The cancer genome View Full Text


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Article Info

DATE

2009-04

AUTHORS

Michael R. Stratton, Peter J. Campbell, P. Andrew Futreal

ABSTRACT

The cancer genomics eraSince the discovery in 1982 of the link between HRAS gene mutations and bladder cancer, about 100,000 abnormal genes have been identified in cancer patients. As a result, much has been learned about the development of cancer, but with so many distinct cancer and tissue types, there is much more to be learned. Now with the development of massively parallel DNA sequencing, hundreds of millions of cancer-related mutations will soon be revealed. In a broad-ranging review, Michael Stratton, Peter Campbell and Andrew Futreal look back at the achievements of cancer genomics, and forward to the prospect that the complete DNA sequencing of large numbers of cancers will help us move towards a deeper understanding of how to treat cancers. More... »

PAGES

719-724

References to SciGraph publications

  • 1982-11. Mechanism of activation of a human oncogene in NATURE
  • 2008-02. Drug Insight: gastrointestinal stromal tumors (GIST)—the solid tumor model for cancer-specific treatment in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2002-06-09. Mutations of the BRAF gene in human cancer in NATURE
  • 2007-07-11. Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer in NATURE
  • 1998-12. Genetic instabilities in human cancers in NATURE
  • 1973-06. A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining in NATURE
  • 1982-11. A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene in NATURE
  • 2005-05-22. A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer in NATURE GENETICS
  • 2009-03-29. Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer in NATURE GENETICS
  • 2008-11. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome in NATURE
  • 2004-03. A census of human cancer genes in NATURE REVIEWS CANCER
  • 2007-03. Patterns of somatic mutation in human cancer genomes in NATURE
  • 2008-12-23. Trastuzumab as adjuvant systemic therapy for HER2-positive breast cancer in NATURE REVIEWS CLINICAL ONCOLOGY
  • 1890-02. Ueber asymmetrische Zelltheilung in Epithelkrebsen und deren biologische Bedeutung in VIRCHOWS ARCHIV
  • 2004-09-29. Intragenic ERBB2 kinase mutations in tumours in NATURE
  • 1953-04-25. Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid in NATURE
  • 2008-10. Somatic mutations affect key pathways in lung adenocarcinoma in NATURE
  • 2004-11-17. Targeted cancer therapy in NATURE
  • 1981-03. Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts in NATURE
  • 2006-08-07. Mitochondrial DNA mutations in human cancer in ONCOGENE
  • 2008-09-04. Comprehensive genomic characterization defines human glioblastoma genes and core pathways in NATURE
  • 2006-06-25. Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing in NATURE MEDICINE
  • 2008-04-27. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing in NATURE GENETICS
  • Journal

    TITLE

    Nature

    ISSUE

    7239

    VOLUME

    458

    Related Patents

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature07943

    DOI

    http://dx.doi.org/10.1038/nature07943

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1004829095

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19360079


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