Charting a course for genomic medicine from base pairs to bedside View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-02-09

AUTHORS

Eric D. Green, Mark S. Guyer, Teri A. Manolio, Jane L. Peterson

ABSTRACT

Human genomics comes of ageTo mark the tenth anniversary of the publication reporting a draft sequence of the human genome by the Human Genome Project, this issue of Nature presents three major papers about human genomics. Eric Lander, present at the birth of the Human Genome Project, looks back at what has been achieved in genomics and speculates on future prospects. Elaine Mardis discusses the DNA sequencing technologies that have catalysed the rapid genomic advances over the past ten years. And Eric Green, Mark Guyer and others from the US National Human Genome Research Institute provide a vision for the future of genomic medicine. More... »

PAGES

204-213

References to SciGraph publications

  • 2001-02-15. Initial sequencing and analysis of the human genome in NATURE
  • 2010-04. International network of cancer genome projects in NATURE
  • 2009-12-08. Sequencing technologies — the next generation in NATURE REVIEWS GENETICS
  • 2009-10. Finding the missing heritability of complex diseases in NATURE
  • 2010-07-13. Annotating non-coding regions of the genome in NATURE REVIEWS GENETICS
  • 2008-10-05. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells in NATURE
  • 2003-08-14. Difficulty in losing weight by behavioral intervention for women with Trp64Arg polymorphism of the β3-adrenergic receptor gene in INTERNATIONAL JOURNAL OF OBESITY
  • 2004-09. The Knockout Mouse Project in NATURE GENETICS
  • 2004-11-17. Targeted cancer therapy in NATURE
  • 2010-05-05. The case for cloud computing in genome informatics in GENOME BIOLOGY
  • 2008-11. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome in NATURE
  • 2010-10-13. Epigenomics reveals a functional genome anatomy and a new approach to common disease in NATURE BIOTECHNOLOGY
  • 2009-05-22. The A's, G's, C's, and T's of health disparities in BMC MEDICAL GENOMICS
  • 2010-10-13. The NIH Roadmap Epigenomics Mapping Consortium in NATURE BIOTECHNOLOGY
  • 2003-04-14. A vision for the future of genomics research in NATURE
  • 2010-09. Integrating common and rare genetic variation in diverse human populations in NATURE
  • 2007-04-15. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis in NATURE GENETICS
  • 2010-03. A human gut microbial gene catalogue established by metagenomic sequencing in NATURE
  • 2010-10-13. Epigenetic modifications and human disease in NATURE BIOTECHNOLOGY
  • 2010-10-27. A map of human genome variation from population-scale sequencing in NATURE
  • 2007-06. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project in NATURE
  • 2010-09-17. Advances in understanding cancer genomes through second-generation sequencing in NATURE REVIEWS GENETICS
  • 2007-10. The NCBI dbGaP database of genotypes and phenotypes in NATURE GENETICS
  • 2009-09-09. Prepublication data sharing in NATURE
  • 2008-09-14. MYH9 is associated with nondiabetic end-stage renal disease in African Americans in NATURE GENETICS
  • 2010-06-13. Microfluidics in macro-biomolecules analysis: macro inside in a nano world in ANALYTICAL AND BIOANALYTICAL CHEMISTRY
  • 2010-02. Signatures of mutation and selection in the cancer genome in NATURE
  • 2004-05. The case for a US prospective cohort study of genes and environment in NATURE
  • 2008-09-04. Comprehensive genomic characterization defines human glioblastoma genes and core pathways in NATURE
  • 2011-02-09. A decade’s perspective on DNA sequencing technology in NATURE
  • 2004-10. Finishing the euchromatic sequence of the human genome in NATURE
  • 2011-02-09. Initial impact of the sequencing of the human genome in NATURE
  • 2008-02. Research ethics and the challenge of whole-genome sequencing in NATURE REVIEWS GENETICS
  • 2010-05-05. Direct sequencing of the human microbiome readily reveals community differences in GENOME BIOLOGY
  • 2006-11-18. The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen in BREAST CANCER RESEARCH AND TREATMENT
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature09764

