Structural basis of ultraviolet-B perception by UVR8 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-02-29

AUTHORS

Di Wu, Qi Hu, Zhen Yan, Wen Chen, Chuangye Yan, Xi Huang, Jing Zhang, Panyu Yang, Haiteng Deng, Jiawei Wang, XingWang Deng, Yigong Shi

ABSTRACT

The Arabidopsis thaliana protein UVR8 is a photoreceptor for ultraviolet-B. Upon ultraviolet-B irradiation, UVR8 undergoes an immediate switch from homodimer to monomer, which triggers a signalling pathway for ultraviolet protection. The mechanism by which UVR8 senses ultraviolet-B remains largely unknown. Here we report the crystal structure of UVR8 at 1.8 Å resolution, revealing a symmetric homodimer of seven-bladed β-propeller that is devoid of any external cofactor as the chromophore. Arginine residues that stabilize the homodimeric interface, principally Arg 286 and Arg 338, make elaborate intramolecular cation-π interactions with surrounding tryptophan amino acids. Two of these tryptophans, Trp 285 and Trp 233, collectively serve as the ultraviolet-B chromophore. Our structural and biochemical analyses identify the molecular mechanism for UVR8-mediated ultraviolet-B perception, in which ultraviolet-B radiation results in destabilization of the intramolecular cation-π interactions, causing disruption of the critical intermolecular hydrogen bonds mediated by Arg 286 and Arg 338 and subsequent dissociation of the UVR8 homodimer. More... »

