Engineered gene circuits View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2002-11

AUTHORS

Jeff Hasty, David McMillen, J. J. Collins

ABSTRACT

A central focus of postgenomic research will be to understand how cellular phenomena arise from the connectivity of genes and proteins. This connectivity generates molecular network diagrams that resemble complex electrical circuits, and a systematic understanding will require the development of a mathematical framework for describing the circuitry. From an engineering perspective, the natural path towards such a framework is the construction and analysis of the underlying submodules that constitute the network. Recent experimental advances in both sequencing and genetic engineering have made this approach feasible through the design and implementation of synthetic gene networks amenable to mathematical modelling and quantitative analysis. These developments have signalled the emergence of a gene circuit discipline, which provides a framework for predicting and evaluating the dynamics of cellular processes. Synthetic gene networks will also lead to new logical forms of cellular control, which could have important applications in functional genomics, nanotechnology, and gene and cell therapy. More... »

PAGES

224-230

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature01257

DOI

http://dx.doi.org/10.1038/nature01257

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022279877

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12432407


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Applied Mathematics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/01", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Mathematical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Feedback, Physiological", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genomics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Biological", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Signal Transduction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Systems Theory", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of California, San Diego", 
          "id": "https://www.grid.ac/institutes/grid.266100.3", 
          "name": [
            "*Department of Bioengineering, University of California San Diego, La Jolla, California 92093, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hasty", 
        "givenName": "Jeff", 
        "id": "sg:person.010167164547.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010167164547.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Boston University", 
          "id": "https://www.grid.ac/institutes/grid.189504.1", 
          "name": [
            "\u2020Center for BioDynamics and Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McMillen", 
        "givenName": "David", 
        "id": "sg:person.01325754617.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325754617.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Boston University", 
          "id": "https://www.grid.ac/institutes/grid.189504.1", 
          "name": [
            "\u2020Center for BioDynamics and Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Collins", 
        "givenName": "J. J.", 
        "id": "sg:person.0633456602.93", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633456602.93"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0006-3495(99)77078-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000332755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(02)75635-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001586065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35002131", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002786107", 
          "https://doi.org/10.1038/35002131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35002131", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002786107", 
          "https://doi.org/10.1038/35002131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1521-1878(199910)21:10<833::aid-bies5>3.0.co;2-p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003481995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5193(75)80056-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004063621"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1067407", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004364700"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00198772", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007511494", 
          "https://doi.org/10.1007/bf00198772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00198772", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007511494", 
          "https://doi.org/10.1007/bf00198772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-7799(01)01691-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008495994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1091/mbc.11.1.369", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008850988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(80)90383-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012401734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35002258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012923840", 
          "https://doi.org/10.1038/35002258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35002258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012923840", 
          "https://doi.org/10.1038/35002258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jtbi.2000.2072", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015363883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.022642299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015995741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bbpc.19940980916", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016325879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35002125", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016534270", 
          "https://doi.org/10.1038/35002125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35002125", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016534270", 
          "https://doi.org/10.1038/35002125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.1345702", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016574145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.151588598", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017925340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.94.3.814", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019128746"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35011540", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019498862", 
          "https://doi.org/10.1038/35011540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35011540", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019498862", 
          "https://doi.org/10.1038/35011540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.040411297", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023613466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0933416100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023650314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35042675", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023763406", 
          "https://doi.org/10.1038/35042675"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35042675", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023763406", 
          "https://doi.org/10.1038/35042675"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.110057697", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023820925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.micro.50.1.727", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024331808"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00276388", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024369473", 
          "https://doi.org/10.1007/bf00276388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00276388", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024369473", 
