
318 grid-institutes:grid.411434.7 schema:alternateName Department of Molecular Biology, Ariel University Center of Samaria, 40700, Ariel, Israel
319 schema:name Department of Molecular Biology, Ariel University Center of Samaria, 40700, Ariel, Israel
320 European Molecular Biology Laboratory–European Bioinformatics Institute, Wellcome Trust Genome Campus, CB10 1SD, Cambridge, UK
321 rdf:type schema:Organization
322 grid-institutes:grid.42505.36 schema:alternateName Department of Preventive Medicine, University of Southern California, 90033, Los Angeles, California, USA
323 schema:name Department of Preventive Medicine, University of Southern California, 90033, Los Angeles, California, USA
324 rdf:type schema:Organization
325 grid-institutes:grid.4563.4 schema:alternateName Department of Histopathology, School of Molecular Medical Sciences, University of Nottingham, NG5 1PB, Nottingham, UK
326 schema:name Department of Histopathology, School of Molecular Medical Sciences, University of Nottingham, NG5 1PB, Nottingham, UK
327 rdf:type schema:Organization
328 grid-institutes:grid.5335.0 schema:alternateName Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
329 Wellcome Trust Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, CB2 1QN, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, UK
330 schema:name Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
331 Wellcome Trust Cancer Research UK Gurdon Institute and Department of Biochemistry, University of Cambridge, CB2 1QN, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, UK
332 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...