    DOI

    http://dx.doi.org/10.1038/nature09764

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1037658930

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/21307933


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Base Pairing", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genetic Counseling", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genetic Predisposition to Disease", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genetics, Medical", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genome, Human", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genomics", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Human Genome Project", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "familyName": "Green", 
            "givenName": "Eric D.", 
            "id": "sg:person.012674020457.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012674020457.18"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Guyer", 
            "givenName": "Mark S.", 
            "id": "sg:person.014377323407.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014377323407.88"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Manolio", 
            "givenName": "Teri A.", 
            "id": "sg:person.01014127221.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014127221.11"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Peterson", 
            "givenName": "Jane L.", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/nature09792", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018122872", 
              "https://doi.org/10.1038/nature09792"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2302", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029864299", 
              "https://doi.org/10.1038/nrg2302"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature09796", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049651011", 
              "https://doi.org/10.1038/nature09796"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng2032", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003006579", 
              "https://doi.org/10.1038/ng2032"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.ijo.0802375", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028425353", 
              "https://doi.org/10.1038/sj.ijo.0802375"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1755-8794-2-29", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023648436", 
              "https://doi.org/10.1186/1755-8794-2-29"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature09298", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052674054", 
              "https://doi.org/10.1038/nature09298"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature07485", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034796960", 
              "https://doi.org/10.1038/nature07485"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08821", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050498034", 
              "https://doi.org/10.1038/nature08821"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03095", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010000533", 
              "https://doi.org/10.1038/nature03095"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature07416", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001354010", 
              "https://doi.org/10.1038/nature07416"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2626", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023911485", 
              "https://doi.org/10.1038/nrg2626"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00216-010-3857-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004239643", 
              "https://doi.org/10.1007/s00216-010-3857-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1010-1045", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048301228", 
              "https://doi.org/10.1038/nbt1010-1045"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2814", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025132392", 
              "https://doi.org/10.1038/nrg2814"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/461168a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035889273", 
              "https://doi.org/10.1038/461168a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature09534", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010608717", 
              "https://doi.org/10.1038/nature09534"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1010-1049", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045535323", 
              "https://doi.org/10.1038/nbt1010-1049"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/gb-2010-11-5-207", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011746478", 
              "https://doi.org/10.1186/gb-2010-11-5-207"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature07385", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039570773", 
              "https://doi.org/10.1038/nature07385"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08987", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010562574", 
              "https://doi.org/10.1038/nature08987"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2841", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017741162", 
              "https://doi.org/10.1038/nrg2841"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng0904-921", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031431102", 
              "https://doi.org/10.1038/ng0904-921"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.232", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008005765", 
              "https://doi.org/10.1038/ng.232"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature02628", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034424510", 
              "https://doi.org/10.1038/nature02628"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1007-1181", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033997263", 
              "https://doi.org/10.1038/ng1007-1181"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08768", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002735811", 
              "https://doi.org/10.1038/nature08768"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature05874", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005913886", 
              "https://doi.org/10.1038/nature05874"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35057062", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042854081", 
              "https://doi.org/10.1038/35057062"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08494", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005147626", 
              "https://doi.org/10.1038/nature08494"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01626", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012394158", 
              "https://doi.org/10.1038/nature01626"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1685", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011479792", 
              "https://doi.org/10.1038/nbt.1685"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10549-006-9428-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007965097", 
              "https://doi.org/10.1007/s10549-006-9428-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/gb-2010-11-5-210", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042123396", 
              "https://doi.org/10.1186/gb-2010-11-5-210"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013534924", 
              "https://doi.org/10.1038/nature03001"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2011-02-09", 
        "datePublishedReg": "2011-02-09", 
        "description": "Human genomics comes of ageTo mark the tenth anniversary of the publication reporting a draft sequence of the human genome by the Human Genome Project, this issue of Nature presents three major papers about human genomics. Eric Lander, present at the birth of the Human Genome Project, looks back at what has been achieved in genomics and speculates on future prospects. Elaine Mardis discusses the DNA sequencing technologies that have catalysed the rapid genomic advances over the past ten years. And Eric Green, Mark Guyer and others from the US National Human Genome Research Institute provide a vision for the future of genomic medicine.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/nature09764", 
        "inLanguage": "en", 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1018957", 
            "issn": [
              "0028-0836", 
              "1476-4687"
            ], 
            "name": "Nature", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "7333", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "470"
          }
        ], 
        "keywords": [
          "Human Genome Project", 
          "Genome Project", 
          "human genomics", 
          "DNA sequencing technologies", 
          "National Human Genome Research Institute", 
          "draft sequence", 
          "human genome", 
          "genomic medicine", 
          "sequencing technologies", 
          "genomic advances", 
          "genomics", 
          "base pairs", 
          "Eric Lander", 
          "genome", 
          "issue of Nature", 
          "sequence", 
          "future prospects", 
          "speculates", 
          "pairs", 
          "advances", 
          "Research Institute", 
          "major papers", 
          "medicine", 
          "green", 
          "nature", 
          "prospects", 
          "future", 
          "birth", 
          "years", 
          "technology", 
          "project", 
          "course", 
          "publications", 
          "Institute", 
          "tenth anniversary", 
          "anniversary", 
          "issues", 
          "lander", 
          "vision", 
          "Guyer", 
          "paper"
        ], 
        "name": "Charting a course for genomic medicine from base pairs to bedside", 
        "pagination": "204-213", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1037658930"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nature09764"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "21307933"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nature09764", 
          "https://app.dimensions.ai/details/publication/pub.1037658930"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-05-10T10:02", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_553.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/nature09764"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature09764'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature09764'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature09764'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature09764'


