From words to literature in structural proteomics View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-03

AUTHORS

Andrej Sali, Robert Glaeser, Thomas Earnest, Wolfgang Baumeister

ABSTRACT

Technical advances on several frontiers have expanded the applicability of existing methods in structural biology and helped close the resolution gaps between them. As a result, we are now poised to integrate structural information gathered at multiple levels of the biological hierarchy — from atoms to cells — into a common framework. The goal is a comprehensive description of the multitude of interactions between molecular entities, which in turn is a prerequisite for the discovery of general structural principles that underlie all cellular processes. More... »

PAGES

216-225

References to SciGraph publications

  • 1999-11. Protein interaction maps for complete genomes based on gene fusion events in NATURE
  • 2002-01. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry in NATURE
  • 1997-03. Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopy in NATURE
  • 2001-11-05. Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae in NATURE GENETICS
  • 1998-01. Structure of the αβ tubulin dimer by electron crystallography in NATURE
  • 2000-11. A new era in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 1999-11. Identification of in vivo substrates of the chaperonin GroEL in NATURE
  • 1999-10. Structural genomics: beyond the Human Genome Project in NATURE GENETICS
  • 2000-10. Structural determinants of water permeation through aquaporin-1 in NATURE
  • 2000-06. Genomics, gene expression and DNA arrays in NATURE
  • 1998-09. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex in NATURE GENETICS
  • 2002-03. Nmr in drug discovery in NATURE REVIEWS DRUG DISCOVERY
  • 1997-03. Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy in NATURE
  • 2002-06. The society of proteins in NATURE
  • 2001-06. Completeness in structural genomics in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 1999-11. A combined algorithm for genome-wide prediction of protein function in NATURE
  • 2002-01. Protein complexes take the bait in NATURE
  • 2000-11. Automation of X-ray crystallography in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2000-02. A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae in NATURE
  • 2002-01. Functional organization of the yeast proteome by systematic analysis of protein complexes in NATURE
  • 2002-07. NMR analysis of a 900K GroEL–GroES complex in NATURE
  • 1994-02. Atomic model of plant light-harvesting complex by electron crystallography in NATURE
  • 1996-03. Molecular docking programs successfully predict the binding of a β-lactamase inhibitory protein to TEM-1 β-lactamase in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2000-09. Structure of the 30S ribosomal subunit in NATURE
  • 2002-05-08. Comparative assessment of large-scale data sets of protein–protein interactions in NATURE
  • Journal

