DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-11

AUTHORS

Timothy J. Ley, Elaine R. Mardis, Li Ding, Bob Fulton, Michael D. McLellan, Ken Chen, David Dooling, Brian H. Dunford-Shore, Sean McGrath, Matthew Hickenbotham, Lisa Cook, Rachel Abbott, David E. Larson, Dan C. Koboldt, Craig Pohl, Scott Smith, Amy Hawkins, Scott Abbott, Devin Locke, LaDeana W. Hillier, Tracie Miner, Lucinda Fulton, Vincent Magrini, Todd Wylie, Jarret Glasscock, Joshua Conyers, Nathan Sander, Xiaoqi Shi, John R. Osborne, Patrick Minx, David Gordon, Asif Chinwalla, Yu Zhao, Rhonda E. Ries, Jacqueline E. Payton, Peter Westervelt, Michael H. Tomasson, Mark Watson, Jack Baty, Jennifer Ivanovich, Sharon Heath, William D. Shannon, Rakesh Nagarajan, Matthew J. Walter, Daniel C. Link, Timothy A. Graubert, John F. DiPersio, Richard K. Wilson

ABSTRACT

Acute myeloid leukaemia is a highly malignant haematopoietic tumour that affects about 13,000 adults in the United States each year. The treatment of this disease has changed little in the past two decades, because most of the genetic events that initiate the disease remain undiscovered. Whole-genome sequencing is now possible at a reasonable cost and timeframe to use this approach for the unbiased discovery of tumour-specific somatic mutations that alter the protein-coding genes. Here we present the results obtained from sequencing a typical acute myeloid leukaemia genome, and its matched normal counterpart obtained from the same patient's skin. We discovered ten genes with acquired mutations; two were previously described mutations that are thought to contribute to tumour progression, and eight were new mutations present in virtually all tumour cells at presentation and relapse, the function of which is not yet known. Our study establishes whole-genome sequencing as an unbiased method for discovering cancer-initiating mutations in previously unidentified genes that may respond to targeted therapies. More... »

