Structure of the connexin 26 gap junction channel at 3.5 Å resolution View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-04

AUTHORS

Shoji Maeda, So Nakagawa, Michihiro Suga, Eiki Yamashita, Atsunori Oshima, Yoshinori Fujiyoshi, Tomitake Tsukihara

ABSTRACT

Gap junctions consist of arrays of intercellular channels between adjacent cells that permit the exchange of ions and small molecules. Here we report the crystal structure of the gap junction channel formed by human connexin 26 (Cx26, also known as GJB2) at 3.5 A resolution, and discuss structural determinants of solute transport through the channel. The density map showed the two membrane-spanning hemichannels and the arrangement of the four transmembrane helices of the six protomers forming each hemichannel. The hemichannels feature a positively charged cytoplasmic entrance, a funnel, a negatively charged transmembrane pathway, and an extracellular cavity. The pore is narrowed at the funnel, which is formed by the six amino-terminal helices lining the wall of the channel, which thus determines the molecular size restriction at the channel entrance. The structure of the Cx26 gap junction channel also has implications for the gating of the channel by the transjunctional voltage. More... »

PAGES

597

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature07869

DOI

http://dx.doi.org/10.1038/nature07869

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022476406

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19340074


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Connexin 26", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Connexins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Crystallography, X-Ray", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gap Junctions", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ion Channel Gating", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Multimerization", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Structure, Quaternary", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spodoptera", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Osaka University", 
          "id": "https://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Institute for Protein Research, Osaka University, OLABB, 6-2-3, Furuedai, Suita, Osaka 565-0874, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maeda", 
        "givenName": "Shoji", 
        "id": "sg:person.0606613636.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606613636.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka University", 
          "id": "https://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Institute for Protein Research, Osaka University, OLABB, 6-2-3, Furuedai, Suita, Osaka 565-0874, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakagawa", 
        "givenName": "So", 
        "id": "sg:person.014747222722.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014747222722.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka University", 
          "id": "https://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Institute for Protein Research, Osaka University, OLABB, 6-2-3, Furuedai, Suita, Osaka 565-0874, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suga", 
        "givenName": "Michihiro", 
        "id": "sg:person.01212712452.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212712452.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka University", 
          "id": "https://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Institute for Protein Research, Osaka University, OLABB, 6-2-3, Furuedai, Suita, Osaka 565-0874, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamashita", 
        "givenName": "Eiki", 
        "id": "sg:person.0713441134.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713441134.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Biophysics, Graduate School of Science, Kyoto University, Oiwake, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oshima", 
        "givenName": "Atsunori", 
        "id": "sg:person.01121170375.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121170375.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Biophysics, Graduate School of Science, Kyoto University, Oiwake, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fujiyoshi", 
        "givenName": "Yoshinori", 
        "id": "sg:person.01077633456.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077633456.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka University", 
          "id": "https://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Institute for Protein Research, Osaka University, OLABB, 6-2-3, Furuedai, Suita, Osaka 565-0874, Japan", 
            "Picobiology Institute, Graduate School of Life Science, University of Hyogo, Kamigohori, Akoh, Hyogo 678-1297, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsukihara", 
        "givenName": "Tomitake", 
        "id": "sg:person.01235336457.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235336457.47"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1083/jcb.140.5.1187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001557751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/283545a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001941451", 
          "https://doi.org/10.1038/283545a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/mol.106.027508", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003290336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0021889892009944", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003451988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(00)76539-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003497717"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0076-6879(97)76066-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004907170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.79.15.4545", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005026764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.181342398", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006228920"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(01)75687-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009725990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature01748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010350589", 
          "https://doi.org/10.1038/nature01748"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature01748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010350589", 
          "https://doi.org/10.1038/nature01748"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/307609a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011839755", 
          "https://doi.org/10.1038/307609a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/368348a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012957602", 
          "https://doi.org/10.1038/368348a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/abbi.2000.1989", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013323174"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2008.150805", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014193012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0108767390010224", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014210169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1085/jgp.200308861", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014705285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0079-6107(99)00008-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015163880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/387080a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017615074", 
