The avian Z-linked gene DMRT1 is required for male sex determination in the chicken View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-08-26

AUTHORS

Craig A. Smith, Kelly N. Roeszler, Thomas Ohnesorg, David M. Cummins, Peter G. Farlie, Timothy J. Doran, Andrew H. Sinclair

ABSTRACT

Avian sex determination: the Z factorThe mammalian sex-determining gene SRY is well known, but the mechanisms underpinning sex determination in birds have been the subject of much debate. One hypothesis posits that the dosage of a Z-linked gene may mediate sex determination, two doses being required for male development (ZZ). Here Smith et al. show that reducing DMRT1 expression in early chicken embryos feminizes the embryonic gonads in genetically male (ZZ) embryos. This study shows that DMRT1 is required for testis formation and lends support to the theory that a double dose of a Z-linked gene is needed to make bird embryos male. More... »

PAGES

267-271

Journal

TITLE

Nature

ISSUE

7261

VOLUME

461

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature08298

DOI

http://dx.doi.org/10.1038/nature08298

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026768312

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19710650


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chick Embryo", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chickens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disorders of Sex Development", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Down-Regulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Dosage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "MicroRNAs", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ovary", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA Interference", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "SOX9 Transcription Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Characteristics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Chromosomes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Determination Processes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Testis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia", 
          "id": "http://www.grid.ac/institutes/grid.1008.9", 
          "name": [
            "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Smith", 
        "givenName": "Craig A.", 
        "id": "sg:person.0731643421.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731643421.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia", 
          "id": "http://www.grid.ac/institutes/grid.1008.9", 
          "name": [
            "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roeszler", 
        "givenName": "Kelly N.", 
        "id": "sg:person.0662121125.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662121125.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia", 
          "id": "http://www.grid.ac/institutes/grid.1008.9", 
          "name": [
            "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ohnesorg", 
        "givenName": "Thomas", 
        "id": "sg:person.01304474370.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304474370.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria 3220, Australia", 
          "id": "http://www.grid.ac/institutes/grid.413322.5", 
          "name": [
            "CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria 3220, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cummins", 
        "givenName": "David M.", 
        "id": "sg:person.01001052274.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01001052274.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia", 
          "id": "http://www.grid.ac/institutes/grid.1008.9", 
          "name": [
            "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Farlie", 
        "givenName": "Peter G.", 
        "id": "sg:person.01255762356.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255762356.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria 3220, Australia", 
          "id": "http://www.grid.ac/institutes/grid.413322.5", 
          "name": [
            "CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria 3220, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Doran", 
        "givenName": "Timothy J.", 
        "id": "sg:person.01102311310.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102311310.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia", 
          "id": "http://www.grid.ac/institutes/grid.1008.9", 
          "name": [
            "Murdoch Children\u2019s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children\u2019s Hospital, Melbourne, Victoria 3052, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sinclair", 
        "givenName": "Andrew H.", 
        "id": "sg:person.01333466427.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333466427.25"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/nature751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052603510", 
          "https://doi.org/10.1038/nature751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/6769", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002640808", 
          "https://doi.org/10.1038/6769"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00427-006-0117-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028277422", 
          "https://doi.org/10.1007/s00427-006-0117-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/45130", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034331959", 
          "https://doi.org/10.1038/45130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-213x-8-72", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002409823", 
          "https://doi.org/10.1186/1471-213x-8-72"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2009-08-26", 
    "datePublishedReg": "2009-08-26", 
    "description": "Avian sex determination: the Z factorThe mammalian sex-determining gene SRY is well known, but the mechanisms underpinning sex determination in birds have been the subject of much debate. One hypothesis posits that the dosage of a Z-linked gene may mediate sex determination, two doses being required for male development (ZZ). Here Smith et al. show that reducing DMRT1 expression in early chicken embryos feminizes the embryonic gonads in genetically male (ZZ) embryos. This study shows that DMRT1 is required for testis formation and lends support to the theory that a double dose of a Z-linked gene is needed to make bird embryos male.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/nature08298", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7261", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "461"
      }
    ], 
    "keywords": [
      "sex determination", 
      "mammalian sex-determining gene SRY", 
      "sex-determining gene SRY", 
      "male sex determination", 
      "early chicken embryos", 
      "gene DMRT1", 
      "gene SRY", 
      "DMRT1 expression", 
      "testis formation", 
      "embryonic gonads", 
      "male development", 
      "male embryos", 
      "DMRT1", 
      "chicken embryos", 
      "genes", 
      "embryos", 
      "SRY", 
      "birds", 
      "gonads", 
      "expression", 
      "chickens", 
      "mechanism", 
      "hypothesis", 
      "formation", 
      "males", 
      "development", 
      "double dose", 
      "determination", 
      "Smith et al", 
      "study", 
      "et al", 
      "dosage", 
      "doses", 
      "support", 
      "dose", 
      "al", 
      "debate", 
      "theory", 
      "subjects"
    ], 
    "name": "The avian Z-linked gene DMRT1 is required for male sex determination in the chicken", 
    "pagination": "267-271", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1026768312"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature08298"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "19710650"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature08298", 
      "https://app.dimensions.ai/details/publication/pub.1026768312"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T15:54", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_501.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/nature08298"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature08298'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature08298'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature08298'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature08298'


