Neurite arborization and mosaic spacing in the mouse retina require DSCAM View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-01

AUTHORS

Peter G. Fuerst, Amane Koizumi, Richard H. Masland, Robert W. Burgess

ABSTRACT

Making connectionsDowns syndrome cell adhesion molecules (Dscams) are adhesion molecules of the immunoglolulin superfamily. Drosophila Dscams have been implicated in the organization of neural connectivity, but little is known about the functions of the closely related molecules in vertebrates. Masahito Yamagata and Joshua Sanes now demonstrate a role for Dscam and DscamL in patterning of lamina-specific connections in the chick retina. Two other adhesion molecules, called Sidekick-1 and Sidekick-2, act in a similar way. These molecules are widely distributed in the nervous system and may be part of an 'adhesive code' that patterns neural connections in the brain. Further evidence for the importance of Dscams in vertebrate neural patterning comes from Fuerst et al., who identify a role for DSCAM in establishing neural circuits in the retina of mice. More... »

PAGES

470-474

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature06514

DOI

http://dx.doi.org/10.1038/nature06514

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047861993

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18216855


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amacrine Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Adhesion Molecules", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Movement", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Deletion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurites", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA Stability", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retina", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "The Jackson Laboratory, Bar Harbor, Maine 04609, USA", 
          "id": "http://www.grid.ac/institutes/grid.249880.f", 
          "name": [
            "The Jackson Laboratory, Bar Harbor, Maine 04609, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fuerst", 
        "givenName": "Peter G.", 
        "id": "sg:person.0576727350.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0576727350.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Present address: National Institute for Physiological Sciences, 38 Nishigonaka, Myodaiji, Okazaki, 444-8585, Japan.", 
          "id": "http://www.grid.ac/institutes/grid.467811.d", 
          "name": [
            "Massachusetts General Hospital, Boston, Massachusetts 02114, USA", 
            "Present address: National Institute for Physiological Sciences, 38 Nishigonaka, Myodaiji, Okazaki, 444-8585, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koizumi", 
        "givenName": "Amane", 
        "id": "sg:person.0722261057.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722261057.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Massachusetts General Hospital, Boston, Massachusetts 02114, USA", 
          "id": "http://www.grid.ac/institutes/grid.32224.35", 
          "name": [
            "Massachusetts General Hospital, Boston, Massachusetts 02114, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Masland", 
        "givenName": "Richard H.", 
        "id": "sg:person.01036507457.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036507457.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Jackson Laboratory, Bar Harbor, Maine 04609, USA", 
          "id": "http://www.grid.ac/institutes/grid.249880.f", 
          "name": [
            "The Jackson Laboratory, Bar Harbor, Maine 04609, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Burgess", 
        "givenName": "Robert W.", 
        "id": "sg:person.01172146666.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172146666.60"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/nature06469", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049991249", 
          "https://doi.org/10.1038/nature06469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06147", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032360637", 
          "https://doi.org/10.1038/nature06147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature05855", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040854933", 
          "https://doi.org/10.1038/nature05855"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047549634", 
          "https://doi.org/10.1038/ng1299"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053541205", 
          "https://doi.org/10.1038/nature06099"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-01", 
    "datePublishedReg": "2008-01-01", 
    "description": "Making connectionsDowns syndrome cell adhesion molecules (Dscams) are adhesion molecules of the immunoglolulin superfamily. Drosophila Dscams have been implicated in the organization of neural connectivity, but little is known about the functions of the closely related molecules in vertebrates. Masahito Yamagata and Joshua Sanes now demonstrate a role for Dscam and DscamL in patterning of lamina-specific connections in the chick retina. Two other adhesion molecules, called Sidekick-1 and Sidekick-2, act in a similar way. These molecules are widely distributed in the nervous system and may be part of an 'adhesive code' that patterns neural connections in the brain. Further evidence for the importance of Dscams in vertebrate neural patterning comes from Fuerst et al., who identify a role for DSCAM in establishing neural circuits in the retina of mice.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/nature06514", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2378031", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2574013", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7177", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "451"
      }
    ], 
    "keywords": [
      "vertebrate neural patterning", 
      "syndrome cell adhesion molecule", 
      "adhesion molecules", 
      "Drosophila Dscam", 
      "adhesive code", 
      "neural patterning", 
      "sidekick-1", 
      "cell adhesion molecule", 
      "Dscam", 
      "lamina-specific connections", 
      "neurite arborization", 
      "mouse retina", 
      "patterning", 
      "mosaic spacing", 
      "related molecules", 
      "vertebrates", 
      "neural circuits", 
      "chick retina", 
      "molecules", 
      "nervous system", 
      "retina of mice", 
      "further evidence", 
      "role", 
      "similar way", 
      "retina", 
      "neural connectivity", 
      "mice", 
      "neural connections", 
      "function", 
      "arborization", 
      "evidence", 
      "importance", 
      "brain", 
      "connectivity", 
      "organization", 
      "Yamagata", 
      "part", 
      "system", 
      "connection", 
      "et al", 
      "SANE", 
      "way", 
      "spacing", 
      "code", 
      "circuit", 
      "al"
    ], 
    "name": "Neurite arborization and mosaic spacing in the mouse retina require DSCAM", 
    "pagination": "470-474", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1047861993"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature06514"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18216855"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature06514", 
      "https://app.dimensions.ai/details/publication/pub.1047861993"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:27", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_473.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/nature06514"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature06514'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature06514'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature06514'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature06514'