PAGES

214

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature10931

DOI

http://dx.doi.org/10.1038/nature10931

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015324514

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22388820


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Arabidopsis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Arabidopsis Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cations", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomal Proteins, Non-Histone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Crystallography, X-Ray", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Light Signal Transduction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Conformation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Multimerization", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tryptophan", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ultraviolet Rays", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Tsinghua University", 
          "id": "https://www.grid.ac/institutes/grid.12527.33", 
          "name": [
            "Tsinghua-Peking Center for Life Sciences, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wu", 
        "givenName": "Di", 
        "id": "sg:person.0611313676.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0611313676.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tsinghua University", 
          "id": "https://www.grid.ac/institutes/grid.12527.33", 
          "name": [
            "Tsinghua-Peking Center for Life Sciences, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hu", 
        "givenName": "Qi", 
        "id": "sg:person.01050364011.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050364011.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tsinghua University", 
          "id": "https://www.grid.ac/institutes/grid.12527.33", 
          "name": [
            "Tsinghua-Peking Center for Life Sciences, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yan", 
        "givenName": "Zhen", 
        "id": "sg:person.01062444366.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062444366.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Peking University", 
          "id": "https://www.grid.ac/institutes/grid.11135.37", 
          "name": [
            "College of Life Sciences, Peking University, Beijing 100871, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Wen", 
        "id": "sg:person.0657427076.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657427076.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tsinghua University", 
          "id": "https://www.grid.ac/institutes/grid.12527.33", 
          "name": [
            "State Key Laboratory of Bio-membrane and Membrane Biotechnology, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yan", 
        "givenName": "Chuangye", 
        "id": "sg:person.01274436253.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274436253.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Peking University", 
          "id": "https://www.grid.ac/institutes/grid.11135.37", 
          "name": [
            "College of Life Sciences, Peking University, Beijing 100871, China", 
            "Peking-Yale Joint Center of Plant Molecular Genetics and Agrobiotechnology, State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing 100871, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Huang", 
        "givenName": "Xi", 
        "id": "sg:person.0753001630.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753001630.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tsinghua University", 
          "id": "https://www.grid.ac/institutes/grid.12527.33", 
          "name": [
            "Tsinghua-Peking Center for Life Sciences, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Jing", 
        "id": "sg:person.01307346302.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307346302.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Peking University", 
          "id": "https://www.grid.ac/institutes/grid.11135.37", 
          "name": [
            "College of Life Sciences, Peking University, Beijing 100871, China", 
            "Peking-Yale Joint Center of Plant Molecular Genetics and Agrobiotechnology, State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing 100871, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yang", 
        "givenName": "Panyu", 
        "id": "sg:person.01067230230.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067230230.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tsinghua University", 
          "id": "https://www.grid.ac/institutes/grid.12527.33", 
          "name": [
            "Tsinghua-Peking Center for Life Sciences, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Deng", 
        "givenName": "Haiteng", 
        "id": "sg:person.014402667652.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014402667652.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tsinghua University", 
          "id": "https://www.grid.ac/institutes/grid.12527.33", 
          "name": [
            "State Key Laboratory of Bio-membrane and Membrane Biotechnology, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "Jiawei", 
        "id": "sg:person.011162064574.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011162064574.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Peking University", 
          "id": "https://www.grid.ac/institutes/grid.11135.37", 
          "name": [
            "College of Life Sciences, Peking University, Beijing 100871, China", 
            "Peking-Yale Joint Center of Plant Molecular Genetics and Agrobiotechnology, State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing 100871, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Deng", 
        "givenName": "XingWang", 
        "id": "sg:person.01046222627.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046222627.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tsinghua University", 
          "id": "https://www.grid.ac/institutes/grid.12527.33", 
          "name": [
            "Tsinghua-Peking Center for Life Sciences, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shi", 
        "givenName": "Yigong", 
        "id": "sg:person.012705321277.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012705321277.28"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1105/tpc.107.053330", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000563543"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(95)90220-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001044774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/32204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002348956", 
          "https://doi.org/10.1038/32204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/32204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002348956", 
          "https://doi.org/10.1038/32204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0076-6879(97)76066-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004907170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.107.108456", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005521180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.arplant.58.032806.103951", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006239891"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006975464", 
          "https://doi.org/10.1038/nature04118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006975464", 
          "https://doi.org/10.1038/nature04118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006975464", 
          "https://doi.org/10.1038/nature04118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja025896h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007926071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja025896h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007926071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0070-2153(05)68011-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009303755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.284.5415.760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010010715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.96.17.9459", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012555403"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm728", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012595958", 
          "https://doi.org/10.1038/nrm728"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm728", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012595958", 
          "https://doi.org/10.1038/nrm728"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0021889807021206", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012753217"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0507187102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014434412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0404851101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015204420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08671", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015215827", 
          "https://doi.org/10.1038/nature08671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08671", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015215827", 
          "https://doi.org/10.1038/nature08671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.010475", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018106751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pbio.1000503", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018502424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1097-2765(03)00008-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019432437"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444904019158", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020281098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444902011678", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021532775"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444994003112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025573949"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-arplant-042809-112259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027628625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg2049", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034378320", 
          "https://doi.org/10.1038/nrg2049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/pl00000838", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035096558", 
          "https://doi.org/10.1007/pl00000838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0070-2153(10)91002-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041393563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-arplant-042110-103759", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044954400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tplants.2011.09.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046032823"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja991755c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047741047"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja991755c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047741047"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.051520298", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047833601"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.005041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047865828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444906022116", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048359585"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1360-1385(02)02245-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050836981"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444902016657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051282549"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00048a015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055702048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1199702", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062463071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1200660", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062464348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1218091", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062465935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jn/137.6.1504s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077420310"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2012-02-29", 
    "datePublishedReg": "2012-02-29", 
    "description": "The Arabidopsis thaliana protein UVR8 is a photoreceptor for ultraviolet-B. Upon ultraviolet-B irradiation, UVR8 undergoes an immediate switch from homodimer to monomer, which triggers a signalling pathway for ultraviolet protection. The mechanism by which UVR8 senses ultraviolet-B remains largely unknown. Here we report the crystal structure of UVR8 at 1.8\u2009\u00c5 resolution, revealing a symmetric homodimer of seven-bladed \u03b2-propeller that is devoid of any external cofactor as the chromophore. Arginine residues that stabilize the homodimeric interface, principally Arg\u2009286 and Arg\u2009338, make elaborate intramolecular cation-\u03c0 interactions with surrounding tryptophan amino acids. Two of these tryptophans, Trp\u2009285 and Trp\u2009233, collectively serve as the ultraviolet-B chromophore. Our structural and biochemical analyses identify the molecular mechanism for UVR8-mediated ultraviolet-B perception, in which ultraviolet-B radiation results in destabilization of the intramolecular cation-\u03c0 interactions, causing disruption of the critical intermolecular hydrogen bonds mediated by Arg\u2009286 and Arg\u2009338 and subsequent dissociation of the UVR8 homodimer.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nature10931", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2635317", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7393", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "484"
      }
    ], 
    "name": "Structural basis of ultraviolet-B perception by UVR8", 
    "pagination": "214", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "4903c9db30b3356b53c01e745d4717c52219b595ce0c1cbe72f3c7f4a8278c86"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "22388820"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature10931"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1015324514"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature10931", 
      "https://app.dimensions.ai/details/publication/pub.1015324514"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000435.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/nature10931"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature10931'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature10931'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature10931'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature10931'


 

This table displays all metadata directly associated to this object as RDF triples.

