Functional interactions between the gut microbiota and host metabolism View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-09

AUTHORS

Valentina Tremaroli, Fredrik Bäckhed

ABSTRACT

The link between the microbes in the human gut and the development of obesity, cardiovascular disease and metabolic syndromes, such as type 2 diabetes, is becoming clearer. However, because of the complexity of the microbial community, the functional connections are less well understood. Studies in both mice and humans are helping to show what effect the gut microbiota has on host metabolism by improving energy yield from food and modulating dietary or the host-derived compounds that alter host metabolic pathways. Through increased knowledge of the mechanisms involved in the interactions between the microbiota and its host, we will be in a better position to develop treatments for metabolic disease. More... »

PAGES

242

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature11552

    DOI

    http://dx.doi.org/10.1038/nature11552

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1004952443

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22972297


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