          "https://doi.org/10.1007/bf00276388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0960-9822(00)00440-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024619096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.94.17.9147", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025449861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1521-1878(199910)21:10<866::aid-bies9>3.0.co;2-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026058080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35066056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028177673", 
          "https://doi.org/10.1038/35066056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35066056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028177673", 
          "https://doi.org/10.1038/35066056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng869", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030126259", 
          "https://doi.org/10.1038/ng869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng869", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030126259", 
          "https://doi.org/10.1038/ng869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jtbi.1995.0014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030625716"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt1101-1035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031703717", 
          "https://doi.org/10.1038/nbt1101-1035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt1101-1035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031703717", 
          "https://doi.org/10.1038/nbt1101-1035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35014651", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033127471", 
          "https://doi.org/10.1038/35014651"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35014651", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033127471", 
          "https://doi.org/10.1038/35014651"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1521-1878(200001)22:1<84::aid-bies13>3.0.co;2-i", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033526776"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5193(85)80228-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033975732"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0896-6273(00)81194-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034260179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/b978-0-12-543105-7.50008-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035497062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/20.10.2528", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035991528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/252546a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036485599", 
          "https://doi.org/10.1038/252546a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.97.10.5031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039367049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02460618", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041971380", 
          "https://doi.org/10.1007/bf02460618"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02460618", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041971380", 
          "https://doi.org/10.1007/bf02460618"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-5193(73)90208-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044522507"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5193(05)80111-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045404147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.092133899", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046440262"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5193(74)80037-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046489642"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)80566-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047627332"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1369-5274(99)00025-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047936616"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.97.14.7865", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048352683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(01)75949-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051098002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0955-0674(02)00314-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051167647"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/417329a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051701289", 
          "https://doi.org/10.1038/417329a"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/417329a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051701289", 
          "https://doi.org/10.1038/417329a"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/074873098128999934", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052637414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/074873098128999934", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052637414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.431518", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058009550"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/sqb.1961.026.01.048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060403442"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1103/physreve.65.051914", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060728449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1103/physreve.65.051914", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060728449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1103/physrevlett.88.148101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060824706"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1103/physrevlett.88.148101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060824706"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.7624793", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062648210"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083300818", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2002-11", 
    "datePublishedReg": "2002-11-01", 
    "description": "A central focus of postgenomic research will be to understand how cellular phenomena arise from the connectivity of genes and proteins. This connectivity generates molecular network diagrams that resemble complex electrical circuits, and a systematic understanding will require the development of a mathematical framework for describing the circuitry. From an engineering perspective, the natural path towards such a framework is the construction and analysis of the underlying submodules that constitute the network. Recent experimental advances in both sequencing and genetic engineering have made this approach feasible through the design and implementation of synthetic gene networks amenable to mathematical modelling and quantitative analysis. These developments have signalled the emergence of a gene circuit discipline, which provides a framework for predicting and evaluating the dynamics of cellular processes. Synthetic gene networks will also lead to new logical forms of cellular control, which could have important applications in functional genomics, nanotechnology, and gene and cell therapy.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nature01257", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6912", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "420"
      }
    ], 
    "name": "Engineered gene circuits", 
    "pagination": "224-230", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "6a255342452b9dcf92c67c67ab3622fe434c4711e47881b98b99324c7d09caa3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "12432407"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature01257"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1022279877"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature01257", 
      "https://app.dimensions.ai/details/publication/pub.1022279877"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:00", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000365_0000000365/records_71704_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/nature01257"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature01257'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature01257'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature01257'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature01257'