     

    This table displays all metadata directly associated to this object as RDF triples.

    288 TRIPLES      22 PREDICATES      110 URIs      67 LITERALS      15 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nature09764 schema:about N05fe861ecc7b4b0282f005763a8d5004
    2 N6ff65aa65c9740cc8aa95b62182423ad
    3 N8ada0af0daa34f4e90712a59531e609a
    4 N8af601c8f4174e6f8af6e0abbed48598
    5 N9684a94190d74a4580b240cf6dac928a
    6 Necc42186992c4877a9ec10001403495d
    7 Nefd30b64c0ab4cffbda703b9f81009e5
    8 Nfa05d5f438a54eaa865741b1495f1b3d
    9 anzsrc-for:06
    10 anzsrc-for:0604
    11 schema:author N22356541c7944d739ec2a61f2338388b
    12 schema:citation sg:pub.10.1007/s00216-010-3857-7
    13 sg:pub.10.1007/s10549-006-9428-0
    14 sg:pub.10.1038/35057062
    15 sg:pub.10.1038/461168a
    16 sg:pub.10.1038/nature01626
    17 sg:pub.10.1038/nature02628
    18 sg:pub.10.1038/nature03001
    19 sg:pub.10.1038/nature03095
    20 sg:pub.10.1038/nature05874
    21 sg:pub.10.1038/nature07385
    22 sg:pub.10.1038/nature07416
    23 sg:pub.10.1038/nature07485
    24 sg:pub.10.1038/nature08494
    25 sg:pub.10.1038/nature08768
    26 sg:pub.10.1038/nature08821
    27 sg:pub.10.1038/nature08987
    28 sg:pub.10.1038/nature09298
    29 sg:pub.10.1038/nature09534
    30 sg:pub.10.1038/nature09792
    31 sg:pub.10.1038/nature09796
    32 sg:pub.10.1038/nbt.1685
    33 sg:pub.10.1038/nbt1010-1045
    34 sg:pub.10.1038/nbt1010-1049
    35 sg:pub.10.1038/ng.232
    36 sg:pub.10.1038/ng0904-921
    37 sg:pub.10.1038/ng1007-1181
    38 sg:pub.10.1038/ng2032
    39 sg:pub.10.1038/nrg2302
    40 sg:pub.10.1038/nrg2626
    41 sg:pub.10.1038/nrg2814
    42 sg:pub.10.1038/nrg2841
    43 sg:pub.10.1038/sj.ijo.0802375
    44 sg:pub.10.1186/1755-8794-2-29
    45 sg:pub.10.1186/gb-2010-11-5-207
    46 sg:pub.10.1186/gb-2010-11-5-210
    47 schema:datePublished 2011-02-09
    48 schema:datePublishedReg 2011-02-09
    49 schema:description Human genomics comes of ageTo mark the tenth anniversary of the publication reporting a draft sequence of the human genome by the Human Genome Project, this issue of Nature presents three major papers about human genomics. Eric Lander, present at the birth of the Human Genome Project, looks back at what has been achieved in genomics and speculates on future prospects. Elaine Mardis discusses the DNA sequencing technologies that have catalysed the rapid genomic advances over the past ten years. And Eric Green, Mark Guyer and others from the US National Human Genome Research Institute provide a vision for the future of genomic medicine.
    50 schema:genre article
    51 schema:inLanguage en
    52 schema:isAccessibleForFree true
    53 schema:isPartOf N09741dac235c4f4bbb676bdd9432b3d8
    54 Nb795905e05ff4a45a73cf0413cab52b1
    55 sg:journal.1018957
    56 schema:keywords DNA sequencing technologies
    57 Eric Lander
    58 Genome Project
    59 Guyer
    60 Human Genome Project
    61 Institute
    62 National Human Genome Research Institute
    63 Research Institute
    64 advances
    65 anniversary
    66 base pairs
    67 birth
    68 course
    69 draft sequence
    70 future
    71 future prospects
    72 genome
    73 genomic advances
    74 genomic medicine
    75 genomics
    76 green
    77 human genome
    78 human genomics
    79 issue of Nature
    80 issues
    81 lander
    82 major papers
    83 medicine
    84 nature
    85 pairs
    86 paper
    87 project
    88 prospects
    89 publications
    90 sequence
    91 sequencing technologies
    92 speculates
    93 technology
    94 tenth anniversary