PAGES

66

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature07485

DOI

http://dx.doi.org/10.1038/nature07485

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034796960

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18987736


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Case-Control Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Progression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Profiling", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation, Neoplastic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genomics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Leukemia, Myeloid, Acute", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutagenesis, Insertional", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Single Nucleotide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recurrence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Analysis, DNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Deletion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Skin", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Medicine,", 
            "Department of Genetics,", 
            "The Genome Center at Washington University,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ley", 
        "givenName": "Timothy J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Genetics,", 
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mardis", 
        "givenName": "Elaine R.", 
        "id": "sg:person.01023627236.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023627236.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Genetics,", 
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ding", 
        "givenName": "Li", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fulton", 
        "givenName": "Bob", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McLellan", 
        "givenName": "Michael D.", 
        "id": "sg:person.01164172261.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01164172261.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Ken", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dooling", 
        "givenName": "David", 
        "id": "sg:person.01300420661.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300420661.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dunford-Shore", 
        "givenName": "Brian H.", 
        "id": "sg:person.01304651323.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304651323.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McGrath", 
        "givenName": "Sean", 
        "id": "sg:person.0744070252.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744070252.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hickenbotham", 
        "givenName": "Matthew", 
        "id": "sg:person.01257441450.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257441450.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cook", 
        "givenName": "Lisa", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abbott", 
        "givenName": "Rachel", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Larson", 
        "givenName": "David E.", 
        "id": "sg:person.01053604761.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053604761.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koboldt", 
        "givenName": "Dan C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pohl", 
        "givenName": "Craig", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Smith", 
        "givenName": "Scott", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hawkins", 
        "givenName": "Amy", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abbott", 
        "givenName": "Scott", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Locke", 
        "givenName": "Devin", 
        "id": "sg:person.0730273326.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730273326.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "The Genome Center at Washington University,", 
            "Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hillier", 
        "givenName": "LaDeana W.", 
        "id": "sg:person.01014313442.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014313442.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miner", 
        "givenName": "Tracie", 
        "id": "sg:person.01344004151.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344004151.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fulton", 
        "givenName": "Lucinda", 
        "id": "sg:person.010365471537.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010365471537.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Genetics,", 
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Magrini", 
        "givenName": "Vincent", 
        "id": "sg:person.01030001224.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030001224.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wylie", 
        "givenName": "Todd", 
        "id": "sg:person.0626250070.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626250070.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Glasscock", 
        "givenName": "Jarret", 
        "id": "sg:person.01325554650.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325554650.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Conyers", 
        "givenName": "Joshua", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sander", 
        "givenName": "Nathan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shi", 
        "givenName": "Xiaoqi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Osborne", 
        "givenName": "John R.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Minx", 
        "givenName": "Patrick", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gordon", 
        "givenName": "David", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Genome Center at Washington University,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chinwalla", 
        "givenName": "Asif", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medicine,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhao", 
        "givenName": "Yu", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Medicine,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ries", 
        "givenName": "Rhonda E.", 
        "id": "sg:person.0754602624.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754602624.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pathology and Immunology,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Payton", 
        "givenName": "Jacqueline E.", 
        "id": "sg:person.01051055051.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051055051.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Medicine,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Westervelt", 
        "givenName": "Peter", 
        "id": "sg:person.0706035023.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706035023.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Medicine,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tomasson", 
        "givenName": "Michael H.", 
        "id": "sg:person.0707031611.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707031611.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "The Genome Center at Washington University,", 
            "Siteman Cancer Center,", 
            "Department of Pathology and Immunology,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Watson", 
        "givenName": "Mark", 
        "id": "sg:person.011243173122.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011243173122.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Biostatistics, and,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Baty", 
        "givenName": "Jack", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Siteman Cancer Center,", 
            "Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63108, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ivanovich", 
        "givenName": "Jennifer", 
        "id": "sg:person.0664667051.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664667051.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Medicine,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heath", 
        "givenName": "Sharon", 
        "id": "sg:person.01250443136.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250443136.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Medicine,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shannon", 
        "givenName": "William D.", 
        "id": "sg:person.07652030364.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07652030364.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Siteman Cancer Center,", 
            "Department of Pathology and Immunology,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nagarajan", 
        "givenName": "Rakesh", 
        "id": "sg:person.0726230426.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726230426.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Medicine,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Walter", 
        "givenName": "Matthew J.", 
        "id": "sg:person.01301532051.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301532051.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Medicine,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Link", 
        "givenName": "Daniel C.", 
        "id": "sg:person.016375226437.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016375226437.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Medicine,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Graubert", 
        "givenName": "Timothy A.", 
        "id": "sg:person.01347645251.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347645251.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Medicine,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "DiPersio", 
        "givenName": "John F.", 
        "id": "sg:person.0755514036.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755514036.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Washington University in St. Louis", 
          "id": "https://www.grid.ac/institutes/grid.4367.6", 
          "name": [
            "Department of Genetics,", 
            "The Genome Center at Washington University,", 
            "Siteman Cancer Center,"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wilson", 
        "givenName": "Richard K.", 
        "id": "sg:person.013076541047.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013076541047.38"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1200/jco.2005.04.5450", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000372533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2005-08-3167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001126578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.1179", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001773338", 
          "https://doi.org/10.1038/nmeth.1179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.122233699", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003891362"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0268-960x(03)00040-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004829505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0268-960x(03)00040-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004829505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2006-06-001149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005044116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2007-09-113027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007947126"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature05690", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014017146", 
          "https://doi.org/10.1038/nature05690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa041974", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020502159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2007-07-101394", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020817577"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccr.2007.11.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021461434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2141.2007.06909.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023895017"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2002-03-0772", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024049275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2404145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025528247", 
          "https://doi.org/10.1038/sj.leu.2404145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2404145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025528247", 
          "https://doi.org/10.1038/sj.leu.2404145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa040465", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027799720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pbio.0050254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028942453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.142103599", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029045939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa031046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029492007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2403099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029950764", 
          "https://doi.org/10.1038/sj.leu.2403099"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2403099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029950764", 
          "https://doi.org/10.1038/sj.leu.2403099"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2105-9-239", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040243916", 
          "https://doi.org/10.1186/1471-2105-9-239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2105-9-239", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040243916", 
          "https://doi.org/10.1186/1471-2105-9-239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2007-03-081216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046183450"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.078212.108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047542880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06884", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047672670", 
          "https://doi.org/10.1038/nature06884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/ca.2007.0010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052065817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06866", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052983633", 
          "https://doi.org/10.1038/nature06866"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/cc.4.11.2174", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072298154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077003884", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083319627", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-11", 
    "datePublishedReg": "2008-11-01", 
    "description": "Acute myeloid leukaemia is a highly malignant haematopoietic tumour that affects about 13,000 adults in the United States each year. The treatment of this disease has changed little in the past two decades, because most of the genetic events that initiate the disease remain undiscovered. Whole-genome sequencing is now possible at a reasonable cost and timeframe to use this approach for the unbiased discovery of tumour-specific somatic mutations that alter the protein-coding genes. Here we present the results obtained from sequencing a typical acute myeloid leukaemia genome, and its matched normal counterpart obtained from the same patient's skin. We discovered ten genes with acquired mutations; two were previously described mutations that are thought to contribute to tumour progression, and eight were new mutations present in virtually all tumour cells at presentation and relapse, the function of which is not yet known. Our study establishes whole-genome sequencing as an unbiased method for discovering cancer-initiating mutations in previously unidentified genes that may respond to targeted therapies.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nature07485", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2699308", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7218", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "456"
      }
    ], 
    "name": "DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome", 
    "pagination": "66", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "a5c286f8c234e23133a1fe0f8b12108876603d3172332442ec911b92c5203646"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18987736"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature07485"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1034796960"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature07485", 
      "https://app.dimensions.ai/details/publication/pub.1034796960"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T12:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/nature07485"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature07485'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature07485'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature07485'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature07485'


 

This table displays all metadata directly associated to this object as RDF triples.