 

This table displays all metadata directly associated to this object as RDF triples.

313 TRIPLES      21 PREDICATES      97 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature01257 schema:about N3255a354ed48403f9af75f9be5a9b99d
2 N392fa3b3153543a9866bc56602b68ce4
3 N4500600ff12443a181c1adf3ecee5842
4 N73032651470d42baa3ad1932180b5724
5 N9d69ddd6edbd40a4a0f006a2a4e67e2b
6 Naf07f272718847ce9aa16273f7123017
7 Nbab0d19662c34eda875029c4b936bbe5
8 Ncd1bb69cc03b43e5ad3b3a5848189a9e
9 Ne9467cc9cd124477aa20df7897762e9e
10 Neb247ad2f4614ca1b93818b84b231eb2
11 anzsrc-for:01
12 anzsrc-for:0102
13 schema:author Ne7c1c433fb464ac4acedf8278a393af7
14 schema:citation sg:pub.10.1007/bf00198772
15 sg:pub.10.1007/bf00276388
16 sg:pub.10.1007/bf02460618
17 sg:pub.10.1038/252546a0
18 sg:pub.10.1038/35002125
19 sg:pub.10.1038/35002131
20 sg:pub.10.1038/35002258
21 sg:pub.10.1038/35011540
22 sg:pub.10.1038/35014651
23 sg:pub.10.1038/35042675
24 sg:pub.10.1038/35066056
25 sg:pub.10.1038/417329a
26 sg:pub.10.1038/nbt1101-1035
27 sg:pub.10.1038/ng869
28 https://app.dimensions.ai/details/publication/pub.1083300818
29 https://doi.org/10.1002/(sici)1521-1878(199910)21:10<833::aid-bies5>3.0.co;2-p
30 https://doi.org/10.1002/(sici)1521-1878(199910)21:10<866::aid-bies9>3.0.co;2-1
31 https://doi.org/10.1002/(sici)1521-1878(200001)22:1<84::aid-bies13>3.0.co;2-i
32 https://doi.org/10.1002/bbpc.19940980916
33 https://doi.org/10.1006/jtbi.1995.0014
34 https://doi.org/10.1006/jtbi.2000.2072
35 https://doi.org/10.1016/0022-5193(73)90208-7
36 https://doi.org/10.1016/0092-8674(80)90383-9
37 https://doi.org/10.1016/b978-0-12-543105-7.50008-7
38 https://doi.org/10.1016/s0006-3495(01)75949-8
39 https://doi.org/10.1016/s0006-3495(02)75635-x
40 https://doi.org/10.1016/s0006-3495(99)77078-5
41 https://doi.org/10.1016/s0022-5193(05)80111-0
42 https://doi.org/10.1016/s0022-5193(74)80037-8
43 https://doi.org/10.1016/s0022-5193(75)80056-7
44 https://doi.org/10.1016/s0022-5193(85)80228-9
45 https://doi.org/10.1016/s0092-8674(00)80566-8
46 https://doi.org/10.1016/s0167-7799(01)01691-2
47 https://doi.org/10.1016/s0896-6273(00)81194-0
48 https://doi.org/10.1016/s0955-0674(02)00314-9
49 https://doi.org/10.1016/s0960-9822(00)00440-1
50 https://doi.org/10.1016/s1369-5274(99)00025-9
51 https://doi.org/10.1063/1.1345702
52 https://doi.org/10.1063/1.431518
53 https://doi.org/10.1073/pnas.022642299
54 https://doi.org/10.1073/pnas.040411297
55 https://doi.org/10.1073/pnas.092133899
56 https://doi.org/10.1073/pnas.0933416100
57 https://doi.org/10.1073/pnas.110057697
58 https://doi.org/10.1073/pnas.151588598
59 https://doi.org/10.1073/pnas.94.17.9147
60 https://doi.org/10.1073/pnas.94.3.814
61 https://doi.org/10.1073/pnas.97.10.5031
62 https://doi.org/10.1073/pnas.97.14.7865
63 https://doi.org/10.1091/mbc.11.1.369
64 https://doi.org/10.1093/emboj/20.10.2528
65 https://doi.org/10.1101/sqb.1961.026.01.048
66 https://doi.org/10.1103/physreve.65.051914
67 https://doi.org/10.1103/physrevlett.88.148101
68 https://doi.org/10.1126/science.1067407
69 https://doi.org/10.1126/science.7624793
70 https://doi.org/10.1146/annurev.micro.50.1.727
71 https://doi.org/10.1177/074873098128999934
72 schema:datePublished 2002-11
73 schema:datePublishedReg 2002-11-01
74 schema:description A central focus of postgenomic research will be to understand how cellular phenomena arise from the connectivity of genes and proteins. This connectivity generates molecular network diagrams that resemble complex electrical circuits, and a systematic understanding will require the development of a mathematical framework for describing the circuitry. From an engineering perspective, the natural path towards such a framework is the construction and analysis of the underlying submodules that constitute the network. Recent experimental advances in both sequencing and genetic engineering have made this approach feasible through the design and implementation of synthetic gene networks amenable to mathematical modelling and quantitative analysis. These developments have signalled the emergence of a gene circuit discipline, which provides a framework for predicting and evaluating the dynamics of cellular processes. Synthetic gene networks will also lead to new logical forms of cellular control, which could have important applications in functional genomics, nanotechnology, and gene and cell therapy.
75 schema:genre research_article
76 schema:inLanguage en
77 schema:isAccessibleForFree true
78 schema:isPartOf N3a6b6c26255b44418f67819c99147728
79 Ncedf96d876714d9aa600699cd3f44ad0
80 sg:journal.1018957
81 schema:name Engineered gene circuits
82 schema:pagination 224-230
83 schema:productId N02de5146c6d34b329d9d663384b7bc98
84 N6ca03533ec9041b09e9946b6b850e3e6
85 N6ff527a807cf460ead2df683799d1b99
86 N95a9e71e12734959a723c646ba67eeef
87 Nb5952f9098ad44aab7564c383ff26834
88 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022279877
89 https://doi.org/10.1038/nature01257
90 schema:sdDatePublished 2019-04-11T13:00
91 schema:sdLicense https://scigraph.springernature.com/explorer/license/
92 schema:sdPublisher Ne87d734d8afd4bdc8d65c94bb2393cdd
93 schema:url http://www.nature.com/articles/nature01257
94 sgo:license sg:explorer/license/
95 sgo:sdDataset articles
96 rdf:type schema:ScholarlyArticle
97 N02de5146c6d34b329d9d663384b7bc98 schema:name dimensions_id
98 schema:value pub.1022279877
99 rdf:type schema:PropertyValue
100 N05c98473bad949ccb4cb014edb1b2a55 rdf:first sg:person.01325754617.16
101 rdf:rest N7af4054d4b0a4cb596cc06c822a802c7
102 N3255a354ed48403f9af75f9be5a9b99d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Gene Expression Regulation
104 rdf:type schema:DefinedTerm
105 N392fa3b3153543a9866bc56602b68ce4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Genetic Engineering
107 rdf:type schema:DefinedTerm
108 N3a6b6c26255b44418f67819c99147728 schema:issueNumber 6912
109 rdf:type schema:PublicationIssue
110 N4500600ff12443a181c1adf3ecee5842 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Models, Biological
