Large clusters of co-expressed genes in the Drosophila genome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-12

AUTHORS

Alexander M. Boutanaev, Alla I. Kalmykova, Yuri Y. Shevelyov, Dmitry I. Nurminsky

ABSTRACT

Clustering of co-expressed, non-homologous genes on chromosomes implies their co-regulation. In lower eukaryotes, co-expressed genes are often found in pairs. Clustering of genes that share aspects of transcriptional regulation has also been reported in higher eukaryotes. To advance our understanding of the mode of coordinated gene regulation in multicellular organisms, we performed a genome-wide analysis of the chromosomal distribution of co-expressed genes in Drosophila. We identified a total of 1,661 testes-specific genes, one-third of which are clustered on chromosomes. The number of clusters of three or more genes is much higher than expected by chance. We observed a similar trend for genes upregulated in the embryo and in the adult head, although the expression pattern of individual genes cannot be predicted on the basis of chromosomal position alone. Our data suggest that the prevalent mechanism of transcriptional co-regulation in higher eukaryotes operates with extensive chromatin domains that comprise multiple genes. More... »

PAGES

666

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nature01216

DOI

http://dx.doi.org/10.1038/nature01216

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016219953

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12478293


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromatin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drosophila melanogaster", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Expressed Sequence Tags", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Profiling", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation, Developmental", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Insect", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Head", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multigene Family", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Organ Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Characteristics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stochastic Processes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Testis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "X Chromosome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Tufts University", 
          "id": "https://www.grid.ac/institutes/grid.429997.8", 
          "name": [
            "*Department of Anatomy & Cell Biology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boutanaev", 
        "givenName": "Alexander M.", 
        "id": "sg:person.0646110563.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646110563.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Russian Academy of Sciences", 
          "id": "https://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "\u2020Department of Molecular Genetics of Animals, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow 123182, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kalmykova", 
        "givenName": "Alla I.", 
        "id": "sg:person.01204366760.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204366760.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Russian Academy of Sciences", 
          "id": "https://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "\u2020Department of Molecular Genetics of Animals, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow 123182, Russia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shevelyov", 
        "givenName": "Yuri Y.", 
        "id": "sg:person.0764716762.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764716762.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tufts University", 
          "id": "https://www.grid.ac/institutes/grid.429997.8", 
          "name": [
            "*Department of Anatomy & Cell Biology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nurminsky", 
        "givenName": "Dmitry I.", 
        "id": "sg:person.01143017535.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143017535.95"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1475-4924-1-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001591994", 
          "https://doi.org/10.1186/1475-4924-1-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.2000.6254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007563541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1097-2765(00)80431-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008121454"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0962-8924(99)01693-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010391779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1098-2795(200006)56:2+<254::aid-mrd9>3.0.co;2-#", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010633740"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0968-0004(99)01516-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012810908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.13.18.2339", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014125903"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00251-001-0374-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018195584", 
          "https://doi.org/10.1007/s00251-001-0374-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/79896", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020624693", 
          "https://doi.org/10.1038/79896"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/79896", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020624693", 
          "https://doi.org/10.1038/79896"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.275.18.13827", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023925037"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1097-2765(00)80114-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027451892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.c100351200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034846799"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.c100765200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044686949"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.20.1.312-318.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044800469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature01012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046557993", 
          "https://doi.org/10.1038/nature01012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature01012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046557993", 
          "https://doi.org/10.1038/nature01012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/embo-reports/kvf056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048697087"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng887", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050756839", 
          "https://doi.org/10.1038/ng887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng887", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050756839", 
          "https://doi.org/10.1038/ng887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074365940", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074630047", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083343195", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2002-12", 
    "datePublishedReg": "2002-12-01", 
    "description": "Clustering of co-expressed, non-homologous genes on chromosomes implies their co-regulation. In lower eukaryotes, co-expressed genes are often found in pairs. Clustering of genes that share aspects of transcriptional regulation has also been reported in higher eukaryotes. To advance our understanding of the mode of coordinated gene regulation in multicellular organisms, we performed a genome-wide analysis of the chromosomal distribution of co-expressed genes in Drosophila. We identified a total of 1,661 testes-specific genes, one-third of which are clustered on chromosomes. The number of clusters of three or more genes is much higher than expected by chance. We observed a similar trend for genes upregulated in the embryo and in the adult head, although the expression pattern of individual genes cannot be predicted on the basis of chromosomal position alone. Our data suggest that the prevalent mechanism of transcriptional co-regulation in higher eukaryotes operates with extensive chromatin domains that comprise multiple genes.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nature01216", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2516646", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6916", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "420"
      }
    ], 
    "name": "Large clusters of co-expressed genes in the Drosophila genome", 
    "pagination": "666", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "4d48b103e14a59d889b2f7869a0f0dce37b4b78e9c210d3bcd2fc06b2b5cf4af"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "12478293"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nature01216"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1016219953"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nature01216", 
      "https://app.dimensions.ai/details/publication/pub.1016219953"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:25", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87106_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/nature01216"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nature01216'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nature01216'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nature01216'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nature01216'