 

This table displays all metadata directly associated to this object as RDF triples.

245 TRIPLES      21 PREDICATES      89 URIs      76 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature08298 schema:about N07530719c002452d9d07a5e86505d15f
2 N105c7ef322d34921bf3f62c5536c5beb
3 N18a6e897edf543b6a528554aba68c274
4 N362ee166f56c48c79b6b308a4b121e9c
5 N4b80d37a1b6d4e03afd934ff18f3c5d4
6 N524cb147277c4ba5873e2b7309a3f1dd
7 N62d60d6e6f0e42b5880de2b2bc58b107
8 N68309b5ca22b4cf288dd4ac87d822076
9 N6d410daf530c4607a64745d8cfd2af21
10 N769257b1e0444fa69b4cf501e35a228e
11 N7c7d19680dd648f180f8ef9770bf75d8
12 N83709970774f418bbde43e4016de6b71
13 N8cf532327fbd44199e1c021ab8acdd05
14 N8e70f535627e441e831d5c17973c1315
15 Na3817022a4a543e5b7a2d939eb6cbcfe
16 Nc5fafcd19bbe45b2adf8ef52215a65da
17 Nda8a81d4bc8846d0b2eef1298b99a037
18 Ndfeb1dfc6b284fb18e45cb287d651bd8
19 Ne368b4e9e4064d278308d29cd8a3eb11
20 Need697d17aab4b13a1f62ad6500a4667
21 anzsrc-for:06
22 anzsrc-for:0604
23 schema:author Nad7aa3862f6b41e7b7ccc8dc9d228a0e
24 schema:citation sg:pub.10.1007/s00427-006-0117-0
25 sg:pub.10.1038/45130
26 sg:pub.10.1038/6769
27 sg:pub.10.1038/nature751
28 sg:pub.10.1186/1471-213x-8-72
29 schema:datePublished 2009-08-26
30 schema:datePublishedReg 2009-08-26
31 schema:description Avian sex determination: the Z factorThe mammalian sex-determining gene SRY is well known, but the mechanisms underpinning sex determination in birds have been the subject of much debate. One hypothesis posits that the dosage of a Z-linked gene may mediate sex determination, two doses being required for male development (ZZ). Here Smith et al. show that reducing DMRT1 expression in early chicken embryos feminizes the embryonic gonads in genetically male (ZZ) embryos. This study shows that DMRT1 is required for testis formation and lends support to the theory that a double dose of a Z-linked gene is needed to make bird embryos male.
32 schema:genre article
33 schema:isAccessibleForFree false
34 schema:isPartOf N8d8c80ddba0e460b8989c0e3c0f647e0
35 Na8624d8d68c84762b9eb5eb710eb4b10
36 sg:journal.1018957
37 schema:keywords DMRT1
38 DMRT1 expression
39 SRY
40 Smith et al
41 al
42 birds
43 chicken embryos
44 chickens
45 debate
46 determination
47 development
48 dosage
49 dose
50 doses
51 double dose
52 early chicken embryos
53 embryonic gonads
54 embryos
55 et al
56 expression
57 formation
58 gene DMRT1
59 gene SRY
60 genes
61 gonads
62 hypothesis
63 male development
64 male embryos
65 male sex determination
66 males
67 mammalian sex-determining gene SRY
68 mechanism
69 sex determination
70 sex-determining gene SRY
71 study
72 subjects
73 support
74 testis formation
75 theory
76 schema:name The avian Z-linked gene DMRT1 is required for male sex determination in the chicken
77 schema:pagination 267-271
78 schema:productId N30325f28b2934d8b83bd512b27193190
79 N4afb21a60bdd4db89fac8baa54924d4f
80 Nc1514010c61e410ba795a93157aa1ead
81 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026768312
82 https://doi.org/10.1038/nature08298
83 schema:sdDatePublished 2022-09-02T15:54
84 schema:sdLicense https://scigraph.springernature.com/explorer/license/
85 schema:sdPublisher N640e9d26a35a4c21a99aa703690abf5e
86 schema:url https://doi.org/10.1038/nature08298
87 sgo:license sg:explorer/license/
88 sgo:sdDataset articles
89 rdf:type schema:ScholarlyArticle
90 N07530719c002452d9d07a5e86505d15f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Ovary
92 rdf:type schema:DefinedTerm
93 N0ef83546947b45a3b70e8913657a7c9d rdf:first sg:person.01001052274.19
94 rdf:rest Neeaedc7ff699465b9fa6999b113efd14
95 N105c7ef322d34921bf3f62c5536c5beb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Testis