    95 vision
    96 years
    97 schema:name Charting a course for genomic medicine from base pairs to bedside
    98 schema:pagination 204-213
    99 schema:productId N07debf1338dc47fd98385210e97b6705
    100 N30991fee59634b3fb21f4dac0d11481f
    101 Ne00c3af15dc245aea648907703c2735e
    102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037658930
    103 https://doi.org/10.1038/nature09764
    104 schema:sdDatePublished 2022-05-10T10:02
    105 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    106 schema:sdPublisher Nb06f767b3b924fd4869fde1250a190e9
    107 schema:url https://doi.org/10.1038/nature09764
    108 sgo:license sg:explorer/license/
    109 sgo:sdDataset articles
    110 rdf:type schema:ScholarlyArticle
    111 N05fe861ecc7b4b0282f005763a8d5004 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    112 schema:name Genomics
    113 rdf:type schema:DefinedTerm
    114 N07debf1338dc47fd98385210e97b6705 schema:name dimensions_id
    115 schema:value pub.1037658930
    116 rdf:type schema:PropertyValue
    117 N09741dac235c4f4bbb676bdd9432b3d8 schema:issueNumber 7333
    118 rdf:type schema:PublicationIssue
    119 N145e2d34cde24682bd837e5a06b2b836 schema:familyName Peterson
    120 schema:givenName Jane L.
    121 rdf:type schema:Person
    122 N1e02178fe31042be8acb615900745f22 rdf:first sg:person.01014127221.11
    123 rdf:rest N347c4287f0634f69b61eb18087f4c4f6
    124 N22356541c7944d739ec2a61f2338388b rdf:first sg:person.012674020457.18
    125 rdf:rest Ncf3f0ddb81c64b2c9e62f735734c8698
    126 N30991fee59634b3fb21f4dac0d11481f schema:name pubmed_id
    127 schema:value 21307933
    128 rdf:type schema:PropertyValue
    129 N347c4287f0634f69b61eb18087f4c4f6 rdf:first N145e2d34cde24682bd837e5a06b2b836
    130 rdf:rest rdf:nil
    131 N6ff65aa65c9740cc8aa95b62182423ad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    132 schema:name Genetics, Medical
    133 rdf:type schema:DefinedTerm
    134 N8ada0af0daa34f4e90712a59531e609a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    135 schema:name Genome, Human
    136 rdf:type schema:DefinedTerm
    137 N8af601c8f4174e6f8af6e0abbed48598 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    138 schema:name Human Genome Project
    139 rdf:type schema:DefinedTerm
    140 N9684a94190d74a4580b240cf6dac928a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    141 schema:name Base Pairing
    142 rdf:type schema:DefinedTerm
    143 Nb06f767b3b924fd4869fde1250a190e9 schema:name Springer Nature - SN SciGraph project
    144 rdf:type schema:Organization
    145 Nb795905e05ff4a45a73cf0413cab52b1 schema:volumeNumber 470
    146 rdf:type schema:PublicationVolume
    147 Ncf3f0ddb81c64b2c9e62f735734c8698 rdf:first sg:person.014377323407.88
    148 rdf:rest N1e02178fe31042be8acb615900745f22
    149 Ne00c3af15dc245aea648907703c2735e schema:name doi
    150 schema:value 10.1038/nature09764
    151 rdf:type schema:PropertyValue
    152 Necc42186992c4877a9ec10001403495d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    153 schema:name Genetic Counseling
    154 rdf:type schema:DefinedTerm
    155 Nefd30b64c0ab4cffbda703b9f81009e5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    156 schema:name Genetic Predisposition to Disease
    157 rdf:type schema:DefinedTerm
    158 Nfa05d5f438a54eaa865741b1495f1b3d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    159 schema:name Humans
    160 rdf:type schema:DefinedTerm
    161 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    162 schema:name Biological Sciences
    163 rdf:type schema:DefinedTerm
