Apolipoprotein E controls cerebrovascular integrity via cyclophilin A View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-05-16

AUTHORS

Robert D. Bell, Ethan A. Winkler, Itender Singh, Abhay P. Sagare, Rashid Deane, Zhenhua Wu, David M. Holtzman, Christer Betsholtz, Annika Armulik, Jan Sallstrom, Bradford C. Berk, Berislav V. Zlokovic

ABSTRACT

The APOE4-mediated proinflammatory pathway is shown to initiate blood–brain barrier breakdown and resulting neurodegeneration in transgenic mice.

PAGES

512-516

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature11087

DOI

http://dx.doi.org/10.1038/nature11087

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037025366

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22622580


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