Targeted cancer therapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-11

AUTHORS

Charles Sawyers

ABSTRACT

Disruption of the normal regulation of cell-cycle progression and division lies at the heart of the events leading to cancer. Complex networks of regulatory factors, the tumour microenvironment and stress signals, such as those resulting from damaged DNA, dictate whether cancer cells proliferate or die. Recent progress in understanding the molecular changes that underlie cancer development offer the prospect of specifically targeting malfunctioning molecules and pathways to achieve more effective and rational cancer therapy. More... »

PAGES

294-297

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature03095

DOI

http://dx.doi.org/10.1038/nature03095

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010000533

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15549090


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