607 TRIPLES      21 PREDICATES      72 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature07485 schema:about N12a795e9efe94df2a7608fe9d76b7283
2 N180d190011ac4abea7394db7f0aa9892
3 N2071da35c4ad4da5b60fd4e3029e948f
4 N2768213a41824e59b933f006f8a9f293
5 N3766423dbd3c432db77bb0500c522a64
6 N48689ed566804884a1585966e3b7a12d
7 N4fe1ca1fe6c849f5b7097101979f25d4
8 N8fe090a11b5e4cdea06b5f3245307bf8
9 N989eeca7929a45d0b138d0851604673a
10 Nc34d88d90fb847a482a5eac92b11b9b3
11 Nc79d2cca0e384127886119372ba2c0fc
12 Nd7ba0128c84543dfb7e22986a9a07986
13 Ne4d1aa78730541268c650395ea92d473
14 Ne63c54cb97df4129bc67d93c39287a95
15 Nfaf5894787b6429fa70f793b8a191bcb
16 anzsrc-for:11
17 anzsrc-for:1112
18 schema:author Na4f59a2824f9443ab7d1b53afa5826dd
19 schema:citation sg:pub.10.1038/nature05690
20 sg:pub.10.1038/nature06866
21 sg:pub.10.1038/nature06884
22 sg:pub.10.1038/nmeth.1179
23 sg:pub.10.1038/sj.leu.2403099
24 sg:pub.10.1038/sj.leu.2404145
25 sg:pub.10.1186/1471-2105-9-239
26 https://app.dimensions.ai/details/publication/pub.1077003884
27 https://app.dimensions.ai/details/publication/pub.1083319627
28 https://doi.org/10.1016/j.ccr.2007.11.005
29 https://doi.org/10.1016/s0268-960x(03)00040-7
30 https://doi.org/10.1056/nejmoa031046
31 https://doi.org/10.1056/nejmoa040465
32 https://doi.org/10.1056/nejmoa041974
33 https://doi.org/10.1073/pnas.122233699
34 https://doi.org/10.1073/pnas.142103599
35 https://doi.org/10.1101/gr.078212.108
36 https://doi.org/10.1111/j.1365-2141.2007.06909.x
37 https://doi.org/10.1182/blood-2002-03-0772
38 https://doi.org/10.1182/blood-2005-08-3167
39 https://doi.org/10.1182/blood-2006-06-001149
40 https://doi.org/10.1182/blood-2007-03-081216
41 https://doi.org/10.1182/blood-2007-07-101394
42 https://doi.org/10.1182/blood-2007-09-113027
43 https://doi.org/10.1200/jco.2005.04.5450
44 https://doi.org/10.1371/journal.pbio.0050254
45 https://doi.org/10.3322/ca.2007.0010
46 https://doi.org/10.4161/cc.4.11.2174
47 schema:datePublished 2008-11
48 schema:datePublishedReg 2008-11-01
49 schema:description Acute myeloid leukaemia is a highly malignant haematopoietic tumour that affects about 13,000 adults in the United States each year. The treatment of this disease has changed little in the past two decades, because most of the genetic events that initiate the disease remain undiscovered. Whole-genome sequencing is now possible at a reasonable cost and timeframe to use this approach for the unbiased discovery of tumour-specific somatic mutations that alter the protein-coding genes. Here we present the results obtained from sequencing a typical acute myeloid leukaemia genome, and its matched normal counterpart obtained from the same patient's skin. We discovered ten genes with acquired mutations; two were previously described mutations that are thought to contribute to tumour progression, and eight were new mutations present in virtually all tumour cells at presentation and relapse, the function of which is not yet known. Our study establishes whole-genome sequencing as an unbiased method for discovering cancer-initiating mutations in previously unidentified genes that may respond to targeted therapies.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree true
53 schema:isPartOf N2c5a097f7ce64c44bd811cd245f542c3
54 Ne9349b6d0fb449869d60d415168f6d2b
55 sg:journal.1018957
56 schema:name DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
57 schema:pagination 66
58 schema:productId N0fcf38724c01491bbd933d1de48f5d29
59 N43d125b60d13483d8b110e62a389f19c
60 N4b1022ca7f8249cc8331154eac9c2e20
61 N556c546faaf64c22bb355434a1fae295
62 N6b6de46bca464eada8d693caed12ea42
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034796960
64 https://doi.org/10.1038/nature07485
65 schema:sdDatePublished 2019-04-10T12:59
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher N2fd9947af9cd4f7eb3ddb0ed210c5a69
68 schema:url https://www.nature.com/articles/nature07485
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N007dfbbbeda74edc96fb433c9f8463e7 rdf:first sg:person.01030001224.78
73 rdf:rest N06d5ff6e1fee4526b7590d2f891d835a
74 N024f914e09b24ffd83e4486f0fc3f882 schema:affiliation Na0a236b88fd740fa8dff1c9c4950274c
75 schema:familyName Conyers
76 schema:givenName Joshua
77 rdf:type schema:Person
78 N02e14164eaf04fc2a31094512b304790 schema:name The Genome Center at Washington University,
79 rdf:type schema:Organization
80 N03eb8fdae11f40c690b2468bc54a30fe rdf:first sg:person.0706035023.27
81 rdf:rest N706c65690a4d440db3b2eae5ddc10b89
82 N044a2a15578043cbb5178387dd3a4f87 rdf:first N1619040e29f143dabdb082fe1c2fa45c
83 rdf:rest N6fab3cba3ea14b4881012dd5b94c4394
84 N06d5ff6e1fee4526b7590d2f891d835a rdf:first sg:person.0626250070.02
85 rdf:rest N8fecad0ef4124f9993e079816aa3cd78
86 N0c93b9c361154147a859ecbe23621d21 rdf:first Na128c74094f640c1a8a004122745209c
87 rdf:rest Nb4ba7ccd1f95466a967432f77ccf38a5
88 N0cb16804d5684e6783246defba8e26df rdf:first N190cfadf2347454e81e03324cf84708e
89 rdf:rest N62b48507289d43fcadda9159b10801e6
90 N0fcf38724c01491bbd933d1de48f5d29 schema:name doi
91 schema:value 10.1038/nature07485
92 rdf:type schema:PropertyValue
93 N12a795e9efe94df2a7608fe9d76b7283 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Recurrence
95 rdf:type schema:DefinedTerm
96 N146cf5324b304511a0246e7cd4f6bb1c schema:name The Genome Center at Washington University,
97 rdf:type schema:Organization
98 N1619040e29f143dabdb082fe1c2fa45c schema:affiliation Nc416661f30464cc5a9441af0fabb479f