 

This table displays all metadata directly associated to this object as RDF triples.

229 TRIPLES      21 PREDICATES      67 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nature01216 schema:about N00bb076a4453494d8de3db903a462611
2 N0822c7cfd94c47d78adcc7d248daa421
3 N099d8e7d327d46fbba257ba4a8add967
4 N105438fd654345b3bb6bc0cf19e5e66a
5 N121ec5ed2a7e47fdba3592803970633a
6 N1326803062d14080ae33180e85b4f65d
7 N3202730f4c0047de802afd1722251c77
8 N329a40287d8447f7bb994424deaadbac
9 N33ab9fdd34464653a509abc4bd0eeb2e
10 N52f87c0307614e8b8842e21e0d376896
11 N7b712d8f0074457d9af4f7fda2840263
12 N8e264aa9a7cf435da9fc2c20a053f773
13 N8eb5726abecf4980836261428665d8ac
14 Nb3c681f85fd44c1eac7e972aaaf53abb
15 Nb418a646d3824f3791f5d0385f9b1fb7
16 Nd046bfccbaac4ebba8cd2371e6d4fbe3
17 Nd7bf024e1e4e48c4826592ff0f268e66
18 Nfbe30f3d55e8476cadec132bf3db40f9
19 anzsrc-for:06
20 anzsrc-for:0604
21 schema:author Nbcd118af55ba492bb195cb7d45b31fe1
22 schema:citation sg:pub.10.1007/s00251-001-0374-z
23 sg:pub.10.1038/79896
24 sg:pub.10.1038/nature01012
25 sg:pub.10.1038/ng887
26 sg:pub.10.1186/1475-4924-1-5
27 https://app.dimensions.ai/details/publication/pub.1074365940
28 https://app.dimensions.ai/details/publication/pub.1074630047
29 https://app.dimensions.ai/details/publication/pub.1083343195
30 https://doi.org/10.1002/(sici)1098-2795(200006)56:2+<254::aid-mrd9>3.0.co;2-#
31 https://doi.org/10.1006/geno.2000.6254
32 https://doi.org/10.1016/s0962-8924(99)01693-1
33 https://doi.org/10.1016/s0968-0004(99)01516-9
34 https://doi.org/10.1016/s1097-2765(00)80114-8
35 https://doi.org/10.1016/s1097-2765(00)80431-1
36 https://doi.org/10.1074/jbc.275.18.13827
37 https://doi.org/10.1074/jbc.c100351200
38 https://doi.org/10.1074/jbc.c100765200
39 https://doi.org/10.1093/embo-reports/kvf056
40 https://doi.org/10.1101/gad.13.18.2339
41 https://doi.org/10.1128/mcb.20.1.312-318.2000
42 schema:datePublished 2002-12
43 schema:datePublishedReg 2002-12-01
44 schema:description Clustering of co-expressed, non-homologous genes on chromosomes implies their co-regulation. In lower eukaryotes, co-expressed genes are often found in pairs. Clustering of genes that share aspects of transcriptional regulation has also been reported in higher eukaryotes. To advance our understanding of the mode of coordinated gene regulation in multicellular organisms, we performed a genome-wide analysis of the chromosomal distribution of co-expressed genes in Drosophila. We identified a total of 1,661 testes-specific genes, one-third of which are clustered on chromosomes. The number of clusters of three or more genes is much higher than expected by chance. We observed a similar trend for genes upregulated in the embryo and in the adult head, although the expression pattern of individual genes cannot be predicted on the basis of chromosomal position alone. Our data suggest that the prevalent mechanism of transcriptional co-regulation in higher eukaryotes operates with extensive chromatin domains that comprise multiple genes.
45 schema:genre research_article
46 schema:inLanguage en
47 schema:isAccessibleForFree false
48 schema:isPartOf N015e24c1392544a0a64a64602db9b8b0
49 N1e10d667adad408a9872619b8079ceac
50 sg:journal.1018957
51 schema:name Large clusters of co-expressed genes in the Drosophila genome
52 schema:pagination 666
53 schema:productId N0176945b0e564936810694c9eac6d7bd
54 N6982d088119b434c8b9f51bb35f7226c
55 Nb3f1e82014104d38a6f4a2b15841ee33
56 Nb9adcf5b4b404f01a80fbf3f7b8b0882
57 Nbcf3a650dce14b88a9c6391de1a790cb
58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016219953
59 https://doi.org/10.1038/nature01216
60 schema:sdDatePublished 2019-04-11T12:25
61 schema:sdLicense https://scigraph.springernature.com/explorer/license/
62 schema:sdPublisher N5cbb21c311234a069e47d01741000dc2
63 schema:url https://www.nature.com/articles/nature01216
64 sgo:license sg:explorer/license/
65 sgo:sdDataset articles
66 rdf:type schema:ScholarlyArticle
67 N00bb076a4453494d8de3db903a462611 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Expressed Sequence Tags
69 rdf:type schema:DefinedTerm
70 N015e24c1392544a0a64a64602db9b8b0 schema:issueNumber 6916
71 rdf:type schema:PublicationIssue
