A possible unifying principle for mechanosensation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-08

AUTHORS

Ching Kung

ABSTRACT

Of Aristotle's five senses, we know that sight, smell and much of taste are initiated by ligands binding to G-protein-coupled receptors; however, the mechanical sensations of touch and hearing remain without a clear understanding of their molecular basis. Recently, the relevant force-transducing molecules--the mechanosensitive ion channels--have been identified. Such channel proteins purified from bacteria sense forces from the lipid bilayer in the absence of other proteins. Recent evidence has shown that lipids are also intimately involved in opening and closing the mechanosensitive channels of fungal, plant and animal species. More... »

PAGES

647

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature03896

DOI

http://dx.doi.org/10.1038/nature03896

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040837309

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16079835


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