          "https://doi.org/10.1038/387080a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444995010638", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018273961"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1529/biophysj.103.038448", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019231579"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbamem.2003.10.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019349686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444998003254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019779527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444904019158", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020281098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444996012255", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020405374"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.115.1.141", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020569499"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cardiores.2003.12.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022423793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444994003112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025573949"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1085/jgp.77.1.95", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026745742"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/cdf365", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029532881"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444903017694", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030505707"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1997.1580", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030981069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(95)80356-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034422176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/365847a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035932436", 
          "https://doi.org/10.1038/365847a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/15419060802013588", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035985836"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0703704104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036238695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m207713200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037741496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.93.12.5836", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038065028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.200207060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038191693"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molcel.2004.08.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041231329"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/15419060109080721", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042186989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbamem.2004.01.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042629176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(97)78840-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046349447"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0969-2126(00)80020-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046355423"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(00)76485-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046709787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81282-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047804901"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20051922", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047832839"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20051922", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047832839"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1529/biophysj.103.036350", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048083609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0962-8924(98)01372-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049133031"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0962-8924(00)01866-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050620149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pbiomolbio.2007.03.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051807735"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.ph.54.030192.002541", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052348841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0021889893005588", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053164838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0033583501003705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053794880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0033583501003705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053794880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1085/jgp.116.1.13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058438871"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.283.5405.1176", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062564257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/physrev.00007.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063200513"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2009-04", 
    "datePublishedReg": "2009-04-01", 
    "description": "Gap junctions consist of arrays of intercellular channels between adjacent cells that permit the exchange of ions and small molecules. Here we report the crystal structure of the gap junction channel formed by human connexin 26 (Cx26, also known as GJB2) at 3.5 A resolution, and discuss structural determinants of solute transport through the channel. The density map showed the two membrane-spanning hemichannels and the arrangement of the four transmembrane helices of the six protomers forming each hemichannel. The hemichannels feature a positively charged cytoplasmic entrance, a funnel, a negatively charged transmembrane pathway, and an extracellular cavity. The pore is narrowed at the funnel, which is formed by the six amino-terminal helices lining the wall of the channel, which thus determines the molecular size restriction at the channel entrance. The structure of the Cx26 gap junction channel also has implications for the gating of the channel by the transjunctional voltage.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nature07869", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5946542", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5882493", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7238", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "458"
      }
    ], 
    "name": "Structure of the connexin 26 gap junction channel at 3.5\u2009\u00c5 resolution", 
    "pagination": "597", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "6b1527e574094010374e27948b1ddd33c2efdbbfe6704bd5d7283e3c56636adc"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "19340074"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature07869"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1022476406"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature07869", 
      "https://app.dimensions.ai/details/publication/pub.1022476406"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:13", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000338_0000000338/records_47991_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/nature07869"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature07869'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature07869'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature07869'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature07869'


 

This table displays all metadata directly associated to this object as RDF triples.