72 N0176945b0e564936810694c9eac6d7bd schema:name readcube_id
73 schema:value 4d48b103e14a59d889b2f7869a0f0dce37b4b78e9c210d3bcd2fc06b2b5cf4af
74 rdf:type schema:PropertyValue
75 N0822c7cfd94c47d78adcc7d248daa421 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Testis
77 rdf:type schema:DefinedTerm
78 N099d8e7d327d46fbba257ba4a8add967 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Animals
80 rdf:type schema:DefinedTerm
81 N105438fd654345b3bb6bc0cf19e5e66a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name X Chromosome
83 rdf:type schema:DefinedTerm
84 N121ec5ed2a7e47fdba3592803970633a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Organ Specificity
86 rdf:type schema:DefinedTerm
87 N1326803062d14080ae33180e85b4f65d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Head
89 rdf:type schema:DefinedTerm
90 N1e10d667adad408a9872619b8079ceac schema:volumeNumber 420
91 rdf:type schema:PublicationVolume
92 N3202730f4c0047de802afd1722251c77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Male
94 rdf:type schema:DefinedTerm
95 N329a40287d8447f7bb994424deaadbac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Stochastic Processes
97 rdf:type schema:DefinedTerm
98 N33ab9fdd34464653a509abc4bd0eeb2e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Gene Expression Regulation, Developmental
100 rdf:type schema:DefinedTerm
101 N4c2af68654ef4c2086bff2780928e843 rdf:first sg:person.01204366760.82
102 rdf:rest N5855f41ebe564aa8aa3f947b7efe3c5c
103 N52f87c0307614e8b8842e21e0d376896 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Gene Expression Regulation
105 rdf:type schema:DefinedTerm
106 N5855f41ebe564aa8aa3f947b7efe3c5c rdf:first sg:person.0764716762.57
107 rdf:rest Nf3d6af961df8492195cee6291f8f9e0b
108 N5cbb21c311234a069e47d01741000dc2 schema:name Springer Nature - SN SciGraph project
109 rdf:type schema:Organization
110 N6982d088119b434c8b9f51bb35f7226c schema:name doi
111 schema:value 10.1038/nature01216
112 rdf:type schema:PropertyValue
113 N7b712d8f0074457d9af4f7fda2840263 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Genes, Insect
115 rdf:type schema:DefinedTerm
116 N8e264aa9a7cf435da9fc2c20a053f773 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Sex Characteristics
118 rdf:type schema:DefinedTerm
119 N8eb5726abecf4980836261428665d8ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Multigene Family
121 rdf:type schema:DefinedTerm
122 Nb3c681f85fd44c1eac7e972aaaf53abb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Gene Expression Profiling
124 rdf:type schema:DefinedTerm
125 Nb3f1e82014104d38a6f4a2b15841ee33 schema:name nlm_unique_id
126 schema:value 0410462
127 rdf:type schema:PropertyValue
128 Nb418a646d3824f3791f5d0385f9b1fb7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name RNA, Messenger
130 rdf:type schema:DefinedTerm
131 Nb9adcf5b4b404f01a80fbf3f7b8b0882 schema:name dimensions_id
132 schema:value pub.1016219953
133 rdf:type schema:PropertyValue
134 Nbcd118af55ba492bb195cb7d45b31fe1 rdf:first sg:person.0646110563.43
135 rdf:rest N4c2af68654ef4c2086bff2780928e843
136 Nbcf3a650dce14b88a9c6391de1a790cb schema:name pubmed_id
137 schema:value 12478293
138 rdf:type schema:PropertyValue
139 Nd046bfccbaac4ebba8cd2371e6d4fbe3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Genome
141 rdf:type schema:DefinedTerm
142 Nd7bf024e1e4e48c4826592ff0f268e66 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Chromatin
144 rdf:type schema:DefinedTerm
145 Nf3d6af961df8492195cee6291f8f9e0b rdf:first sg:person.01143017535.95
146 rdf:rest rdf:nil
147 Nfbe30f3d55e8476cadec132bf3db40f9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Drosophila melanogaster
149 rdf:type schema:DefinedTerm
150 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
151 schema:name Biological Sciences
152 rdf:type schema:DefinedTerm
153 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
154 schema:name Genetics
155 rdf:type schema:DefinedTerm
156 sg:grant.2516646 http://pending.schema.org/fundedItem sg:pub.10.1038/nature01216
157 rdf:type schema:MonetaryGrant
158 sg:journal.1018957 schema:issn 0090-0028
159 1476-4687
160 schema:name Nature
161 rdf:type schema:Periodical
162 sg:person.01143017535.95 schema:affiliation https://www.grid.ac/institutes/grid.429997.8