97 rdf:type schema:DefinedTerm
98 N18a6e897edf543b6a528554aba68c274 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Disorders of Sex Development
100 rdf:type schema:DefinedTerm
101 N27928f11bd3c47ad8eb671a497ff4656 rdf:first sg:person.01304474370.29
102 rdf:rest N0ef83546947b45a3b70e8913657a7c9d
103 N30325f28b2934d8b83bd512b27193190 schema:name dimensions_id
104 schema:value pub.1026768312
105 rdf:type schema:PropertyValue
106 N362ee166f56c48c79b6b308a4b121e9c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Chick Embryo
108 rdf:type schema:DefinedTerm
109 N4afb21a60bdd4db89fac8baa54924d4f schema:name doi
110 schema:value 10.1038/nature08298
111 rdf:type schema:PropertyValue
112 N4b80d37a1b6d4e03afd934ff18f3c5d4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Cell Line
114 rdf:type schema:DefinedTerm
115 N524cb147277c4ba5873e2b7309a3f1dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Sex Characteristics
117 rdf:type schema:DefinedTerm
118 N5bf074cf815244d1bc76e34e79966c55 rdf:first sg:person.01102311310.40
119 rdf:rest Ne7d5d344a6e94eecad084de59d8dbc4e
120 N62d60d6e6f0e42b5880de2b2bc58b107 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Sex Determination Processes
122 rdf:type schema:DefinedTerm
123 N640e9d26a35a4c21a99aa703690abf5e schema:name Springer Nature - SN SciGraph project
124 rdf:type schema:Organization
125 N68309b5ca22b4cf288dd4ac87d822076 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Female
127 rdf:type schema:DefinedTerm
128 N6d410daf530c4607a64745d8cfd2af21 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Gene Dosage
130 rdf:type schema:DefinedTerm
131 N769257b1e0444fa69b4cf501e35a228e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name SOX9 Transcription Factor
133 rdf:type schema:DefinedTerm
134 N7c7d19680dd648f180f8ef9770bf75d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Chickens
136 rdf:type schema:DefinedTerm
137 N83709970774f418bbde43e4016de6b71 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Sex Chromosomes
139 rdf:type schema:DefinedTerm
140 N8cf532327fbd44199e1c021ab8acdd05 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Biomarkers
142 rdf:type schema:DefinedTerm
143 N8d8c80ddba0e460b8989c0e3c0f647e0 schema:issueNumber 7261
144 rdf:type schema:PublicationIssue
145 N8e70f535627e441e831d5c17973c1315 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Transcription Factors
147 rdf:type schema:DefinedTerm
148 Na3817022a4a543e5b7a2d939eb6cbcfe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name RNA Interference
150 rdf:type schema:DefinedTerm
151 Na8624d8d68c84762b9eb5eb710eb4b10 schema:volumeNumber 461
152 rdf:type schema:PublicationVolume
153 Nad7aa3862f6b41e7b7ccc8dc9d228a0e rdf:first sg:person.0731643421.23
154 rdf:rest Nc5da5acfd77f4ae3ac67c92226724e8a
155 Nc1514010c61e410ba795a93157aa1ead schema:name pubmed_id
156 schema:value 19710650
157 rdf:type schema:PropertyValue
158 Nc5da5acfd77f4ae3ac67c92226724e8a rdf:first sg:person.0662121125.43
159 rdf:rest N27928f11bd3c47ad8eb671a497ff4656
160 Nc5fafcd19bbe45b2adf8ef52215a65da schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Animals
162 rdf:type schema:DefinedTerm
163 Nda8a81d4bc8846d0b2eef1298b99a037 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Male
165 rdf:type schema:DefinedTerm
166 Ndfeb1dfc6b284fb18e45cb287d651bd8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Models, Genetic
168 rdf:type schema:DefinedTerm
169 Ne368b4e9e4064d278308d29cd8a3eb11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Down-Regulation
171 rdf:type schema:DefinedTerm
172 Ne7d5d344a6e94eecad084de59d8dbc4e rdf:first sg:person.01333466427.25
173 rdf:rest rdf:nil
174 Neeaedc7ff699465b9fa6999b113efd14 rdf:first sg:person.01255762356.36