    TITLE

    Nature

    ISSUE

    6928

    VOLUME

    422

    Related Patents

  • Optical Testing Device
  • Membrane Probing System
  • Membrane Probing System
  • Membrane Probing Method Using Improved Contact
  • Wafer Probe Station Having A Skirting Component
  • Probe Station With Low Noise Characteristics
  • Probe Station With Low Noise Characteristics
  • Wafer Probe
  • Shielded Probe For Testing A Device Under Test
  • Probe Station Thermal Chuck With Shielding For Capacitive Current
  • Differential Waveguide Probe
  • Probe For Testing A Device Under Test
  • Probe Station
  • Probe Testing Structure
  • Probe Station With Low Inductance Path
  • Probe Head Having A Membrane Suspended Probe
  • Switched Suspended Conductor And Connection
  • Wafer Probe Station Having Environment Control Enclosure
  • System For Testing Semiconductors
  • Shielded Probe For Testing A Device Under Test
  • Wafer Probe Station Having Environment Control Enclosure
  • Membrane Probing Method Using Improved Contact
  • Method Of Replacing An Existing Contact Of A Wafer Probing Assembly
  • Chuck For Holding A Device Under Test
  • Membrane Probing System
  • Shielded Probe For Testing A Device Under Test
  • Chuck For Holding A Device Under Test
  • Probe Station Having Multiple Enclosures
  • Wideband Active-Passive Differential Signal Probe
  • Thermal Optical Chuck
  • Chuck For Holding A Device Under Test
  • Differential Signal Probe With Integral Balun
  • Chuck With Integrated Wafer Support
  • Probe Station With Two Platens
  • Thermal Optical Chuck
  • Test Structure And Probe For Differential Signals
  • Guarded Tub Enclosure
  • Replaceable Coupon For A Probing Apparatus
  • System For Testing Semiconductors
  • Interface For Testing Semiconductors
  • Wafer Probe Station Having A Skirting Component
  • Chuck With Integrated Wafer Support
  • Shielded Probe For High-Frequency Testing Of A Device Under Test
  • System For Evaluating Probing Networks
  • Localizing A Temperature Of A Device For Testing
  • Method Of Constructing A Membrane Probe
  • Membrane Probing Structure With Laterally Scrubbing Contacts
  • Probe For Combined Signals
  • Interface For Testing Semiconductors
  • Guarded Tub Enclosure
  • Membrane Probing System
  • On-Wafer Test Structures For Differential Signals
  • Probe Head Having A Membrane Suspended Probe
  • System For Evaluating Probing Networks
  • Shielded Probe For Testing A Device Under Test
  • Probe Station Thermal Chuck With Shielding For Capacitive Current
  • Probe Station With Low Noise Characteristics
  • Wafer Probe Station Having A Skirting Component
  • Shielded Probe For Testing A Device Under Test
  • Membrane Probing System With Local Contact Scrub
  • Differential Signal Probing System
  • Chuck For Holding A Device Under Test
  • Chuck With Integrated Wafer Support
  • Shielded Probe With Low Contact Resistance For Testing A Device Under Test
  • Probe For High Frequency Signals
  • Probe Station Having Multiple Enclosures
  • Double Sided Probing Structures
  • Chuck For Holding A Device Under Test
  • Probe For Combined Signals
  • Probe Holder For Testing Of A Test Device
  • Test Apparatus For Measuring A Characteristic Of A Device Under Test
  • Probing Apparatus With Impedance Optimized Interface
  • Probe Station With Low Inductance Path
  • Probe Station Thermal Chuck With Shielding For Capacitive Current
  • Chuck For Holding A Device Under Test
  • Method Of Electrically Contacting A Bond Pad Of A Device Under Test With A Probe
  • Probe Testing Structure
  • Calibration Structures For Differential Signal Probing
  • Wafer Probe
  • Switched Suspended Conductor And Connection
  • Active Wafer Probe
  • Test Structure And Probe For Differential Signals
  • Chuck For Holding A Device Under Test
  • Wafer Probe
  • Chuck For Holding A Device Under Test
  • Method Of Assembling A Wafer Probe
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nature01513

