Clonal evolution in cancer View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-01

AUTHORS

Mel Greaves, Carlo C. Maley

ABSTRACT

Cancers evolve by a reiterative process of clonal expansion, genetic diversification and clonal selection within the adaptive landscapes of tissue ecosystems. The dynamics are complex, with highly variable patterns of genetic diversity and resulting clonal architecture. Therapeutic intervention may destroy cancer clones and erode their habitats, but it can also inadvertently provide a potent selective pressure for the expansion of resistant variants. The inherently Darwinian character of cancer is the primary reason for this therapeutic failure, but it may also hold the key to more effective control. More... »

PAGES

306

References to SciGraph publications

  • 2011-03. Cancer genomics: from discovery science to personalized medicine in NATURE MEDICINE
  • 2006-07. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer in NATURE GENETICS
  • 2009-10. Shifting paradigms: the seeds of oncogene addiction in NATURE MEDICINE
  • 2010-04-15. Genome remodelling in a basal-like breast cancer metastasis and xenograft in NATURE
  • 2006-04. Genetic clonal diversity predicts progression to esophageal adenocarcinoma in NATURE GENETICS
  • 2011-03. Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression in NATURE MEDICINE
  • 2005-11. Radiation and the microenvironment – tumorigenesis and therapy in NATURE REVIEWS CANCER
  • 2009-04. Parallel progression of primary tumours and metastases in NATURE REVIEWS CANCER
  • 2009-04. Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution in ONCOGENE
  • 1992-02. Clonal expansion of p53 mutant cells is associated with brain tumour progression in NATURE
  • 2008-03. Complex patterns of ETS gene alteration arise during cancer development in the human prostate in ONCOGENE
  • 2011-06. Human cancers express mutator phenotypes: origin, consequences and targeting in NATURE REVIEWS CANCER
  • 2007-11. Models, mechanisms and clinical evidence for cancer dormancy in NATURE REVIEWS CANCER
  • 1975-05. Mutation selection and the natural history of cancer in NATURE
  • 2006-08. Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9 in NATURE
  • 2005-03. Testicular germ-cell tumours in a broader perspective in NATURE REVIEWS CANCER
  • 2008-01. A microenvironmental model of carcinogenesis in NATURE REVIEWS CANCER
  • 2011-09. Cancer stem cells renew their impact in NATURE MEDICINE
  • 2011-04. Tumour evolution inferred by single-cell sequencing in NATURE
  • 2001-11. Stem cells, cancer, and cancer stem cells in NATURE
  • 2010-12. Drug discovery: How melanomas bypass new therapy in NATURE
  • 1993-11. Punctuated equilibrium comes of age in NATURE
  • 2011-05. BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition in NATURE
  • 2011-01. Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells in NATURE
  • 2008-12. Efficient tumour formation by single human melanoma cells in NATURE
  • 2010-10-28. Distant metastasis occurs late during the genetic evolution of pancreatic cancer in NATURE
  • 2008-05-08. Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors in NATURE
  • 2010-02-18. Signatures of mutation and selection in the cancer genome in NATURE
  • 2007-11. Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region in NATURE BIOTECHNOLOGY
  • 2006-12. Cancer as an evolutionary and ecological process in NATURE REVIEWS CANCER
  • 2006-07. Tumour microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer in NATURE REVIEWS CANCER
  • 2011-01. Genetic variegation of clonal architecture and propagating cells in leukaemia in NATURE
  • 2010-02. Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis in NATURE REVIEWS CANCER
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    http://scigraph.springernature.com/pub.10.1038/nature10762

    DOI

    http://dx.doi.org/10.1038/nature10762

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1053038796

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22258609


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