341 TRIPLES      21 PREDICATES      97 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature07869 schema:about N11dc4f9f0ae8400a993ca3f99dd7150a
2 N3525a8c390334f329bd796abb56fa3c2
3 N5aef5de8358e48d7af3c551a1b25d815
4 N6cb7d94cdb144fb7a08200aa91648cab
5 N72cbb8c4a7aa42418c4cd04244905e9d
6 N827765f26fa64d0d8f9f55c8b52cd7e1
7 N9d06620d14f54736a46c5fb9dc632985
8 Nb923ac7e19b44dc99e0e1ca76dce29b5
9 Ncc4c795277634accb559c4afdaf2f103
10 Nd3577b7cbc114d8cbf5eb0fe8450d255
11 Ndb3a47e4a077410795f9e8fc729c8e61
12 Nf7937ef224d64fe6845b20d427febb39
13 anzsrc-for:06
14 anzsrc-for:0601
15 schema:author N7ea979df29b9478a9b574224ecb0e428
16 schema:citation sg:pub.10.1038/283545a0
17 sg:pub.10.1038/307609a0
18 sg:pub.10.1038/365847a0
19 sg:pub.10.1038/368348a0
20 sg:pub.10.1038/387080a0
21 sg:pub.10.1038/nature01748
22 https://doi.org/10.1006/abbi.2000.1989
23 https://doi.org/10.1006/jmbi.1997.1580
24 https://doi.org/10.1016/j.bbamem.2003.10.020
25 https://doi.org/10.1016/j.bbamem.2004.01.008
26 https://doi.org/10.1016/j.cardiores.2003.12.030
27 https://doi.org/10.1016/j.molcel.2004.08.016
28 https://doi.org/10.1016/j.pbiomolbio.2007.03.005
29 https://doi.org/10.1016/s0006-3495(00)76485-x
30 https://doi.org/10.1016/s0006-3495(00)76539-8
31 https://doi.org/10.1016/s0006-3495(01)75687-1
32 https://doi.org/10.1016/s0006-3495(95)80356-5
33 https://doi.org/10.1016/s0006-3495(97)78840-4
34 https://doi.org/10.1016/s0076-6879(97)76066-x
35 https://doi.org/10.1016/s0079-6107(99)00008-5
36 https://doi.org/10.1016/s0092-8674(00)81282-9
37 https://doi.org/10.1016/s0962-8924(00)01866-3
38 https://doi.org/10.1016/s0962-8924(98)01372-5
39 https://doi.org/10.1016/s0969-2126(00)80020-9
40 https://doi.org/10.1017/s0033583501003705
41 https://doi.org/10.1042/bj20051922
42 https://doi.org/10.1073/pnas.0703704104
43 https://doi.org/10.1073/pnas.181342398
44 https://doi.org/10.1073/pnas.79.15.4545
45 https://doi.org/10.1073/pnas.93.12.5836
46 https://doi.org/10.1074/jbc.m207713200
47 https://doi.org/10.1080/15419060802013588
48 https://doi.org/10.1083/jcb.115.1.141
49 https://doi.org/10.1083/jcb.140.5.1187
50 https://doi.org/10.1083/jcb.200207060
51 https://doi.org/10.1085/jgp.116.1.13
52 https://doi.org/10.1085/jgp.200308861
53 https://doi.org/10.1085/jgp.77.1.95
54 https://doi.org/10.1093/emboj/cdf365
55 https://doi.org/10.1107/s0021889892009944
56 https://doi.org/10.1107/s0021889893005588
57 https://doi.org/10.1107/s0108767390010224
58 https://doi.org/10.1107/s0907444903017694
59 https://doi.org/10.1107/s0907444904019158
60 https://doi.org/10.1107/s0907444994003112
61 https://doi.org/10.1107/s0907444995010638
62 https://doi.org/10.1107/s0907444996012255
63 https://doi.org/10.1107/s0907444998003254
64 https://doi.org/10.1113/jphysiol.2008.150805
65 https://doi.org/10.1124/mol.106.027508
66 https://doi.org/10.1126/science.283.5405.1176
67 https://doi.org/10.1146/annurev.ph.54.030192.002541
68 https://doi.org/10.1152/physrev.00007.2003
69 https://doi.org/10.1529/biophysj.103.036350
70 https://doi.org/10.1529/biophysj.103.038448
71 https://doi.org/10.3109/15419060109080721
72 schema:datePublished 2009-04
73 schema:datePublishedReg 2009-04-01
74 schema:description Gap junctions consist of arrays of intercellular channels between adjacent cells that permit the exchange of ions and small molecules. Here we report the crystal structure of the gap junction channel formed by human connexin 26 (Cx26, also known as GJB2) at 3.5 A resolution, and discuss structural determinants of solute transport through the channel. The density map showed the two membrane-spanning hemichannels and the arrangement of the four transmembrane helices of the six protomers forming each hemichannel. The hemichannels feature a positively charged cytoplasmic entrance, a funnel, a negatively charged transmembrane pathway, and an extracellular cavity. The pore is narrowed at the funnel, which is formed by the six amino-terminal helices lining the wall of the channel, which thus determines the molecular size restriction at the channel entrance. The structure of the Cx26 gap junction channel also has implications for the gating of the channel by the transjunctional voltage.
75 schema:genre research_article
76 schema:inLanguage en
77 schema:isAccessibleForFree false
78 schema:isPartOf N4a6cfadce05444108bdb0dacd790128e
79 Nfa8bf7c43b7740edacb17d2c6d901ef4
80 sg:journal.1018957
81 schema:name Structure of the connexin 26 gap junction channel at 3.5 Å resolution
82 schema:pagination 597
83 schema:productId N1743335b02d74e3e8b2894cf5820a88b
84 N517286cde868411e97e697309f3b43b8
85 N7c8291337fa34d4f9fe9e18a6f454aab
86 N90f1bfebd839488088f82a1a60d46ce7
87 Nbc4488c6f6a941b1a33ddb68f44c1ea3
88 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022476406
89 https://doi.org/10.1038/nature07869
90 schema:sdDatePublished 2019-04-11T09:13
