Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-03-18

AUTHORS

Rui Benedito, Susana F. Rocha, Marina Woeste, Martin Zamykal, Freddy Radtke, Oriol Casanovas, Antonio Duarte, Bronislaw Pytowski, Ralf H. Adams

ABSTRACT

DLL4–Notch signalling suppresses endothelial sprouting and angiogenic growth through crosstalk with the vascular endothelial growth factor (VEGF) pathway; VEGF receptor 2 has been thought to have a crucial role in this crosstalk, but now VEGF receptor 3 is shown to be the more important modulator.

PAGES

110-114

Journal

TITLE

Nature

ISSUE

7392

VOLUME

484

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature10908

DOI

http://dx.doi.org/10.1038/nature10908

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029404187

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22426001


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