The International HapMap Project View Full Text


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Article Info

DATE

2003-12

AUTHORS

Richard A. Gibbs, John W. Belmont, Paul Hardenbol, Thomas D. Willis, Fuli Yu, Houcan Zhang, Changqing Zeng, Ichiro Matsuda, Yoshimitsu Fukushima, Darryl R. Macer, Eiko Suda, Lincoln D. Stein, Fiona Cunningham, Ardavan Kanani, Gudmundur A. Thorisson, Aravinda Chakravarti, Peter E. Chen, David J. Cutler, Carl S. Kashuk, Peter Donnelly, Jonathan Marchini, Gilean A. T. McVean, Simon R. Myers, Lon R. Cardon, Gonçalo R. Abecasis, Andrew Morris, Bruce S. Weir, James C. Mullikin, Stephen T. Sherry, Michael Feolo, David Altshuler, Mark J. Daly, Stephen F. Schaffner, Renzong Qiu, Alastair Kent, Georgia M. Dunston, Kazuto Kato, Norio Niikawa, Bartha M. Knoppers, Morris W. Foster, Ellen Wright Clayton, Vivian Ota Wang, Jessica Watkin, Erica Sodergren, George M. Weinstock, Richard K. Wilson, Lucinda L. Fulton, Jane Rogers, Bruce W. Birren, Hua Han, Hongguang Wang, Martin Godbout, John C. Wallenburg, Paul L'Archevêque, Guy Bellemare, Kazuo Todani, Takashi Fujita, Satoshi Tanaka, Arthur L. Holden, Eric H. Lai, Francis S. Collins, Lisa D. Brooks, Jean E. McEwen, Mark S. Guyer, Elke Jordan, Jane L. Peterson, Jack Spiegel, Lawrence M. Sung, Lynn F. Zacharia, Karen Kennedy, Michael G. Dunn, Richard Seabrook, Mark Shillito, Barbara Skene, John G. Stewart, David L. Valle, Lynn B. Jorde, Mildred K. Cho, Troy Duster, Marla Jasperse, Pui-Yan Kwok, Julio Licinio, Jeffrey C. Long, Patricia A. Marshall, Pilar N. Ossorio, Charles N. Rotimi, Charmaine D. M. Royal, Patricia Spallone, Sharon F. Terry, Eric S. Lander, Deborah A. Nickerson, David R. Bentley, Michael Boehnke, Panos Deloukas, Julie A. Douglas, Stacey B. Gabriel, Richard R. Hudson, Thomas J. Hudson, Leonid Kruglyak, Yusuke Nakamura, Robert L. Nussbaum, Toshihiro Tanaka

ABSTRACT

The goal of the International HapMap Project is to determine the common patterns of DNA sequence variation in the human genome and to make this information freely available in the public domain. An international consortium is developing a map of these patterns across the genome by determining the genotypes of one million or more sequence variants, their frequencies and the degree of association between them, in DNA samples from populations with ancestry from parts of Africa, Asia and Europe. The HapMap will allow the discovery of sequence variants that affect common disease, will facilitate development of diagnostic tools, and will enhance our ability to choose targets for therapeutic intervention. More... »

PAGES

789

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  • Journal

    TITLE

    Nature

    ISSUE

    6968

    VOLUME

    426

    Related Patents

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature02168

    DOI

    http://dx.doi.org/10.1038/nature02168

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1033654326

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14685227


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