163 schema:familyName Nurminsky
164 schema:givenName Dmitry I.
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143017535.95
166 rdf:type schema:Person
167 sg:person.01204366760.82 schema:affiliation https://www.grid.ac/institutes/grid.4886.2
168 schema:familyName Kalmykova
169 schema:givenName Alla I.
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204366760.82
171 rdf:type schema:Person
172 sg:person.0646110563.43 schema:affiliation https://www.grid.ac/institutes/grid.429997.8
173 schema:familyName Boutanaev
174 schema:givenName Alexander M.
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0646110563.43
176 rdf:type schema:Person
177 sg:person.0764716762.57 schema:affiliation https://www.grid.ac/institutes/grid.4886.2
178 schema:familyName Shevelyov
179 schema:givenName Yuri Y.
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764716762.57
181 rdf:type schema:Person
182 sg:pub.10.1007/s00251-001-0374-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1018195584
183 https://doi.org/10.1007/s00251-001-0374-z
184 rdf:type schema:CreativeWork
185 sg:pub.10.1038/79896 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020624693
186 https://doi.org/10.1038/79896
187 rdf:type schema:CreativeWork
188 sg:pub.10.1038/nature01012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046557993
189 https://doi.org/10.1038/nature01012
190 rdf:type schema:CreativeWork
191 sg:pub.10.1038/ng887 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050756839
192 https://doi.org/10.1038/ng887
193 rdf:type schema:CreativeWork
194 sg:pub.10.1186/1475-4924-1-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001591994
195 https://doi.org/10.1186/1475-4924-1-5
196 rdf:type schema:CreativeWork
197 https://app.dimensions.ai/details/publication/pub.1074365940 schema:CreativeWork
198 https://app.dimensions.ai/details/publication/pub.1074630047 schema:CreativeWork
199 https://app.dimensions.ai/details/publication/pub.1083343195 schema:CreativeWork
200 https://doi.org/10.1002/(sici)1098-2795(200006)56:2+<254::aid-mrd9>3.0.co;2-# schema:sameAs https://app.dimensions.ai/details/publication/pub.1010633740
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1006/geno.2000.6254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007563541
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/s0962-8924(99)01693-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010391779
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/s0968-0004(99)01516-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012810908
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/s1097-2765(00)80114-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027451892
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/s1097-2765(00)80431-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008121454
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1074/jbc.275.18.13827 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023925037
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1074/jbc.c100351200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034846799
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1074/jbc.c100765200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044686949
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1093/embo-reports/kvf056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048697087
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1101/gad.13.18.2339 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014125903
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1128/mcb.20.1.312-318.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044800469
223 rdf:type schema:CreativeWork
224 https://www.grid.ac/institutes/grid.429997.8 schema:alternateName Tufts University
225 schema:name *Department of Anatomy & Cell Biology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
226 rdf:type schema:Organization
227 https://www.grid.ac/institutes/grid.4886.2 schema:alternateName Russian Academy of Sciences
228 schema:name †Department of Molecular Genetics of Animals, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow 123182, Russia
229 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...