    DOI

    http://dx.doi.org/10.1038/nature01513

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1034051355

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12634795


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Crystallization", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Microscopy, Electron", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Models, Molecular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Protein Conformation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Proteome", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Proteomics", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Departments of Biopharmaceutical Sciences and Pharmaceutical Chemistry, and California Institute for Quantitative Biomedical Research, University of California, 94143, San Francisco, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.266102.1", 
              "name": [
                "Departments of Biopharmaceutical Sciences and Pharmaceutical Chemistry, and California Institute for Quantitative Biomedical Research, University of California, 94143, San Francisco, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sali", 
            "givenName": "Andrej", 
            "id": "sg:person.016432245657.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016432245657.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Molecular and Cell Biology, Stanley/Donner ASU, University of California, 94720, Berkeley, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.47840.3f", 
              "name": [
                "Department of Molecular and Cell Biology, Stanley/Donner ASU, University of California, 94720, Berkeley, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Glaeser", 
            "givenName": "Robert", 
            "id": "sg:person.0736635236.73", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736635236.73"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Physical Biosciences Division, Berkeley Center for Structural Biology, Lawrence Berkeley National Laboratory, 94720, Berkeley, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.184769.5", 
              "name": [
                "Physical Biosciences Division, Berkeley Center for Structural Biology, Lawrence Berkeley National Laboratory, 94720, Berkeley, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Earnest", 
            "givenName": "Thomas", 
            "id": "sg:person.01242017026.44", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242017026.44"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Structural Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18 a, 82152, Martinsried, Germany", 
              "id": "http://www.grid.ac/institutes/grid.418615.f", 
              "name": [
                "Department of Structural Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18 a, 82152, Martinsried, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Baumeister", 
            "givenName": "Wolfgang", 
            "id": "sg:person.0741421124.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741421124.07"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/415123a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013448487", 
              "https://doi.org/10.1038/415123a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsb0396-233", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049825643", 
              "https://doi.org/10.1038/nsb0396-233"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/415141a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001484556", 
              "https://doi.org/10.1038/415141a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature00860", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002305868", 
              "https://doi.org/10.1038/nature00860"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/34465", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016383987", 
              "https://doi.org/10.1038/34465"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35015701", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028135585", 
              "https://doi.org/10.1038/35015701"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/386091a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029610482", 
              "https://doi.org/10.1038/386091a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature750", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017837373", 
              "https://doi.org/10.1038/nature750"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/415180a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005267371", 
              "https://doi.org/10.1038/415180a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/47056", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029720868", 
              "https://doi.org/10.1038/47056"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35001009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035773549", 
              "https://doi.org/10.1038/35001009"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/13783", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037826339", 
              "https://doi.org/10.1038/13783"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrd748", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013463430", 
              "https://doi.org/10.1038/nrd748"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng776", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024019002", 
              "https://doi.org/10.1038/ng776"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/80689", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050941882", 
              "https://doi.org/10.1038/80689"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/88640", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046431857", 
              "https://doi.org/10.1038/88640"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/386088a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050523440", 
              "https://doi.org/10.1038/386088a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/45977", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002860173", 
              "https://doi.org/10.1038/45977"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/1700", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050797047", 
              "https://doi.org/10.1038/1700"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/367614a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046683584", 
              "https://doi.org/10.1038/367614a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35030006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013504492", 
              "https://doi.org/10.1038/35030006"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35036519", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047573149", 
              "https://doi.org/10.1038/35036519"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/417894a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024552089", 
              "https://doi.org/10.1038/417894a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/80754", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015626079", 
              "https://doi.org/10.1038/80754"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/47048", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029164285", 
              "https://doi.org/10.1038/47048"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2003-03", 
        "datePublishedReg": "2003-03-01", 
        "description": "Technical advances on several frontiers have expanded the applicability of existing methods in structural biology and helped close the resolution gaps between them. As a result, we are now poised to integrate structural information gathered at multiple levels of the biological hierarchy \u2014 from atoms to cells \u2014 into a common framework. The goal is a comprehensive description of the multitude of interactions between molecular entities, which in turn is a prerequisite for the discovery of general structural principles that underlie all cellular processes.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/nature01513", 
        "inLanguage": "en", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1018957", 
            "issn": [
              "0028-0836", 
              "1476-4687"
            ], 
            "name": "Nature", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "6928", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "422"
          }
        ], 
        "keywords": [
          "cellular processes", 
          "structural proteomics", 
          "structural biology", 
          "biological hierarchy", 
          "multitude of interactions", 
          "resolution gap", 
          "structural information", 
          "structural principles", 
          "general structural principles", 
          "molecular entities", 
          "proteomics", 
          "biology", 
          "multiple levels", 
          "technical advances", 
          "comprehensive description", 
          "cells", 
          "discovery", 
          "multitude", 
          "interaction", 
          "prerequisite", 
          "advances", 
          "levels", 
          "turn", 
          "process", 
          "results", 
          "frontier", 
          "information", 
          "description", 
          "hierarchy", 
          "common framework", 
          "gap", 
          "goal", 
          "entities", 
          "method", 
          "principles", 
          "applicability", 
          "framework", 
          "atoms", 
          "words"
        ], 
        "name": "From words to literature in structural proteomics", 
        "pagination": "216-225", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1034051355"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nature01513"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "12634795"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nature01513", 
          "https://app.dimensions.ai/details/publication/pub.1034051355"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2021-12-01T19:15", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_373.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/nature01513"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature01513'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature01513'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature01513'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature01513'


     

    This table displays all metadata directly associated to this object as RDF triples.