320 TRIPLES      21 PREDICATES      78 URIs      31 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature10931 schema:about N03601450bcdd40bd83bab328d4dd6153
2 N0385fcad89be4591a96937881cfcbbd3
3 N079082d6f5024d41b28811703f6fc9b7
4 N0efb260b90814de3ac84bd539a4b3a4c
5 N5091745c27b24aa792184c2ed1c1d73b
6 N5a9fe25282504910bf2abdc24fc8eae0
7 N69a8d72de1e348c2926fce5a309c2e41
8 Na0b7ef039a664e2195060f35ace2f235
9 Na23541c6690243508e60b6467ade0fd6
10 Naf6abc670af342c5a2eef95bae55d7d4
11 Ne92d0a3b8c9f4dd6be428b93eb3c1fbe
12 anzsrc-for:06
13 anzsrc-for:0601
14 schema:author N6a89f384dee14ca3a2549530d732cdb8
15 schema:citation sg:pub.10.1007/pl00000838
16 sg:pub.10.1038/32204
17 sg:pub.10.1038/nature04118
18 sg:pub.10.1038/nature08671
19 sg:pub.10.1038/nrg2049
20 sg:pub.10.1038/nrm728
21 https://doi.org/10.1016/0092-8674(95)90220-1
22 https://doi.org/10.1016/j.tplants.2011.09.002
23 https://doi.org/10.1016/s0070-2153(05)68011-8
24 https://doi.org/10.1016/s0070-2153(10)91002-8
25 https://doi.org/10.1016/s0076-6879(97)76066-x
26 https://doi.org/10.1016/s1097-2765(03)00008-x
27 https://doi.org/10.1016/s1360-1385(02)02245-8
28 https://doi.org/10.1021/ja00048a015
29 https://doi.org/10.1021/ja025896h
30 https://doi.org/10.1021/ja991755c
31 https://doi.org/10.1073/pnas.0404851101
32 https://doi.org/10.1073/pnas.0507187102
33 https://doi.org/10.1073/pnas.051520298
34 https://doi.org/10.1073/pnas.96.17.9459
35 https://doi.org/10.1093/jn/137.6.1504s
36 https://doi.org/10.1104/pp.005041
37 https://doi.org/10.1104/pp.107.108456
38 https://doi.org/10.1105/tpc.010475
39 https://doi.org/10.1105/tpc.107.053330
40 https://doi.org/10.1107/s0021889807021206
41 https://doi.org/10.1107/s0907444902011678
42 https://doi.org/10.1107/s0907444902016657
43 https://doi.org/10.1107/s0907444904019158
44 https://doi.org/10.1107/s0907444906022116
45 https://doi.org/10.1107/s0907444994003112
46 https://doi.org/10.1126/science.1199702
47 https://doi.org/10.1126/science.1200660
48 https://doi.org/10.1126/science.1218091
49 https://doi.org/10.1126/science.284.5415.760
50 https://doi.org/10.1146/annurev-arplant-042110-103759
51 https://doi.org/10.1146/annurev-arplant-042809-112259
52 https://doi.org/10.1146/annurev.arplant.58.032806.103951
53 https://doi.org/10.1371/journal.pbio.1000503
54 schema:datePublished 2012-02-29
55 schema:datePublishedReg 2012-02-29
56 schema:description The Arabidopsis thaliana protein UVR8 is a photoreceptor for ultraviolet-B. Upon ultraviolet-B irradiation, UVR8 undergoes an immediate switch from homodimer to monomer, which triggers a signalling pathway for ultraviolet protection. The mechanism by which UVR8 senses ultraviolet-B remains largely unknown. Here we report the crystal structure of UVR8 at 1.8 Å resolution, revealing a symmetric homodimer of seven-bladed β-propeller that is devoid of any external cofactor as the chromophore. Arginine residues that stabilize the homodimeric interface, principally Arg 286 and Arg 338, make elaborate intramolecular cation-π interactions with surrounding tryptophan amino acids. Two of these tryptophans, Trp 285 and Trp 233, collectively serve as the ultraviolet-B chromophore. Our structural and biochemical analyses identify the molecular mechanism for UVR8-mediated ultraviolet-B perception, in which ultraviolet-B radiation results in destabilization of the intramolecular cation-π interactions, causing disruption of the critical intermolecular hydrogen bonds mediated by Arg 286 and Arg 338 and subsequent dissociation of the UVR8 homodimer.
57 schema:genre research_article
58 schema:inLanguage en
59 schema:isAccessibleForFree false
60 schema:isPartOf N928f43298e824cedbaf7ba0d429e7004
61 Ne60cde74f30a4e1bb85d13931f5e9bda
62 sg:journal.1018957
63 schema:name Structural basis of ultraviolet-B perception by UVR8
64 schema:pagination 214
65 schema:productId N00b6864c0eef433386f504f21d85c1e1
66 N2551e09a1f634cf497702fdcf7f717de
67 N47d099aed92c456083389b8326fdafb0
68 N75baba71a1eb482582bbefc6273033b6
69 Nc754fdcef5f74aef92f92847d550060e
70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015324514
71 https://doi.org/10.1038/nature10931
72 schema:sdDatePublished 2019-04-11T01:48
73 schema:sdLicense https://scigraph.springernature.com/explorer/license/
74 schema:sdPublisher Nc6e7eae8fadc40d4959038ee3c23191d
75 schema:url https://www.nature.com/articles/nature10931
76 sgo:license sg:explorer/license/
77 sgo:sdDataset articles
78 rdf:type schema:ScholarlyArticle
79 N00b6864c0eef433386f504f21d85c1e1 schema:name dimensions_id