91 schema:sdLicense https://scigraph.springernature.com/explorer/license/
92 schema:sdPublisher N96093c293969447bb1a3bf50df32029a
93 schema:url https://www.nature.com/articles/nature07869
94 sgo:license sg:explorer/license/
95 sgo:sdDataset articles
96 rdf:type schema:ScholarlyArticle
97 N11dc4f9f0ae8400a993ca3f99dd7150a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Models, Molecular
99 rdf:type schema:DefinedTerm
100 N1743335b02d74e3e8b2894cf5820a88b schema:name dimensions_id
101 schema:value pub.1022476406
102 rdf:type schema:PropertyValue
103 N3525a8c390334f329bd796abb56fa3c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Cell Line
105 rdf:type schema:DefinedTerm
106 N417ee119dc6d4959ac5e211109416c59 rdf:first sg:person.01077633456.74
107 rdf:rest N84ba7a92e3f84b7d8e2fcc76f25be005
108 N4a6cfadce05444108bdb0dacd790128e schema:volumeNumber 458
109 rdf:type schema:PublicationVolume
110 N51307f7f34fa4bb782cc4e99ddc1bac7 rdf:first sg:person.01212712452.70
111 rdf:rest N6b8e0afae252487b8902c3560d7b0b8c
112 N517286cde868411e97e697309f3b43b8 schema:name readcube_id
113 schema:value 6b1527e574094010374e27948b1ddd33c2efdbbfe6704bd5d7283e3c56636adc
114 rdf:type schema:PropertyValue
115 N5aef5de8358e48d7af3c551a1b25d815 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Connexin 26
117 rdf:type schema:DefinedTerm
118 N6b8e0afae252487b8902c3560d7b0b8c rdf:first sg:person.0713441134.06
119 rdf:rest Nf4a0302133744d93941406e5c86a0360
120 N6cb7d94cdb144fb7a08200aa91648cab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Gap Junctions
122 rdf:type schema:DefinedTerm
123 N72cbb8c4a7aa42418c4cd04244905e9d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Protein Multimerization
125 rdf:type schema:DefinedTerm
126 N7c8291337fa34d4f9fe9e18a6f454aab schema:name pubmed_id
127 schema:value 19340074
128 rdf:type schema:PropertyValue
129 N7ea979df29b9478a9b574224ecb0e428 rdf:first sg:person.0606613636.42
130 rdf:rest Ne75a3eb930034eb2aaf5bd621842f02f
131 N827765f26fa64d0d8f9f55c8b52cd7e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Connexins
133 rdf:type schema:DefinedTerm
134 N84ba7a92e3f84b7d8e2fcc76f25be005 rdf:first sg:person.01235336457.47
135 rdf:rest rdf:nil
136 N90f1bfebd839488088f82a1a60d46ce7 schema:name nlm_unique_id
137 schema:value 0410462
138 rdf:type schema:PropertyValue
139 N96093c293969447bb1a3bf50df32029a schema:name Springer Nature - SN SciGraph project
140 rdf:type schema:Organization
141 N9d06620d14f54736a46c5fb9dc632985 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Spodoptera
143 rdf:type schema:DefinedTerm
144 Nb923ac7e19b44dc99e0e1ca76dce29b5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Humans
146 rdf:type schema:DefinedTerm
147 Nbc4488c6f6a941b1a33ddb68f44c1ea3 schema:name doi
148 schema:value 10.1038/nature07869
149 rdf:type schema:PropertyValue
150 Ncc4c795277634accb559c4afdaf2f103 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Crystallography, X-Ray
152 rdf:type schema:DefinedTerm
153 Nd3577b7cbc114d8cbf5eb0fe8450d255 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Animals
155 rdf:type schema:DefinedTerm
156 Ndb3a47e4a077410795f9e8fc729c8e61 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Protein Structure, Quaternary
158 rdf:type schema:DefinedTerm
159 Ne75a3eb930034eb2aaf5bd621842f02f rdf:first sg:person.014747222722.84
160 rdf:rest N51307f7f34fa4bb782cc4e99ddc1bac7
161 Nf4a0302133744d93941406e5c86a0360 rdf:first sg:person.01121170375.52
162 rdf:rest N417ee119dc6d4959ac5e211109416c59
163 Nf7937ef224d64fe6845b20d427febb39 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Ion Channel Gating
165 rdf:type schema:DefinedTerm
166 Nfa8bf7c43b7740edacb17d2c6d901ef4 schema:issueNumber 7238
167 rdf:type schema:PublicationIssue
168 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
169 schema:name Biological Sciences
170 rdf:type schema:DefinedTerm
171 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
172 schema:name Biochemistry and Cell Biology
173 rdf:type schema:DefinedTerm
174 sg:grant.5882493 http://pending.schema.org/fundedItem sg:pub.10.1038/nature07869
175 rdf:type schema:MonetaryGrant
176 sg:grant.5946542 http://pending.schema.org/fundedItem sg:pub.10.1038/nature07869
177 rdf:type schema:MonetaryGrant
178 sg:journal.1018957 schema:issn 0090-0028
179 1476-4687
180 schema:name Nature
181 rdf:type schema:Periodical
182 sg:person.01077633456.74 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
183 schema:familyName Fujiyoshi
184 schema:givenName Yoshinori
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077633456.74
186 rdf:type schema:Person
187 sg:person.01121170375.52 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
188 schema:familyName Oshima
189 schema:givenName Atsunori
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121170375.52
191 rdf:type schema:Person