    263 TRIPLES      22 PREDICATES      99 URIs      66 LITERALS      15 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nature01513 schema:about N3269902120bf497cbee9e934ce82c9ea
    2 N7121e54aeaa640f3b0d145812334b94f
    3 Nb1cb94dfb9644b93b3feb354d606f7a9
    4 Nc1f526b3f997433ab12be2d1609fdaf6
    5 Ncf720cc72d174c448704824a703c2253
    6 Ndac35bc32c684bed87a8a16dcbc1c369
    7 Ne1f06b976e204135abc538ca366bc76b
    8 Nfed4bd53a35c441e9631fb3c57b841a2
    9 anzsrc-for:06
    10 anzsrc-for:0601
    11 schema:author Neeafaa782c6a4aed9a0168a9bfc106e9
    12 schema:citation sg:pub.10.1038/13783
    13 sg:pub.10.1038/1700
    14 sg:pub.10.1038/34465
    15 sg:pub.10.1038/35001009
    16 sg:pub.10.1038/35015701
    17 sg:pub.10.1038/35030006
    18 sg:pub.10.1038/35036519
    19 sg:pub.10.1038/367614a0
    20 sg:pub.10.1038/386088a0
    21 sg:pub.10.1038/386091a0
    22 sg:pub.10.1038/415123a
    23 sg:pub.10.1038/415141a
    24 sg:pub.10.1038/415180a
    25 sg:pub.10.1038/417894a
    26 sg:pub.10.1038/45977
    27 sg:pub.10.1038/47048
    28 sg:pub.10.1038/47056
    29 sg:pub.10.1038/80689
    30 sg:pub.10.1038/80754
    31 sg:pub.10.1038/88640
    32 sg:pub.10.1038/nature00860
    33 sg:pub.10.1038/nature750
    34 sg:pub.10.1038/ng776
    35 sg:pub.10.1038/nrd748
    36 sg:pub.10.1038/nsb0396-233
    37 schema:datePublished 2003-03
    38 schema:datePublishedReg 2003-03-01
    39 schema:description Technical advances on several frontiers have expanded the applicability of existing methods in structural biology and helped close the resolution gaps between them. As a result, we are now poised to integrate structural information gathered at multiple levels of the biological hierarchy — from atoms to cells — into a common framework. The goal is a comprehensive description of the multitude of interactions between molecular entities, which in turn is a prerequisite for the discovery of general structural principles that underlie all cellular processes.
    40 schema:genre article
    41 schema:inLanguage en
    42 schema:isAccessibleForFree false
    43 schema:isPartOf N56e31d9db228492ba93a4e47ca235a15
    44 N9260ccd8c7f448d792fad3597c755ed5
    45 sg:journal.1018957
    46 schema:keywords advances
    47 applicability
    48 atoms
    49 biological hierarchy
    50 biology
    51 cells
    52 cellular processes
    53 common framework
    54 comprehensive description
    55 description
    56 discovery
    57 entities
    58 framework
    59 frontier
    60 gap
    61 general structural principles
    62 goal
    63 hierarchy
    64 information
    65 interaction
    66 levels
    67 method
    68 molecular entities
    69 multiple levels
    70 multitude
    71 multitude of interactions
    72 prerequisite
    73 principles
    74 process
    75 proteomics
    76 resolution gap
    77 results
    78 structural biology
    79 structural information
    80 structural principles
    81 structural proteomics
    82 technical advances
    83 turn
    84 words
    85 schema:name From words to literature in structural proteomics
    86 schema:pagination 216-225
    87 schema:productId N10774ec5c77842e4a8a76cdaa1ff1786
    88 N23442b4c081e41e1b8c6e566981ed947
    89 Naf1ba034c37a47deba65d34ffd74d03c
    90 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034051355
    91 https://doi.org/10.1038/nature01513
    92 schema:sdDatePublished 2021-12-01T19:15
    93 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    94 schema:sdPublisher N604ee7acaeab4ebaa708da893c428c2d
    95 schema:url https://doi.org/10.1038/nature01513
    96 sgo:license sg:explorer/license/
    97 sgo:sdDataset articles
    98 rdf:type schema:ScholarlyArticle
    99 N10774ec5c77842e4a8a76cdaa1ff1786 schema:name dimensions_id
    100 schema:value pub.1034051355
    101 rdf:type schema:PropertyValue
    102 N23442b4c081e41e1b8c6e566981ed947 schema:name doi
    103 schema:value 10.1038/nature01513
    104 rdf:type schema:PropertyValue
    105 N275c024ea3ba436ea11e61f3c414acad rdf:first sg:person.0741421124.07
    106 rdf:rest rdf:nil
    107 N3269902120bf497cbee9e934ce82c9ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    108 schema:name Models, Molecular
    109 rdf:type schema:DefinedTerm
    110 N3b02897820cb4d40b29b84222ae54c2c rdf:first sg:person.0736635236.73
    111 rdf:rest Ne70eb787a95648a7bb58dddbe49214e3
    112 N56e31d9db228492ba93a4e47ca235a15 schema:issueNumber 6928
    113 rdf:type schema:PublicationIssue
    114 N604ee7acaeab4ebaa708da893c428c2d schema:name Springer Nature - SN SciGraph project