80 schema:value pub.1015324514
81 rdf:type schema:PropertyValue
82 N03601450bcdd40bd83bab328d4dd6153 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Arabidopsis Proteins
84 rdf:type schema:DefinedTerm
85 N0385fcad89be4591a96937881cfcbbd3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Light Signal Transduction
87 rdf:type schema:DefinedTerm
88 N079082d6f5024d41b28811703f6fc9b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Ultraviolet Rays
90 rdf:type schema:DefinedTerm
91 N0efb260b90814de3ac84bd539a4b3a4c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Models, Molecular
93 rdf:type schema:DefinedTerm
94 N14b9a72caa0147d2b8b0b55a507cc44c rdf:first sg:person.01046222627.29
95 rdf:rest Nca1be2808db7490a9d71516e361d3e19
96 N2551e09a1f634cf497702fdcf7f717de schema:name pubmed_id
97 schema:value 22388820
98 rdf:type schema:PropertyValue
99 N2f09c4f8d5b948caa975edf4caa681d7 rdf:first sg:person.01067230230.48
100 rdf:rest Nea7e4bcd1e1e42828ed90c31b7953f86
101 N47d099aed92c456083389b8326fdafb0 schema:name nlm_unique_id
102 schema:value 0410462
103 rdf:type schema:PropertyValue
104 N5091745c27b24aa792184c2ed1c1d73b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Protein Multimerization
106 rdf:type schema:DefinedTerm
107 N5305813a9e0649ddb773af0690e768fd rdf:first sg:person.01274436253.23
108 rdf:rest N6e7aad0b9e25486f977eec6df7cefcec
109 N5375e9e3dce84ae099de07cfa920b863 rdf:first sg:person.01307346302.11
110 rdf:rest N2f09c4f8d5b948caa975edf4caa681d7
111 N5a9fe25282504910bf2abdc24fc8eae0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Cations
113 rdf:type schema:DefinedTerm
114 N69a8d72de1e348c2926fce5a309c2e41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Tryptophan
116 rdf:type schema:DefinedTerm
117 N6a89f384dee14ca3a2549530d732cdb8 rdf:first sg:person.0611313676.02
118 rdf:rest Na244311972494cdf8a7fb2727f108aef
119 N6e7aad0b9e25486f977eec6df7cefcec rdf:first sg:person.0753001630.70
120 rdf:rest N5375e9e3dce84ae099de07cfa920b863
121 N73b347fd341e4628855132123b689cb9 rdf:first sg:person.011162064574.53
122 rdf:rest N14b9a72caa0147d2b8b0b55a507cc44c
123 N75baba71a1eb482582bbefc6273033b6 schema:name doi
124 schema:value 10.1038/nature10931
125 rdf:type schema:PropertyValue
126 N928f43298e824cedbaf7ba0d429e7004 schema:volumeNumber 484
127 rdf:type schema:PublicationVolume
128 N932f3fc79dda4ce5a142d6ac5d51e77a rdf:first sg:person.0657427076.27
129 rdf:rest N5305813a9e0649ddb773af0690e768fd
130 Na0b7ef039a664e2195060f35ace2f235 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Arabidopsis
132 rdf:type schema:DefinedTerm
133 Na23541c6690243508e60b6467ade0fd6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Chromosomal Proteins, Non-Histone
135 rdf:type schema:DefinedTerm
136 Na244311972494cdf8a7fb2727f108aef rdf:first sg:person.01050364011.51
137 rdf:rest Nad101beaaba84bc1a32c6038fa17cd54
138 Nad101beaaba84bc1a32c6038fa17cd54 rdf:first sg:person.01062444366.20
139 rdf:rest N932f3fc79dda4ce5a142d6ac5d51e77a
140 Naf6abc670af342c5a2eef95bae55d7d4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Protein Conformation
142 rdf:type schema:DefinedTerm
143 Nc6e7eae8fadc40d4959038ee3c23191d schema:name Springer Nature - SN SciGraph project
144 rdf:type schema:Organization
145 Nc754fdcef5f74aef92f92847d550060e schema:name readcube_id
146 schema:value 4903c9db30b3356b53c01e745d4717c52219b595ce0c1cbe72f3c7f4a8278c86
147 rdf:type schema:PropertyValue
148 Nca1be2808db7490a9d71516e361d3e19 rdf:first sg:person.012705321277.28
149 rdf:rest rdf:nil
150 Ne60cde74f30a4e1bb85d13931f5e9bda schema:issueNumber 7393
151 rdf:type schema:PublicationIssue
152 Ne92d0a3b8c9f4dd6be428b93eb3c1fbe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Crystallography, X-Ray
154 rdf:type schema:DefinedTerm
155 Nea7e4bcd1e1e42828ed90c31b7953f86 rdf:first sg:person.014402667652.75
156 rdf:rest N73b347fd341e4628855132123b689cb9
157 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
158 schema:name Biological Sciences
159 rdf:type schema:DefinedTerm
160 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
161 schema:name Biochemistry and Cell Biology
162 rdf:type schema:DefinedTerm
163 sg:grant.2635317 http://pending.schema.org/fundedItem sg:pub.10.1038/nature10931
164 rdf:type schema:MonetaryGrant
165 sg:journal.1018957 schema:issn 0090-0028
166 1476-4687
167 schema:name Nature
168 rdf:type schema:Periodical
169 sg:person.01046222627.29 schema:affiliation https://www.grid.ac/institutes/grid.11135.37
170 schema:familyName Deng
171 schema:givenName XingWang