99 schema:familyName Pohl
100 schema:givenName Craig
101 rdf:type schema:Person
102 N16fb61fe8b634b1ea4c4b0e95a89eb2e rdf:first sg:person.01301532051.27
103 rdf:rest Ne105fea58b8a4c288012e8c4470668be
104 N180d190011ac4abea7394db7f0aa9892 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Skin
106 rdf:type schema:DefinedTerm
107 N190cfadf2347454e81e03324cf84708e schema:affiliation N5b6766c1138c4c7da03a78859a35fa36
108 schema:familyName Minx
109 schema:givenName Patrick
110 rdf:type schema:Person
111 N1d4d71e2b764498bbdfda5fdac4723a9 rdf:first sg:person.010365471537.46
112 rdf:rest N007dfbbbeda74edc96fb433c9f8463e7
113 N1e6ed93e468142efb65d40d708b34a87 schema:name The Genome Center at Washington University,
114 rdf:type schema:Organization
115 N2071da35c4ad4da5b60fd4e3029e948f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Mutagenesis, Insertional
117 rdf:type schema:DefinedTerm
118 N20d1e7ac99d247c08dcc39a9ccaa5824 rdf:first sg:person.07652030364.52
119 rdf:rest N8c8bc9e815024154affe51d0b03b20fb
120 N2483bb8d54434433bf7512f22ceaa202 rdf:first N26f831ecee924433a5ac261943c51c8c
121 rdf:rest N044a2a15578043cbb5178387dd3a4f87
122 N26f831ecee924433a5ac261943c51c8c schema:affiliation N49ecc2277d5a4aa2be573a9dcd12147e
123 schema:familyName Koboldt
124 schema:givenName Dan C.
125 rdf:type schema:Person
126 N2768213a41824e59b933f006f8a9f293 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Leukemia, Myeloid, Acute
128 rdf:type schema:DefinedTerm
129 N2acddd0572a24d3080fe4a39f37d44eb rdf:first N4f3aeb71ddfd4c66bbaa64889df07a60
130 rdf:rest Nbb8ce67fc2a244dd84b1581e3f7cec6e
131 N2c5a097f7ce64c44bd811cd245f542c3 schema:issueNumber 7218
132 rdf:type schema:PublicationIssue
133 N2ce770e26e6949d390d7ece7bbca0afa schema:name Department of Genetics,
134 The Genome Center at Washington University,
135 rdf:type schema:Organization
136 N2fd9947af9cd4f7eb3ddb0ed210c5a69 schema:name Springer Nature - SN SciGraph project
137 rdf:type schema:Organization
138 N306f223eea9f4677810436526e2937ed schema:name Department of Medicine,
139 rdf:type schema:Organization
140 N307707b093a24a0ebe2b9881d42fe3f4 rdf:first sg:person.0755514036.46
141 rdf:rest N8fd76f49bdcd47849a88928bd95db0a6
142 N32561174651b435cb45a44e89226869a schema:name The Genome Center at Washington University,
143 rdf:type schema:Organization
144 N3388141373dd4b0eaa22de4db58fe8eb schema:name The Genome Center at Washington University,
145 rdf:type schema:Organization
146 N34d4ce9977104147bd8e9ebac7fb77e5 schema:affiliation N306f223eea9f4677810436526e2937ed
147 schema:familyName Zhao
148 schema:givenName Yu
149 rdf:type schema:Person
150 N3766423dbd3c432db77bb0500c522a64 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Gene Expression Regulation, Neoplastic
152 rdf:type schema:DefinedTerm
153 N3a2a41e6cc774b64892befe980a6c333 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
154 schema:familyName Ley
155 schema:givenName Timothy J.
156 rdf:type schema:Person
157 N3a6dd2cca1c742bea92573ccd6f1072a rdf:first sg:person.01051055051.29
158 rdf:rest N03eb8fdae11f40c690b2468bc54a30fe
159 N3cedab9b41074503b1ee03cb0f6fe7ac schema:name The Genome Center at Washington University,
160 rdf:type schema:Organization
161 N43d125b60d13483d8b110e62a389f19c schema:name pubmed_id
162 schema:value 18987736
163 rdf:type schema:PropertyValue
164 N459182c846b94ff9b3352ce49d87cadd schema:affiliation Ndcb02a18e36345efb9c5ac6d5d158ff2
165 schema:familyName Abbott
166 schema:givenName Rachel
167 rdf:type schema:Person
168 N477f6755f56d4cfb86ce525c4ea66a33 rdf:first sg:person.011243173122.25
169 rdf:rest N8c21cde0223145229c11b3a440a6e611
170 N48689ed566804884a1585966e3b7a12d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Sequence Analysis, DNA
172 rdf:type schema:DefinedTerm
173 N49ecc2277d5a4aa2be573a9dcd12147e schema:name The Genome Center at Washington University,
174 rdf:type schema:Organization
175 N4b1022ca7f8249cc8331154eac9c2e20 schema:name readcube_id
176 schema:value a5c286f8c234e23133a1fe0f8b12108876603d3172332442ec911b92c5203646
177 rdf:type schema:PropertyValue
178 N4c944e2ccdc54757abaf19fa9acdb551 rdf:first sg:person.0730273326.07
179 rdf:rest Ncb82ca25c9f140e3a67aa6932c9daee8
180 N4edcfa51412c4460a4f0b14b572bb90b rdf:first sg:person.01164172261.53
181 rdf:rest N2acddd0572a24d3080fe4a39f37d44eb
182 N4f3aeb71ddfd4c66bbaa64889df07a60 schema:affiliation N146cf5324b304511a0246e7cd4f6bb1c
183 schema:familyName Chen
184 schema:givenName Ken
185 rdf:type schema:Person
186 N4fe1ca1fe6c849f5b7097101979f25d4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Sequence Deletion
188 rdf:type schema:DefinedTerm
189 N52c01d8613124bb1a3fad4e579909e45 schema:affiliation N991e66f1d67c47ffa734c9f3ab2794c6
190 schema:familyName Fulton
191 schema:givenName Bob
192 rdf:type schema:Person
193 N54b04655ec8c4df3bed07323fb87f06e rdf:first N459182c846b94ff9b3352ce49d87cadd
194 rdf:rest Nb502f8301a3f4c36a2524fa45a61ccf6
195 N556c546faaf64c22bb355434a1fae295 schema:name dimensions_id
196 schema:value pub.1034796960
197 rdf:type schema:PropertyValue
198 N5b6766c1138c4c7da03a78859a35fa36 schema:name The Genome Center at Washington University,
199 rdf:type schema:Organization
200 N5d9e4125ae164323936ff03ac6262b10 schema:name The Genome Center at Washington University,
201 rdf:type schema:Organization
202 N62b48507289d43fcadda9159b10801e6 rdf:first Nf6b07dce3aaa46f4b341b880d4394caf
203 rdf:rest Ne795c18142cc4f59a780f2e0e241841d
