Functional and evolutionary insight from the crystal structure of rubella virus protein E1 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-01-06

AUTHORS

Rebecca M. DuBois, Marie-Christine Vaney, M. Alejandra Tortorici, Rana Al Kurdi, Giovanna Barba-Spaeth, Thomas Krey, Félix A. Rey

ABSTRACT

The crystal structure of rubella virus E1 glycoprotein in its post-fusion form reveals a class II fusion protein with distinct features so far unseen in any other crystallized fusion protein; the location of an antibody-neutralization epitope also suggests that rubella-specific antibodies may function through prevention of E1 glycoprotein trimer formation during cell entry. More... »

PAGES

552-556

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature11741

DOI

http://dx.doi.org/10.1038/nature11741

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049536961

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23292515


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