192 sg:person.01212712452.70 schema:affiliation https://www.grid.ac/institutes/grid.136593.b
193 schema:familyName Suga
194 schema:givenName Michihiro
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212712452.70
196 rdf:type schema:Person
197 sg:person.01235336457.47 schema:affiliation https://www.grid.ac/institutes/grid.136593.b
198 schema:familyName Tsukihara
199 schema:givenName Tomitake
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235336457.47
201 rdf:type schema:Person
202 sg:person.014747222722.84 schema:affiliation https://www.grid.ac/institutes/grid.136593.b
203 schema:familyName Nakagawa
204 schema:givenName So
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014747222722.84
206 rdf:type schema:Person
207 sg:person.0606613636.42 schema:affiliation https://www.grid.ac/institutes/grid.136593.b
208 schema:familyName Maeda
209 schema:givenName Shoji
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606613636.42
211 rdf:type schema:Person
212 sg:person.0713441134.06 schema:affiliation https://www.grid.ac/institutes/grid.136593.b
213 schema:familyName Yamashita
214 schema:givenName Eiki
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713441134.06
216 rdf:type schema:Person
217 sg:pub.10.1038/283545a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001941451
218 https://doi.org/10.1038/283545a0
219 rdf:type schema:CreativeWork
220 sg:pub.10.1038/307609a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011839755
221 https://doi.org/10.1038/307609a0
222 rdf:type schema:CreativeWork
223 sg:pub.10.1038/365847a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035932436
224 https://doi.org/10.1038/365847a0
225 rdf:type schema:CreativeWork
226 sg:pub.10.1038/368348a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012957602
227 https://doi.org/10.1038/368348a0
228 rdf:type schema:CreativeWork
229 sg:pub.10.1038/387080a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017615074
230 https://doi.org/10.1038/387080a0
231 rdf:type schema:CreativeWork
232 sg:pub.10.1038/nature01748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010350589
233 https://doi.org/10.1038/nature01748
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1006/abbi.2000.1989 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013323174
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1006/jmbi.1997.1580 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030981069
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1016/j.bbamem.2003.10.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019349686
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1016/j.bbamem.2004.01.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042629176
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1016/j.cardiores.2003.12.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022423793
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1016/j.molcel.2004.08.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041231329
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1016/j.pbiomolbio.2007.03.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051807735
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1016/s0006-3495(00)76485-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046709787
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/s0006-3495(00)76539-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003497717
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/s0006-3495(01)75687-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009725990
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/s0006-3495(95)80356-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034422176
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/s0006-3495(97)78840-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046349447
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/s0076-6879(97)76066-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004907170
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/s0079-6107(99)00008-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015163880
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/s0092-8674(00)81282-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047804901
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1016/s0962-8924(00)01866-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050620149
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1016/s0962-8924(98)01372-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049133031
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/s0969-2126(00)80020-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046355423
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1017/s0033583501003705 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053794880
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1042/bj20051922 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047832839