175 rdf:rest N5bf074cf815244d1bc76e34e79966c55
176 Need697d17aab4b13a1f62ad6500a4667 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name MicroRNAs
178 rdf:type schema:DefinedTerm
179 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
180 schema:name Biological Sciences
181 rdf:type schema:DefinedTerm
182 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
183 schema:name Genetics
184 rdf:type schema:DefinedTerm
185 sg:journal.1018957 schema:issn 0028-0836
186 1476-4687
187 schema:name Nature
188 schema:publisher Springer Nature
189 rdf:type schema:Periodical
190 sg:person.01001052274.19 schema:affiliation grid-institutes:grid.413322.5
191 schema:familyName Cummins
192 schema:givenName David M.
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01001052274.19
194 rdf:type schema:Person
195 sg:person.01102311310.40 schema:affiliation grid-institutes:grid.413322.5
196 schema:familyName Doran
197 schema:givenName Timothy J.
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102311310.40
199 rdf:type schema:Person
200 sg:person.01255762356.36 schema:affiliation grid-institutes:grid.1008.9
201 schema:familyName Farlie
202 schema:givenName Peter G.
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255762356.36
204 rdf:type schema:Person
205 sg:person.01304474370.29 schema:affiliation grid-institutes:grid.1008.9
206 schema:familyName Ohnesorg
207 schema:givenName Thomas
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304474370.29
209 rdf:type schema:Person
210 sg:person.01333466427.25 schema:affiliation grid-institutes:grid.1008.9
211 schema:familyName Sinclair
212 schema:givenName Andrew H.
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333466427.25
214 rdf:type schema:Person
215 sg:person.0662121125.43 schema:affiliation grid-institutes:grid.1008.9
216 schema:familyName Roeszler
217 schema:givenName Kelly N.
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662121125.43
219 rdf:type schema:Person
220 sg:person.0731643421.23 schema:affiliation grid-institutes:grid.1008.9
221 schema:familyName Smith
222 schema:givenName Craig A.
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731643421.23
224 rdf:type schema:Person
225 sg:pub.10.1007/s00427-006-0117-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028277422
226 https://doi.org/10.1007/s00427-006-0117-0
227 rdf:type schema:CreativeWork
228 sg:pub.10.1038/45130 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034331959
229 https://doi.org/10.1038/45130
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/6769 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002640808
232 https://doi.org/10.1038/6769
233 rdf:type schema:CreativeWork
234 sg:pub.10.1038/nature751 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052603510
235 https://doi.org/10.1038/nature751
236 rdf:type schema:CreativeWork
237 sg:pub.10.1186/1471-213x-8-72 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002409823
238 https://doi.org/10.1186/1471-213x-8-72
239 rdf:type schema:CreativeWork
240 grid-institutes:grid.1008.9 schema:alternateName Murdoch Children’s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children’s Hospital, Melbourne, Victoria 3052, Australia
241 schema:name Murdoch Children’s Research Institute and Department of Paediatrics, The University of Melbourne, Royal Children’s Hospital, Melbourne, Victoria 3052, Australia
242 rdf:type schema:Organization
243 grid-institutes:grid.413322.5 schema:alternateName CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria 3220, Australia
244 schema:name CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria 3220, Australia
245 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...