    115 rdf:type schema:Organization
    116 N7121e54aeaa640f3b0d145812334b94f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    117 schema:name Crystallization
    118 rdf:type schema:DefinedTerm
    119 N9260ccd8c7f448d792fad3597c755ed5 schema:volumeNumber 422
    120 rdf:type schema:PublicationVolume
    121 Naf1ba034c37a47deba65d34ffd74d03c schema:name pubmed_id
    122 schema:value 12634795
    123 rdf:type schema:PropertyValue
    124 Nb1cb94dfb9644b93b3feb354d606f7a9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    125 schema:name Humans
    126 rdf:type schema:DefinedTerm
    127 Nc1f526b3f997433ab12be2d1609fdaf6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    128 schema:name Microscopy, Electron
    129 rdf:type schema:DefinedTerm
    130 Ncf720cc72d174c448704824a703c2253 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    131 schema:name Proteomics
    132 rdf:type schema:DefinedTerm
    133 Ndac35bc32c684bed87a8a16dcbc1c369 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    134 schema:name Protein Conformation
    135 rdf:type schema:DefinedTerm
    136 Ne1f06b976e204135abc538ca366bc76b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    137 schema:name Animals
    138 rdf:type schema:DefinedTerm
    139 Ne70eb787a95648a7bb58dddbe49214e3 rdf:first sg:person.01242017026.44
    140 rdf:rest N275c024ea3ba436ea11e61f3c414acad
    141 Neeafaa782c6a4aed9a0168a9bfc106e9 rdf:first sg:person.016432245657.81
    142 rdf:rest N3b02897820cb4d40b29b84222ae54c2c
    143 Nfed4bd53a35c441e9631fb3c57b841a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    144 schema:name Proteome
    145 rdf:type schema:DefinedTerm
    146 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    147 schema:name Biological Sciences
    148 rdf:type schema:DefinedTerm
    149 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    150 schema:name Biochemistry and Cell Biology
    151 rdf:type schema:DefinedTerm
    152 sg:journal.1018957 schema:issn 0028-0836
    153 1476-4687
    154 schema:name Nature
    155 schema:publisher Springer Nature
    156 rdf:type schema:Periodical
    157 sg:person.01242017026.44 schema:affiliation grid-institutes:grid.184769.5
    158 schema:familyName Earnest
    159 schema:givenName Thomas
    160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242017026.44
    161 rdf:type schema:Person
    162 sg:person.016432245657.81 schema:affiliation grid-institutes:grid.266102.1
    163 schema:familyName Sali
    164 schema:givenName Andrej
    165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016432245657.81
    166 rdf:type schema:Person
    167 sg:person.0736635236.73 schema:affiliation grid-institutes:grid.47840.3f
    168 schema:familyName Glaeser
    169 schema:givenName Robert
    170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736635236.73
    171 rdf:type schema:Person
    172 sg:person.0741421124.07 schema:affiliation grid-institutes:grid.418615.f
    173 schema:familyName Baumeister
    174 schema:givenName Wolfgang
    175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741421124.07
    176 rdf:type schema:Person
    177 sg:pub.10.1038/13783 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037826339
    178 https://doi.org/10.1038/13783
    179 rdf:type schema:CreativeWork
    180 sg:pub.10.1038/1700 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050797047
    181 https://doi.org/10.1038/1700
    182 rdf:type schema:CreativeWork
    183 sg:pub.10.1038/34465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016383987
    184 https://doi.org/10.1038/34465
    185 rdf:type schema:CreativeWork
    186 sg:pub.10.1038/35001009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035773549
    187 https://doi.org/10.1038/35001009
    188 rdf:type schema:CreativeWork
    189 sg:pub.10.1038/35015701 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028135585
    190 https://doi.org/10.1038/35015701
    191 rdf:type schema:CreativeWork
    192 sg:pub.10.1038/35030006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013504492
    193 https://doi.org/10.1038/35030006
    194 rdf:type schema:CreativeWork
    195 sg:pub.10.1038/35036519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047573149
    196 https://doi.org/10.1038/35036519
    197 rdf:type schema:CreativeWork
    198 sg:pub.10.1038/367614a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046683584
    199 https://doi.org/10.1038/367614a0
    200 rdf:type schema:CreativeWork