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1073/pnas.0703704104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036238695
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1073/pnas.181342398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006228920
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1073/pnas.79.15.4545 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005026764
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1073/pnas.93.12.5836 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038065028
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1074/jbc.m207713200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037741496
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1080/15419060802013588 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035985836
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1083/jcb.115.1.141 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020569499
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1083/jcb.140.5.1187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001557751
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1083/jcb.200207060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038191693
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1085/jgp.116.1.13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058438871
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1085/jgp.200308861 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014705285
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1085/jgp.77.1.95 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026745742
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1093/emboj/cdf365 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029532881
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1107/s0021889892009944 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003451988
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1107/s0021889893005588 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053164838
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1107/s0108767390010224 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014210169
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1107/s0907444903017694 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030505707
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1107/s0907444904019158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020281098
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1107/s0907444994003112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025573949
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1107/s0907444995010638 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018273961
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1107/s0907444996012255 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020405374
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1107/s0907444998003254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019779527
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1113/jphysiol.2008.150805 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014193012
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1124/mol.106.027508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003290336
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1126/science.283.5405.1176 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062564257
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1146/annurev.ph.54.030192.002541 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052348841
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1152/physrev.00007.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063200513
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1529/biophysj.103.036350 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048083609
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1529/biophysj.103.038448 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019231579
332 rdf:type schema:CreativeWork
333 https://doi.org/10.3109/15419060109080721 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042186989
334 rdf:type schema:CreativeWork
335 https://www.grid.ac/institutes/grid.136593.b schema:alternateName Osaka University
336 schema:name Institute for Protein Research, Osaka University, OLABB, 6-2-3, Furuedai, Suita, Osaka 565-0874, Japan
337 Picobiology Institute, Graduate School of Life Science, University of Hyogo, Kamigohori, Akoh, Hyogo 678-1297, Japan
338 rdf:type schema:Organization
339 https://www.grid.ac/institutes/grid.258799.8 schema:alternateName Kyoto University
340 schema:name Department of Biophysics, Graduate School of Science, Kyoto University, Oiwake, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan
341 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...