    164 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    165 schema:name Genetics
    166 rdf:type schema:DefinedTerm
    167 sg:journal.1018957 schema:issn 0028-0836
    168 1476-4687
    169 schema:name Nature
    170 schema:publisher Springer Nature
    171 rdf:type schema:Periodical
    172 sg:person.01014127221.11 schema:familyName Manolio
    173 schema:givenName Teri A.
    174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014127221.11
    175 rdf:type schema:Person
    176 sg:person.012674020457.18 schema:familyName Green
    177 schema:givenName Eric D.
    178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012674020457.18
    179 rdf:type schema:Person
    180 sg:person.014377323407.88 schema:familyName Guyer
    181 schema:givenName Mark S.
    182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014377323407.88
    183 rdf:type schema:Person
    184 sg:pub.10.1007/s00216-010-3857-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004239643
    185 https://doi.org/10.1007/s00216-010-3857-7
    186 rdf:type schema:CreativeWork
    187 sg:pub.10.1007/s10549-006-9428-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007965097
    188 https://doi.org/10.1007/s10549-006-9428-0
    189 rdf:type schema:CreativeWork
    190 sg:pub.10.1038/35057062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042854081
    191 https://doi.org/10.1038/35057062
    192 rdf:type schema:CreativeWork
    193 sg:pub.10.1038/461168a schema:sameAs https://app.dimensions.ai/details/publication/pub.1035889273
    194 https://doi.org/10.1038/461168a
    195 rdf:type schema:CreativeWork
    196 sg:pub.10.1038/nature01626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012394158
    197 https://doi.org/10.1038/nature01626
    198 rdf:type schema:CreativeWork
    199 sg:pub.10.1038/nature02628 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034424510
    200 https://doi.org/10.1038/nature02628
    201 rdf:type schema:CreativeWork
    202 sg:pub.10.1038/nature03001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013534924
    203 https://doi.org/10.1038/nature03001
    204 rdf:type schema:CreativeWork
    205 sg:pub.10.1038/nature03095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010000533
    206 https://doi.org/10.1038/nature03095
    207 rdf:type schema:CreativeWork
    208 sg:pub.10.1038/nature05874 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005913886
    209 https://doi.org/10.1038/nature05874
    210 rdf:type schema:CreativeWork
    211 sg:pub.10.1038/nature07385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039570773
    212 https://doi.org/10.1038/nature07385
    213 rdf:type schema:CreativeWork
    214 sg:pub.10.1038/nature07416 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001354010
    215 https://doi.org/10.1038/nature07416
    216 rdf:type schema:CreativeWork
    217 sg:pub.10.1038/nature07485 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034796960
    218 https://doi.org/10.1038/nature07485
    219 rdf:type schema:CreativeWork
    220 sg:pub.10.1038/nature08494 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005147626
    221 https://doi.org/10.1038/nature08494
    222 rdf:type schema:CreativeWork
    223 sg:pub.10.1038/nature08768 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002735811
    224 https://doi.org/10.1038/nature08768
    225 rdf:type schema:CreativeWork
    226 sg:pub.10.1038/nature08821 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050498034
    227 https://doi.org/10.1038/nature08821
    228 rdf:type schema:CreativeWork