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046222627.29
173 rdf:type schema:Person
174 sg:person.01050364011.51 schema:affiliation https://www.grid.ac/institutes/grid.12527.33
175 schema:familyName Hu
176 schema:givenName Qi
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050364011.51
178 rdf:type schema:Person
179 sg:person.01062444366.20 schema:affiliation https://www.grid.ac/institutes/grid.12527.33
180 schema:familyName Yan
181 schema:givenName Zhen
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062444366.20
183 rdf:type schema:Person
184 sg:person.01067230230.48 schema:affiliation https://www.grid.ac/institutes/grid.11135.37
185 schema:familyName Yang
186 schema:givenName Panyu
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067230230.48
188 rdf:type schema:Person
189 sg:person.011162064574.53 schema:affiliation https://www.grid.ac/institutes/grid.12527.33
190 schema:familyName Wang
191 schema:givenName Jiawei
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011162064574.53
193 rdf:type schema:Person
194 sg:person.012705321277.28 schema:affiliation https://www.grid.ac/institutes/grid.12527.33
195 schema:familyName Shi
196 schema:givenName Yigong
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012705321277.28
198 rdf:type schema:Person
199 sg:person.01274436253.23 schema:affiliation https://www.grid.ac/institutes/grid.12527.33
200 schema:familyName Yan
201 schema:givenName Chuangye
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274436253.23
203 rdf:type schema:Person
204 sg:person.01307346302.11 schema:affiliation https://www.grid.ac/institutes/grid.12527.33
205 schema:familyName Zhang
206 schema:givenName Jing
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307346302.11
208 rdf:type schema:Person
209 sg:person.014402667652.75 schema:affiliation https://www.grid.ac/institutes/grid.12527.33
210 schema:familyName Deng
211 schema:givenName Haiteng
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014402667652.75
213 rdf:type schema:Person
214 sg:person.0611313676.02 schema:affiliation https://www.grid.ac/institutes/grid.12527.33
215 schema:familyName Wu
216 schema:givenName Di
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0611313676.02
218 rdf:type schema:Person
219 sg:person.0657427076.27 schema:affiliation https://www.grid.ac/institutes/grid.11135.37
220 schema:familyName Chen
221 schema:givenName Wen
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657427076.27
223 rdf:type schema:Person
224 sg:person.0753001630.70 schema:affiliation https://www.grid.ac/institutes/grid.11135.37
225 schema:familyName Huang
226 schema:givenName Xi
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753001630.70
228 rdf:type schema:Person
229 sg:pub.10.1007/pl00000838 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035096558
230 https://doi.org/10.1007/pl00000838
231 rdf:type schema:CreativeWork
232 sg:pub.10.1038/32204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002348956
233 https://doi.org/10.1038/32204
234 rdf:type schema:CreativeWork
235 sg:pub.10.1038/nature04118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006975464
236 https://doi.org/10.1038/nature04118
237 rdf:type schema:CreativeWork
238 sg:pub.10.1038/nature08671 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015215827
239 https://doi.org/10.1038/nature08671
240 rdf:type schema:CreativeWork
241 sg:pub.10.1038/nrg2049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034378320
242 https://doi.org/10.1038/nrg2049
243 rdf:type schema:CreativeWork
244 sg:pub.10.1038/nrm728 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012595958
245 https://doi.org/10.1038/nrm728
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1016/0092-8674(95)90220-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001044774
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1016/j.tplants.2011.09.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046032823
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/s0070-2153(05)68011-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009303755
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/s0070-2153(10)91002-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041393563
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/s0076-6879(97)76066-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004907170
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/s1097-2765(03)00008-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019432437