112 rdf:type schema:DefinedTerm
113 N6ca03533ec9041b09e9946b6b850e3e6 schema:name readcube_id
114 schema:value 6a255342452b9dcf92c67c67ab3622fe434c4711e47881b98b99324c7d09caa3
115 rdf:type schema:PropertyValue
116 N6ff527a807cf460ead2df683799d1b99 schema:name doi
117 schema:value 10.1038/nature01257
118 rdf:type schema:PropertyValue
119 N73032651470d42baa3ad1932180b5724 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Animals
121 rdf:type schema:DefinedTerm
122 N7af4054d4b0a4cb596cc06c822a802c7 rdf:first sg:person.0633456602.93
123 rdf:rest rdf:nil
124 N95a9e71e12734959a723c646ba67eeef schema:name nlm_unique_id
125 schema:value 0410462
126 rdf:type schema:PropertyValue
127 N9d69ddd6edbd40a4a0f006a2a4e67e2b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Feedback, Physiological
129 rdf:type schema:DefinedTerm
130 Naf07f272718847ce9aa16273f7123017 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Genes
132 rdf:type schema:DefinedTerm
133 Nb5952f9098ad44aab7564c383ff26834 schema:name pubmed_id
134 schema:value 12432407
135 rdf:type schema:PropertyValue
136 Nbab0d19662c34eda875029c4b936bbe5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Cells
138 rdf:type schema:DefinedTerm
139 Ncd1bb69cc03b43e5ad3b3a5848189a9e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Genomics
141 rdf:type schema:DefinedTerm
142 Ncedf96d876714d9aa600699cd3f44ad0 schema:volumeNumber 420
143 rdf:type schema:PublicationVolume
144 Ne7c1c433fb464ac4acedf8278a393af7 rdf:first sg:person.010167164547.09
145 rdf:rest N05c98473bad949ccb4cb014edb1b2a55
146 Ne87d734d8afd4bdc8d65c94bb2393cdd schema:name Springer Nature - SN SciGraph project
147 rdf:type schema:Organization
148 Ne9467cc9cd124477aa20df7897762e9e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Systems Theory
150 rdf:type schema:DefinedTerm
151 Neb247ad2f4614ca1b93818b84b231eb2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Signal Transduction
153 rdf:type schema:DefinedTerm
154 anzsrc-for:01 schema:inDefinedTermSet anzsrc-for:
155 schema:name Mathematical Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:0102 schema:inDefinedTermSet anzsrc-for:
158 schema:name Applied Mathematics
159 rdf:type schema:DefinedTerm
160 sg:journal.1018957 schema:issn 0090-0028
161 1476-4687
162 schema:name Nature
163 rdf:type schema:Periodical
164 sg:person.010167164547.09 schema:affiliation https://www.grid.ac/institutes/grid.266100.3
165 schema:familyName Hasty
166 schema:givenName Jeff
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010167164547.09
168 rdf:type schema:Person
169 sg:person.01325754617.16 schema:affiliation https://www.grid.ac/institutes/grid.189504.1
170 schema:familyName McMillen
171 schema:givenName David
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325754617.16
173 rdf:type schema:Person
174 sg:person.0633456602.93 schema:affiliation https://www.grid.ac/institutes/grid.189504.1
175 schema:familyName Collins
176 schema:givenName J. J.
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633456602.93
178 rdf:type schema:Person
179 sg:pub.10.1007/bf00198772 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007511494
180 https://doi.org/10.1007/bf00198772
181 rdf:type schema:CreativeWork
182 sg:pub.10.1007/bf00276388 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024369473
183 https://doi.org/10.1007/bf00276388
184 rdf:type schema:CreativeWork
185 sg:pub.10.1007/bf02460618 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041971380
186 https://doi.org/10.1007/bf02460618
187 rdf:type schema:CreativeWork
188 sg:pub.10.1038/252546a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036485599
189 https://doi.org/10.1038/252546a0
190 rdf:type schema:CreativeWork
191 sg:pub.10.1038/35002125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016534270
192 https://doi.org/10.1038/35002125
193 rdf:type schema:CreativeWork
194 sg:pub.10.1038/35002131 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002786107
195 https://doi.org/10.1038/35002131
196 rdf:type schema:CreativeWork
197 sg:pub.10.1038/35002258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012923840
198 https://doi.org/10.1038/35002258
199 rdf:type schema:CreativeWork
200 sg:pub.10.1038/35011540 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019498862
201 https://doi.org/10.1038/35011540
202 rdf:type schema:CreativeWork
203 sg:pub.10.1038/35014651 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033127471
204 https://doi.org/10.1038/35014651
205 rdf:type schema:CreativeWork
206 sg:pub.10.1038/35042675 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023763406
207 https://doi.org/10.1038/35042675
208 rdf:type schema:CreativeWork
209 sg:pub.10.1038/35066056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028177673
210 https://doi.org/10.1038/35066056
211 rdf:type schema:CreativeWork
212 sg:pub.10.1038/417329a schema:sameAs https://app.dimensions.ai/details/publication/pub.1051701289
213 https://doi.org/10.1038/417329a
214 rdf:type schema:CreativeWork
215 sg:pub.10.1038/nbt1101-1035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031703717
216 https://doi.org/10.1038/nbt1101-1035
217 rdf:type schema:CreativeWork
218 sg:pub.10.1038/ng869 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030126259
219 https://doi.org/10.1038/ng869
220 rdf:type schema:CreativeWork
221 https://app.dimensions.ai/details/publication/pub.1083300818 schema:CreativeWork
222 https://doi.org/10.1002/(sici)1521-1878(199910)21:10<833::aid-bies5>3.0.co;2-p schema:sameAs https://app.dimensions.ai/details/publication/pub.1003481995
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1002/(sici)1521-1878(199910)21:10<866::aid-bies9>3.0.co;2-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026058080
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1002/(sici)1521-1878(200001)22:1<84::aid-bies13>3.0.co;2-i schema:sameAs https://app.dimensions.ai/details/publication/pub.1033526776