    201 sg:pub.10.1038/386088a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050523440
    202 https://doi.org/10.1038/386088a0
    203 rdf:type schema:CreativeWork
    204 sg:pub.10.1038/386091a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029610482
    205 https://doi.org/10.1038/386091a0
    206 rdf:type schema:CreativeWork
    207 sg:pub.10.1038/415123a schema:sameAs https://app.dimensions.ai/details/publication/pub.1013448487
    208 https://doi.org/10.1038/415123a
    209 rdf:type schema:CreativeWork
    210 sg:pub.10.1038/415141a schema:sameAs https://app.dimensions.ai/details/publication/pub.1001484556
    211 https://doi.org/10.1038/415141a
    212 rdf:type schema:CreativeWork
    213 sg:pub.10.1038/415180a schema:sameAs https://app.dimensions.ai/details/publication/pub.1005267371
    214 https://doi.org/10.1038/415180a
    215 rdf:type schema:CreativeWork
    216 sg:pub.10.1038/417894a schema:sameAs https://app.dimensions.ai/details/publication/pub.1024552089
    217 https://doi.org/10.1038/417894a
    218 rdf:type schema:CreativeWork
    219 sg:pub.10.1038/45977 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002860173
    220 https://doi.org/10.1038/45977
    221 rdf:type schema:CreativeWork
    222 sg:pub.10.1038/47048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029164285
    223 https://doi.org/10.1038/47048
    224 rdf:type schema:CreativeWork
    225 sg:pub.10.1038/47056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029720868
    226 https://doi.org/10.1038/47056
    227 rdf:type schema:CreativeWork
    228 sg:pub.10.1038/80689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050941882
    229 https://doi.org/10.1038/80689
    230 rdf:type schema:CreativeWork
    231 sg:pub.10.1038/80754 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015626079
    232 https://doi.org/10.1038/80754
    233 rdf:type schema:CreativeWork
    234 sg:pub.10.1038/88640 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046431857
    235 https://doi.org/10.1038/88640
    236 rdf:type schema:CreativeWork
    237 sg:pub.10.1038/nature00860 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002305868
    238 https://doi.org/10.1038/nature00860
    239 rdf:type schema:CreativeWork
    240 sg:pub.10.1038/nature750 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017837373
    241 https://doi.org/10.1038/nature750
    242 rdf:type schema:CreativeWork
    243 sg:pub.10.1038/ng776 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024019002
    244 https://doi.org/10.1038/ng776
    245 rdf:type schema:CreativeWork
    246 sg:pub.10.1038/nrd748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013463430
    247 https://doi.org/10.1038/nrd748
    248 rdf:type schema:CreativeWork
    249 sg:pub.10.1038/nsb0396-233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049825643
    250 https://doi.org/10.1038/nsb0396-233
    251 rdf:type schema:CreativeWork
    252 grid-institutes:grid.184769.5 schema:alternateName Physical Biosciences Division, Berkeley Center for Structural Biology, Lawrence Berkeley National Laboratory, 94720, Berkeley, California, USA
    253 schema:name Physical Biosciences Division, Berkeley Center for Structural Biology, Lawrence Berkeley National Laboratory, 94720, Berkeley, California, USA
    254 rdf:type schema:Organization
    255 grid-institutes:grid.266102.1 schema:alternateName Departments of Biopharmaceutical Sciences and Pharmaceutical Chemistry, and California Institute for Quantitative Biomedical Research, University of California, 94143, San Francisco, California, USA
    256 schema:name Departments of Biopharmaceutical Sciences and Pharmaceutical Chemistry, and California Institute for Quantitative Biomedical Research, University of California, 94143, San Francisco, California, USA
    257 rdf:type schema:Organization
    258 grid-institutes:grid.418615.f schema:alternateName Department of Structural Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18 a, 82152, Martinsried, Germany
    259 schema:name Department of Structural Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18 a, 82152, Martinsried, Germany
    260 rdf:type schema:Organization
    261 grid-institutes:grid.47840.3f schema:alternateName Department of Molecular and Cell Biology, Stanley/Donner ASU, University of California, 94720, Berkeley, California, USA
    262 schema:name Department of Molecular and Cell Biology, Stanley/Donner ASU, University of California, 94720, Berkeley, California, USA
    263 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...