 

This table displays all metadata directly associated to this object as RDF triples.

199 TRIPLES      21 PREDICATES      87 URIs      74 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature06514 schema:about N310e0d7b9bef4b9189c2d63679c56850
2 N386ed6a9ab1c4c7b9413a0539ee897e9
3 N4fc45ad0636746f1911d5ca4a1a2e549
4 N5b0622a65a16474f91c2ebe804a6ab27
5 Naa8fd31a90d444f3b31e3965253a0c4d
6 Nae42e4ff2c33454897da3522175a738d
7 Ndb96a730717d4530ac60b4b04f956302
8 Ne08fd193188a4f07a12223f5dbe60a2d
9 Ne9411a1cac044fdcb52daf5e055991e6
10 Nec5ae2c1532a4419b154f9e58185bacc
11 anzsrc-for:11
12 anzsrc-for:1109
13 schema:author Nd057d92afd4e414c961ef4e19e826825
14 schema:citation sg:pub.10.1038/nature05855
15 sg:pub.10.1038/nature06099
16 sg:pub.10.1038/nature06147
17 sg:pub.10.1038/nature06469
18 sg:pub.10.1038/ng1299
19 schema:datePublished 2008-01
20 schema:datePublishedReg 2008-01-01
21 schema:description Making connectionsDowns syndrome cell adhesion molecules (Dscams) are adhesion molecules of the immunoglolulin superfamily. Drosophila Dscams have been implicated in the organization of neural connectivity, but little is known about the functions of the closely related molecules in vertebrates. Masahito Yamagata and Joshua Sanes now demonstrate a role for Dscam and DscamL in patterning of lamina-specific connections in the chick retina. Two other adhesion molecules, called Sidekick-1 and Sidekick-2, act in a similar way. These molecules are widely distributed in the nervous system and may be part of an 'adhesive code' that patterns neural connections in the brain. Further evidence for the importance of Dscams in vertebrate neural patterning comes from Fuerst et al., who identify a role for DSCAM in establishing neural circuits in the retina of mice.
22 schema:genre article
23 schema:isAccessibleForFree true
24 schema:isPartOf Nbab3b9362f4440fab0b040f8b51be374
25 Nfc06e9a92cbf4c62abe9756eb1816b0a
26 sg:journal.1018957
27 schema:keywords Drosophila Dscam
28 Dscam
29 SANE
30 Yamagata
31 adhesion molecules
32 adhesive code
33 al
34 arborization
35 brain
36 cell adhesion molecule
37 chick retina
38 circuit
39 code
40 connection
41 connectivity
42 et al
43 evidence
44 function
45 further evidence
46 importance
47 lamina-specific connections
48 mice
49 molecules
50 mosaic spacing
51 mouse retina
52 nervous system
53 neural circuits
54 neural connections
55 neural connectivity
56 neural patterning
57 neurite arborization
58 organization
59 part
60 patterning
61 related molecules
62 retina
63 retina of mice
64 role
65 sidekick-1
66 similar way
67 spacing
68 syndrome cell adhesion molecule
69 system
70 vertebrate neural patterning
71 vertebrates
72 way
73 schema:name Neurite arborization and mosaic spacing in the mouse retina require DSCAM
74 schema:pagination 470-474
75 schema:productId N8c0848656b9c4e84b33246b3d1456547
76 N98a717e6f43d42cca3a4fb44e1e5b213
77 Ndb390d42cbaf4f129d87ea5a6c5141ac
78 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047861993
79 https://doi.org/10.1038/nature06514