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1002/bbpc.19940980916 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016325879
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1006/jtbi.1995.0014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030625716
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1006/jtbi.2000.2072 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015363883
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1016/0022-5193(73)90208-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044522507
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/0092-8674(80)90383-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012401734
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/b978-0-12-543105-7.50008-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035497062
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/s0006-3495(01)75949-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051098002
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/s0006-3495(02)75635-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001586065
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/s0006-3495(99)77078-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000332755
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/s0022-5193(05)80111-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045404147
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1016/s0022-5193(74)80037-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046489642
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1016/s0022-5193(75)80056-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004063621
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1016/s0022-5193(85)80228-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033975732
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1016/s0092-8674(00)80566-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047627332
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1016/s0167-7799(01)01691-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008495994
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1016/s0896-6273(00)81194-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034260179
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1016/s0955-0674(02)00314-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051167647
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1016/s0960-9822(00)00440-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024619096
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1016/s1369-5274(99)00025-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047936616
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1063/1.1345702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016574145
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1063/1.431518 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058009550
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1073/pnas.022642299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015995741
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1073/pnas.040411297 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023613466
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1073/pnas.092133899 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046440262
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1073/pnas.0933416100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023650314
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1073/pnas.110057697 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023820925
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1073/pnas.151588598 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017925340
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1073/pnas.94.17.9147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025449861
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1073/pnas.94.3.814 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019128746
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1073/pnas.97.10.5031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039367049
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1073/pnas.97.14.7865 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048352683
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1091/mbc.11.1.369 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008850988
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1093/emboj/20.10.2528 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035991528
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1101/sqb.1961.026.01.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060403442
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1103/physreve.65.051914 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060728449
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1103/physrevlett.88.148101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060824706
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1126/science.1067407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004364700
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1126/science.7624793 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062648210
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1146/annurev.micro.50.1.727 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024331808
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1177/074873098128999934 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052637414
307 rdf:type schema:CreativeWork
308 https://www.grid.ac/institutes/grid.189504.1 schema:alternateName Boston University
309 schema:name †Center for BioDynamics and Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
310 rdf:type schema:Organization
311 https://www.grid.ac/institutes/grid.266100.3 schema:alternateName University of California, San Diego
312 schema:name *Department of Bioengineering, University of California San Diego, La Jolla, California 92093, USA
313 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...