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/s1360-1385(02)02245-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050836981
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1021/ja00048a015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055702048
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1021/ja025896h schema:sameAs https://app.dimensions.ai/details/publication/pub.1007926071
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1021/ja991755c schema:sameAs https://app.dimensions.ai/details/publication/pub.1047741047
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1073/pnas.0404851101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015204420
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1073/pnas.0507187102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014434412
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1073/pnas.051520298 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047833601
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1073/pnas.96.17.9459 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012555403
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1093/jn/137.6.1504s schema:sameAs https://app.dimensions.ai/details/publication/pub.1077420310
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1104/pp.005041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047865828
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1104/pp.107.108456 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005521180
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1105/tpc.010475 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018106751
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1105/tpc.107.053330 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000563543
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1107/s0021889807021206 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012753217
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1107/s0907444902011678 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021532775
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1107/s0907444902016657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051282549
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1107/s0907444904019158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020281098
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1107/s0907444906022116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048359585
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1107/s0907444994003112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025573949
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1126/science.1199702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062463071
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1126/science.1200660 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062464348
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1126/science.1218091 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062465935
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1126/science.284.5415.760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010010715
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1146/annurev-arplant-042110-103759 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044954400
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1146/annurev-arplant-042809-112259 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027628625
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1146/annurev.arplant.58.032806.103951 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006239891
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1371/journal.pbio.1000503 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018502424
312 rdf:type schema:CreativeWork
313 https://www.grid.ac/institutes/grid.11135.37 schema:alternateName Peking University
314 schema:name College of Life Sciences, Peking University, Beijing 100871, China
315 Peking-Yale Joint Center of Plant Molecular Genetics and Agrobiotechnology, State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing 100871, China
316 rdf:type schema:Organization
317 https://www.grid.ac/institutes/grid.12527.33 schema:alternateName Tsinghua University
318 schema:name State Key Laboratory of Bio-membrane and Membrane Biotechnology, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China
319 Tsinghua-Peking Center for Life Sciences, Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China
320 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...