204 N6389aec4f7f6447d80e0ef199837e872 schema:name Department of Genetics,
205 The Genome Center at Washington University,
206 rdf:type schema:Organization
207 N6aa8a15fa21a43fe8ff72224e4aefd36 rdf:first sg:person.01304651323.65
208 rdf:rest N82820c42e64f40d1b9a5f9105171d869
209 N6b6de46bca464eada8d693caed12ea42 schema:name nlm_unique_id
210 schema:value 0410462
211 rdf:type schema:PropertyValue
212 N6e0e383cc4e749d08fa7c33a1d4591ca rdf:first N9bc4c7cf58e9483a8b7408edf24a29cd
213 rdf:rest N4c944e2ccdc54757abaf19fa9acdb551
214 N6fab3cba3ea14b4881012dd5b94c4394 rdf:first Nec08bb2efea1418eafcb7de212130e5a
215 rdf:rest N84b960e07d794ce59ac9dab8610ce26e
216 N706c65690a4d440db3b2eae5ddc10b89 rdf:first sg:person.0707031611.51
217 rdf:rest N477f6755f56d4cfb86ce525c4ea66a33
218 N710597d17ed64d0285780db083f292dd schema:name The Genome Center at Washington University,
219 rdf:type schema:Organization
220 N72a390f4efb847849976eea6a9904307 rdf:first sg:person.0754602624.59
221 rdf:rest N3a6dd2cca1c742bea92573ccd6f1072a
222 N77858362c37942ac9d013ed7334fb13e rdf:first sg:person.01257441450.64
223 rdf:rest N935f39a35283423c8e7cfb751a6c50e3
224 N791632aaef364820a16c454b9cd55bc4 rdf:first Nfa620415ec554dc8af80a790265f7e14
225 rdf:rest N0cb16804d5684e6783246defba8e26df
226 N7d00aa4c1da14e2498652ea58df78f18 rdf:first Naa6ef050c0e74fd483d22b22f7defcdd
227 rdf:rest Nc919f0884b124300a557654763d7053f
228 N7ec3ae6f33834eb5a032301e11184cc0 schema:name The Genome Center at Washington University,
229 rdf:type schema:Organization
230 N80d915f1080043549b2c59d2f232993f schema:name The Genome Center at Washington University,
231 rdf:type schema:Organization
232 N82820c42e64f40d1b9a5f9105171d869 rdf:first sg:person.0744070252.41
233 rdf:rest N77858362c37942ac9d013ed7334fb13e
234 N83169df0899d4608a608076bb764b8fd schema:name The Genome Center at Washington University,
235 rdf:type schema:Organization
236 N837df5a4ddbb4e1ea8a2589bde8db482 schema:name The Genome Center at Washington University,
237 rdf:type schema:Organization
238 N842ce2c03c514db98435cc051c6f0d1d rdf:first sg:person.01347645251.52
239 rdf:rest N307707b093a24a0ebe2b9881d42fe3f4
240 N84b960e07d794ce59ac9dab8610ce26e rdf:first Nb9b2ce52cd304903992517856d3513d8
241 rdf:rest N6e0e383cc4e749d08fa7c33a1d4591ca
242 N8c21cde0223145229c11b3a440a6e611 rdf:first Ndd5090c9cfca464382d861cc4dbd659d
243 rdf:rest Nd1393817a295478bbe5e4d3802de13b0
244 N8c8bc9e815024154affe51d0b03b20fb rdf:first sg:person.0726230426.05
245 rdf:rest N16fb61fe8b634b1ea4c4b0e95a89eb2e
246 N8fd76f49bdcd47849a88928bd95db0a6 rdf:first sg:person.013076541047.38
247 rdf:rest rdf:nil
248 N8fe090a11b5e4cdea06b5f3245307bf8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
249 schema:name Genome, Human
250 rdf:type schema:DefinedTerm
251 N8fecad0ef4124f9993e079816aa3cd78 rdf:first sg:person.01325554650.54
252 rdf:rest Ne4606009968e43a184aff0cfdfbcc4ce
253 N935f39a35283423c8e7cfb751a6c50e3 rdf:first Na6c9c4a0e55d4712a80fe45f706dc5b8
254 rdf:rest N54b04655ec8c4df3bed07323fb87f06e
255 N989eeca7929a45d0b138d0851604673a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
256 schema:name Genomics
257 rdf:type schema:DefinedTerm
258 N991e66f1d67c47ffa734c9f3ab2794c6 schema:name The Genome Center at Washington University,
259 rdf:type schema:Organization
260 N9ba9d051fc244df4a5aed5774d5acfd1 schema:name The Genome Center at Washington University,
261 rdf:type schema:Organization
262 N9bc4c7cf58e9483a8b7408edf24a29cd schema:affiliation Nb212d09c0583434e8bf88f84b91d3b94
263 schema:familyName Abbott
264 schema:givenName Scott
265 rdf:type schema:Person
266 Na0a236b88fd740fa8dff1c9c4950274c schema:name The Genome Center at Washington University,
267 rdf:type schema:Organization
268 Na128c74094f640c1a8a004122745209c schema:affiliation N710597d17ed64d0285780db083f292dd
269 schema:familyName Sander
270 schema:givenName Nathan
271 rdf:type schema:Person
272 Na4f59a2824f9443ab7d1b53afa5826dd rdf:first N3a2a41e6cc774b64892befe980a6c333
273 rdf:rest Nefa62dfac15d4f84a8a576e7c1190090
274 Na6c9c4a0e55d4712a80fe45f706dc5b8 schema:affiliation N9ba9d051fc244df4a5aed5774d5acfd1
275 schema:familyName Cook
276 schema:givenName Lisa
277 rdf:type schema:Person
278 Naa6ef050c0e74fd483d22b22f7defcdd schema:affiliation N2ce770e26e6949d390d7ece7bbca0afa
279 schema:familyName Ding
280 schema:givenName Li
281 rdf:type schema:Person
282 Nb1b6a3398fdf454bb3ccd377d2b16be5 schema:name The Genome Center at Washington University,
283 rdf:type schema:Organization
284 Nb212d09c0583434e8bf88f84b91d3b94 schema:name The Genome Center at Washington University,
285 rdf:type schema:Organization
286 Nb4ba7ccd1f95466a967432f77ccf38a5 rdf:first Ncde3fa5fc1974642b3bcf890f43bf2f4
287 rdf:rest N791632aaef364820a16c454b9cd55bc4
288 Nb502f8301a3f4c36a2524fa45a61ccf6 rdf:first sg:person.01053604761.84
289 rdf:rest N2483bb8d54434433bf7512f22ceaa202
290 Nb67851007f6d46c789cda943c5617c45 schema:name The Genome Center at Washington University,
291 rdf:type schema:Organization
292 Nb75b73d57a48403d9e88aa0e2a939e7e schema:name Department of Medicine,
293 rdf:type schema:Organization
294 Nb76fd9193b0048adab6c4722cfb35860 schema:affiliation N7ec3ae6f33834eb5a032301e11184cc0
295 schema:familyName Chinwalla
296 schema:givenName Asif
297 rdf:type schema:Person
298 Nb9b2ce52cd304903992517856d3513d8 schema:affiliation N837df5a4ddbb4e1ea8a2589bde8db482
299 schema:familyName Hawkins
300 schema:givenName Amy
301 rdf:type schema:Person
