Fitness costs of R-gene-mediated resistance in Arabidopsis thaliana View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-05

AUTHORS

D. Tian, M. B. Traw, J. Q. Chen, M. Kreitman, J. Bergelson

ABSTRACT

Resistance genes (R-genes) act as an immune system in plants by recognizing pathogens and inducing defensive pathways. Many R-gene loci are present in plant genomes, presumably reflecting the need to maintain a large repertoire of resistance alleles. These loci also often segregate for resistance and susceptibility alleles that natural selection has maintained as polymorphisms within a species for millions of years. Given the obvious advantage to an individual of being disease resistant, what prevents these resistance alleles from being driven to fixation by natural selection? A cost of resistance is one potential explanation; most models require a lower fitness of resistant individuals in the absence of pathogens for long-term persistence of susceptibility alleles. Here we test for the presence of a cost of resistance at the RPM1 locus of Arabidopsis thaliana. Results of a field experiment comparing the fitness of isogenic strains that differ in the presence or absence of RPM1 and its natural promoter reveal a large cost of RPM1, providing the first evidence that costs contribute to the maintenance of an ancient R-gene polymorphism. More... »

PAGES

74

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature01588

DOI

http://dx.doi.org/10.1038/nature01588

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1025476543

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12721627


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