    229 sg:pub.10.1038/nature08987 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010562574
    230 https://doi.org/10.1038/nature08987
    231 rdf:type schema:CreativeWork
    232 sg:pub.10.1038/nature09298 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052674054
    233 https://doi.org/10.1038/nature09298
    234 rdf:type schema:CreativeWork
    235 sg:pub.10.1038/nature09534 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010608717
    236 https://doi.org/10.1038/nature09534
    237 rdf:type schema:CreativeWork
    238 sg:pub.10.1038/nature09792 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018122872
    239 https://doi.org/10.1038/nature09792
    240 rdf:type schema:CreativeWork
    241 sg:pub.10.1038/nature09796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049651011
    242 https://doi.org/10.1038/nature09796
    243 rdf:type schema:CreativeWork
    244 sg:pub.10.1038/nbt.1685 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011479792
    245 https://doi.org/10.1038/nbt.1685
    246 rdf:type schema:CreativeWork
    247 sg:pub.10.1038/nbt1010-1045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048301228
    248 https://doi.org/10.1038/nbt1010-1045
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1038/nbt1010-1049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045535323
    251 https://doi.org/10.1038/nbt1010-1049
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1038/ng.232 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008005765
    254 https://doi.org/10.1038/ng.232
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1038/ng0904-921 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031431102
    257 https://doi.org/10.1038/ng0904-921
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1038/ng1007-1181 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033997263
    260 https://doi.org/10.1038/ng1007-1181
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1038/ng2032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003006579
    263 https://doi.org/10.1038/ng2032
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1038/nrg2302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029864299
    266 https://doi.org/10.1038/nrg2302
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1038/nrg2626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023911485
    269 https://doi.org/10.1038/nrg2626
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1038/nrg2814 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025132392
    272 https://doi.org/10.1038/nrg2814
    273 rdf:type schema:CreativeWork
    274 sg:pub.10.1038/nrg2841 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017741162
    275 https://doi.org/10.1038/nrg2841
    276 rdf:type schema:CreativeWork
    277 sg:pub.10.1038/sj.ijo.0802375 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028425353
    278 https://doi.org/10.1038/sj.ijo.0802375
    279 rdf:type schema:CreativeWork
    280 sg:pub.10.1186/1755-8794-2-29 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023648436
    281 https://doi.org/10.1186/1755-8794-2-29
    282 rdf:type schema:CreativeWork
    283 sg:pub.10.1186/gb-2010-11-5-207 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011746478
    284 https://doi.org/10.1186/gb-2010-11-5-207
    285 rdf:type schema:CreativeWork
    286 sg:pub.10.1186/gb-2010-11-5-210 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042123396
    287 https://doi.org/10.1186/gb-2010-11-5-210
    288 rdf:type schema:CreativeWork
     




    Preview window. Press ESC to close (or click here)


    ...