302 Nbac8cb1d2ce94f109e44561e6847accf schema:name Department of Pathology and Immunology,
303 rdf:type schema:Organization
304 Nbad4fb1b785a412ca0b346fb2bd6e3ac schema:name Department of Genetics,
305 The Genome Center at Washington University,
306 rdf:type schema:Organization
307 Nbb8ce67fc2a244dd84b1581e3f7cec6e rdf:first sg:person.01300420661.22
308 rdf:rest N6aa8a15fa21a43fe8ff72224e4aefd36
309 Nc34d88d90fb847a482a5eac92b11b9b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
310 schema:name Mutation
311 rdf:type schema:DefinedTerm
312 Nc416661f30464cc5a9441af0fabb479f schema:name The Genome Center at Washington University,
313 rdf:type schema:Organization
314 Nc6b2d619386c40bd9201d80d80bde22f schema:name The Genome Center at Washington University,
315 rdf:type schema:Organization
316 Nc79d2cca0e384127886119372ba2c0fc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
317 schema:name Polymorphism, Single Nucleotide
318 rdf:type schema:DefinedTerm
319 Nc919f0884b124300a557654763d7053f rdf:first N52c01d8613124bb1a3fad4e579909e45
320 rdf:rest N4edcfa51412c4460a4f0b14b572bb90b
321 Ncb82ca25c9f140e3a67aa6932c9daee8 rdf:first sg:person.01014313442.46
322 rdf:rest Ne1108bd17fe34752b6a87a8b2cec928c
323 Ncde3fa5fc1974642b3bcf890f43bf2f4 schema:affiliation N02e14164eaf04fc2a31094512b304790
324 schema:familyName Shi
325 schema:givenName Xiaoqi
326 rdf:type schema:Person
327 Nd1393817a295478bbe5e4d3802de13b0 rdf:first sg:person.0664667051.13
328 rdf:rest Ne2e8eb01cd5644299f17fa4793de3efb
329 Nd6b16099a0eb469f9e2e5bbdf1080f1a schema:name The Genome Center at Washington University,
330 rdf:type schema:Organization
331 Nd7ba0128c84543dfb7e22986a9a07986 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
332 schema:name Humans
333 rdf:type schema:DefinedTerm
334 Ndcb02a18e36345efb9c5ac6d5d158ff2 schema:name The Genome Center at Washington University,
335 rdf:type schema:Organization
336 Ndd5090c9cfca464382d861cc4dbd659d schema:affiliation Nf52040e8384842ecb1c50a4a76213716
337 schema:familyName Baty
338 schema:givenName Jack
339 rdf:type schema:Person
340 Ne105fea58b8a4c288012e8c4470668be rdf:first sg:person.016375226437.33
341 rdf:rest N842ce2c03c514db98435cc051c6f0d1d
342 Ne1108bd17fe34752b6a87a8b2cec928c rdf:first sg:person.01344004151.06
343 rdf:rest N1d4d71e2b764498bbdfda5fdac4723a9
344 Ne2e8eb01cd5644299f17fa4793de3efb rdf:first sg:person.01250443136.44
345 rdf:rest N20d1e7ac99d247c08dcc39a9ccaa5824
346 Ne4606009968e43a184aff0cfdfbcc4ce rdf:first N024f914e09b24ffd83e4486f0fc3f882
347 rdf:rest N0c93b9c361154147a859ecbe23621d21
348 Ne4d1aa78730541268c650395ea92d473 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
349 schema:name Disease Progression
350 rdf:type schema:DefinedTerm
351 Ne63c54cb97df4129bc67d93c39287a95 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
352 schema:name Gene Expression Profiling
353 rdf:type schema:DefinedTerm
354 Ne795c18142cc4f59a780f2e0e241841d rdf:first Nb76fd9193b0048adab6c4722cfb35860
355 rdf:rest Nefbf01f2f92e4a8a9fa7d3d067aba877
356 Ne9349b6d0fb449869d60d415168f6d2b schema:volumeNumber 456
357 rdf:type schema:PublicationVolume
358 Nebc36ba625d04d8bb44f8874343353d3 schema:name The Genome Center at Washington University,
359 rdf:type schema:Organization
360 Nec08bb2efea1418eafcb7de212130e5a schema:affiliation Nebc36ba625d04d8bb44f8874343353d3
361 schema:familyName Smith
362 schema:givenName Scott
363 rdf:type schema:Person
364 Nefa62dfac15d4f84a8a576e7c1190090 rdf:first sg:person.01023627236.33
365 rdf:rest N7d00aa4c1da14e2498652ea58df78f18
366 Nefbf01f2f92e4a8a9fa7d3d067aba877 rdf:first N34d4ce9977104147bd8e9ebac7fb77e5
367 rdf:rest N72a390f4efb847849976eea6a9904307
368 Nf52040e8384842ecb1c50a4a76213716 schema:name Division of Biostatistics, and,
369 rdf:type schema:Organization
370 Nf6b07dce3aaa46f4b341b880d4394caf schema:affiliation https://www.grid.ac/institutes/grid.34477.33
371 schema:familyName Gordon
372 schema:givenName David
373 rdf:type schema:Person
374 Nfa620415ec554dc8af80a790265f7e14 schema:affiliation Nc6b2d619386c40bd9201d80d80bde22f
375 schema:familyName Osborne
376 schema:givenName John R.
377 rdf:type schema:Person
378 Nfaf5894787b6429fa70f793b8a191bcb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
379 schema:name Case-Control Studies
380 rdf:type schema:DefinedTerm
381 Nfbf084fbaec545cab42e78e09362bef1 schema:name The Genome Center at Washington University,
382 rdf:type schema:Organization
383 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
384 schema:name Medical and Health Sciences
385 rdf:type schema:DefinedTerm
386 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
387 schema:name Oncology and Carcinogenesis
388 rdf:type schema:DefinedTerm
389 sg:grant.2699308 http://pending.schema.org/fundedItem sg:pub.10.1038/nature07485
390 rdf:type schema:MonetaryGrant
391 sg:journal.1018957 schema:issn 0090-0028
392 1476-4687
393 schema:name Nature
394 rdf:type schema:Periodical
395 sg:person.01014313442.46 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
396 schema:familyName Hillier
397 schema:givenName LaDeana W.
398 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014313442.46
399 rdf:type schema:Person
400 sg:person.01023627236.33 schema:affiliation N6389aec4f7f6447d80e0ef199837e872
401 schema:familyName Mardis
402 schema:givenName Elaine R.
403 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023627236.33
404 rdf:type schema:Person