80 schema:sdDatePublished 2022-12-01T06:27
81 schema:sdLicense https://scigraph.springernature.com/explorer/license/
82 schema:sdPublisher N29371b65897142ebb5e14698d002bab4
83 schema:url https://doi.org/10.1038/nature06514
84 sgo:license sg:explorer/license/
85 sgo:sdDataset articles
86 rdf:type schema:ScholarlyArticle
87 N29371b65897142ebb5e14698d002bab4 schema:name Springer Nature - SN SciGraph project
88 rdf:type schema:Organization
89 N310e0d7b9bef4b9189c2d63679c56850 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name RNA Stability
91 rdf:type schema:DefinedTerm
92 N386ed6a9ab1c4c7b9413a0539ee897e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Amacrine Cells
94 rdf:type schema:DefinedTerm
95 N4fc45ad0636746f1911d5ca4a1a2e549 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Neurites
97 rdf:type schema:DefinedTerm
98 N5b0622a65a16474f91c2ebe804a6ab27 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Cell Movement
100 rdf:type schema:DefinedTerm
101 N6902e16ae9894298a94888d12aca7706 rdf:first sg:person.01036507457.01
102 rdf:rest Nbf44b63b9a484de389df6f47f8ce3821
103 N8c0848656b9c4e84b33246b3d1456547 schema:name doi
104 schema:value 10.1038/nature06514
105 rdf:type schema:PropertyValue
106 N98a717e6f43d42cca3a4fb44e1e5b213 schema:name pubmed_id
107 schema:value 18216855
108 rdf:type schema:PropertyValue
109 Naa8fd31a90d444f3b31e3965253a0c4d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Gene Deletion
111 rdf:type schema:DefinedTerm
112 Nad6db42a6a26465282efa9f6a1890e75 rdf:first sg:person.0722261057.50
113 rdf:rest N6902e16ae9894298a94888d12aca7706
114 Nae42e4ff2c33454897da3522175a738d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Proteins
116 rdf:type schema:DefinedTerm
117 Nbab3b9362f4440fab0b040f8b51be374 schema:volumeNumber 451
118 rdf:type schema:PublicationVolume
119 Nbf44b63b9a484de389df6f47f8ce3821 rdf:first sg:person.01172146666.60
120 rdf:rest rdf:nil
121 Nd057d92afd4e414c961ef4e19e826825 rdf:first sg:person.0576727350.81
122 rdf:rest Nad6db42a6a26465282efa9f6a1890e75
123 Ndb390d42cbaf4f129d87ea5a6c5141ac schema:name dimensions_id
124 schema:value pub.1047861993
125 rdf:type schema:PropertyValue
126 Ndb96a730717d4530ac60b4b04f956302 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Mice
128 rdf:type schema:DefinedTerm
129 Ne08fd193188a4f07a12223f5dbe60a2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Cell Adhesion Molecules
131 rdf:type schema:DefinedTerm
132 Ne9411a1cac044fdcb52daf5e055991e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Retina
134 rdf:type schema:DefinedTerm
135 Nec5ae2c1532a4419b154f9e58185bacc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Animals
137 rdf:type schema:DefinedTerm
138 Nfc06e9a92cbf4c62abe9756eb1816b0a schema:issueNumber 7177
139 rdf:type schema:PublicationIssue
140 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
141 schema:name Medical and Health Sciences
142 rdf:type schema:DefinedTerm
143 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
144 schema:name Neurosciences
