Nuclear reprogramming and pluripotency View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-06

AUTHORS

Konrad Hochedlinger, Rudolf Jaenisch

ABSTRACT

The cloning of mammals from differentiated donor cells has refuted the old dogma that development is an irreversible process. It has demonstrated that the oocyte can reprogramme an adult nucleus into an embryonic state that can direct development of a new organism. The prospect of deriving patient-specific embryonic stem cells by nuclear transfer underscores the potential use of this technology in regenerative medicine. The future challenge will be to study alternatives to nuclear transfer in order to recapitulate reprogramming in a Petri dish without the use of oocytes. More... »

PAGES

1061-1067

References to SciGraph publications

  • 2006-04. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells in NATURE GENETICS
  • 2002-02. Monoclonal mice generated by nuclear transfer from mature B and T donor cells in NATURE
  • 2003-08. Embryonic stem cells generated by nuclear transfer of human somatic nuclei into rabbit oocytes in CELL RESEARCH
  • 1981-07. Establishment in culture of pluripotential cells from mouse embryos in NATURE
  • 1998-07. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei in NATURE
  • 2000-04. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells in NATURE GENETICS
  • 2002-03. Early death of mice cloned from somatic cells in NATURE GENETICS
  • 2004-03-25. Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons in NATURE
  • 1992-10. Long-term proliferation of mouse primordial germ cells in culture in NATURE
  • 1998-03. Epigenotype switching of imprintable loci in embryonic germ cells in DEVELOPMENT GENES AND EVOLUTION
  • 2002-07. Pluripotency of mesenchymal stem cells derived from adult marrow in NATURE
  • 2002-05. Reprogramming fibroblasts to express T-cell functions using cell extracts in NATURE BIOTECHNOLOGY
  • 2006-01. Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres in NATURE
  • 1997-02. Viable offspring derived from fetal and adult mammalian cells in NATURE
  • 1999-10. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5 in NATURE
  • 2000-02. Generation of mice from wild-type and targeted ES cells by nuclear cloning in NATURE GENETICS
  • 2004-10. DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei in NATURE CELL BIOLOGY
  • 2004-09. Self-renewal of teratocarcinoma and embryonic stem cells in ONCOGENE
  • 2006-04. Pluripotency of spermatogonial stem cells from adult mouse testis in NATURE
  • 2006-05. Polycomb complexes repress developmental regulators in murine embryonic stem cells in NATURE
  • 2002-03. Cloned mice have an obese phenotype not transmitted to their offspring in NATURE MEDICINE
  • 2004-03. Mice cloned from olfactory sensory neurons in NATURE
  • 1999-06. Cloning of male mice from adult tail-tip cells in NATURE GENETICS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature04955

    DOI

    http://dx.doi.org/10.1038/nature04955

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1014595021

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/16810240


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