405 sg:person.01030001224.78 schema:affiliation Nbad4fb1b785a412ca0b346fb2bd6e3ac
406 schema:familyName Magrini
407 schema:givenName Vincent
408 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030001224.78
409 rdf:type schema:Person
410 sg:person.010365471537.46 schema:affiliation N83169df0899d4608a608076bb764b8fd
411 schema:familyName Fulton
412 schema:givenName Lucinda
413 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010365471537.46
414 rdf:type schema:Person
415 sg:person.01051055051.29 schema:affiliation Nbac8cb1d2ce94f109e44561e6847accf
416 schema:familyName Payton
417 schema:givenName Jacqueline E.
418 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051055051.29
419 rdf:type schema:Person
420 sg:person.01053604761.84 schema:affiliation N80d915f1080043549b2c59d2f232993f
421 schema:familyName Larson
422 schema:givenName David E.
423 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053604761.84
424 rdf:type schema:Person
425 sg:person.011243173122.25 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
426 schema:familyName Watson
427 schema:givenName Mark
428 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011243173122.25
429 rdf:type schema:Person
430 sg:person.01164172261.53 schema:affiliation Nfbf084fbaec545cab42e78e09362bef1
431 schema:familyName McLellan
432 schema:givenName Michael D.
433 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01164172261.53
434 rdf:type schema:Person
435 sg:person.01250443136.44 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
436 schema:familyName Heath
437 schema:givenName Sharon
438 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250443136.44
439 rdf:type schema:Person
440 sg:person.01257441450.64 schema:affiliation N5d9e4125ae164323936ff03ac6262b10
441 schema:familyName Hickenbotham
442 schema:givenName Matthew
443 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257441450.64
444 rdf:type schema:Person
445 sg:person.01300420661.22 schema:affiliation N3388141373dd4b0eaa22de4db58fe8eb
446 schema:familyName Dooling
447 schema:givenName David
448 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300420661.22
449 rdf:type schema:Person
450 sg:person.01301532051.27 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
451 schema:familyName Walter
452 schema:givenName Matthew J.
453 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301532051.27
454 rdf:type schema:Person
455 sg:person.01304651323.65 schema:affiliation N1e6ed93e468142efb65d40d708b34a87
456 schema:familyName Dunford-Shore
457 schema:givenName Brian H.
458 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304651323.65
459 rdf:type schema:Person
460 sg:person.013076541047.38 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
461 schema:familyName Wilson
462 schema:givenName Richard K.
463 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013076541047.38
464 rdf:type schema:Person
465 sg:person.01325554650.54 schema:affiliation N32561174651b435cb45a44e89226869a
466 schema:familyName Glasscock
467 schema:givenName Jarret
468 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325554650.54
469 rdf:type schema:Person
470 sg:person.01344004151.06 schema:affiliation N3cedab9b41074503b1ee03cb0f6fe7ac
471 schema:familyName Miner
472 schema:givenName Tracie
473 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344004151.06
474 rdf:type schema:Person
475 sg:person.01347645251.52 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
476 schema:familyName Graubert
477 schema:givenName Timothy A.
478 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347645251.52
479 rdf:type schema:Person
480 sg:person.016375226437.33 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
481 schema:familyName Link
482 schema:givenName Daniel C.
483 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016375226437.33
484 rdf:type schema:Person
485 sg:person.0626250070.02 schema:affiliation Nb1b6a3398fdf454bb3ccd377d2b16be5
486 schema:familyName Wylie
487 schema:givenName Todd
488 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626250070.02
489 rdf:type schema:Person
490 sg:person.0664667051.13 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
491 schema:familyName Ivanovich
492 schema:givenName Jennifer
493 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664667051.13
494 rdf:type schema:Person
495 sg:person.0706035023.27 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
496 schema:familyName Westervelt
497 schema:givenName Peter
498 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0706035023.27
499 rdf:type schema:Person
500 sg:person.0707031611.51 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
501 schema:familyName Tomasson
502 schema:givenName Michael H.
503 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707031611.51
504 rdf:type schema:Person
505 sg:person.0726230426.05 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
506 schema:familyName Nagarajan
507 schema:givenName Rakesh
508 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726230426.05
509 rdf:type schema:Person
510 sg:person.0730273326.07 schema:affiliation Nd6b16099a0eb469f9e2e5bbdf1080f1a
511 schema:familyName Locke
512 schema:givenName Devin
513 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730273326.07
514 rdf:type schema:Person
515 sg:person.0744070252.41 schema:affiliation Nb67851007f6d46c789cda943c5617c45
516 schema:familyName McGrath
517 schema:givenName Sean
518 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744070252.41