145 rdf:type schema:DefinedTerm
146 sg:grant.2378031 http://pending.schema.org/fundedItem sg:pub.10.1038/nature06514
147 rdf:type schema:MonetaryGrant
148 sg:grant.2574013 http://pending.schema.org/fundedItem sg:pub.10.1038/nature06514
149 rdf:type schema:MonetaryGrant
150 sg:journal.1018957 schema:issn 0028-0836
151 1476-4687
152 schema:name Nature
153 schema:publisher Springer Nature
154 rdf:type schema:Periodical
155 sg:person.01036507457.01 schema:affiliation grid-institutes:grid.32224.35
156 schema:familyName Masland
157 schema:givenName Richard H.
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036507457.01
159 rdf:type schema:Person
160 sg:person.01172146666.60 schema:affiliation grid-institutes:grid.249880.f
161 schema:familyName Burgess
162 schema:givenName Robert W.
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172146666.60
164 rdf:type schema:Person
165 sg:person.0576727350.81 schema:affiliation grid-institutes:grid.249880.f
166 schema:familyName Fuerst
167 schema:givenName Peter G.
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0576727350.81
169 rdf:type schema:Person
170 sg:person.0722261057.50 schema:affiliation grid-institutes:grid.467811.d
171 schema:familyName Koizumi
172 schema:givenName Amane
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722261057.50
174 rdf:type schema:Person
175 sg:pub.10.1038/nature05855 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040854933
176 https://doi.org/10.1038/nature05855
177 rdf:type schema:CreativeWork
178 sg:pub.10.1038/nature06099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053541205
179 https://doi.org/10.1038/nature06099
180 rdf:type schema:CreativeWork
181 sg:pub.10.1038/nature06147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032360637
182 https://doi.org/10.1038/nature06147
183 rdf:type schema:CreativeWork
184 sg:pub.10.1038/nature06469 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049991249
185 https://doi.org/10.1038/nature06469
186 rdf:type schema:CreativeWork
187 sg:pub.10.1038/ng1299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047549634
188 https://doi.org/10.1038/ng1299
189 rdf:type schema:CreativeWork
190 grid-institutes:grid.249880.f schema:alternateName The Jackson Laboratory, Bar Harbor, Maine 04609, USA
191 schema:name The Jackson Laboratory, Bar Harbor, Maine 04609, USA
192 rdf:type schema:Organization
193 grid-institutes:grid.32224.35 schema:alternateName Massachusetts General Hospital, Boston, Massachusetts 02114, USA
194 schema:name Massachusetts General Hospital, Boston, Massachusetts 02114, USA
195 rdf:type schema:Organization
196 grid-institutes:grid.467811.d schema:alternateName Present address: National Institute for Physiological Sciences, 38 Nishigonaka, Myodaiji, Okazaki, 444-8585, Japan.
197 schema:name Massachusetts General Hospital, Boston, Massachusetts 02114, USA
198 Present address: National Institute for Physiological Sciences, 38 Nishigonaka, Myodaiji, Okazaki, 444-8585, Japan.
199 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...