519 rdf:type schema:Person
520 sg:person.0754602624.59 schema:affiliation Nb75b73d57a48403d9e88aa0e2a939e7e
521 schema:familyName Ries
522 schema:givenName Rhonda E.
523 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754602624.59
524 rdf:type schema:Person
525 sg:person.0755514036.46 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
526 schema:familyName DiPersio
527 schema:givenName John F.
528 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0755514036.46
529 rdf:type schema:Person
530 sg:person.07652030364.52 schema:affiliation https://www.grid.ac/institutes/grid.4367.6
531 schema:familyName Shannon
532 schema:givenName William D.
533 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07652030364.52
534 rdf:type schema:Person
535 sg:pub.10.1038/nature05690 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014017146
536 https://doi.org/10.1038/nature05690
537 rdf:type schema:CreativeWork
538 sg:pub.10.1038/nature06866 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052983633
539 https://doi.org/10.1038/nature06866
540 rdf:type schema:CreativeWork
541 sg:pub.10.1038/nature06884 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047672670
542 https://doi.org/10.1038/nature06884
543 rdf:type schema:CreativeWork
544 sg:pub.10.1038/nmeth.1179 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001773338
545 https://doi.org/10.1038/nmeth.1179
546 rdf:type schema:CreativeWork
547 sg:pub.10.1038/sj.leu.2403099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029950764
548 https://doi.org/10.1038/sj.leu.2403099
549 rdf:type schema:CreativeWork
550 sg:pub.10.1038/sj.leu.2404145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025528247
551 https://doi.org/10.1038/sj.leu.2404145
552 rdf:type schema:CreativeWork
553 sg:pub.10.1186/1471-2105-9-239 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040243916
554 https://doi.org/10.1186/1471-2105-9-239
555 rdf:type schema:CreativeWork
556 https://app.dimensions.ai/details/publication/pub.1077003884 schema:CreativeWork
557 https://app.dimensions.ai/details/publication/pub.1083319627 schema:CreativeWork
558 https://doi.org/10.1016/j.ccr.2007.11.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021461434
559 rdf:type schema:CreativeWork
560 https://doi.org/10.1016/s0268-960x(03)00040-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004829505
561 rdf:type schema:CreativeWork
562 https://doi.org/10.1056/nejmoa031046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029492007
563 rdf:type schema:CreativeWork
564 https://doi.org/10.1056/nejmoa040465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027799720
565 rdf:type schema:CreativeWork
566 https://doi.org/10.1056/nejmoa041974 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020502159
567 rdf:type schema:CreativeWork
568 https://doi.org/10.1073/pnas.122233699 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003891362
569 rdf:type schema:CreativeWork
570 https://doi.org/10.1073/pnas.142103599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029045939
571 rdf:type schema:CreativeWork
572 https://doi.org/10.1101/gr.078212.108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047542880
573 rdf:type schema:CreativeWork
574 https://doi.org/10.1111/j.1365-2141.2007.06909.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1023895017
575 rdf:type schema:CreativeWork
576 https://doi.org/10.1182/blood-2002-03-0772 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024049275
577 rdf:type schema:CreativeWork
578 https://doi.org/10.1182/blood-2005-08-3167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001126578
579 rdf:type schema:CreativeWork
580 https://doi.org/10.1182/blood-2006-06-001149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005044116
581 rdf:type schema:CreativeWork
582 https://doi.org/10.1182/blood-2007-03-081216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046183450
583 rdf:type schema:CreativeWork
584 https://doi.org/10.1182/blood-2007-07-101394 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020817577
585 rdf:type schema:CreativeWork
586 https://doi.org/10.1182/blood-2007-09-113027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007947126
587 rdf:type schema:CreativeWork
588 https://doi.org/10.1200/jco.2005.04.5450 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000372533
589 rdf:type schema:CreativeWork
590 https://doi.org/10.1371/journal.pbio.0050254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028942453
591 rdf:type schema:CreativeWork
592 https://doi.org/10.3322/ca.2007.0010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052065817
593 rdf:type schema:CreativeWork
594 https://doi.org/10.4161/cc.4.11.2174 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072298154
595 rdf:type schema:CreativeWork
596 https://www.grid.ac/institutes/grid.34477.33 schema:alternateName University of Washington
597 schema:name Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA
598 The Genome Center at Washington University,
599 rdf:type schema:Organization
600 https://www.grid.ac/institutes/grid.4367.6 schema:alternateName Washington University in St. Louis
601 schema:name Department of Genetics,
602 Department of Medicine,
603 Department of Pathology and Immunology,
604 Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63108, USA
605 Siteman Cancer Center,
606 The Genome Center at Washington University,
607 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...